FDG PET/CT as a survival prognostic factor in patients with advanced renal cell carcinoma.

abstract：:B-cell chronic lymphocytic leukemia (B-CLL) is one of the most common leukemias among the elderly and, despite many efforts, still stays incurable. Recent studies point to the microenvironment as the critical factor providing leukemic lymphocytes with pro-survival signals. Thus, the neighboring cells appear to be a pe...

journal_title：Clinical and experimental medicine

authors： Filip AA,Ciseł B,Wąsik-Szczepanek E

更新日期：2015-02-01 00:00:00

abstract：:Cancer stem cells (CSCs) are thought to be a major player in tumor initiation, progression, and metastasis. Targeting CSCs for elimination presents a promising therapeutic strategy; however, this approach will require a stronger understanding of CSC biology and identification of CSC-specific markers. The present study...

journal_title：Clinical and experimental medicine

authors： Razi S,Sadeghi A,Asadi-Lari Z,Tam KJ,Kalantari E,Madjd Z

更新日期：2020-09-23 00:00:00

abstract：:Gastrointestinal (GIT) cancers represent the third common cancers worldwide, characterized by rapid progression and higher mortality rate. Matrix metalloproteinases (MMPs) play an important role in cancer metastases. The present study was conducted to estimate and evaluate the role of MMP-7, -9, -10 and -12 and TGF β1...

journal_title：Clinical and experimental medicine

authors： El-Ashmawy NE,Khedr NF,Mansour MG,Al-Ashmawy GM

更新日期：2020-11-01 00:00:00

abstract：:Pancreatic cancer (PC) is a leading cause of cancer death worldwide, especially in Western societies. Its aggressive nature and poor prognosis increase the need for identifying new and more accurate diagnostic and prognostic tools. We studied 41 patients who had undergone radical surgical resection for PC, investigate...

journal_title：Clinical and experimental medicine

authors： Tsiaousidou A,Tsaroucha AK,Lambropoulou M,Pitiakoudis M,Polychronidis A,Chatzitheoklitos E,Romanidis K,Simopoulos C

更新日期：2016-08-01 00:00:00

abstract：:Diabetes is one of the most common and challenging health problems. Studies in several nations show that polymorphisms within the transcription factor 7-like 2 genes could be associated with type 2 diabetes (T2D). Therefore, a case-control study was conducted to find the association between SNP rs7903146 and T2D in ou...

journal_title：Clinical and experimental medicine

authors： Palizban A,Nikpour M,Salehi R,Maracy MR

更新日期：2012-06-01 00:00:00

abstract：:Systemic lupus erythematosus (SLE) is the prototype autoimmune rheumatic disease. The etiology of this disease is incompletely understood; however, environmental factors and genetic predisposition are involved. Cytokine-mediated immunity plays a crucial role in the pathogenesis of SLE. We investigate the association o...

journal_title：Clinical and experimental medicine

authors： Palafox-Sánchez CA,Oregon-Romero E,Salazar-Camarena DC,Valle YM,Machado-Contreras JR,Cruz A,Orozco-López M,Orozco-Barocio G,Vázquez-Del Mercado M,Muñoz-Valle JF

更新日期：2015-11-01 00:00:00

abstract：:An in vitro skin explant model was originally developed to predict the occurrence and severity of acute graft-versus-host disease in allogeneic hematopoietic stem cell transplants. In previous studies we reported that peripheral blood mononuclear cells of patients with rheumatoid arthritis were able to induce graft-ve...

journal_title：Clinical and experimental medicine

authors： Stechová K,Vavrincová P,Reitzová H,Chudoba D,Zimák J,Hromadníková I

更新日期：2001-06-01 00:00:00

abstract：:Previous studies have implicated protective effects of vitamin D on insulin secretion and pancreas beta cell function. The goal of the present study is to determine if a combination therapy of 25-hydroxyvitamin D3 and insulin had any advantage over insulin therapy alone on lipid peroxidation and antioxidant activity i...

