Abstract:
:The number of patients with end-stage heart failure (HF) continues to increase over time, but there has been little change in the availability of organs for cardiac transplantation, intensifying the demand for left ventricular assist devices (LVADs) as a bridge to transplantation. There is also a growing number of patients with end-stage HF who are not transplant candidates but may be eligible for long-term support with an LVAD, known as destination therapy. Due to this increasing demand, LVAD technology has evolved, resulting in transformative improvements in outcomes. Additionally, with growing clinical experience patient management continues to be refined, leading to iterative improvements in outcomes. With outcomes continuing to improve, the potential benefit from LVAD therapy is being considered for patients earlier in their course of advanced HF. We review recent changes in technology, patient management, and implant decision making in LVAD therapy.
journal_name
Annu Rev Medjournal_title
Annual review of medicineauthors
Miller RJH,Teuteberg JJ,Hunt SAdoi
10.1146/annurev-med-041217-011015subject
Has Abstractpub_date
2019-01-27 00:00:00pages
33-44eissn
0066-4219issn
1545-326Xjournal_volume
70pub_type
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