Nasal Morbidity and Quality of Life After Endoscopic Transsphenoidal Surgery: A Single-Center Prospective Study.


OBJECTIVE:The aim of this study was to assess nasal morbidity of endoscopic transsphenoidal approaches (ETAs) for treatment of sellar and parasellar diseases through evaluation of quality of life (QoL) and nasal function. The impact of different ETAs, according to extent and reconstruction technique, was also studied. METHODS:Patients undergoing ETA for treatment of sellar or parasellar lesions were prospectively recruited and examined preoperatively and at 6 months after surgery according to the following workup: nasal endoscopy, rhinomanometry, acoustic rhinometry, University of Pennsylvania Smell Identification Test, Anterior Skull Base Nasal Inventory-12, Sino-nasal Outcome Test-22, and Short-Form Health Survey-36 (SF-36). RESULTS:Of 34 patients initially recruited, 29 completed follow-up examinations. Seven patients (24.14%) developed turbinoseptal synechiae; anterior septal perforations were observed in 3 patients (10.35%). More extended surgical dissection was associated with the presence of postoperative septal perforation and synechiae. No significant difference was noted between preoperative and postoperative results on the University of Pennsylvania Smell Identification Test, acoustic rhinometry, Sino-nasal Outcome Test-22, or Anterior Skull Base Nasal Inventory-12. There was a significant increase in nasal airflow after surgery and improvement of the Short-Form Health Survey-36 score in 4 of 8 domains. CONCLUSIONS:The modular ETA technique is associated with minimal morbidity and preserves nasal patency, airflow, and olfactory function. Quality of life is not affected and although small septal perforations and synechiae can be observed, nasal physiology is not compromised. Nonetheless, careful manipulation of sinonasal structures is recommended to minimize postoperative sequelae.


World Neurosurg


World neurosurgery


Schreiber A,Bertazzoni G,Ferrari M,Rampinelli V,Verri P,Mattavelli D,Fontanella M,Nicolai P,Doglietto F




Has Abstract


2019-03-01 00:00:00












  • Giant Sacral Schwannoma Causing Bilateral Hydronephrosis: Case Report and Review of the Literature.

    abstract:BACKGROUND:Giant sacral schwannomas are very rare, and less than 1%-5% of spinal schwannomas are found in the sacral region. These frequently grow to considerable size because of permissive anatomic location and benign, slow growth of tumor. They can be unnoticed before reaching a huge size. CASE DESCRIPTION:We report...

    journal_title:World neurosurgery

    pub_type: 杂志文章,评审


    authors: Tahta A,Dinc C,Ozdenkaya Y,Cakir A

    更新日期:2020-10-01 00:00:00

  • Hippocampal Transection Plus Tumor Resection as a Novel Surgical Treatment for Temporal Lobe Epilepsy Associated with Cerebral Cavernous Malformations.

    abstract:OBJECTIVE:The optimal surgical treatment for cavernous malformation-related temporal lobe epilepsy (CRTLE) is still controversial because it frequently involves the hippocampus as an epileptogenic zone. Here we describe our unique surgical strategy of performing hippocampal transection (HT) plus tumor resection for CRT...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Ishida W,Morino M,Matsumoto T,Casaos J,Ramhmdani S,Lo SL

    更新日期:2018-11-01 00:00:00

  • Visual complications after stent-assisted endovascular embolization of paraophthalmic and suprasellar variant superior hypophyseal aneurysms: the Duke Cerebrovascular Center experience in 57 patients.

    abstract:OBJECTIVE:To review retrospectively experience with stent-assisted coiling of ophthalmic segment internal carotid artery (ICA) aneurysms to report outcome data and identify the rate of associated visual complications. METHODS:The Duke endovascular database was retrospectively reviewed to identify all ICA aneurysms tre...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Ferrell AS,Lessne ML,Alexander MJ,Shah P,Golshani K,Zomorodi A,Smith TP,Britz GW

    更新日期:2012-09-01 00:00:00

  • Affinity of Mucormycosis for Basal Ganglia in Intravenous Drug Users: Case Illustration and Review of Literature.