journal_title：Clinical and experimental medicine

authors： Noyan T,Balaharoğlu R,Kömüroğlu U

更新日期：2005-05-01 00:00:00

abstract：:Mixed-phenotype acute leukemia (MPAL) is the infrequent type of acute leukemia characterized by immunophenotypic and/or cytochemical features of both lineages, but the diagnosis of this disease still is a challenge. In this study, we analyzed immunophenotyping, cytochemistry and frequency of MPAL patients to better di...

journal_title：Clinical and experimental medicine

authors： Poopak B,Khosravi A,Bahoush-Mehdiabadi G,Madani T,Khodadi E,Farahani Z,Vahedi AA,Khosravipour G,Poopak P,Poopak AH

更新日期：2018-11-01 00:00:00

abstract：:The predominance of the effector mechanisms by CD4 + T cells is a characteristic of inflammatory autoimmune diseases such as rheumatoid arthritis (RA). The CD40/CD40L costimulatory pathway contributes to these pathogenic mechanisms by promoting autoantibody production and inflammation. Aberrant expression of CD40 and ...

journal_title：Clinical and experimental medicine

authors： Román-Fernández IV,García-Chagollán M,Cerpa-Cruz S,Jave-Suárez LF,Palafox-Sánchez CA,García-Arellano S,Sánchez-Zuno GA,Muñoz-Valle JF

更新日期：2019-11-01 00:00:00

abstract：:Behcet's disease is a recurrent multisystem vasculitis that can affect any organ or system, but was originally described as orogenital ulcerations and uveitis. Specific criteria have been proposed for diagnosis and identification of affected organs by different national authorities. Behcet's disease is proposed to be ...

journal_title：Clinical and experimental medicine

authors： Al-Mutawa SA,Hegab SM

更新日期：2004-12-01 00:00:00

abstract：:To investigate the expression of cyclin G1, cyclin G2 in nasopharyngeal carcinoma (NPC) cell lines and its significance. The protein expression of cyclin G1, cyclin G2 in NPC cell lines of different differentiation degree (HNE2, CNE1) was detected by indirect immunofluorescence. The mRNA expression of cyclin G1, cycli...

journal_title：Clinical and experimental medicine

authors： Ye XX,Liu CB,Chen JY,Tao BH,Zhi-Yi C

更新日期：2012-03-01 00:00:00

abstract：:The effect of preimmunisation with cancer procoagulant (CP) on the growth of Walker 256 carcinosarcoma cells in Wistar Lew/Han/IMP rats in vivo has been analysed. One group of rats was immunised with CP purified from human amnion-chorion membranes. The rest of the animals (control groups) were injected with 0.9% NaCl ...

journal_title：Clinical and experimental medicine

authors： Kamocka M,Kaplinska K,Mielicki WP

更新日期：2006-10-01 00:00:00

abstract：:To evaluate potency and safety of 14-day bismuth-furazolidone quadruple regimens and to compare efficacies of five proton pump inhibitors (PPIs) for the initial eradication of Helicobacter pylori (H. pylori), 175 eligible patients were enrolled and randomly assigned to 14-day quadruple regimens consisting of bismuth (...

journal_title：Clinical and experimental medicine

authors： Chen L,He J,Wang L,Ge Q,Chu H,Chen Y,Chen X,Long Y,Deng Y,He H,Li A,Chen S

更新日期：2018-11-01 00:00:00

abstract：:Mesenchymal stem cells (MSCs) have captured the attention of researchers today due to their multipotent differentiation capacity. Also, they have been successfully applied clinically, in the treatment of various diseases of the heart and musculoskeletal systems, with encouraging results. Their supportive role in haema...

