Abstract：
:Monoclonal antibodies against calcitonin gene-related peptide (CGRP) or its receptor (CLR + RAMP1) offer considerable improvements over existing drugs in migraine prophylaxis and are the first designed to act on the trigeminal pain system. Erenumab is approved by the FDA and EMA and has reached the market since May 2018. Two antibodies, fremanezumab and galcanezumab, directed towards the CGRP ligand, were approved by the FDA in September 2018. To view this Bench to Bedside, open or download the PDF.
journal_name
Celljournal_title
Cellauthors
Edvinsson Ldoi
10.1016/j.cell.2018.11.049subject
Has Abstractpub_date
2018-12-13 00:00:00pages
1719issue
7eissn
0092-8674issn
1097-4172pii
S0092-8674(18)31574-5journal_volume
175pub_type
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