    abstract::Central nervous system mucormycosis is an aggressive fungal infection often ending in fatality. The usual circumstance is an immunocompromised individual presenting with rapidly progressive rhinocerebral involvement. An extremely rare variant of central nervous system mucormycosis isolated to the basal ganglia in an i...

    journal_title:World neurosurgery

    pub_type: 杂志文章,评审


    authors: Hazama A,Galgano M,Fullmer J,Hall W,Chin L

    更新日期:2017-02-01 00:00:00

  • Posterior Cerebral Artery Pseudoaneurysm, a Rare Complication of Pituitary Tumor Transsphenoidal Surgery: Case Report and Literature Review.

    abstract::Endoscopic endonasal transsphenoidal surgery for pituitary tumors has been the standard therapy for decades. This approach offers surgeons an effective, safe, and wide exposure to the pituitary gland, with a relatively low mortality rate and acceptable complication rates. However, severe complications, including cereb...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Lee CH,Chen SM,Lui TN

    更新日期:2015-11-01 00:00:00

  • Efficacy of the Endoscopic Triportal Transmaxillary Approach for Treating Lateral Middle Skull Base Tumors: A Technical Note and Retrospective Case Series.

    abstract:BACKGROUND:The endoscopic approach, chiefly via the maxillary sinus, has growing applications for the lateral skull base, and can be classified into the use of "endonasal" or "sublabial" entry. Although the endonasal transmaxillary approach has been well accepted, it has a limitation with respect to the lateral exposur...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Umehara T,Kinoshita M,Hayama M,Shikina T,Fujimoto Y,Yohei M,Inohara H,Kishima H

    更新日期:2020-10-01 00:00:00

  • Pathological Changes in Surgically Resected Cystic Cerebral Cavernous Malformation 13 Years After Radiosurgery: Case Report and Review of the Literature.

    abstract:BACKGROUND:Stereotactic radiosurgery (SRS) as a treatment for cerebral cavernous malformation (CCM) has been controversial, but there are few pathological reports showing its long-term therapeutic effect, and literature reporting the CCM cyst formation after SRS is also rare. CASE DESCRIPTION:We present a 30-year-old ...

    journal_title:World neurosurgery



    authors: Wang C,Yu B,Zhang F,Zheng K,Feng Y

    更新日期:2020-11-01 00:00:00

  • Neuroprotective Effects of Hesperidin on Cerebral Vasospasm After Experimental Subarachnoid Hemorrhage in Rats: Biochemical, Pathologic, and Histomorphometric Analysis.

    abstract:OBJECTIVE:We examined the protective effects of hesperidin on cerebral vasospasm by establishing an experimental rat model of subarachnoid hemorrhage and performing biochemical, pathologic, and histomorphometric analysis on these data. METHODS:Forty albino Wistar rats were randomly divided into 5 groups of n = 8 in ea...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Aydogmus E,Gul S,Bahadir B

    更新日期:2019-02-01 00:00:00

  • Predictive Factors for Rathke's Cleft Cyst Consistency.

    abstract:OBJECTIVE:Rathke's cleft cysts (RCCs) may have various anatomic, clinical, and radiologic characteristics, which may be related to their differences in texture or consistency. The purpose of the study was to investigate RCCs based on consistency. METHODS:We retrospectively reviewed 25 cases of patients with RCCs who u...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Ozoner B,Aydin S,Akgun MY,Durmaz ES,Sahin S,Gazioglu N,Kizilkilic O,Kadioglu P,Tanriover N

    更新日期:2019-08-01 00:00:00

  • Application of Midazolam Injection in Patients with Intraoperative Nerve Block Anesthesia and Sedation Assisted by Medical Image.

    abstract::This paper explores the clinical effect of midazolam as an adjuvant analgesic and tranquilizer after brachial plexus block anaesthesia with the aid of medical imaging. The paper selected 106 patients who underwent elective unilateral upper extremity surgery from January 2017 to December 2019, and randomly divided them...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Xu X,Hu X,Han Y,Zhuang X,Tang R,Xu Y