journal_title：Clinical and experimental medicine

authors： Wong RS,Cheong SK

更新日期：2014-08-01 00:00:00

abstract：:Staphylococcus aureus (S. aureus) is the most common bacterium in sepsis and pneumonia involving gram-positive bacteria. Lipoteichoic acid (LTA) is a cell wall component of gram-positive bacteria. It is a potent inducer of inflammatory mediators in human dendritic cells, human pulmonary epithelial cells, and murine ma...

journal_title：Clinical and experimental medicine

authors： Wu BQ,Luo JM,Wang YH,Shi YF,Liu H,Ba JH,Zhang TT

更新日期：2014-05-01 00:00:00

abstract：:To investigate lncRNAs acting as competing endogenous RNAs (ceRNAs) involved in oncogenesis and progression of HCC. Different expressed lncRNAs, microRNAs, and mRNAs (DElncRNAs, DEmiRNAs, DEmRNAs), downloaded from The Cancer Genome Atlas (TCGA) database, were identified by edgeR package. CeRNA network was constructed ...

journal_title：Clinical and experimental medicine

authors： Qu L,Cai X,Xu J,Wei X,Qu X,Sun L,Gong L,Su C,Zhu Y

更新日期：2020-08-01 00:00:00

abstract：:Triglyceride-rich lipoproteins contain both apolipoproteins E (ApoE) and C-III (ApoC-III), which show opposite functional properties. The relationships between the ApoE (epsilon2/epsilon3/epsilon4) gene polymorphism and ApoC-III/ApoE ratio has never been investigated. A large population (n=552) of cardiovascular patie...

journal_title：Clinical and experimental medicine

authors： Olivieri O,Martinelli N,Bassi A,Trabetti E,Girelli D,Pizzolo F,Friso S,Pignatti PF,Corrocher R

更新日期：2007-12-01 00:00:00

abstract：:Apoptosis of the acinar and ductal epithelial cells of the salivary glands has been proposed as a mechanism possibly responsible for the impairment of the secretory function in Sjögren's syndrome, an organ-specific autoimmune disorder characterized by destruction of these glandular structures. The presence of serum au...

journal_title：Clinical and experimental medicine

authors： Lisi S,Sisto M,Lofrumento D,Frassanito MA,Caprio S,Romano ML,Mitolo V,D'Amore M

更新日期：2010-09-01 00:00:00

abstract：:Takayasu arteritis (TAK) is a rare granulomatous vasculitis of unknown etiology that mainly affects the aorta and its major branches. The aim is to describe the clinical features, diagnostic procedures, pathogenesis, and management of TAK in a longitudinal cohort of patients recruited within a single region of souther...

journal_title：Clinical and experimental medicine

authors： Dammacco F,Cirulli A,Simeone A,Leone P,Pulli R,Angiletta D,Rubini G,Di Palo A,Vacca A,Dammacco R

更新日期：2020-10-07 00:00:00

abstract：:Recently, it was discovered that high mobility group box chromosomal protein 1 (HMGB1) acts as a potent pro-inflammatory cytokine that is released into the extracellular milieu. Signal transducer and activator of transcription (STAT) proteins play an important role in cytokine signaling. Some investigators have report...

journal_title：Clinical and experimental medicine

authors： Guo HF,Liu SX,Zhang YJ,Liu QJ,Hao J,Gao LX

更新日期：2011-06-01 00:00:00

abstract：:Severe combined immunodeficiencies (SCID) comprise a spectrum of genetic defects that involve both humoral and cellular immunities. Defects in recombinating activating gene 1 (RAG1), RAG2, Artemis, or LIG4 can disrupt V(D)J recombination. Defective V(D)J recombination of the T and B cell receptors is responsible for T...

journal_title：Clinical and experimental medicine

authors： Karaca NE,Aksu G,Genel F,Gulez N,Can S,Aydinok Y,Aksoylar S,Karaca E,Altuglu I,Kutukculer N

