Structure-property relationships for wet dentin adhesive polymers.


:Dentin adhesive systems for composite tooth restorations are composed of hydrophilic/hydrophobic monomers, solvents, and photoinitiators. The adhesives undergo phase separation and concomitant compositional change during their application in the wet oral environment; phase separation compromises the quality of the hybrid layer in the adhesive/dentin interface. In this work, the adhesive composition in the hybrid layer can be represented using the phase boundaries of a ternary phase diagram for the hydrophobic monomer/hydrophilic monomer/water system. The polymer phases, previously unaccounted for, play an important role in determining the mechanical behavior of the bulk adhesive, and the chemomechanical properties of the phases are intimately related to the effects produced by differences in the hydrophobic-hydrophilic composition. As the composition of the polymer phases varies from hydrophobic-rich to hydrophilic-rich, the amount of the adsorbed water and the nature of polymer-water interaction vary nonlinearly and strongly correlate with the change in elastic moduli under wet conditions. The failure strain, loss modulus, and glass transition temperature vary nonmonotonically with composition and are explained based upon primary and secondary transitions observed in dynamic mechanical testing. Due to the variability in composition, the assignment of mechanical properties and the choice of suitable constitutive models for polymer phases in the hybrid layer are not straightforward. This work investigates the relationship between composition and chemomechanical properties of the polymer phases formed on the water-adhesive phase boundary using quasistatic and dynamic mechanical testing, mass transfer experiments, and vibrational spectroscopy.






Parthasarathy R,Misra A,Song L,Ye Q,Spencer P




Has Abstract


2018-12-17 00:00:00












  • Lateral field excited quartz crystal microbalances for biosensing applications.

    abstract::The most common bulk acoustic wave device used in biosensing applications is the quartz crystal microbalance (QCM), in which a resonant pure shear acoustic wave is excited via electrodes on both major faces of a thin AT-cut quartz plate. For biosensing, the QCM is used to detect the capture of a target by a target-cap...


    pub_type: 杂志文章


    authors: Hartz JSR,Emanetoglu NW,Howell C,Vetelino JF

    更新日期:2020-06-02 00:00:00

  • Influence of multiscale and curved structures on the migration of stem cells.

    abstract::Understanding how topographical cues can control cell behavior is a major fundamental question which is of particular interest for implant design. Recent findings show that cell-scale curvature, as well as nanoscale topography, can affect different aspects of cell migration. However, the correlation between specific c...


    pub_type: 杂志文章


    authors: Belaud V,Petithory T,Ponche A,Mauclair C,Donnet C,Pieuchot L,Benayoun S,Anselme K

    更新日期:2018-12-31 00:00:00

  • Study of nucleic acid-gold nanorod interactions and detecting nucleic acid hybridization using gold nanorod solutions in the presence of sodium citrate.

    abstract::In this study, the authors report that sodium citrate can aggregate hexadecyl-trimethyl-ammonium ion(+)-coated gold nanorods (AuNRs), and nucleic acids of different charge and structure properties, i.e., single-stranded DNA (ssDNA), double-stranded DNA (dsDNA), single-stranded peptide nucleic acid (PNA), and PNA-DNA c...


    pub_type: 杂志文章


    authors: Kanjanawarut R,Su X

    更新日期:2010-09-01 00:00:00

  • Protein adsorption to poly(tetrafluoroethylene) membranes modified with grafted poly(acrylic acid) chains.

    abstract::Protein adsorption to biomaterial surfaces is important for the function of such materials with anchorage-dependent cell adhesion requiring the presence of adsorbed proteins. The current study evaluated five solid surfaces with poly(acrylic acid) (PAA) grafted from the surface of a poly(tetrafluoroethylene) membrane w...


    pub_type: 杂志文章


    authors: Mohd Hidzir N,A A,Kępa K,Hill DJT,Jorgensen L,Grøndahl L

    更新日期:2020-06-11 00:00:00

  • Micro- and nanostructured poly[oligo(ethylene glycol)methacrylate] brushes grown from photopatterned halogen initiators by atom transfer radical polymerization.

    abstract::Photolithographic techniques have been used to fabricate polymer brush micro- and nanostructures. On exposure to UV light with a wavelength of 244 nm, halogens were selectively removed from films of chloromethylphenyltrichlorosilane and 3-(2-bromoisobutyramido)propyl-triethoxysilane on silicon dioxide. Patterning was ...


