Muse Cell: A New Paradigm for Cell Therapy and Regenerative Homeostasis in Ischemic Stroke.

Abstract:

:Multilineage-differentiating stress enduring (Muse) cells are one of the most promising donor cells for cell therapy against ischemic stroke, because they can differentiate into any type of cells constructing the central nervous system (CNS), including the neurons. They can easily be isolated from the bone marrow stromal cells (BMSCs), which may also contribute to functional recovery after ischemic stroke as donor cells. In this chapter, we concisely review their biological features and then future perspective of Muse cell transplantation for ischemic stroke. In addition, we briefly refer to the surprising role of Muse cells to maintain the homeostasis in the living body under both physiological and pathological conditions.

journal_name

Adv Exp Med Biol

authors

Kuroda S,Koh M,Hori E,Hayakawa Y,Akai T

doi

10.1007/978-4-431-56847-6_10

subject

Has Abstract

pub_date

2018-01-01 00:00:00

pages

187-198

eissn

0065-2598

issn

2214-8019

journal_volume

1103

pub_type

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