    更新日期:2020-11-26 00:00:00

  • Analysis of Treatment Tolerance and Factors Associated with Overall Survival in Elderly Patients with Glioblastoma.

    abstract:BACKGROUND:As the population ages, the proportion of elderly patients with glioblastomas has increased. Recently, many researchers have focused on the treatments available to and prognoses in elderly patients with glioblastomas. METHODS:We conducted a retrospective study of glioblastoma patients aged 60 years old or o...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Zhang C,Wang X,Hao S,Su Z,Zhang P,Li Y,Song G,Yu L,Wang J,Ji N,Xie J,Gao Z

    更新日期:2016-11-01 00:00:00

  • Dysembryoplastic Neuroepithelial Tumor with Enlarging Heterogeneously Enhancing Organizing Hematoma.

    abstract::This report portrays an unusual presentation of a dysembryoplastic neuroepithelial tumor characterized by a chronic, enlarging, heterogeneously enhancing organizing hematoma. Differential diagnoses included the malignant transformation of a low-grade glioma, radiation necrosis, and radiation-induced cavernoma. A dysem...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: El Ahmadieh TY,Cai C,Mickey BE

    更新日期:2019-11-01 00:00:00

  • Factors Predicting Ventricle Volume Increase After Aneurysmal Clipping in Patients with Subarachnoid Hemorrhage.

    abstract:OBJECTIVE:Although many studies have evaluated risk factors associated with hydrocephalus after aneurysmal subarachnoid hemorrhage, specific ventricle volume changes after subarachnoid hemorrhage have not been evaluated. We sought to evaluate factors predicting ventricle volume enlargement in patients with aneurysmal s...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Bang JH,Na MK,Kim CH,Kim JM,Cheong JH,Ryu JI,Han MH

    更新日期:2017-12-01 00:00:00

  • Anterior Cervical Discectomy and Fusion Versus Hybrid Decompression and Fusion for the Treatment of 3-Level Cervical Spondylotic Myelopathy: A Comparative Analysis of Cervical Sagittal Balance and Outcomes.

    abstract:OBJECTIVE:To compare the cervical sagittal balance and surgical outcomes between anterior cervical discectomy and fusion (ACDF) and hybrid decompression and fusion (HDF; 1-level corpectomy combined with 1-level discectomy) for consecutive 3-level cervical spondylotic myelopathy (CSM). METHODS:From January 2013 to June...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Xu Z,Rao H,Zhang L,Li G,Xu Z,Xu W

    更新日期:2019-12-01 00:00:00

  • A Case of Rapid Malignant Brain Swelling Subacutely After Reperfusion Therapy for Internal Carotid Artery Occlusion.

    abstract:BACKGROUND:Severe complications after reperfusion therapy for acute major vessel occlusion are not well described. We present an extremely rare case of a patient with rapid malignant brain swelling subacutely after acute ischemic stroke. CASE DESCRIPTION:An 84-year-old man underwent reperfusion therapy for acute left ...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Yamaguchi S,Hamabe J,Horie N,Kishikawa T,Yagi N,Suyama K

    更新日期:2018-10-01 00:00:00

  • Is Gross Total Resection Reasonable in Adults with Craniopharyngiomas with Hypothalamic Involvement?

    abstract:OBJECTIVE:The treatment of hypothalamus-invading craniopharyngiomas, based on pediatric experience, is subtotal resection (STR) with radiotherapy. This strategy sometimes leads to uncontrollable tumor progression. In adults, with the use of endoscopic endonasal surgery (EES), does removing the hypothalamic part of the ...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Apra C,Enachescu C,Lapras V,Raverot G,Jouanneau E

    更新日期:2019-09-01 00:00:00

  • Embolectomy Through Aneurysm Wall for Iatrogenic Occlusion of M1 Portion During Coil Embolization: Technical Note for Transaneurysmal Embolectomy.

