RASEF expression correlates with hormone receptor status in breast cancer.

abstract：:Increasing evidence has suggested that microRNAs (miRNAs; miRs) are extensively involved in the progression of chondrosarcoma (CHS). However, few studies have investigated the functional role of miR-525 in CHS tissues and cells. In the present study, it was discovered that miR-525 levels were decreased in CHS tissues ...

journal_title：Oncology letters

authors： Liu B,Song X,Yan Z,Yang H,Shi Y,Wu J

更新日期：2019-01-01 00:00:00

abstract：:Early mitotic inhibitor-1 (Emi1), as a key cell cycle regulatory gene, induces S phase and mitotic entry by controlling anaphase-promoting complex substrates. Emi1 overexpression may be a prognostic factor for patients with invasive breast cancer. However, its expression and clinical significance in esophageal squamou...

journal_title：Oncology letters

authors： Guan C,Zhang J,Zhang J,Shi H,Ni R

更新日期：2016-07-01 00:00:00

abstract：:Vasculogenic mimicry (VM), a new pattern of tumor microcirculation, is important for the growth and progression of tumors. Epithelial-mesenchymal transition (EMT) is pivotal in malignant tumor progression and VM formation. With increasing knowledge of cancer stem cell (CSC) phenotypes and functions, increasing evidenc...

journal_title：Oncology letters

authors： Fan YL,Zheng M,Tang YL,Liang XH

更新日期：2013-11-01 00:00:00

abstract：:Nasopharyngeal carcinoma (NPC) is a common type of cancer worldwide. Long non-coding RNAs (lncRNAs) have been demonstrated to be associated with the development of multiple types of human cancer. The present study aimed to identify the potential role of lncRNA colon cancer associated transcript 1 (CCAT1) in NPC. Rever...

journal_title：Oncology letters

authors： Dong Y,Yuan H,Jin G

更新日期：2018-08-01 00:00:00

abstract：:Dermatofibrosarcoma protuberans (DFSP) is a relatively rare low-grade sarcoma that occasionally exhibits melanin-containing spindle cells within the tumor. Fibrosarcomatous DFSP (FS-DFSP) is a variant that is characterized by areas which are histopathologically indistinguishable from fibrosarcoma. In the present study...

journal_title：Oncology letters

authors： Ishida M,Okabe H

更新日期：2012-09-01 00:00:00

abstract：:The present study compared two methods for the detection of severe cervical dysplasia in women with atypical squamous cells of underdetermined significance (ASC-US) cytology; digital colposcopy with adjunctive dynamic spectral imaging (DSI) and conventional colposcopy. IMPROVE-COLPO was a two-arm cross-sectional study...

journal_title：Oncology letters

authors： Harris KE,Lavin PT,Akin MD,Papagiannakis E,Denardis S

更新日期：2020-10-01 00:00:00

abstract：:Glioma is one of the most prevalent types of malignancy in the central nervous system worldwide, and the prognosis of patients with late stage glioma remains poor. Thus, the development of promising therapeutic strategies against glioma is essential. Long non-coding RNAs (lncRNAs) are functional RNA molecules involved...

journal_title：Oncology letters

authors： Guan N,Wang R,Feng X,Li C,Guo W

更新日期：2020-09-01 00:00:00

abstract：:Little information from clinical trials is available regarding the efficacy of trastuzumab treatment in subcentimetric breast carcinomas (BCs). The aim of this study was to verify the existence of correlations between HER2 and hormone receptor status, Ki67 values, grade, histotype and node involvement in a cohort of p...

journal_title：Oncology letters

authors： Ieni A,Giuffrè G,Lanzafame S,Nuciforo G,Curduman M,Villari L,Roz E,Certo G,Cabibi D,Salomone E,Labate A,Messina D,Franco V,Adamo V,Tuccari G

更新日期：2012-01-01 00:00:00

abstract：:The liver kinase B1 (LKB1)/5'-adenosine monophosphate-activated protein kinase pathway has been reported to facilitate glioma cell growth by improving growth conditions. To investigate the clinical significance of LKB1 in human gliomas western blot analysis and quantitative polymerase chain reaction experiments were p...

journal_title：Oncology letters

authors： Huang J,Chen H,Wei Q,Zhang Z,Zhong Z,Xu Y

更新日期：2017-03-01 00:00:00

abstract：:Numerous studies have indicated that microRNAs (miRs), a group of small non-coding RNAs, are determining regulatory elements involved in the pathogenesis of various types of cancer, including cervical cancer (CC). Although miR-21-5p upregulation has been demonstrated to associate with tumorigenesis by controlling the ...

journal_title：Oncology letters

authors： Cai L,Wang W,Li X,Dong T,Zhang Q,Zhu B,Zhao H,Wu S

更新日期：2018-04-01 00:00:00

abstract：:Bone metastasis is an uncommon event in advanced gastric cancer patients and bone metastases are rarely detected as isolated lesions. However, eleven years after treatment for locally advanced gastric cancer, including total gastrectomy followed by adjuvant chemotherapy, a 49-year-old female was admitted to the IX Div...

