Abstract:
Importance:Postpartum hemorrhage (PPH) remains a major cause of maternal mortality worldwide, occurring in both vaginal and cesarean deliveries. We have witnessed improvements in both prevention and treatment of PPH. Tranexamic acid (TXA) has been investigated as a potential adjunct therapy to uterotonics within this setting. Objective:The aim of this article is to summarize existing recommendations on the use of TXA in obstetrics and review current data on clinical outcomes after TXA use. Evidence Acquisition:We reviewed guidelines from a number of professional societies and performed an extensive literature search reviewing relevant and current data in this area. Results and Conclusions:In the prevention of PPH, TXA use before both vaginal and cesarean deliveries reduces the amount of postpartum blood loss and should be considered in patients at higher risk for hemorrhage. In the treatment of PPH, TXA should be initiated early for maximal survival benefit from hemorrhage, and it provides no additional benefit if administered more than 3 hours from delivery. Overall, current evidence assessing the risks of TXA use in an obstetric population is reassuring.
journal_name
Obstet Gynecol Survjournal_title
Obstetrical & gynecological surveyauthors
Ahmadzia HK,Phillips JM,Katler QS,James AHdoi
10.1097/OGX.0000000000000597subject
Has Abstractpub_date
2018-10-01 00:00:00pages
587-594issue
10eissn
0029-7828issn
1533-9866journal_volume
73pub_type
杂志文章,评审abstract::Mature cystic teratomas (MCT), commonly called dermoid cysts, are the most common benign germ cell tumors of the ovary in women of reproductive age. Future fertility is of major concern among these women; therefore, the surgical management must focus on preserving ovarian tissue and minimizing adhesion formation. Pati...
journal_title:Obstetrical & gynecological survey
pub_type: 杂志文章,评审
doi:10.1097/00006254-200012000-00004
更新日期:2000-12-01 00:00:00
abstract::Endometriosis is a common gynecological disorder with varied symptomatology including chronic pelvic pain, dysmenorrhea, and infertility. The association of endometriosis and infertility has been recognized for years, although definite evidence of causality still eludes us. In this review, we will explore three genera...
journal_title:Obstetrical & gynecological survey
pub_type: 杂志文章,评审
doi:10.1097/00006254-199706000-00021
更新日期:1997-06-01 00:00:00
abstract:UNLABELLED:Congenital cytomegalovirus (CMV) is the most common intrauterine infection and the leading infectious cause of sensorineural hearing loss and mental retardation. This article reviews the issues that relate to the diagnosis and management of this disease, detailing the points that led to the recent published ...
journal_title:Obstetrical & gynecological survey
pub_type: 杂志文章,评审
doi:10.1097/OGX.0b013e31821102b4
更新日期:2010-11-01 00:00:00
abstract::About 45% of all pregnant women and 25% of all women postpartum suffer from pelvic girdle pain and/or low back pain (PLPP). It has been suggested that increased motion of the three joints in the pelvic ring is one of the causes of PLPP. However, in spite of the availability of high technology the relation between enla...
journal_title:Obstetrical & gynecological survey
pub_type: 杂志文章,评审
doi:10.1097/OGX.0b013e3181950f1b
更新日期:2009-03-01 00:00:00
abstract::Quinolones and fluoroquinolones are highly efficient antibiotics. However, concerns regarding possible harmful effects have limited their use during pregnancy. Nevertheless, accumulating clinical data suggest that they may be safe during pregnancy. This review aimed to explore the mechanisms of action of the quinolone...
journal_title:Obstetrical & gynecological survey
pub_type: 杂志文章,评审
doi:10.1097/OGX.0000000000000122
更新日期:2014-11-01 00:00:00
abstract::This article reviews the literature that evaluates pruritic urticarial papules and plaques of pregnancy, herpes gestationis, and intrahepatic cholestasis of pregnancy and their impact on the fetus. Using MEDLINE years 1966 to 1999, a literature search was performed using the terms pregnancy, dermatology, pruritic urti...
journal_title:Obstetrical & gynecological survey
pub_type: 杂志文章,评审
doi:10.1097/00006254-200107000-00022
更新日期:2001-07-01 00:00:00
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journal_title:Obstetrical & gynecological survey
pub_type: 杂志文章,评审
doi:10.1097/01.OGX.0000097781.79401.0B
更新日期:2003-12-01 00:00:00
abstract::The pregnant woman is susceptible to a variety of respiratory complications. When a pregnant patient presents with an abnormal chest x-ray or a pulmonary complaint, an understanding of the pathophysiology of pregnancy will guide the clinician in establishing a diagnosis. Pregnancy brings about many changes to a woman'...
