Left ventricular hypertrophy is a possible biomarker for early mortality after type B aortic dissection.


OBJECTIVE:Data regarding the cardiac abnormalities associated with Stanford type B aortic dissection (TBAD) and whether these abnormalities are related to outcomes are limited. We describe the prevalence of cardiac abnormalities in patients with TBAD as detected by echocardiography. METHODS:This retrospective review included patients with TBAD presenting between 1990 and 2016. Echocardiograms performed within 6 weeks of acute TBAD were reviewed. Cardiac function, valve abnormalities, and stigmata of hypertensive heart disease including left ventricular hypertrophy (LVH) were ascertained. Characteristics of patients who did and did not receive echocardiograms were compared. Outcomes of patients with and without evidence of LVH on echocardiography were also compared. RESULTS:Of 239 patients with TBAD, 90 had echocardiograms performed within 6 weeks of acute TBAD (74% male; mean age, 57.8 ± 13.2 years). Echocardiograms were obtained at a median of 2 days (range, 0-41 days) from acute TBAD. Patients who had echocardiograms were more likely to present with malperfusion (28% vs 14%; P < .01) and had a trend toward increased operative repair during the subacute phase (17.4% vs 9.5%; P = .07) compared with patients who did not receive an echocardiogram. A majority of patients (57%) had at least mild LVH, including 39% of patients without a prior diagnosis of hypertension. Fibrocalcific changes associated with hypertension, including aortic sclerosis and mitral annular calcification, were noted in 40% and 11% of the patients, respectively. Among patients with LVH, there was a trend toward higher all-cause mortality (35% vs 23%; P = .21) and a younger age at death (58 ± 14 years vs 66 ± 13 years; P = .19) despite a similar age at TBAD onset. In a multivariable analysis controlling for age, sex, and admission estimated glomerular filtration rate, LVH independently predicted all-cause mortality (hazard ratio, 2.38; 95% confidence interval, 1.02-5.56; P = .04). CONCLUSIONS:LVH and other findings of hypertensive heart disease are common in patients with TBAD. LVH predicted all-cause mortality after TBAD in this small group of patients. Further exploration of the relationship between the chronic effects of hypertension and using LVH as an objective biomarker to risk stratify patients with TBAD and long-term outcomes after TBAD is warranted.


J Vasc Surg


Taylor AP,Freeman RV,Bartek MA,Shalhub S




Has Abstract


2019-06-01 00:00:00














  • Transthoracic repair of innominate and common carotid artery disease: immediate and long-term outcome for 100 consecutive surgical reconstructions.

    abstract:PURPOSE:This is a review of 100 consecutive supraaortic trunk reconstructions (SAT) performed over 16 years. METHODS:There were eight innominate endarterectomies and 92 bypass procedures based on the thoracic aorta (n = 86) or proximal innominate artery (n = 6) in 98 patients 24 to 79 years of age. Indications include...

    journal_title:Journal of vascular surgery

    pub_type: 杂志文章


    authors: Berguer R,Morasch MD,Kline RA

    更新日期:1998-01-01 00:00:00

  • Renal artery aneurysm: selective treatment for hypertension and prevention of rupture.

    abstract::Thirty-nine patients with renal artery aneurysm (RAA) were seen over a period of 15 years. Among 20 women and 19 men, 31 were found to have solitary aneurysms, and eight had multiple RAA. Thirty-three patients had diastolic hypertension; nine of them proved to be of renovascular origin. Of the 18 patients who underwen...

    journal_title:Journal of vascular surgery

    pub_type: 杂志文章


    authors: Martin RS 3rd,Meacham PW,Ditesheim JA,Mulherin JL Jr,Edwards WH

    更新日期:1989-01-01 00:00:00

  • Description of a risk predictive model of 30-day postoperative mortality after elective abdominal aortic aneurysm repair.

    abstract:OBJECTIVE:Despite vast improvement in the field of vascular surgery, elective abdominal aortic aneurysm (AAA) repair still leads to perioperative death. Patients with asymptomatic AAAs, therefore, would benefit from an individual risk assessment to help with decisions regarding operative intervention. The purpose of th...

    journal_title:Journal of vascular surgery

    pub_type: 杂志文章


    authors: Eslami MH,Rybin DV,Doros G,Farber A

    更新日期:2017-01-01 00:00:00

  • In situ repair of mycotic abdominal aortic aneurysms with rifampin-bonded gelatin-impregnated Dacron grafts: a preliminary case report.

