Abstract:
OBJECTIVES:The overlapping symptoms of Parkinson's disease (PD) and progressive supranuclear palsy-Richardson's syndrome (PSP-RS) often make a correct clinical diagnosis difficult. The volume of subcortical brain structures derived from high-resolution T1-weighted magnetic resonance imaging (MRI) datasets is frequently used for individual level classification of PD and PSP-RS patients. The aim of this study was to evaluate the benefit of including additional morphological features beyond the simple regional volume, as well as clinical features, and morphological features of cortical structures for an automatic classification of PD and PSP-RS patients. MATERIAL AND METHODS:A total of 98 high-resolution T1-weighted MRI datasets from 76 PD patients, and 22 PSP-RS patients were available for this study. Using an atlas-based approach, the volume, surface area, and surface-area-to-volume ratio (SA:V) of 21 subcortical and 48 cortical brain regions were calculated and used as features for a support vector machine classification after application of a RELIEF feature selection method. RESULTS:The comparison of the classification results suggests that including all three morphological parameters (volume, surface area and SA:V) can considerably improve classification accuracy compared to using volume or surface area alone. Likewise, including clinical patient features in addition to morphological parameters also considerably increases the classification accuracy. In contrast to this, integrating morphological features of other cortical structures did not lead to improved classification accuracy. Using this optimal set-up, an accuracy of 98% was achieved with only one falsely classified PD and one falsely classified PSP-RS patient. CONCLUSION:The results of this study suggest that clinical features as well as more advanced morphological features should be used for future computer-aided diagnosis systems to differentiate PD and PSP-RS patients based on morphological parameters.
journal_name
Clin Neuroradioljournal_title
Clinical neuroradiologyauthors
Talai AS,Ismail Z,Sedlacik J,Boelmans K,Forkert NDdoi
10.1007/s00062-018-0727-8subject
Has Abstractpub_date
2019-12-01 00:00:00pages
605-614issue
4eissn
1869-1439issn
1869-1447pii
10.1007/s00062-018-0727-8journal_volume
29pub_type
杂志文章abstract:PURPOSE:The optimal strategy for the treatment of M1 segment aneurysms has not yet been determined as both standard microneurosurgical and endovascular techniques can pose challenges. We sought to determine the efficacy of flow diverting stents to treat small, unruptured aneurysms of the M1 segment. METHODS:We retrosp...
journal_title:Clinical neuroradiology
pub_type: 杂志文章
doi:10.1007/s00062-016-0553-9
更新日期:2018-06-01 00:00:00
abstract:PURPOSE:Computed tomography (CT) accounts for more than half of the total radiation exposure from medical procedures, which makes dose reduction in CT an effective means of reducing radiation exposure. We analysed the dose reduction that can be achieved with a new CT scanner [Somatom Edge (E)] that incorporates new dev...
journal_title:Clinical neuroradiology
pub_type: 杂志文章
doi:10.1007/s00062-013-0263-5
更新日期:2014-03-01 00:00:00
abstract:PURPOSE:The low-profile Acandis Acclino is a self-expandable nitinol microstent for stent-assisted coiling of intracranial aneurysms. This article reports long-term clinical and angiographic outcome in a multicenter setting. METHODS:In this study 98 consecutive patients (mean age 55.4 ± 13.5 years) were treated with t...
journal_title:Clinical neuroradiology
pub_type: 杂志文章
doi:10.1007/s00062-019-00847-4
更新日期:2020-12-01 00:00:00
abstract::The technology available for the endovascular treatment of intracranial aneurysms is rapidly evolving. Both current and future devices are described. This includes, among others, UNO for parent vessel occlusion, the Medina device for saccular filling, the Comaneci device for remodeling, pCONus for assisted coil occlus...
