Abstract:
:Photo-receptors are widely present in both prokaryotic and eukaryotic cells, which serves as the foundation of tuning cell behaviors with light. While practices in eukaryotic cells have been relatively established, trials in bacterial cells have only been emerging in the past few years. A number of light sensors have been engineered in bacteria cells and most of them fall into the categories of two-component and one-component systems. Such a sensor toolbox has enabled practices in controlling synthetic circuits at the level of transcription and protein activity which is a major topic in synthetic biology, according to the central dogma. Additionally, engineered light sensors and practices of tuning synthetic circuits have served as a foundation for achieving light based real-time feedback control. Here, we review programming bacteria cells with light, introducing engineered light sensors in bacteria and their applications, including tuning synthetic circuits and achieving feedback controls over microbial cell culture.
journal_name
Front Microbioljournal_title
Frontiers in microbiologyauthors
Liu Z,Zhang J,Jin J,Geng Z,Qi Q,Liang Qdoi
10.3389/fmicb.2018.02692subject
Has Abstractpub_date
2018-11-08 00:00:00pages
2692issn
1664-302Xjournal_volume
9pub_type
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