    abstract::Treatment of mycotic aortic aneurysm by excision and extraanatomic bypass is difficult to apply when the infectious process involves the visceral arteries. On the basis of experimental studies in our laboratory that demonstrated prolonged antistaphylococcal activity of rifampin-bonded, gelatin-impregnated Dacron graft...

    journal_title:Journal of vascular surgery

    pub_type: 杂志文章


    authors: Gupta AK,Bandyk DF,Johnson BL

    更新日期:1996-09-01 00:00:00

  • A systematic review and meta-regression analysis of nonoperative management of blunt traumatic thoracic aortic injury in 2897 patients.

    abstract:BACKGROUND:Thoracic endovascular aortic repair has transformed the management of blunt traumatic thoracic aortic injuries (BTTAI). Recent studies have suggested that the nonoperative management (NOM) of BTTAI may be a viable alternative. We investigated the NOM of BTTAI by conducting a systematic review and meta-analys...

    journal_title:Journal of vascular surgery

    pub_type: 杂志文章,meta分析


    authors: Soong TK,Wee IJY,Tseng FS,Syn N,Choong AMTL

    更新日期:2019-09-01 00:00:00

  • In situ fenestration in the aortic arch.

    abstract::In situ fenestration of aortic stent grafts has the potential to allow for continued perfusion of supra-aortic trunks, without the need for extra-anatomic bypass, and without the need for custom-made devices. Angulation of the target vessel relative to the arch is an obstacle to success with this technique. In this re...

    journal_title:Journal of vascular surgery

    pub_type: 杂志文章


    authors: Manning BJ,Ivancev K,Harris PL

    更新日期:2010-08-01 00:00:00

  • Endovascular management of acute aortic dissections.

    abstract:INTRODUCTION:Acute aortic dissection (AAD) is one of the most common aortic emergencies that vascular specialists are asked to manage. Traditional surgical interventions for cases complicated by malperfusion have resulted in significant morbidity and mortality. With increasing availability of thoracic endografts, endov...

    journal_title:Journal of vascular surgery

    pub_type: 杂志文章


    authors: O'Donnell S,Geotchues A,Beavers F,Akbari C,Lowery R,Elmassry S,Ricotta J

    更新日期:2011-11-01 00:00:00

  • Total laparoscopic abdominal aortic aneurysm repair with reimplantation of the inferior mesenteric artery.

    abstract::We performed a total laparoscopic reimplantation of the inferior mesenteric artery (IMA) during laparoscopic infrarenal aortic aneurysm repair. The postoperative course was uneventful, and angiograms showed a patent IMA after reimplantation. To our knowledge, total laparoscopic reimplantation of the IMA in human being...

    journal_title:Journal of vascular surgery

    pub_type: 杂志文章


    authors: Javerliat I,Coggia M,Di Centa I,Kitzis M,Mercier O,Goëau-Brissonnière O

    更新日期:2004-05-01 00:00:00

  • Comparison of covered stents versus bare metal stents for treatment of chronic atherosclerotic mesenteric arterial disease.

    abstract:OBJECTIVE:To compare outcomes of mesenteric angioplasty and stenting using iCAST covered stents (CS; Atrium, Hudson, NH) or bare metal stents (BMS) in patients with chronic mesenteric ischemia (CMI). METHODS:We reviewed the clinical data of 225 patients (65 male and 160 female; mean age, 72 ± 12 years) treated for CMI...

    journal_title:Journal of vascular surgery

    pub_type: 杂志文章,多中心研究


    authors: Oderich GS,Erdoes LS,Lesar C,Mendes BC,Gloviczki P,Cha S,Duncan AA,Bower TC

    更新日期:2013-11-01 00:00:00

  • Lower limb deep venous flow in patients with peripheral vascular disease.

    abstract:PURPOSE:A prospective controlled study was undertaken to determine how peripheral vascular disease (PVD) influences flow in the deep veins of the leg. METHODS:Eighty-nine patients with peripheral vascular disease and 35 age-matched control subjects were studied. The popliteal vein diameter and flow velocity were measu...

    journal_title:Journal of vascular surgery

    pub_type: 杂志文章


    authors: Libertiny G,Hands L

    更新日期:1999-06-01 00:00:00

  • The influence of gender on functional outcomes of lower extremity bypass.

    abstract:OBJECTIVE:Our aim was to evaluate the effect of gender on early and late procedural and functional outcomes of lower extremity bypass (LEB). METHODS:We reviewed the records of 2576 patients (828 women; 32%) who underwent LEB for claudication or critical limb ischemia (CLI) in the Vascular Study Group of New England fr...

    journal_title:Journal of vascular surgery

    pub_type: 杂志文章,多中心研究


    authors: Duffy RP,Adams JE,Callas PW,Schanzer A,Goodney PP,Ricci MA,Cronenwett JL,Bertges DJ,Vascular Study Group of New England.

