Resveratrol significantly inhibits the occurrence and development of cervical cancer by regulating phospholipid scramblase 1.

Abstract:

:Cervical cancer (CC) is one of the most common female malignancies, and resveratrol is a polyphenol isolated from the skins of grapes, which has been reported to significantly alter the cellular physiology of tumor cells. However, little is known about the role of phospholipid scramblase 1 (PLSCR1) in pathogenesis of CC. Here, we demonstrated that resveratrol could significantly inhibit both the growth of HeLa cells and expression of PLSCR1. These results suggest that resveratrol-mediated cell growth inhibition can be regulated by PLSCR1.

journal_name

J Cell Biochem

authors

Zhao Y,Yuan X,Li X,Zhang Y

doi

10.1002/jcb.27335

subject

Has Abstract

pub_date

2018-10-22 00:00:00

eissn

0730-2312

issn

1097-4644

pub_type

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