Demyelinating neuropathy due to primary IgM kappa B cell lymphoma of peripheral nerve.

abstract：:We studied lymphocyte subsets and major histocompatibility complex (MHC) class II antigens in frozen brain tissues from three patients with subacute sclerosing panencephalitis (SSPE) using immunocytochemical techniques. Perivascular cuffs consisted predominantly of T cells and MHC class II-positive cells. In the paren...

journal_title：Neurology

authors： Nagano I,Nakamura S,Yoshioka M,Kogure K

更新日期：1991-10-01 00:00:00

abstract：:Neurofibromatosis 2 (NF2), a dominantly inherited disorder, typically manifests as bilateral vestibular schwannomas and predisposes to other nervous system tumors. In this study, we present a large pedigree with a benign course of NF2 (mild Gardner type) characterized by slowly growing vestibular schwannomas but few o...

journal_title：Neurology

authors： Sainio M,Strachan T,Blomstedt G,Salonen O,Setälä K,Palotie A,Palo J,Pyykkö I,Peltonen L,Jääskeläinen J

更新日期：1995-07-01 00:00:00

abstract：:Plasma levels of six short-chain fatty acids (SCFA) were measured in 23 Reye's syndrome patients. In sequential measurements, only propionic acid correlated closely with neurologic severity. Although admission SCFA levels were slightly elevated, there were no significant differences between patients grouped by severit...

journal_title：Neurology

authors： McArthur B,Sarnaik AP,Mitchell RA

更新日期：1984-06-01 00:00:00

abstract：OBJECTIVE:The primary objective of this research was to characterize the movement disorders associated with FOXG1 mutations. METHODS:We identified patients with FOXG1 mutations who were referred to either a tertiary movement disorder clinic or tertiary epilepsy service and retrospectively reviewed medical records, cli...

journal_title：Neurology

authors： Papandreou A,Schneider RB,Augustine EF,Ng J,Mankad K,Meyer E,McTague A,Ngoh A,Hemingway C,Robinson R,Varadkar SM,Kinali M,Salpietro V,O'Driscoll MC,Basheer SN,Webster RI,Mohammad SS,Pula S,McGowan M,Trump N,Jenkin

更新日期：2016-05-10 00:00:00

abstract：BACKGROUND:Although phenylketonuria is a treatable disease, patients with late or nonoptimal phenylalanine-restricted diet may experience brain damage. The authors used tridimensional MRI and a voxelwise analysis method to investigate possible volume changes in the brain parenchyma of patients with phenylketonuria. ME...

journal_title：Neurology

authors： Pérez-Dueñas B,Pujol J,Soriano-Mas C,Ortiz H,Artuch R,Vilaseca MA,Campistol J

更新日期：2006-04-11 00:00:00

abstract：:Interictal and ictal fluorodeoxyglucose scans were obtained with positron CT from four patients with spontaneous recurrent partial seizures, one with epilepsia partialis continua, and one with a single partial seizure induced by electrical stimulation of the hippocampus. Ictal metabolic patterns were different for eac...

journal_title：Neurology

authors： Engel J Jr,Kuhl DE,Phelps ME,Rausch R,Nuwer M

更新日期：1983-04-01 00:00:00

abstract：:Somnolence and "sleep attacks" have been reported as an adverse effect of several antiparkinsonian drugs. The authors document, in a placebo-controlled, randomized, double-blind, crossover study performed in 20 healthy volunteers, using the Multiple System Latency Test (MSLT) as primary outcome, that ropinirole reduce...

journal_title：Neurology

authors： Ferreira JJ,Galitzky M,Thalamas C,Tiberge M,Montastruc JL,Sampaio C,Rascol O

更新日期：2002-02-12 00:00:00

abstract：OBJECTIVE:To characterize children with new-onset seizures presenting as status epilepticus at a tertiary care children's hospital. METHODS:Prospectively collected data were reviewed from a database derived from a mandated critical care pathway. A total of 1,382 patients presented with new-onset seizures between 2001 ...

journal_title：Neurology

authors： Singh RK,Stephens S,Berl MM,Chang T,Brown K,Vezina LG,Gaillard WD

更新日期：2010-02-23 00:00:00

abstract：:We report a Japanese boy with muscular dystrophy whose clinical symptoms were intermediate between those usually considered typical of Duchenne and Becker muscular dystrophies. The patient had a large inframe deletion extending from exons 3 to 41 of the dystrophin gene, which would be expected to cause the production ...

journal_title：Neurology

authors： Takeshima Y,Nishio H,Narita N,Wada H,Ishikawa Y,Ishikawa Y,Minami R,Nakamura H,Matsuo M

更新日期：1994-09-01 00:00:00

abstract：:Despite a paucity of controlled data, stereotactic pallidotomy is increasingly used for the treatment of advanced Parkinson's disease (PD). To study the efficacy of the procedure on the cardinal PD features of rigidity, tremor, bradykinesia, and postural instability, we blindly rated randomized videos of 34 patients r...

