Prognostic implications of histological tumor regression (Böhm's score) in patients receiving neoadjuvant chemotherapy for high grade serous tubal & ovarian carcinoma.

abstract：:The causes of death in long-term survivors after resection of cervical cancer were investigated in a follow-up study of 375 women, focusing especially on the postoperative development of second primary cancers. The 5- and 10-year overall survival rates were 75.0 and 66.0%, respectively, in cases that showed frank inva...

journal_title：Gynecologic oncology

authors： Tominaga K,Koyama Y,Sasagawa M,Obata N,Kamata H,Yamaguchi E,Nagai M

更新日期：1995-01-01 00:00:00

abstract：OBJECTIVE:Although treatment for advanced or recurrent endometrial carcinoma has improved over recent years with the introduction of paclitaxel- and platinum-based chemotherapy, in most, the disease remains incurable because of resistance to chemotherapy. In the previous study, we have shown that placental leucine amin...

journal_title：Gynecologic oncology

authors： Shibata K,Kikkawa F,Kondo C,Mizokami Y,Kajiyama H,Ino K,Nomura S,Mizutani S

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND:Primary appendiceal malignancy metastatic to the ovaries is a rare condition that may mimic late stage ovarian cancer. This condition is rarely diagnosed preoperatively. CASES:Three patients referred to our institution from 1994 to 1999 for presumed late stage ovarian cancer were found to have primary appen...

journal_title：Gynecologic oncology

authors： McBroom JW,Parker MF,Krivak TC,Rose GS,Crothers B

更新日期：2000-09-01 00:00:00

abstract：OBJECTIVES:Laminin-5 is an attachment protein for epithelial cells. Several studies of a variety of cancers have reported increased expression of laminin-5 in carcinoma in situ and invasive cancer. This study was designed to investigate the correlation between the grade of cervical intraepithelial neoplasia and the imm...

journal_title：Gynecologic oncology

authors： Kohlberger P,Beneder Ch,Horvat R,Leodolter S,Breitenecker G

更新日期：2003-06-01 00:00:00

abstract：INTRODUCTION:The benefit of adjuvant chemotherapy for Stage IC grade 1 and stage IA/IB grade 2 endometrioid ovarian adenocarcinoma (EOOC) remains unclear as the NCCN guidelines recommend either observation only or adjuvant chemotherapy. Therefore, we sought to determine whether patients with stage I EOOC had improved o...

journal_title：Gynecologic oncology

authors： Nasioudis D,Latif NA,Simpkins F,Cory L,Giuntoli RL 2nd,Haggerty AF,Morgan MA,Ko EM

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:To examine outcomes after pelvic exenteration in women treated with modern chemoradiation and surgical techniques. METHODS:All patients at our institution with a diagnosis of gynecologic malignancy who underwent pelvic exenteration after treatment with chemoradiation between 1/90 and 6/08 were evaluated wit...

journal_title：Gynecologic oncology

authors： McLean KA,Zhang W,Dunsmoor-Su RF,Shah CA,Gray HJ,Swensen RE,Goff BA

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:Metastatic bone involvement in vulvar squamous carcinoma is very rare. Here, we present a case of primary adenocarcinoma of the Bartholin's gland giving rise to isolated skull metastasis. CASE:A 74-year-old woman was referred with a diagnosis of primary vulvar adenocarcinoma of the right labium minus. A rig...

journal_title：Gynecologic oncology

authors： Ferrandina G,Testa AC,Zannoni GF,Poerio A,Scambia G

更新日期：2005-08-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to investigate the role of 2-[fluorine-18]-fluoro-2-deoxy-d-glucose positron emission tomography (FDG PET) in the diagnosis of recurrent ovarian cancer. METHODS:One hundred six FDG PET scans performed in 54 patients in the follow-up after cytoreductive surgery and chemotherapy of ova...

journal_title：Gynecologic oncology

authors： Zimny M,Siggelkow W,Schröder W,Nowak B,Biemann S,Rath W,Buell U

更新日期：2001-11-01 00:00:00

abstract：:Objective. Thegoal of this study was to determine the influence of LVSI (lymphvascular space involvement) on the risk of lymph node metastases from endometrial cancer.Methods. All patients with surgically staged endometrial cancer from 1998 to 2000 were identified from divisional databases. The influence of LVSI on th...

journal_title：Gynecologic oncology

authors： Cohn DE,Horowitz NS,Mutch DG,Kim SM,Manolitsas T,Fowler JM

更新日期：2002-12-01 00:00:00

abstract：OBJECTIVE:The purpose of the present study is to prospectively evaluate the effects of tamoxifen on the pathological behavior of endometrial hyperplasias without atypia, diagnosed before the start of adjuvant endocrine therapy, in menopausal patients suffering from breast cancer. METHODS:Twenty-six patients suffering ...