journal_title：Oncology letters

authors： Iovino F,Orditura M,Auriemma PP,Ciorra FR,Giordano G,Orabona C,Bara F,Sergio R,Savastano B,Fabozzi A,Laterza MM,Ventriglia J,Petrillo A,Della Corte CM,DE Vita F

更新日期：2015-03-01 00:00:00

abstract：:Pleomorphic adenomas (PAs) of salivary glands are the most frequent entity of solid parotid tumors. Nonetheless, their genetics is not yet well understood. Thus, the current study characterized 14 PAs using a unique combination of cytogenetic, molecular cytogenetic and/or molecular karyotyping based approaches. The cu...

journal_title：Oncology letters

authors： Thielker J,Weise A,Othman MAK,Carreria IM,Melo JB,Von Eggeling F,Guntinas-Lichius O,Ziegler M,Liehr T

更新日期：2020-02-01 00:00:00

abstract：:The causes of lung cancer in never-smokers remain unclear. The potential contribution of human papillomavirus (HPV) to the carcinogenesis of non-small cell lung cancer (NSCLC) has been reported. In 2008, a prospective registry of never-smokers with NSCLC was established at the Kinki-Chuo Chest Medical Center, Sakai, O...

journal_title：Oncology letters

authors： Isa SI,Kurahara Y,Yamamoto S,Tamiya A,Omachi N,Asami K,Okishio K,Utsumi T,Ito N,Yoon HE,Matsumura A,Atagi S,Kawaguchi T

更新日期：2015-02-01 00:00:00

abstract：:Malignant pleural mesothelioma (MPM) is associated with a history of heavy, long-term exposure to asbestos. However, MPM may also be associated with simian virus 40 (SV40), a polyomavirus. The association between SV40 and MPM remains unclear. The present study was conducted in order to investigate the proportion of SV...

journal_title：Oncology letters

authors： Thanh TD,Tho NV,Lam NS,Dung NH,Tabata C,Nakano Y

更新日期：2016-03-01 00:00:00

abstract：:The aim of the present study was to evaluate the clinical importance of melanoma-associated antigen D4 (MAGE-D4) expression in glioma, and to identify it as a valuable prognostic biomarker and therapeutic target. To achieve this, the expression of MAGE-D4 protein in 124 tumor tissues from patients with glioma was meas...

journal_title：Oncology letters

authors： Yan J,Wen J,Wei ZD,Li XS,Li P,Xiao SW

更新日期：2018-04-01 00:00:00

abstract：:In the present study, the expression level of microRNA-146a-5p (miR-146a-5p) in breast cancer tissue and cell lines was investigated and its effects on proliferation of breast cancer cells. miR-146a-5p expression was detected by reverse transcription-quantitative polymerase chain reaction in breast cancer tissues, par...

journal_title：Oncology letters

authors： Gao W,Hua J,Jia Z,Ding J,Han Z,Dong Y,Lin Q,Yao Y

更新日期：2018-06-01 00:00:00

abstract：:Colorectal cancer (CRC) is one of the major causes of cancer-associated mortality worldwide. Wnt family member 10A (Wnt10a) is an oncogene associated with the carcinogenesis and progression of renal cell carcinoma, and is strongly expressed in the CRC cell line SW480. However, the role of Wnt10a in CRC has been rarely...

journal_title：Oncology letters

authors： Li J,Zhang Z,Wang L,Zhang Y

更新日期：2019-04-01 00:00:00

abstract：:The transforming growth factor-β (TGFβ) pathway plays an important role in various types of human cancer. However, the role of TGFB1 -509C/T and TGFBR2 -875A/G polymorphisms in gastric cancer is controversial. We aimed to investigate the associations between these polymorphisms and gastric cancer susceptibility, clini...

journal_title：Oncology letters

authors： Xu L,Zeng Z,Chen B,Wu X,Yu J,Xue L,Tian L,Wang Y,Chen M,Sung JJ,Hu P

更新日期：2011-03-01 00:00:00

abstract：:Although Wilms tumor 1 (WT1)-associated protein (WTAP) was initially found to be a specific WT1-binding protein, it has increasingly attracted attention because of its oncogenic role in various types of malignancies, including cholangiocarcinoma, glioblastoma and acute myeloid leukemia. However, the clinical impact of...

journal_title：Oncology letters

authors： Li BQ,Huang S,Shao QQ,Sun J,Zhou L,You L,Zhang TP,Liao Q,Guo JC,Zhao YP

更新日期：2017-04-01 00:00:00

abstract：:Human papillomavirus (HPV) is widely known as a cause of cervical intraepithelial neoplasia (CIN) and cervical cancer. The mechanisms involved have been studied by numerous studies. The integration of the virus genome into the host cells results in the abnormal regulation of cell cycle control. HPV can also induce imm...