journal_title：Neurology

authors： Ondo WG,Jankovic J,Lai EC,Sankhla C,Khan M,Ben-Arie L,Schwartz K,Grossman RG,Krauss JK

更新日期：1998-01-01 00:00:00

abstract：OBJECTIVE:This study aims to evaluate protective effects of brief repetitive bilateral arm ischemic preconditioning (BAIPC) on stroke recurrence in patients with symptomatic atherosclerotic intracranial arterial stenosis (IAS). METHODS:A total of 68 consecutive cases with symptomatic IAS, diagnosed by imaging, were en...

journal_title：Neurology

authors： Meng R,Asmaro K,Meng L,Liu Y,Ma C,Xi C,Li G,Ren C,Luo Y,Ling F,Jia J,Hua Y,Wang X,Ding Y,Lo EH,Ji X

更新日期：2012-10-30 00:00:00

abstract：:Butyrylcholinesterase is implicated in the pathology of AD. Selective inhibitors increase acetylcholine and improve cognitive function in animal models. In dementia with Lewy bodies, cholinergic activities are more affected than in AD. The authors report a highly significant association between temporal cortex butyryl...

journal_title：Neurology

authors： Perry E,McKeith I,Ballard C

更新日期：2003-06-10 00:00:00

abstract：:Functional brain imaging has been a standard tool in the basic and clinical neurosciences for at least 2 decades, and structural brain imaging can claim an even longer track record of successful use for diagnosis of neurodegenerative disease. It is instructive to recall the ways in which brain imaging has been used to...

journal_title：Neurology

authors： Habeck C,Whitwell JL

更新日期：2013-01-08 00:00:00

abstract：OBJECTIVE:Brain atrophy is common in subcortical ischemic vascular disease, but the underlying mechanisms are poorly understood. We set out to examine the effects of incident subcortical infarcts on cortical morphology. METHODS:A total of 276 subjects with cerebral autosomal dominant arteriopathy with subcortical infa...

journal_title：Neurology

authors： Duering M,Righart R,Csanadi E,Jouvent E,Hervé D,Chabriat H,Dichgans M

更新日期：2012-11-13 00:00:00

abstract：:Genetic factors are important in Alzheimer disease (AD) and Parkinson disease but have not been well characterized in Lewy body dementia (LBD). The authors obtained family history in patients from an autopsy series of AD and LBD and in living healthy controls. A family history of dementia was more common in both LBD a...

journal_title：Neurology

authors： Woodruff BK,Graff-Radford NR,Ferman TJ,Dickson DW,DeLucia MW,Crook JE,Arvanitakis Z,Brassler S,Waters C,Barker W,Duara R

更新日期：2006-06-27 00:00:00

abstract：OBJECTIVES:We aimed to determine the incidence of electrographic seizures in children in the pediatric intensive care unit who underwent EEG monitoring, risk factors for electrographic seizures, and whether electrographic seizures were associated with increased odds of mortality. METHODS:Eleven sites in North America ...

journal_title：Neurology

authors： Abend NS,Arndt DH,Carpenter JL,Chapman KE,Cornett KM,Gallentine WB,Giza CC,Goldstein JL,Hahn CD,Lerner JT,Loddenkemper T,Matsumoto JH,McBain K,Nash KB,Payne E,Sánchez SM,Fernández IS,Shults J,Williams K,Yang A,Dlu

更新日期：2013-07-23 00:00:00

abstract：OBJECTIVE:To identify the level of evidence for use of nusinersen to treat spinal muscular atrophy (SMA) and review clinical considerations regarding use. METHODS:The author panel systematically reviewed nusinersen clinical trials for patients with SMA and assigned level of evidence statements based on the American Ac...

journal_title：Neurology

authors： Michelson D,Ciafaloni E,Ashwal S,Lewis E,Narayanaswami P,Oskoui M,Armstrong MJ

更新日期：2018-11-13 00:00:00

abstract：:The clinical and genetic findings are described for 16 patients from a large Italian family with a variant form of hereditary spastic paraplegia and congenital arachnoid cysts inherited as an autosomal dominant trait. A molecular study has revealed a novel missense mutation, T614I, in exon 17 of SPG4, which may play a...

journal_title：Neurology

authors： Orlacchio A,Gaudiello F,Totaro A,Floris R,St George-Hyslop PH,Bernardi G,Kawarai T

更新日期：2004-05-25 00:00:00

abstract：:Previous studies reported that a 2- to 3-week course of IV cyclophosphamide plus adrenocorticotropic hormone (ACTH) induction can temporarily halt progressive MS for a period of 12 months in the majority of patients treated, after which reprogression occurs. The Northeast Cooperative Multiple Sclerosis Treatment Group...

journal_title：Neurology

authors： Weiner HL,Mackin GA,Orav EJ,Hafler DA,Dawson DM,LaPierre Y,Herndon R,Lehrich JR,Hauser SL,Turel A