journal_title:Obstetrical & gynecological survey
pub_type: 杂志文章,评审
doi:10.1097/00006254-200201000-00022
更新日期:2002-01-01 00:00:00
abstract:UNLABELLED:To assess the impact of dengue infection during pregnancy on birth outcomes, we conducted a systematic review of 30 published studies (19 case reports, 9 case series, and 2 comparison studies). Studies were identified by searching computerized databases using dengue and dengue hemorrhagic fever, cross-refere...
journal_title:Obstetrical & gynecological survey
pub_type: 杂志文章,评审
doi:10.1097/OGX.0b013e3181cb8fbc
更新日期:2010-02-01 00:00:00
abstract:UNLABELLED:Pregnancy is a hypercoagulable state that increases the risk of thromboembolic events. These risks may be further increased in the presence of an acquired or inherited thrombophilia. Thrombophilias have been associated with both maternal and fetal complications. The use of anticoagulants during pregnancy may...
journal_title:Obstetrical & gynecological survey
pub_type: 杂志文章,评审
doi:10.1097/01.ogx.0000193878.57208.ad
更新日期:2006-01-01 00:00:00
abstract:UNLABELLED:Depression is common in reproductive age women, and continued pharmacologic treatment of depression during pregnancy may be necessary to prevent relapse, which could be harmful for both the fetus and the mother. Although data on drug safety are imperfect and incomplete, the benefits of antidepressant therapy...
journal_title:Obstetrical & gynecological survey
pub_type: 杂志文章,评审
doi:10.1097/OGX.0b013e3181676be8
更新日期:2008-04-01 00:00:00
abstract:INTRODUCTION:Pregnancy is a critical period of body weight regulation. Maternal obesity and excessive gestational weight gain have become increasingly common and contribute to poor obstetrical outcomes for mother and baby. Regular participation in physical activity may improve risk profiles in pregnant women. PURPOSE ...
journal_title:Obstetrical & gynecological survey
pub_type: 杂志文章,评审
doi:10.1097/OGX.0b013e318242030e
更新日期:2012-02-01 00:00:00
abstract:UNLABELLED:Among those facing infertility in the United States, underinsured and uninsured women are at the greatest disadvantage. Women who receive medical care under Medicaid are rarely covered for infertility testing; only 4 states will cover infertility treatment as an element of family planning and preconception c...
journal_title:Obstetrical & gynecological survey
pub_type: 杂志文章,评审
doi:10.1097/OGX.0b013e318286f780
更新日期:2013-04-01 00:00:00
abstract:UNLABELLED:Primary pure ovarian leiomyosarcomas constitute a malignant subgroup of ovarian smooth muscle tumors which comprise only 1% of ovarian tumors. Their origin, etiology, histologic features, clinical behavior, and optimal treatment are still obscure. Malignant behavior is almost always associated with any 2 of ...
journal_title:Obstetrical & gynecological survey
pub_type: 杂志文章,评审
doi:10.1097/01.ogx.0000268629.16151.71
更新日期:2007-07-01 00:00:00
abstract:Importance:Uterine torsion is an uncommon but life-threatening clinical situation that requires a high index of suspicion for diagnosis. Objective:The aim of this study was to review literature and determine the etiology, presentation, diagnosis, and management of uterine torsion in the gravid and nongravid patients. ...
journal_title:Obstetrical & gynecological survey
pub_type: 杂志文章,评审
doi:10.1097/OGX.0000000000000767
更新日期:2020-04-01 00:00:00
abstract:UNLABELLED:A systematic literature review was performed to determine whether leiomyomata are associated with decreased fertility rates, and whether surgical removal increases fertility rates postoperatively. Meta-analysis was conducted when multiple studies addressed a single issue and were sufficiently homogeneous. Da...
journal_title:Obstetrical & gynecological survey
pub_type: 杂志文章,评审
doi:10.1097/00006254-200108000-00022
更新日期:2001-08-01 00:00:00
abstract:Importance:Real-time electrohysterography (EHG)-based technologies have recently become available for uterine monitoring during term labor. Therefore, obstetricians need to be familiar with the diagnostic value, advantages, and limitations of using EHG. Objective:The aims of this study were to determine the diagnostic...
journal_title:Obstetrical & gynecological survey
pub_type: 杂志文章,评审
doi:10.1097/OGX.0000000000000560
更新日期:2018-05-01 00:00:00
abstract:UNLABELLED:Insulinomas are rare tumors with an incidence of approximately four cases per million person-years. Nineteen cases of insulinoma during pregnancy have been reported. Hypoglycemic symptoms usually appear during the first trimester. A 28-year-old primigravida was admitted at 6 weeks of gestation after referral...