更新日期：2009-12-01 00:00:00

abstract：:Interleukin-17A plays a role in tissue inflammation by inducing release of proinflammatory and neutrophil-mobilizing cytokines. We investigated the association between ulcerative colitis (UC) and polymorphisms of IL17A, rs2275913 (-197 G > A), and rs3748067 (*1249 C > T). The study was performed in 475 healthy subject...

journal_title：Clinical and experimental medicine

authors： Hayashi R,Tahara T,Shiroeda H,Saito T,Nakamura M,Tsutsumi M,Shibata T,Arisawa T

更新日期：2013-11-01 00:00:00

abstract：:Recent findings suggest that cell and gene transplantation in the infarcted myocardium may improve heart function. The aim of the study was to investigate the mechanism involved in improving heart function following the co-injection of adipose-derived stem cells (ADSCs) and basic fibroblast growth factor (bFGF) in a r...

journal_title：Clinical and experimental medicine

authors： Wang B,Ma X,Zhao L,Zhou X,Ma Y,Sun H,Yang Y,Chen B

更新日期：2016-11-01 00:00:00

abstract：:The thrombin generation potential is an in vitro measure for the capacity of an individual to generate thrombin and recognized as a reflection of a hypo- or hypercoagulable status. Measurement of the in vivo thrombin activity, however, may be of clinical significance. We evaluated a new assay for in vivo thrombin acti...

journal_title：Clinical and experimental medicine

authors： Königsbrügge O,Koder S,Riedl J,Panzer S,Pabinger I,Ay C

更新日期：2017-05-01 00:00:00

abstract：:Catastrophic antiphospholipid syndrome (CAPS) is a rare disorder, characterized by the development of multiple vascular thrombosis over a short period of time, in patients with persistently detectable antiphospholipid antibodies (aPLs). The vascular occlusions predominantly affect small vessels. The overall mortality ...

journal_title：Clinical and experimental medicine

authors： Tinti MG,Carnevale V,Inglese M,Molinaro F,Bernal M,Migliore A,De Cata A

更新日期：2019-08-01 00:00:00

abstract：:Slit2 glycoprotein has been described to regulate the inflammatory response and be involved in autoimmune diseases. Here, we investigated the expression of Slit2 and its potential significance in systemic lupus erythematosus (SLE). A total of 103 patients with SLE participated in our study. The levels of serum Slit2 w...

journal_title：Clinical and experimental medicine

authors： Zhang Y,Hu L,Li X,Chen L,Yang X

更新日期：2020-10-20 00:00:00

abstract：:Nasopharyngeal carcinoma (NPC) is a very common head and neck cancer in southern china. Despite advances in surgical and chemotherapeutic approaches, its prognosis is still not promising. Hedgehog signaling pathway was reported to be involved in a number of cancers including head and neck. However, it remains unclear ...

journal_title：Clinical and experimental medicine

authors： Yue Y,Zhong W,Pei G,Xiao B,Zhang G,Jiang F,Zhang J,Chen C,Yang P,Dang H,Chang H

更新日期：2013-11-01 00:00:00

abstract：:Atopic dermatitis (AD) is a chronic, inflammatory skin disease which is characterized by severe pruritus and affects patients' quality of life. In recent years gamma interferon (IFN-gamma) has been accepted as a novel treatment for severe AD, however, its mechanism of action is not clearly identified. Present study ev...

journal_title：Clinical and experimental medicine

authors： Panahi Y,Davoudi SM,Madanchi N,Abolhasani E

更新日期：2012-12-01 00:00:00

abstract：:Imatinib mesylate represents the first of a new generation of molecularly targeted therapies engineered to disrupt signal transduction pathways. It is a tyrosine kinase inhibitor with relatively selective activity against the Abelson (ABL) proto-oncogene, platelet-derived growth factor receptor, and c-KIT receptor. De...

journal_title：Clinical and experimental medicine

authors： Peggs K

更新日期：2004-09-01 00:00:00