Abstract：
INTRODUCTION:The aim of our study was to compare the features at diagnosis in patients with ornithosis to patients with avian acute hypersensitivity pneumonitis (HP). Clinical, biological and radiological differences could potentially help clinicians to distinguish these diseases. METHODS:We conducted a retrospective study on patients admitted from 2000 to 2016 in three hospitals. Ornithosis was diagnosed based on a positive polymerase chain reaction for Chlamydophila psittaci on respiratory samples and/or a seroconversion while HP was diagnosed on the basis of at least one positive serum precipitin. RESULTS:Twelve patients with HP and 13 patients with ornithosis were identified. Compared to HP, ornithosis occurred more frequently in males (P=0.047), with less previous respiratory diseases (P=0.01), shorter symptom duration (P=0.03), less frequently bilateral crackles (P=0.004), more severe disease requiring more frequently intensive care admission (P=0.005), higher CRP values (P=0.005) and more profound lymphopenia (P=0.02). Ground glass shadowing on CT scan (P=0.001) or bronchiectasis (P=0.03) were more frequently noted in patients with HP. CONCLUSIONS:Our results suggest that patients with ornithosis and HP have important differences in their clinical, biological, and radiological presentation.
journal_name
Rev Mal Respirjournal_title
Revue des maladies respiratoiresauthors
Jézéquel A,Jouneau S,Bouju P,Letheulle J,Kerjouan M,Gacouin Adoi
10.1016/j.rmr.2017.11.013subject
Has Abstractpub_date
2019-03-01 00:00:00pages
298-306issue
3eissn
0761-8425issn
1776-2588pii
S0761-8425(18)30340-1journal_volume
36pub_type
杂志文章abstract：INTRODUCTION:The EOLE cohort aimed to describe, in routine clinical practice, the characteristics and management of patients receiving bevacizumab in combination with first-line metastatic chemotherapy for advanced metastatic or recurrent non squamous non-small cell lung cancer (nsNSCLC), as well as its efficacy and sa...
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