journal_title：Gynecologic oncology

authors： Garuti G,Cellani F,Centinaio G,Sita G,Nalli G,Luerti M

更新日期：2006-05-01 00:00:00

abstract：OBJECTIVES:We aimed to define the site-specific patterns of treatment failure in stage IV ovarian cancer. METHODS:Data from all consecutive Mayo Clinic patients with stage IV epithelial ovarian cancer, from 1994 through 2003, were collected and analyzed. Statistical analyses included the chi(2) test and Kaplan-Meier c...

journal_title：Gynecologic oncology

authors： Aletti GD,Podratz KC,Cliby WA,Gostout BS

更新日期：2009-01-01 00:00:00

abstract：PURPOSE:To evaluate the impact of the extension of the radiotherapy field cranially toward para-aortic lymph nodes (EF-RT) in advanced cervical cancer. MATERIALS AND METHODS:A systematic search of databases (PubMed, CENTRAL, Clinical Trials) was performed and included studies that were published between 1960 and Novem...

journal_title：Gynecologic oncology

authors： Sapienza LG,Gomes MJL,Calsavara VF,Leitao MM Jr,Baiocchi G

更新日期：2017-02-01 00:00:00

abstract：:A 20 year old with recurrent low-grade serous carcinoma (LGSC) is discussed. The differential diagnosis, pathology, epidemiology, treatment options are discussed. Focus on the molecular pathways of LGSC and the implications of the diagnosis on fertility are highlighted. ...

journal_title：Gynecologic oncology

authors： Cohn DE,Backes FJ,Wallbillich JJ,Bixel K,Crafton SM,Neff R,ElNaggar AC,Smith B,Suarez AA

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVE:Small cell carcinoma (SmCC) of the female genital tract constitutes a diagnostic and clinical challenge given its rarity and the lack of standardized therapeutic approaches. Here we review the morphological, clinical and molecular features of gynecologic SmCCs and discuss potential areas for future research. ...

journal_title：Gynecologic oncology

authors： Atienza-Amores M,Guerini-Rocco E,Soslow RA,Park KJ,Weigelt B

更新日期：2014-08-01 00:00:00

abstract：OBJECTIVE:Perform a systematic review to determine the test performance of HPV mRNA testing compared to DNA testing using CIN2+ as the target condition. METHODS:We searched bibliographic databases (MEDLINE, EMBASE and Cochrane Library) from January 1996 through August 2010 using a predefined search strategy. The refer...

journal_title：Gynecologic oncology

authors： Burger EA,Kornør H,Klemp M,Lauvrak V,Kristiansen IS

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:Primary non-gestational choriocarcinoma of the female genital tract has been described in the ovaries and is very unusual in other genital sites. CASE:Primary non-gestational uterine cervical choriocarcinoma was diagnosed in a patient, 32, single, without previous sexual contact nor antecedent pregnancy, ad...

journal_title：Gynecologic oncology

authors： Maestá I,Michelin OC,Traiman P,Hokama P,Rudge MV

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND:The prognosis of cancer patients with distant metastases is extremely poor. CASE:A 51-year-old Japanese woman with Stage IIIc serous cystoadenocarcinoma of the ovary achieved complete remission. At 30 and 39 months after the initiation of therapy, solitary brain and then spleen metastases without intraperit...

journal_title：Gynecologic oncology

authors： Mikami M,Suzuki A,Takehara K,Komiyama S,Ishikawa M,Hirose T

更新日期：2003-08-01 00:00:00

abstract：:Women with histopathologically confirmed cervical intraepithelial neoplasia (CIN) were followed at 3-month intervals in a randomized double-blinded trial to evaluate the efficacy of beta-carotene to cause regression of CIN. Questionnaire data, plasma levels of micronutrients, and a cervicovaginal lavage for human papi...

journal_title：Gynecologic oncology

authors： Romney SL,Ho GY,Palan PR,Basu J,Kadish AS,Klein S,Mikhail M,Hagan RJ,Chang CJ,Burk RD

更新日期：1997-06-01 00:00:00

abstract：:Ovarian carcinoma usually presents in an indolent manner, most often nonspecifically with complaints of abdominal pain or swelling, bloating, constipation, anorexia, early satiety, and evidence of ascites. We present a case of ovarian cancer with a cerebrovascular accident (CVA) as the presenting symptom, with minimal...

journal_title：Gynecologic oncology

authors： Shamonki MI,Squatrito RC,Welander CE

更新日期：1998-08-01 00:00:00

abstract：PURPOSE:The impact of gynecologic cancer on health-related quality of life (HRQOL) is not fully understood. To our knowledge, this is the first longitudinal study to measure HRQOL changes from before to after gynecologic cancer diagnosis in older women. METHODS:Data were obtained from the Surveillance, Epidemiology, a...

