Abstract:
BACKGROUND:Mobility limitations are frequent in patients with multiple sclerosis (MS), and could already be present in patients with so-called mild neurological disability (Expanded Disability Status Scale≤4). Assessing mobility in these patients is therefore of paramount importance. Timed Up-and-Go Test (TUG) and 2-Minute Walk Test (2MWT) are two clinically feasible tests which reliability and responsiveness are unknown among these patients. Whether fatigue, which is the number one symptom among these patients, is linked to these limitations remains unknown. AIM:The aim of this study was to explore the intrarater reliability and minimal detectable change (MDC95), as an index of responsiveness, of TUG and 2MWT. To explore their link with perceived fatigue among patients with MS. DESIGN:Cross-sectional observational study, including two measures. SETTING:Two university hospital outpatient centers. POPULATION:Patients (N.=63, 49 seen twice) with MS with mild disability (Expanded Disability Status Scale≤4). METHODS:2MWT and TUG were performed twice in one occasion, and repeated 2 weeks later. Modified fatigue impact scale (MFIS) was used to assess fatigue. Intraclass coefficient correlations were calculated for immediate and 2-week reliability. MDC95 were computed. Correlations between mobility indices and fatigue were explored using Spearman's ρ. RESULTS:Mobility was impaired in comparison to normative values (2MWT: -4.9% from normative distance; TUG: +32% from normative time). The immediate reliability was excellent for both the 2MWT (ICC=0.98) and TUG (ICC=0.98). Reliability at 2 weeks was excellent for 2MWT (ICC=0.95) and very good for TUG (ICC=0.90). MDC95 were respectively 20m (2MWT) and 1.3s (TUG). Both measures were significantly weakly correlated to total MFIS (ρ=-0.37 and 0.39, respectively; P<0.01). CONCLUSIONS:The 2MWT and TUG are highly reliable and responsive in the assessment of respectively the walking capacity and general mobility of patients with MS with mild disability. Mobility impairments are linked to perceived fatigue among these patients. CLINICAL REHABILITATION IMPACT:TUG and 2MWT are easy to administer and could be reliably used in so called mildly disabled patients with MS to assess mobility limitation.
journal_name
Eur J Phys Rehabil Medjournal_title
European journal of physical and rehabilitation medicineauthors
Valet M,Lejeune T,Devis M,van Pesch V,El Sankari S,Stoquart Gdoi
10.23736/S1973-9087.18.05366-2subject
Has Abstractpub_date
2019-08-01 00:00:00pages
450-455issue
4eissn
1973-9087issn
1973-9095pii
S1973-9087.18.05366-2journal_volume
55pub_type
杂志文章abstract::On the occasion of the 150th Anniversary of the Italian Unification, the discovery of some letters by Giuseppe Garibaldi - referring to a period of thermal treatments at the Baths in Civitavecchia (Rome) - gave us the opportunity for writing a commentary about a not well known experience in the Two World Hero's life: ...
journal_title:European journal of physical and rehabilitation medicine
pub_type: 传,历史文章,杂志文章
doi:
更新日期:2011-12-01 00:00:00
abstract:BACKGROUND:Despite the positive health effects of (intensive) exercise in patients with inflammatory rheumatic diseases, they are very often inactive. Motivational exercise interventions in other patient samples have shown good effects in promoting exercise behaviours. AIM:To evaluate the short- and long-term effects ...
journal_title:European journal of physical and rehabilitation medicine
pub_type: 杂志文章
doi:
更新日期:2014-08-01 00:00:00
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journal_title:European journal of physical and rehabilitation medicine
pub_type: 杂志文章
doi:
更新日期:2015-10-01 00:00:00
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journal_title:European journal of physical and rehabilitation medicine
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journal_title:European journal of physical and rehabilitation medicine
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更新日期:2011-09-01 00:00:00
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journal_title:European journal of physical and rehabilitation medicine
pub_type: 杂志文章
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journal_title:European journal of physical and rehabilitation medicine
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journal_title:European journal of physical and rehabilitation medicine
pub_type: 杂志文章
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更新日期:2013-08-01 00:00:00
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journal_title:European journal of physical and rehabilitation medicine
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更新日期:2013-06-01 00:00:00
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journal_title:European journal of physical and rehabilitation medicine
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journal_title:European journal of physical and rehabilitation medicine
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journal_title:European journal of physical and rehabilitation medicine
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journal_title:European journal of physical and rehabilitation medicine
pub_type: 杂志文章
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更新日期:2013-10-01 00:00:00
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journal_title:European journal of physical and rehabilitation medicine
pub_type: 杂志文章,评审
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journal_title:European journal of physical and rehabilitation medicine
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journal_title:European journal of physical and rehabilitation medicine
pub_type: 历史文章,杂志文章
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更新日期:2010-06-01 00:00:00
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pub_type: 杂志文章,meta分析,评审
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更新日期:2015-12-01 00:00:00
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journal_title:European journal of physical and rehabilitation medicine
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更新日期:2010-06-01 00:00:00
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journal_title:European journal of physical and rehabilitation medicine
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journal_title:European journal of physical and rehabilitation medicine
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journal_title:European journal of physical and rehabilitation medicine
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更新日期:2012-09-01 00:00:00
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journal_title:European journal of physical and rehabilitation medicine
pub_type: 杂志文章,随机对照试验
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journal_title:European journal of physical and rehabilitation medicine
pub_type: 杂志文章
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journal_title:European journal of physical and rehabilitation medicine
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更新日期:2018-08-01 00:00:00
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journal_title:European journal of physical and rehabilitation medicine
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