更新日期：1993-05-01 00:00:00

abstract：:Dyskinesias are usually seen in Parkinson's disease (PD) patients after several years of L-dopa therapy. Their presence has been attributed to supersensitivity of striatal D1 and D2 receptors. We have used PET to assess striatal D2 receptor binding in untreated PD patients and striatal D1 and D2 binding in L-dopa-trea...

journal_title：Neurology

authors： Turjanski N,Lees AJ,Brooks DJ

更新日期：1997-09-01 00:00:00

abstract：:Pramipexole is a new, selective, nonergoline dopamine agonist that acts on D2 and preferentially on D3 dopamine receptors. Phase II and III clinical trials have shown this drug to be useful in treating both early and advanced Parkinson's disease (PD) patients. A double-blind, randomized, multicenter study was performe...

journal_title：Neurology

authors： Guttman M

更新日期：1997-10-01 00:00:00

abstract：OBJECTIVE:Parkinson disease (PD), a devastating neurodegenerative disorder, affects motor abilities and cognition as well. It is not clear whether the proapoptotic protein, Bid, is involved in tumor necrosis factor death receptor I (TNFRI)-mediated destructive signal transduction pathways such as cell dysfunction or ne...

journal_title：Neurology

authors： Jiang H,He P,Adler CH,Shill H,Beach TG,Li R,Shen Y

更新日期：2012-10-23 00:00:00

abstract：:Methionine-enkephalin, substance P, and homovanillic acid concentrations were measured in the CSF of subjects not affected by neurologic disorders (group 1), and in parkinsonian patients who had a slight or moderate (group 2) or severe (group 3) disability. Homovanillic acid and substance P concentrations in the CSF o...

journal_title：Neurology

authors： Pezzoli G,Panerai AE,Di Giulio A,Longo A,Passerini D,Carenzi A

更新日期：1984-04-01 00:00:00

abstract：:Pure alexia, following an infarction in the distribution of the left posterior cerebral artery, is attributed to damage of the left occipital lobe and the splenium of the corpus callosum. We describe a case of pure alexia in a 57-year-old woman with infarction of the left lateral geniculate body and the splenium of th...

journal_title：Neurology

authors： Stommel EW,Friedman RJ,Reeves AG

更新日期：1991-04-01 00:00:00

abstract：OBJECTIVE:To clinically characterize the temporal relationship between dyskinesia and the antiparkinsonian response when dyskinesia first emerges during long-term levodopa therapy and to determine if it is consistent with the hypothesized mechanism by which dyskinesia develops. METHODS:Dyskinesia and the antiparkinson...

journal_title：Neurology

authors： Nutt JG,Chung KA,Holford NH

更新日期：2010-04-13 00:00:00

abstract：:We established the frequency of Horner's syndrome (HS) in 248 elective patients after coronary artery bypass surgery. Patients were evaluated neurologically pre- and post-operatively and 6 months after surgery. Nineteen patients (7.7%) developed unilateral HS postoperatively, 12 involving the left eye. The finding per...

journal_title：Neurology

authors： Barbut D,Gold JP,Heinemann MH,Hinton RB,Trifiletti RR

更新日期：1996-01-01 00:00:00

abstract：OBJECTIVE:Physician prediction of outcome in critically ill neurologic patients impacts treatment decisions and goals of care. In this observational study, we prospectively compared predictions by neurointensivists to patient outcomes at 6 months. METHODS:Consecutive neurologic patients requiring mechanical ventilatio...

journal_title：Neurology

authors： Finley Caulfield A,Gabler L,Lansberg MG,Eyngorn I,Mlynash M,Buckwalter MS,Venkatasubramanian C,Wijman CA

更新日期：2010-04-06 00:00:00

abstract：:As there is currently no standardized assessment tool for evaluating Parkinson disease (PD) patients for deep brain stimulation (DBS), the authors developed the Florida Surgical Questionnaire for Parkinson Disease (FLASQ-PD). Part I of the study was a retrospective analysis of 174 patients presenting for a surgical sc...

journal_title：Neurology

authors： Okun MS,Fernandez HH,Pedraza O,Misra M,Lyons KE,Pahwa R,Tarsy D,Scollins L,Corapi K,Friehs GM,Grace J,Romrell J,Foote KD

更新日期：2004-07-13 00:00:00

abstract：:In 41 cases of verified ruptured saccular aneurysm, we prospectively predicted the presence or absence of delayed symptomatic cerebral vasospasm. CT criteria quantifying the extent and location of subarachnoid blood (developed in our previous retrospective study) were used in this prospective series of patients. Twent...

journal_title：Neurology

authors： Kistler JP,Crowell RM,Davis KR,Heros R,Ojemann RG,Zervas T,Fisher CM

更新日期：1983-04-01 00:00:00

abstract：:In children, seizures associated with status epilepticus (SE) include a number of types that are age-related. These types of seizures are not associated with SE in older patients. Likewise, etiologies of SE in children are also unique to this patient population, in particular those responsible for SE in the neonate. C...

journal_title：Neurology

authors： Lockman LA

更新日期：1990-05-01 00:00:00