journal_title：Gynecologic oncology

authors： Klapheke AK,Keegan THM,Ruskin R,Cress RD

更新日期：2020-02-01 00:00:00

abstract：OBJECTIVE:The value of surgical staging of apparent early stage epithelial ovarian carcinoma (EOC) is unclear. The aim of this study was to evaluate the importance of surgical staging on the stage of disease and treatment plan. MATERIAL AND METHODS:All patients with apparent stage I EOC undergoing staging from 01/01/2...

journal_title：Gynecologic oncology

authors： Hengeveld EM,Zusterzeel PLM,Lajer H,Høgdall CK,Rosendahl M

更新日期：2019-08-01 00:00:00

abstract：OBJECTIVES:Fixed-dose rate gemcitabine plus docetaxel is active as second-line therapy for metastatic uterine leiomyosarcoma. We sought to determine the activity of this regimen as first-line treatment. METHODS:Eligible women with advanced uterine leiomyosarcoma were treated with gemcitabine 900 mg/m(2) over 90 min, o...

journal_title：Gynecologic oncology

authors： Hensley ML,Blessing JA,Mannel R,Rose PG

更新日期：2008-06-01 00:00:00

abstract：OBJECTIVE:Human papillomavirus (HPV) infection is the primary cause of cervical cancer. HPV-mediated immune alterations are known to play crucial roles in determining viral persistence and host cell transformation. We sought to thoroughly understand HPV-directed immune alterations in cervical cancer by exploring public...

journal_title：Gynecologic oncology

authors： Chen L,Luan S,Xia B,Liu Y,Gao Y,Yu H,Mu Q,Zhang P,Zhang W,Zhang S,Wei G,Yang M,Li K

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVE:MicroRNA (miRNA) plays an essential role in the progression of a variety of cancers, but its role in cervical cancer progression is not well defined. We aimed to test whether special miRNAs and their target mRNAs contribute to cervical cancer progression. METHODS:The expression profiles of 1145 microRNAs in ...

journal_title：Gynecologic oncology

authors： Li JH,Xiao X,Zhang YN,Wang YM,Feng LM,Wu YM,Zhang YX

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:The aberrant expression of hepatocyte growth factor and its receptor c-Met are associated with aggressive disease and poor prognosis in a variety of human malignancies including ovarian cancer (OC). Specificity protein (Sp) transcription factors have high relevance in the signaling cascade associated with c-M...

journal_title：Gynecologic oncology

authors： Basha R,Ingersoll SB,Sankpal UT,Ahmad S,Baker CH,Edwards JR,Holloway RW,Kaja S,Abdelrahim M

更新日期：2011-07-01 00:00:00

abstract：OBJECTIVE:To compare the oncologic outcome of women who underwent fertility-sparing surgery (FSS) vs. radical surgery (RS) for treatment of NEOC in a prospective, nationwide, population-based study and report on the reproductive outcomes in women after FSS. METHODS:Using the Swedish Quality Register for Gynecological ...

journal_title：Gynecologic oncology

authors： Johansen G,Dahm-Kähler P,Staf C,Flöter Rådestad A,Rodriguez-Wallberg KA

更新日期：2019-11-01 00:00:00

abstract：:Adriamycin (50 mg/m2) and cis-diamminedichloroplatinum (50 mg/m2) were administered every 21 days to treat metastatic endometrial adenocarcinoma. This regimen resulted in three responses (one complete and two partial) in nine women (33%). Most patients had moderate or severe hematologic and gastrointestinal toxicity. ...

journal_title：Gynecologic oncology

authors： Seltzer V,Vogl SE,Kaplan BH

更新日期：1984-11-01 00:00:00

abstract：OBJECTIVE:Human papillomavirus (HPV) infection play a significant role in cervical carcinogenesis, and HPV oncoprotein E7 has important functions in the formation and maintenance of cervical cancers. Interleukin-12 (IL-12) has been reported to induce cellular immune responses, and has also been demonstrated to suppress...

journal_title：Gynecologic oncology

authors： Jin HS,Park EK,Lee JM,NamKoong SE,Kim DG,Lee YJ,Jun HJ,Han BD,Bae SM,Ahn WS

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:The incidence of postoperative delirium (PD) in the elderly ranges between 3-60% but has never been examined in gynecologic oncology. Our goal was to identify pre, intra, and postoperative risk factors associated with the development of PD. METHODS:English speaking women of 60 years and above undergoing maj...

journal_title：Gynecologic oncology

authors： McAlpine JN,Hodgson EJ,Abramowitz S,Richman SM,Su Y,Kelly MG,Luther M,Baker L,Zelterman D,Rutherford TJ,Schwartz PE

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:Traditionally, hysterectomy is considered definitive therapy for cervical adenocarcinoma in situ (AIS) in women beyond childbearing. CASE:A 45-year-old gravida 2, para 2 patient presented with cervical dysplasia and on pathology review of the large loop excision procedure cervical adenocarcinoma in situ was...

journal_title：Gynecologic oncology

authors： Miller B,Dunn J,Dalrymple J,Krivak TC

更新日期：2005-11-01 00:00:00