    更新日期:2014-11-01 00:00:00

  • Optimal fluid management after aortic reconstruction: a prospective study of two crystalloid solutions.

    abstract::To determine optimal fluid management after elective aortic surgery we compared postoperative administration of 5% dextrose Ringer's lactate solution (102 patients) with 5% dextrose half-normal saline solution (80 patients). For 72 hours after operation, intravenous fluids were titrated to maintain urine output betwee...

    journal_title:Journal of vascular surgery

    pub_type: 杂志文章


    authors: Bomberger RA,McGregor B,DePalma RG

    更新日期:1986-08-01 00:00:00

  • Female sex is associated with comparable 5-year outcomes after contemporary endovascular aneurysm repair despite more challenging anatomy.

    abstract:BACKGROUND:Women with abdominal aortic aneurysms less often meet anatomic criteria for endovascular repair and experience worse perioperative and long-term survival. METHODS:We compared long-term survival, aneurysm-related mortality, and rates of endoleaks and reinterventions between male and female patients in the En...

    journal_title:Journal of vascular surgery

    pub_type: 杂志文章


    authors: O'Donnell TFX,Verhagen HJ,Pratesi G,Pratesi C,Teijink JAW,Vermassen FEG,Mwipatayi P,Forbes TL,Schermerhorn ML

    更新日期:2020-04-01 00:00:00

  • Heparin-bonded ePTFE grafts compared with vein grafts in femoropopliteal and femorocrural bypasses: 1- and 2-year results.

    abstract:OBJECTIVE:Many patients with peripheral arterial occlusive disease who require a lower-limb bypass have no available autologous saphenous vein (ASV) for the procedure and thus require a prosthetic graft. Expanded polytetrafluoroethylene (ePTFE) grafts are commonly used, but results with these prostheses have varied, es...

    journal_title:Journal of vascular surgery

    pub_type: 杂志文章


    authors: Daenens K,Schepers S,Fourneau I,Houthoofd S,Nevelsteen A

    更新日期:2009-05-01 00:00:00

  • Peripheral vascular bypass in juvenile-onset diabetes mellitus: are aggressive revascularization attempts justified?

    abstract::This study was performed to evaluate the results of peripheral vascular reconstruction for arterial occlusive disease in patients with juvenile-onset diabetes mellitus. The results of 67 bypass procedures performed on 60 patients with juvenile-onset diabetes mellitus between Jan. 1, 1984 and Dec. 31, 1989, were review...

    journal_title:Journal of vascular surgery

    pub_type: 杂志文章


    authors: Kwolek CJ,Pomposelli FB,Tannenbaum GA,Brophy CM,Gibbons GW,Campbell DR,Freeman DV,Miller A,LoGerfo FW

    更新日期:1992-02-01 00:00:00

  • High hemoglobin A1c associated with increased adverse limb events in peripheral arterial disease patients undergoing revascularization.

    abstract:OBJECTIVE:Diabetes and peripheral arterial disease (PAD) are independently associated with increased risk of amputation. However, the effect of poor glycemic control on adverse limb events has not been studied. We examined the effects of poor glycemic control (high hemoglobin A1c level) on the risk of amputation and mo...

    journal_title:Journal of vascular surgery

    pub_type: 杂志文章


    authors: Arya S,Binney ZO,Khakharia A,Long CA,Brewster LP,Wilson PW,Jordan WD Jr,Duwayri Y

    更新日期:2018-01-01 00:00:00

  • Lower extremity arterial injury: results of 550 cases and review of risk factors associated with limb loss.

    abstract:PURPOSE:We sought to analyze the results of lower limb arterial injury (LLAI) management in a busy metropolitan vascular unit and to identify risk factors associated with limb loss. PATIENTS AND METHODS:Between 1987 and 1997, prospectively collected data on 550 patients with 641 lower limb arterial injuries were analy...

