Abstract:
:The aim of our study was to determine species and genotypes of Cryptosporidium in patients suffering from immunosuppressive illnesses, but also in immunocompetent patients suffering from diarrhoea. A total of 80 samples of faeces were collected from both immunosuppressed and immunocompetent patients. The immunosuppressed patients (65 samples) - 35 adult patients (group A) and 30 children (group B) were hospitalized at the Clinic of Oncohemathology. Samples from immunocompetent humans (15 samples, group C) were taken from patients with clinical signs of acute diarrhoea. With the use of molecular methods targeting the 60 kDa glycoprotein (GP60) gene region, we have identified multiple genotypes of Cryptosporidium. parvum and Cryptosporidium. hominis in immunocompromised, but also in immunocompetent individuals (C. hominis IbA10G2, IeA12G3T3; C. parvum IIaA10G1R1, IIaA11G2R1, IIaA12G2R1, IIaA13G1R1, IIaA14G1R1, IIaA14G2R1, IIaA17G1R1 and IIaA18G1R1). This is the first report of the occurrence of genotypes IIaA10G1R1, IIa12G2R1 and IIaA18G1R1 in human hosts.
journal_name
Transbound Emerg Disjournal_title
Transboundary and emerging diseasesauthors
Hatalová E,Valenčáková A,Luptáková L,Špalková M,Kalinová J,Halánová M,Bednárová V,Gabzdilová J,Dedinská K,Ondriska F,Boldiš Vdoi
10.1111/tbed.13009subject
Has Abstractpub_date
2019-01-01 00:00:00pages
243-249issue
1eissn
1865-1674issn
1865-1682journal_volume
66pub_type
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