[Pulmonary tuberculosis: Radiological evolution of broncho-pulmonary lesions at the end of treatment].

Abstract:

OBJECTIVES:To describe the residual broncho-pulmonary lesions and evaluate the role of CT scanning at the end of treatment of pulmonary tuberculosis. MATERIALS AND METHODS:Analysis of the initial and end of treatment CT scans of 56 patients with pulmonary tuberculosis according to a reading grid including parenchymatous and airways lesions. The CT data at the end of treatment were analysed in relation to the clinical and microbiological data, and the original CT scan. RESULTS:Active lesions (thick walled cavities and/or centrilobular micronodules) persisted in 24 patients (43%) after a mean treatment period of 7 months. The persistence of these signs of activity was correlated with the initial presence of a cavitary syndrome (p=0.027), with predominant sub-segmentary bronchial involvement, with extensive micronodular spread (p=0.024) and with bronchiectasis (p=0.04). These residual lesions were not associated with an increased risk of relapse. CONCLUSION:The persistence of signs of activity on the CT scan at the end of treatment of tuberculosis do not necessarily correspond to an absence of cure but to a radiological delay. This imaging is nevertheless useful to make an assessment of any subsequent changes in the bronchial tree and to estimate the risk of later complications.

journal_name

Rev Mal Respir

authors

Méchaï F,Fock-Yee C,Bouvry D,Raffetin A,Bouchaud O,Brauner M,Brillet PY

doi

10.1016/j.rmr.2018.08.005

subject

Has Abstract

pub_date

2019-01-01 00:00:00

pages

22-30

issue

1

eissn

0761-8425

issn

1776-2588

pii

S0761-8425(18)30267-5

journal_volume

36

pub_type

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