    journal_title:Journal of vascular surgery

    pub_type: 杂志文章,评审


    authors: Hafez HM,Woolgar J,Robbs JV

    更新日期:2001-06-01 00:00:00

  • Duplex-guided balloon angioplasty and stenting for femoropopliteal arterial occlusive disease: an alternative in patients with renal insufficiency.

    abstract:BACKGROUND:The technique of balloon angioplasty of infrainguinal arteries requires standard arteriography and fluoroscopic guidance. We attempted to perform this procedure under duplex guidance to avoid the use of nephrotoxic contrast material and radiation exposure in patients with renal insufficiency. METHODS:Over 1...

    journal_title:Journal of vascular surgery

    pub_type: 杂志文章


    authors: Ascher E,Marks NA,Schutzer RW,Hingorani AP

    更新日期:2005-12-01 00:00:00

  • Update on workforce diversity in vascular surgery.

    abstract:OBJECTIVES:Creating a diverse workforce is paramount to the success of the surgical field. A diverse workforce allows us to meet the health needs of an increasingly diverse population and to bring new ideas to spur technical innovation. The purpose of this study was to assess trends in workforce diversity within vascul...

    journal_title:Journal of vascular surgery

    pub_type: 杂志文章


    authors: Dorsey C,Ross E,Appah-Sampong A,Vela M,Saunders M

    更新日期:2020-12-18 00:00:00

  • Therapeutic site selection is important for the successful development of collateral vessels.

    abstract:BACKGROUND:Induction of collateral development to improve tissue perfusion is a promising approach for the treatment of arterial occlusive diseases. Several growth factors and cells have been reported to increase collateral circulation; however, the appropriate site for the delivery of these factors and cells is unclea...

    journal_title:Journal of vascular surgery

    pub_type: 杂志文章


    authors: Nishiyama A,Koyama H,Miyata T,Watanabe T

    更新日期:2015-07-01 00:00:00

  • Current indications for axillounifemoral and axillobifemoral bypass grafts.

    abstract::Revascularization of the lower extremities may require an axillofemoral bypass when an aortobifemoral bypass is contraindicated. Thirty-one patients underwent axillounifemoral and 59 had an axillobifemoral bypass, with a mortality rate of 9%. The indication for operation was limb salvage in 67%, intra-abdominal sepsis...

    journal_title:Journal of vascular surgery

    pub_type: 杂志文章


    authors: Kalman PG,Hosang M,Cina C,Johnston KW,Ameli FM,Walker PM,Provan JL

    更新日期:1987-06-01 00:00:00

  • Final operative and midterm results of the European experience in the RELAY Endovascular Registry for Thoracic Disease (RESTORE) study.

    abstract:PURPOSE:Thoracic endovascular aortic repair is increasingly becoming the standard treatment of many thoracic aortic pathologies. New reliable and accurate stent grafts are emerging to widen the endovascular treatment options. We report the results of RELAY (Bolton Medical, Barcelona, Spain) in the large RELAY Endovascu...

    journal_title:Journal of vascular surgery

    pub_type: 杂志文章,多中心研究


    authors: Riambau V,Zipfel B,Coppi G,Czerny M,Tealdi DG,Ferro C,Chiesa R,Sassi C,Rousseau H,Berti S,RELAY Endovascular Registry for Thoracic Disease RESTORE Investigators.

    更新日期:2011-03-01 00:00:00

  • Intracranial hemorrhage after carotid endarterectomy.

    abstract::Among 1500 carotid endarterectomies performed between 1975 and 1984, 11 ipsilateral intracranial hemorrhages (IH) occurred between the first and tenth postoperative days for an incidence of 0.7%. The mortality rate among these patients was 36%. The only recognizable predisposing factor was relief of high-grade carotid...

    journal_title:Journal of vascular surgery

    pub_type: 杂志文章


    authors: Pomposelli FB,Lamparello PJ,Riles TS,Craighead CC,Giangola G,Imparato AM

    更新日期:1988-02-01 00:00:00

  • Transforming growth factor β neutralization finely tunes macrophage phenotype in elastase-induced abdominal aortic aneurysm and is associated with an increase of arginase 1 expression in the aorta.