journal_title：Oncology letters

authors： Song D,Li H,Li H,Dai J

更新日期：2015-08-01 00:00:00

abstract：:Sigma-1 receptor (sigma-1R), a 25-kDa integral membrane protein, is expressed at a high density in various tumor cell lines and its ligands mediate tumor cell proliferation. However, the effect of this receptor on proliferation and the associated intracellular molecules in tumors remains unclear. The present study aim...

journal_title：Oncology letters

authors： Wu Y,Bai X,Li X,Zhu C,Wu ZP

更新日期：2018-11-01 00:00:00

abstract：:Pancreatic ductal adenocarcinoma (PDA) is an aggressive malignant disease that is resistant to various chemotherapeutic agents and commonly relapses. Efficient elimination of metastasized PDA is critical for a positive post-surgical treatment outcome. The present study analyzed the effect of the B-cell lymphoma-2 (Bcl...

journal_title：Oncology letters

authors： Kasai S,Sasaki T,Watanabe A,Nishiya M,Yasuhira S,Shibazaki M,Maesawa C

更新日期：2017-07-01 00:00:00

abstract：:This study aimed to determine the relationship between human papillomavirus (HPV) and nuclear factor-κB (NF-κB) in cervical cancer using 62 tissues of cervical cancer, and to compare the findings to penile cancer. HPV-DNA integration is a crucial factor for malignant transformation in cervical cancer and can be identi...

journal_title：Oncology letters

authors： Senba M,Buziba N,Mori N,Fujita S,Morimoto K,Wada A,Toriyama K

更新日期：2011-01-01 00:00:00

abstract：:We experienced a rare case of primary intracranial choriocarcinoma treated successfully with synchronous chemotherapy and radiotherapy followed by three consecutive courses of chemotherapy without surgery. A 19-year-old male patient presented with a two-week history of diplopia, headache, nausea and vomiting. Neurolog...

journal_title：Oncology letters

authors： Kim M,Yun J,Hur SM,Moon JJ,Nam JH,Kim SH,Kim HJ,Kim CK,Park SK,Hong DS

更新日期：2012-12-01 00:00:00

abstract：:Liver cancer, which is the second leading cause of tumor-associated mortality, is of great concern worldwide due to its resistance to chemotherapeutic drugs. Transcatheter arterial chemoembolization (TACE) has previously been used as a treatment for unresectable liver tumors in China; however, the response to TACE tre...

journal_title：Oncology letters

authors： Liu DX,Li PP,Guo JP,Li LL,Guo B,Jiao HB,Wu JH,Chen JM

更新日期：2019-01-01 00:00:00

abstract：:Breast cancer 1 (BRCA1) and insulin-like growth factor 1 receptor (IGF1R) are critical in ovarian cancer progression. However, the crosstalk between the BRCA1 and IGF1R signaling pathways in ovarian cancer remains largely unknown. The effects of BRCA1 on IGF1R were assessed in 121 serous ovarian cancer patients (BRCA1...

journal_title：Oncology letters

authors： Liu B,Li D,Guan YF

更新日期：2014-05-01 00:00:00

abstract：:The anticancer effect of Scutellaria baicalensis extract has recently become a topic of interest. In this study, the anticancer effects and underlying mechanisms of wogonoside, the main constituent of Scutellaria baicalensis, were investigated in a human hepatocellular carcinoma (HCC) cell line in vitro. The effects o...

journal_title：Oncology letters

authors： Li Y,Tu M,Cheng C,Tian J,Zhang F,Deng Z,Li X,Li Z,Liu Y,Lei G

更新日期：2015-09-01 00:00:00

abstract：:Percutaneous transluminal angioplasty using balloon catheters for Budd-Chiari syndrome (BCS) and transcatheter arterial chemoembolization (TACE) for unresectable hepatocellular carcinoma (HCC) have become increasingly accepted as alternative therapeutic modalities. However, few studies have investigated the clinical e...

journal_title：Oncology letters

authors： Zhang QQ,Zu MH,Xu H,Gu YM,Wang WL,Gao ZK

更新日期：2013-08-01 00:00:00

abstract：:Indocyanine green (ICG) fluorescence imaging represents a promising method for sentinel node (SN) biopsy in laparoscopic gastric surgery due to its signal stability. In the present study, the suitability and optimal settings of ICG fluorescence imaging for SN biopsy in early gastric cancer were determined. Patients wi...

journal_title：Oncology letters

authors： Kinami S,Oonishi T,Fujita J,Tomita Y,Funaki H,Fujita H,Nakano Y,Ueda N,Kosaka T

更新日期：2016-06-01 00:00:00

abstract：:Cholangiocarcinoma (CCA) is a primary malignancy, which is often diagnosed as locally advanced or metastatic. Previous studies have revealed genomic characteristics of CCA in Western patients, however comprehensive genomic features of CCA in Chinese patients have not been well understood. To explore the specific genom...

journal_title：Oncology letters

authors： Tian W,Hu W,Shi X,Liu P,Ma X,Zhao W,Qu L,Zhang S,Shi W,Liu A,Cao J

更新日期：2020-04-01 00:00:00