journal_title:Clinical neuroradiology
pub_type: 杂志文章,评审
doi:10.1007/s00062-015-0403-1
更新日期:2015-10-01 00:00:00
abstract:INTRODUCTION:Diffusion-weighted imaging (DWI) produces contrast among different kinds of tissues according to their diffusibility characteristics. The purpose of our study was to evaluate the role of DWI including measurement of apparent diffusion coefficient (ADC) values in recognizing benignancy or malignancy of orbi...
journal_title:Clinical neuroradiology
pub_type: 杂志文章
doi:10.1007/s00062-013-0234-x
更新日期:2014-06-01 00:00:00
abstract:PURPOSE:Visualization of the abducens nerve in its petroclival segment still remains challenging. We aimed to investigate the detectability of the petroclival segment of the abducens nerve and to evaluate the role of the size of the petroclival venous confluence (PVC) in the visibility of the nerve using contrast-enhan...
journal_title:Clinical neuroradiology
pub_type: 杂志文章
doi:10.1007/s00062-015-0415-x
更新日期:2017-03-01 00:00:00
abstract:PURPOSE:The authors investigated the potential of a 32-channel (32ch) receiving head coil for functional magnetic resonance imaging (fMRI) compared to a standard eight-channel (8ch) coil using a motor task. MATERIAL AND METHODS:Brain activation was analyzed in 14 healthy right-handed subjects performing finger tapping...
journal_title:Clinical neuroradiology
pub_type: 杂志文章
doi:10.1007/s00062-010-0029-2
更新日期:2010-12-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Several studies have shown that thrombectomy is safe and effective in occlusions of the M2 segment of the middle cerebral artery. This retrospective study compared superior and inferior division occlusions regarding radiological and clinical outcomes. METHODS:Between 2009 and 2017, patients trea...
journal_title:Clinical neuroradiology
pub_type: 杂志文章
doi:10.1007/s00062-019-00767-3
更新日期:2020-06-01 00:00:00
abstract::Conventional magnetic resonance (MR) imaging of space-occupying lesions may answer most of the questions concerning the diagnosis and subsequent treatment strategies if patient age, clinical and paraclinical findings are considered as well. However, crucial and relevant differential diagnoses require additional MR met...
journal_title:Clinical neuroradiology
pub_type: 杂志文章,评审
doi:10.1007/s00062-011-0073-6
更新日期:2011-09-01 00:00:00
abstract:OBJECTIVE:Tinnitus is defined as an imaginary subjective perception in the absence of an external sound. Convergent evidence proposes that tinnitus perception includes auditory, attentional and emotional components. The aim of this study was to investigate the thalamic, auditory and limbic interactions associated with ...
journal_title:Clinical neuroradiology
pub_type: 杂志文章
doi:10.1007/s00062-015-0473-0
更新日期:2017-06-01 00:00:00
abstract:PURPOSE:Against the background of the increasing dilemma in the scientific community regarding protected versus unprotected carotid artery stent (CAS) placement and the disputed points in interpreting the results of scientific studies as well as the difficulty in conducting such randomized controlled studies, this arti...
journal_title:Clinical neuroradiology
pub_type: 杂志文章
doi:10.1007/s00062-011-0057-6
更新日期:2011-06-01 00:00:00
abstract:PURPOSE:Knowledge about the localization and outcome of iatrogenic dissection (ID) during endovascular treatment of acute ischemic stroke (AIS) is limited. We aimed to determine the frequency, clinical aspects and morphology of ID in endovascular AIS treatment and to identify predictors of this complication. METHODS:D...
journal_title:Clinical neuroradiology
pub_type: 杂志文章
doi:10.1007/s00062-017-0639-z
更新日期:2019-03-01 00:00:00
abstract:PURPOSE:The purpose of this study was to determine potential effects of isometric non-machine-based training on the cross-sectional area (CSA) of the paravertebral muscles in volunteers who were participants in a prevention program. An increase in the CSA of back muscles after various machine-based exercises have been ...