journal_title:Obstetrical & gynecological survey
pub_type: 杂志文章,评审
doi:10.1097/00006254-200204000-00022
更新日期:2002-04-01 00:00:00
abstract::The assessment of osteoporosis risk factors can help guide early intervention. The objective of this study was to analyze numerous potential risk factors to see which were associated with postmenopausal osteoporosis. Women aged 49 or greater presenting for dual-energy x-ray absorptiometry bone scans were recruited fro...
journal_title:Obstetrical & gynecological survey
pub_type: 杂志文章,评审
doi:10.1097/OGX.0b013e3181fc6d30
更新日期:2010-09-01 00:00:00
abstract:UNLABELLED:Urolithiasis complicates up to one in every 200 pregnancies; consequently, the practicing obstetrician should be aware of the symptoms of urolithiasis, the diagnostic procedures available for its diagnosis, and their associated risks. These include ultrasound, urography, and magnetic resonance imaging. Diagn...
journal_title:Obstetrical & gynecological survey
pub_type: 杂志文章,评审
doi:10.1097/01.ogx.0000243773.05916.7a
更新日期:2006-11-01 00:00:00
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journal_title:Obstetrical & gynecological survey
pub_type: 杂志文章,meta分析
doi:10.1097/00006254-199809000-00025
更新日期:1998-09-01 00:00:00
abstract::Brain abscess is a potentially life-threatening complication that is only rarely associated with pregnancy. Although predispositions such as a preexisting infection, foreign body, or immunosuppression are often present, up to 30% of individuals could have no risk factors. Presenting symptoms are often nonspecific but ...
journal_title:Obstetrical & gynecological survey
pub_type: 杂志文章,评审
doi:10.1097/01.ogx.0000115861.54002.8b
更新日期:2004-03-01 00:00:00
abstract::Arthropod-borne bacterial diseases affect more than 25,000 Americans every year and thousands more around the world. These infections present a diagnostic dilemma for clinicians because they mimic many other pathologic conditions and are often low on or absent from the differential diagnosis list. Diagnosis is particu...
journal_title:Obstetrical & gynecological survey
pub_type: 杂志文章,评审
doi:10.1097/OGX.0b013e3182a5ed46
更新日期:2013-09-01 00:00:00
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journal_title:Obstetrical & gynecological survey
pub_type: 杂志文章,评审
doi:10.1097/01.ogx.0000219564.65999.0d
更新日期:2006-07-01 00:00:00
abstract:UNLABELLED:Thromboembolism in pregnancy is a major contributor to pregnancy morbidity and mortality with potentially serious adverse effects for both mother and fetus. The purposes of this article are to explore the impact of heritable and acquired thrombophilias on pregnancy and to determine the appropriateness of scr...
journal_title:Obstetrical & gynecological survey
pub_type: 杂志文章,评审
doi:10.1097/01.ogx.0000165116.96026.4e
更新日期:2005-06-01 00:00:00
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journal_title:Obstetrical & gynecological survey
pub_type: 杂志文章,评审
doi:10.1097/00006254-197907010-00029
更新日期:1979-07-01 00:00:00
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journal_title:Obstetrical & gynecological survey
pub_type: 杂志文章,评审
doi:10.1097/00006254-199010000-00001
更新日期:1990-10-01 00:00:00
abstract:Importance:Preconception care (PCC) has the potential to optimize pregnancy outcomes. However, awareness of PCC among the target population is generally limited, and the use of PCC remains low. Importance:The objective of this study was to review the literature on women's perceptions regarding barriers and facilitator...
journal_title:Obstetrical & gynecological survey
pub_type: 杂志文章,评审
doi:10.1097/OGX.0000000000000360
更新日期:2016-10-01 00:00:00
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journal_title:Obstetrical & gynecological survey
pub_type: 杂志文章,评审
doi:
更新日期:1990-03-01 00:00:00
abstract::The various phenomena of toxemia of pregnancy both in primiparous and multiparous women may be explained by postulating a defect in the calcium transport mechanism, both in the smooth muscle of the uterus and vascular smooth muscle as well as a similar defect in platelets. The involvement of prostaglandin E has not be...
journal_title:Obstetrical & gynecological survey
pub_type: 杂志文章
doi:10.1097/00006254-198005000-00028
更新日期:1980-05-01 00:00:00