Abstract:
:Glutathione (GSH), often referred to as "the master antioxidant," participates not only in antioxidant defense systems, but many metabolic processes, and therefore its role cannot be overstated. GSH deficiency causes cellular risk for oxidative damage and thus as expected, GSH imbalance is observed in a wide range of pathological conditions including tuberculosis (TB), HIV, diabetes, cancer, and aging. Consequently, it is not surprising that GSH has attracted the attention of biological researchers and pharmacologists alike as a possible target for medical intervention. Here, we discuss the role GSH plays amongst these pathological conditions to illuminate how it can be used as a marker for human disease.
journal_name
Adv Clin Chemjournal_title
Advances in clinical chemistryauthors
Teskey G,Abrahem R,Cao R,Gyurjian K,Islamoglu H,Lucero M,Martinez A,Paredes E,Salaiz O,Robinson B,Venketaraman Vdoi
10.1016/bs.acc.2018.07.004subject
Has Abstractpub_date
2018-01-01 00:00:00pages
141-159eissn
0065-2423issn
2162-9471pii
S0065-2423(18)30039-8journal_volume
87pub_type
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