journal_title:Clinical neuroradiology
pub_type: 杂志文章
doi:10.1007/s00062-011-0104-3
更新日期:2011-11-01 00:00:00
abstract:PURPOSE:Internal jugular vein (IJV) narrowing superiorly is likely relatively frequent. IJV narrowing has been proposed as a potential pathophysiologic component for multiple sclerosis (MS). Our purpose was to investigate the prevalence of incidental superior IJV narrowing in patients imaged with neck computed tomograp...
journal_title:Clinical neuroradiology
pub_type: 杂志文章
doi:10.1007/s00062-013-0232-z
更新日期:2014-06-01 00:00:00
abstract:PURPOSE:Our aim was to identify imaging characteristics of pilocytic astrocytomas (PAs) in the cerebral ventricles to help radiologists distinguish PAs from other brain tumors preoperatively. METHODS:Twelve postsurgery patients with a pathological PA diagnosis were included. Among them, 10 had submitted to surgery bas...
journal_title:Clinical neuroradiology
pub_type: 杂志文章
doi:10.1007/s00062-015-0370-6
更新日期:2016-09-01 00:00:00
abstract:PURPOSE:Patients with transient global amnesia (TGA) present with a characteristic clinical syndrome although other differential diagnoses have to be considered. Diffusion-weighted imaging (DWI) represents a highly specific diagnostic tool in the context of TGA; however, standard clinical DWI often fails to detect the ...
journal_title:Clinical neuroradiology
pub_type: 杂志文章
doi:10.1007/s00062-012-0140-7
更新日期:2012-12-01 00:00:00
abstract:PURPOSE:Stroke is a rising cause of mortality in human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS) populations. The etiology of stroke remains at the core of the decision-making process to treat and prevent recurrent events. In this population HIV vasculopathy (HIV-V) and varicella zoster...
journal_title:Clinical neuroradiology
pub_type: 杂志文章
doi:10.1007/s00062-011-0087-0
更新日期:2011-09-01 00:00:00
abstract:PURPOSE:Tethered cord syndrome (TCS) is a clinical entity in which symptoms are induced through excessive tension on the spinal cord. The radiological method of choice to confirm TCS is magnetic resonance imaging (MRI), however limitations exist especially in patients with no underlying spinal dysraphism. MATERIALS AN...
journal_title:Clinical neuroradiology
pub_type: 杂志文章
doi:10.1007/s00062-010-0049-y
更新日期:2011-04-01 00:00:00
abstract:PURPOSE:Since the incidental discovery and systematic introduction of mechanical endovascular stroke treatment in 2015 there are few reports about the real-life situation in daily clinical practice. The aim of this study was to evaluate the mechanical thrombectomy data documented in the quality assurance database of th...
journal_title:Clinical neuroradiology
pub_type: 杂志文章
doi:10.1007/s00062-020-00989-w
更新日期:2021-01-22 00:00:00
abstract:OBJECTIVE:To illustrate the added value of flat-detector computed tomography angiography with intravenous contrast media injection (intravenous FDCTA) in the evaluation of complex A1/A2/AcomA aneurysms. PATIENTS AND METHODS:We retrospectively reviewed 15 patients with ruptured aneurysms. In each patient, an intravenou...
journal_title:Clinical neuroradiology
pub_type: 杂志文章
doi:10.1007/s00062-017-0592-x
更新日期:2018-12-01 00:00:00
abstract:PURPOSE:The aim of this study is to evaluate the association between lesion progression and the ischemic or edematous area that can develop around the hemorrhage in intraparenchymal hemorrhagic lesions originating after head trauma. METHODS:Thirty patients with intracerebral hemorrhage due to head trauma of a mild or ...
journal_title:Clinical neuroradiology
pub_type: 杂志文章
doi:10.1007/s00062-013-0251-9
更新日期:2014-12-01 00:00:00
abstract::The report concerns a 44-year-old female patient with incidental left middle cerebral artery aneurysm. After endovascular therapy by coiling, a hemiparesis was observed following extubation. Disturbance of speech and disorientation added later. An infarct of the lenticular nucleus was found. The angiography showed an ...