    abstract:OBJECTIVE:We describe the technique for surgical "transaneurysmal" embolectomy in a patient with subarachnoid hemorrhage and multiple cerebral aneurysms who manifested large-vessel occlusion during coil embolization. METHODS:An 84-year-old woman with subarachnoid hemorrhage and bilateral internal carotid artery (ICA)-...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Suzuki M,Mizunari T,Iwamoto N,Morita A

    更新日期:2018-06-01 00:00:00

  • Dorsal Cervical Spinal Cord Herniation Precipitated by Kyphosis Deformity Correction for Spinal Cord Tethering.

    abstract:INTRODUCTION:Cervical spinal cord herniation is a rare clinical entity. Reported after previous intradural surgery or surgery complicated by durotomy, patients return several months to years later with symptoms of worsening myelopathy. Herein is presented a case of a 51-year-old female patient with spinal cord herniati...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Heller RS,Hwang SW,Riesenburger RI

    更新日期:2017-04-01 00:00:00

  • Roadmap for Developing Complex Virtual Reality Simulation Scenarios: Subpial Neurosurgical Tumor Resection Model.

    abstract:BACKGROUND:Advancement and evolution of current virtual reality (VR) surgical simulation technologies are integral to improve the available armamentarium of surgical skill education. This is especially important in high-risk surgical specialties. Such fields including neurosurgery are beginning to explore the utilizati...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Sabbagh AJ,Bajunaid KM,Alarifi N,Winkler-Schwartz A,Alsideiri G,Al-Zhrani G,Alotaibi FE,Bugdadi A,Laroche D,Del Maestro RF

    更新日期:2020-07-01 00:00:00

  • The Nuchal Lines as Anatomic Landmarks to Dissect the Muscles in the Far Lateral Approach.

    abstract:BACKGROUND:A critical step in the far lateral approach (FLA) is exposure of the V3 segment of the vertebral artery, located deep in the suboccipital triangle (SOT). Safe exposure of the SOT is achieved by means of a plane-by-plane dissection, which carries the risk of devascularization. A suitable alternative is to lif...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Campero A,Villalonga JF,Elizalde RL,Ajler P

    更新日期:2018-05-01 00:00:00

  • Radial Arterial Access for Thoracic Intraoperative Spinal Angiography in the Prone Position.

    abstract:BACKGROUND:Verification of complete occlusion or resection of neurovascular lesions is often performed using intraoperative angiography. Surgery for spinal vascular lesions such as arteriovenous malformations (AVMs) and arteriovenous fistulas (AVFs) is typically performed with the patient in the prone position, making ...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Haynes J,Nossek E,Shapiro M,Chancellor B,Frempong-Boadu A,Peschillo S,Alves H,Tanweer O,Gordon D,Raz E

    更新日期:2020-05-01 00:00:00

  • A Systematic Review of Prophylactic Antibiotic Use in Endoscopic Endonasal Transsphenoidal Surgery for Pituitary Lesions.

    abstract:BACKGROUND:The benefit of prophylactic antibiotic use in endoscopic endonasal transsphenoidal surgery (EETS) for pituitary lesions is controversial. Many surgeons administer antibiotics perioperatively not based on clear guidelines but to be safe. The purpose of this study was to determine if antibiotic prophylaxis use...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Moldovan ID,Agbi C,Kilty S,Alkherayf F

    更新日期:2019-08-01 00:00:00

  • Cerebral arteriovenous malformations: issues of the interplay between stereotactic radiosurgery and endovascular surgical therapy.

    abstract::Intracranial arteriovenous malformations (AVMs) are congenital lesions frequently diagnosed as a result of hemorrhage or other neurological symptoms. Prevention of such devastating neurological injury has promoted a variety of treatment strategies. The rich history of multimodal therapy in the treatment of AVMs includ...

    journal_title:World neurosurgery

    pub_type: 杂志文章,评审


    authors: Yashar P,Amar AP,Giannotta SL,Yu C,Pagnini PG,Liu CY,Apuzzo ML

    更新日期:2011-05-01 00:00:00

  • Intraspinal Pressure Monitoring and Extensive Duroplasty in the Acute Phase of Traumatic Spinal Cord Injury: A Systematic Review.

