Abstract:
:Autofluorescence and transmission values of the lens for blue-green light were determined at two locations with the use of identical fluorophotometers: in Coimbra, Portugal, in 44 healthy controls, 15 haemodialysis and 11 renal failure patients, and in Leiden, The Netherlands, in 57 healthy controls, 23 haemodialysis and 47 renal transplant patients. The increase in lens autofluorescence as a function of age was 42% higher in the Portuguese controls than that in the Dutch controls (p less than 0.001), but the lens transmission did not differ significantly (p = 0.21). Significant differences were found between the autofluorescence values of the Portuguese haemodialysis and renal failure patients and those of age-matched local controls (+18%, p = 0.009, and +26%, p = 0.03, respectively), as well as between the lens transmission values of the Portuguese renal failure patients and those of age-matched local controls (-2%, p = 0.03). In the renal transplant patients the average autofluorescence and lens transmission values were equal to those of the local controls (within 3%) and independent of the number of anti-rejection treatments administered.
journal_name
Ophthalmic Resjournal_title
Ophthalmic researchauthors
van Wirdum E,Mota MC,van Best JA,Leite E,Kappelhof JP,Faria de Abreu JR,Paul LC,Freitas Martins J,Oosterhuis JA,Marques Adoi
10.1159/000266736subject
Has Abstractpub_date
1988-01-01 00:00:00pages
317-26issue
5eissn
0030-3747issn
1423-0259journal_volume
20pub_type
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更新日期:2012-01-01 00:00:00
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journal_title:Ophthalmic research
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更新日期:1982-01-01 00:00:00
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更新日期:2020-04-20 00:00:00
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更新日期:1994-01-01 00:00:00
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更新日期:2014-01-01 00:00:00
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journal_title:Ophthalmic research
pub_type: 杂志文章
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更新日期:1986-01-01 00:00:00
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journal_title:Ophthalmic research
pub_type: 杂志文章
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更新日期:1986-01-01 00:00:00
abstract:PURPOSE:Primary open-angle glaucoma (POAG) is a chronic progressive optic neuropathy, leading to degeneration of retinal ganglion cells and characteristic morphological changes at the optic disc. In advanced stages of the disease, functional tests, such as standard automated perimetry (SAP), are the main diagnostic too...
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更新日期:2020-01-01 00:00:00
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journal_title:Ophthalmic research
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更新日期:2018-01-01 00:00:00