    abstract:OBJECTIVE:Macrophages play a critical role in the initiation and progression of abdominal aortic aneurysm (AAA) and are classically distinguished into M1 "proinflammatory" and M2 "anti-inflammatory" macrophages. Topical application of elastase associated with transforming growth factor β (TGF-β) systemic neutralization...

    journal_title:Journal of vascular surgery

    pub_type: 杂志文章


    authors: Raffort J,Lareyre F,Clément M,Moratal C,Jean-Baptiste E,Hassen-Khodja R,Burel-Vandenbos F,Bruneval P,Chinetti G,Mallat Z

    更新日期:2019-08-01 00:00:00

  • Acute reductions in mechanical wall strain precede the formation of intimal hyperplasia in a murine model of arterial occlusive disease.

    abstract:OBJECTIVE:Intimal hyperplasia (IH) continues to plague the durability of vascular interventions. Employing a validated murine model, ultrasound biomicroscopy, and speckle-tracking algorithms, we tested the hypothesis that reduced cyclic arterial wall strain results in accentuated arterial wall IH. METHODS:A 9-0 suture...

    journal_title:Journal of vascular surgery

    pub_type: 杂志文章


    authors: Favreau JT,Liu C,Yu P,Tao M,Mauro C,Gaudette GR,Ozaki CK

    更新日期:2014-11-01 00:00:00

  • Open surgery for chronic dissection.

    abstract::Chronic aortic dissection is one of the most challenging pathologies faced by aortic surgeons. The variety of presentations and the multiple comorbidities of the patients make treatment and follow-up a subject of much debate. Historical data is difficult to interpret because of the heterogeneity of the included popula...

    journal_title:Journal of vascular surgery

    pub_type: 杂志文章,评审


    authors: Constantinou J,Kelay A,Mastracci TM

    更新日期:2016-05-01 00:00:00

  • Initial experience and outcome of a new hemodialysis access device for catheter-dependent patients.

    abstract:OBJECTIVE:The effects of a new long-term subcutaneous vascular access device were studied in access-challenged patients who were poor candidates for fistulas or grafts due to venous obstruction. Bacteremia rates, patency, and function of the Hemodialysis Reliable Outflow (HeRO) Vascular Access Device (Hemosphere Inc, M...

    journal_title:Journal of vascular surgery

    pub_type: 临床试验,杂志文章,多中心研究


    authors: Katzman HE,McLafferty RB,Ross JR,Glickman MH,Peden EK,Lawson JH

    更新日期:2009-09-01 00:00:00

  • Percutaneous transluminal angioplasty and stenting as first-choice treatment in patients with chronic mesenteric ischemia.

    abstract:PURPOSE:Open revascularization in patients with chronic mesenteric ischemia (CMI) is considered the gold standard. Percutaneous transluminal angioplasty and stenting (PTAS) is often reserved for patients not suitable for open revascularization. In our institute, endovascular revascularization is the first-choice treatm...

    journal_title:Journal of vascular surgery

    pub_type: 杂志文章


    authors: Fioole B,van de Rest HJ,Meijer JR,van Leersum M,van Koeverden S,Moll FL,van den Berg JC,de Vries JP

    更新日期:2010-02-01 00:00:00

  • Predictors of neck bleeding after eversion carotid endarterectomy.

    abstract:OBJECTIVE:The aim of this study was to identify predictors for neck bleeding after eversion carotid endarterectomy (eCEA). METHODS:A prospectively compiled computerized database of all primary eCEAs performed at a tertiary referral center between September 1998 and December 2009 was analyzed. The end point was any nec...

    journal_title:Journal of vascular surgery

    pub_type: 杂志文章


    authors: Baracchini C,Gruppo M,Mazzalai F,Lorenzetti R,Meneghetti G,Ballotta E

    更新日期:2011-09-01 00:00:00

  • Off-the-shelf multibranched endograft for total endovascular repair of the aortic arch.

    abstract:OBJECTIVE:The goal of this study was to select branched endograft designs that could fit most aortic arch anatomies. Such off-the-shelf endografts, once available, would be an endovascular therapeutic option to consider in the acute setting and would shorten the design and manufacturing process. METHODS:We retrospecti...

    journal_title:Journal of vascular surgery

    pub_type: 杂志文章,多中心研究


    authors: Bosse C,Kölbel T,Mougin J,Kratzberg J,Fabre D,Haulon S

    更新日期:2020-09-01 00:00:00