    abstract:OBJECTIVE:The prognosis in cervical spinal cord injury is poor, and surgical and neurointensive care management need further improvement. Monitoring of the intraspinal pressure (ISP) at an early stage after traumatic spinal cord injury (tSCI) is useful clinically. MATERIALS AND METHODS:Obtaining continuous spinal cord...

    journal_title:World neurosurgery

    pub_type: 杂志文章,评审


    authors: Tykocki T,Poniatowski Ł,Czyż M,Koziara M,Wynne-Jones G

    更新日期:2017-09-01 00:00:00

  • Results of a Single Center's Stenting Procedure for the Treatment of Carotid Stenosis.

    abstract:BACKGROUND:Stenting may be a safer alternative to endarterectomy for treating carotid artery stenosis (CAS), but its long-term efficacy is uncertain. There is a lack of long-term and noncontrolled clinical trial data that reflects "real-world" CAS. This study aimed to analyze the long-term efficacy and safety of our ce...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Vieira-Leite C,Mosqueira AJ,Arias-Rivas S,Rodríguez-Yáñez M,Pumar JM

    更新日期:2020-01-01 00:00:00

  • Neurogenic Cough Associated with Hyperintensity in Dorsal Medulla: Case Report and Anatomical Discussion.

    abstract:BACKGROUND:The nucleus tractus solitarius and paratrigeminal nucleus, which are implicated in the processing of airway-derived sensory information, are found in the dorsal medulla. The mechanism and localization of higher-order processing of urge to cough is poorly understood, and much of the existing anatomical locali...

    journal_title:World neurosurgery



    authors: Paranathala MP,Mitchell P

    更新日期:2020-12-01 00:00:00

  • A 3-Dimensional Finite Element Analysis of Adjacent Segment Disk Degeneration Induced by Transforaminal Lumbar Interbody Fusion After Pedicle Screw Fixation.

    abstract:BACKGROUND:Transforaminal lumbar interbody fusion (TLIF) is an effective treatment of upper lumbar intervertebral disk herniation. However, its clinical efficacy for adjacent segment disk degeneration (ASDD) remains undefined. Therefore, the biomechanical evaluation of ASDD caused by TLIF after pedicle screw fixation (...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Guo TM,Lu J,Xing YL,Liu GX,Zhu HY,Yang L,Qiao XM

    更新日期:2018-11-29 00:00:00

  • Visual Outcomes After Endoscopic Endonasal Resection of Orbital Lesions.

    abstract:BACKGROUND:The endoscopic endonasal approach (EEA) has been increasing in popularity as an alternative to traditional transcranial and transorbital approaches in the treatment of orbital pathological entities. The purpose of the present study was to examine the outcomes of patients who had undergone EEA resection of or...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Yang K,Ellenbogen Y,Algird AR,Sommer DD,Reddy K

    更新日期:2020-07-01 00:00:00

  • Single Posterior Approach versus Combined Anterior and Posterior Approach in the Treatment of Spinal Tuberculosis: A Meta-Analysis.

    abstract:BACKGROUND:Spinal tuberculosis is the most common form of tuberculosis affecting bone and often needs surgical treatment. Single anterior, single posterior, and combined anterior and posterior approaches are the 3 most commonly used approaches in surgical treatment. Clinically, the choice of optimal surgical approach r...

    journal_title:World neurosurgery

    pub_type: 杂志文章,评审


    authors: Zhong Y,Yang K,Ye Y,Huang W,Liu W,Luo J

    更新日期:2020-12-11 00:00:00

  • Cerebral vasospasm and health-related quality of life after subarachnoid hemorrhage.

    abstract:OBJECTIVE:To examine the influence of cerebral vasospasm on health-related quality of life after subarachnoid hemorrhage. An additional objective was to determine how the timing of nimodipine therapy can influence health-related quality of life. METHODS:Patients treated between 1998 and 2008 for nontraumatic subarachn...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Tjahjadi M,König R,Wirtz CR,Woischneck D,Kapapa T

    更新日期:2013-07-01 00:00:00