journal_title:Clinical neuroradiology
pub_type: 杂志文章
doi:10.1007/s00062-010-0007-8
更新日期:2010-06-01 00:00:00
abstract:PURPOSE:The aim of this study was to compare vertebral failure loads, predicted from finite element (FE) analysis of patients with and without osteoporotic vertebral fractures (OVF) at virtually reduced dose levels, compared to standard-dose exposure from multidetector computed tomography (MDCT) imaging and evaluate wh...
journal_title:Clinical neuroradiology
pub_type: 杂志文章
doi:10.1007/s00062-018-0722-0
更新日期:2019-12-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Extracranial internal carotid artery (ICA) dissection is an important cause of ischemic stroke in younger adults. The optimal medical and surgical strategies for managing these lesions have not been well established. We report a case series of extracranial ICA reconstruction using overlapping flo...
journal_title:Clinical neuroradiology
pub_type: 杂志文章
doi:10.1007/s00062-018-0707-z
更新日期:2019-12-01 00:00:00
abstract:PURPOSE:Isolated posterior inferior cerebellar artery dissecting aneurysms are rare lesions. Their underlying pathology, presentation, and natural history are poorly understood. Their treatment is controversial, and few data are available regarding the best treatment. We conducted the first study comparing selective co...
journal_title:Clinical neuroradiology
pub_type: 杂志文章
doi:10.1007/s00062-013-0247-5
更新日期:2014-09-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Mechanical thrombectomy is an effective recanalization technique in acute ischemic stroke patients with large vessel occlusions; however, it is unclear to what extent stent retriever thrombectomy may be applicable to occlusions of smaller peripheral cerebral vessels. The outcome of patients with ...
journal_title:Clinical neuroradiology
pub_type: 杂志文章
doi:10.1007/s00062-018-0739-4
更新日期:2020-03-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The estimates on the risk of rupture of intracranial aneurysms remain a controversial topic. Circumferential aneurysmal wall enhancement (CAWE) on vessel wall magnetic resonance imaging (MRI) has been described in unstable aneurysms. Sentinel headaches and third nerve palsy are possible symptoms ...
journal_title:Clinical neuroradiology
pub_type: 杂志文章
doi:10.1007/s00062-017-0598-4
更新日期:2018-12-01 00:00:00
abstract:BACKGROUND AND PURPOSE:As magnetic resonance imaging (MRI) signs of normal pressure hydrocephalus (NPH) may precede clinical symptoms we sought to evaluate an algorithm that automatically detects this pattern. METHODS:A support vector machine (SVM) was trained in 30 NPH patients treated with ventriculoperitoneal shunt...
journal_title:Clinical neuroradiology
pub_type: 杂志文章
doi:10.1007/s00062-020-00993-0
更新日期:2021-01-26 00:00:00
abstract:PURPOSE:Diagnosis of cortical vein thrombosis (CVT) on the basis of clot hyperintensity on diffusion-weighted imaging (DWI) has been reported as limited. Our aim was to evaluate different DWI findings of CVT either in isolated form or in combination with sinus thrombosis. METHODS:In this review-board-approved study, p...
journal_title:Clinical neuroradiology
pub_type: 杂志文章
doi:10.1007/s00062-014-0301-y
更新日期:2015-09-01 00:00:00
abstract:PURPOSE:Acute major stroke with high-grade stenosis or occlusion of the extracranial internal carotid artery (ICA) and additional intracranial large artery occlusion is increasingly treated with a mechanical endovascular approach by extracranial stenting and intracranial thrombectomy due to poor response to systemic th...
journal_title:Clinical neuroradiology
pub_type: 临床试验,杂志文章
doi:10.1007/s00062-014-0318-2
更新日期:2015-12-01 00:00:00