    pub_type: 杂志文章


    authors: Ahmad SA,Leggett GJ,Hucknall A,Chilkoti A

    更新日期:2011-03-01 00:00:00

  • To be a radical or not to be one? The fate of the stable nitroxide radical TEMPO [(2,2,6,6-Tetramethylpiperidin-1-yl)oxyl] undergoing plasma polymerization into thin-film coatings.

    abstract::The stable nitroxide radical TEMPO [(2,2,6,6-Tetramethylpiperidin-1-yl)oxyl] has a multitude of applications in fields ranging from energy storage to biomedical applications and many more. However, to date, the processes of incorporating nitroxide radicals into thin-film coatings are laborious and not cost-effective, ...


    pub_type: 杂志文章


    authors: Michl TD,Tran DTT,Böttle K,Kuckling HF,Zhalgasbaikyzy A,Ivanovská B,Cavallaro AA,Araque Toledo MA,Sherman PJ,Al-Bataineh SA,Vasilev K

    更新日期:2020-06-26 00:00:00

  • ToF-SIMS analysis of osteoblast-like cells and their mineralized extracellular matrix on strontium enriched bone cements.

    abstract::Commonly used implants for therapeutic approaches of non-systemically impaired bone do not sufficiently support the healing process of osteoporotic bone. Since strontium (II) has been proven as an effective anti-osteoporotic drug new types of strontium enriched calcium phosphate bone cements were developed. As osteopo...


    pub_type: 杂志文章


    authors: Kokesch-Himmelreich J,Schumacher M,Rohnke M,Gelinsky M,Janek J

    更新日期:2013-12-01 00:00:00

  • Immobilization of inorganic pyrophosphatase on nanodiamond particles retaining its high enzymatic activity.

    abstract::Nanodiamond (ND) particles are popular platforms for the immobilization of molecular species. In the present research, enzyme Escherichia coli inorganic pyrophosphatase (PPase) was immobilized on detonation ND through covalent or noncovalent bonding and its enzymatic activity was characterized. Factors affecting adsor...


    pub_type: 杂志文章


    authors: Rodina EV,Valueva AV,Yakovlev RY,Vorobyeva NN,Kulakova II,Lisichkin GV,Leonidov NB

    更新日期:2015-12-21 00:00:00

  • Mixed DNA/oligo(ethylene glycol) functionalized gold surfaces improve DNA hybridization in complex media.

    abstract::Reliable, direct "sample-to-answer" capture of nucleic acid targets from complex media would greatly improve existing capabilities of DNA microarrays and biosensors. This goal has proven elusive for many current nucleic acid detection technologies attempting to produce assay results directly from complex real-world sa...


    pub_type: 杂志文章


    authors: Lee CY,Gamble LJ,Grainger DW,Castner DG

    更新日期:2006-06-01 00:00:00

  • Time-of-flight secondary ion mass spectrometry analyses of vancomycin.

    abstract::As an antibiotic that prevents and treats infections caused by Gram-positive bacteria such as Staphylococcus aureus, vancomycin incorporated in a biodegradable polymer poly(lactide-co-glycolide) provides opportunities to construct controlled-release drug delivery systems. Developments associated with this promising sy...


    pub_type: 杂志文章


    authors: Du L,Yang X,Li W,Li H,Feng S,Zeng R,Yu B,Xiao L,Liu Y,Tu M,Nie HY

    更新日期:2018-01-10 00:00:00

  • Time of flight secondary ion mass spectrometry surface and in-depth study of degradation of nanosheet poly(L-lactic acid) films.

    abstract::With the advent of novel fabrication technologies, free-standing poly(l-lactic acid) (PLLA) nanosheets have been shown to have enhanced performance over their micro- or macroscale equivalents as tissue engineering and drug delivery constructs. In the present research, the authors investigated the surface degradation b...


    pub_type: 杂志文章


    authors: Marchany MD,Gardella JA Jr,Kuchera TJ

    更新日期:2015-03-20 00:00:00

  • Investigations on the secondary structure of polypeptide chains in polyelectrolyte multilayers and their effect on the adhesion and spreading of osteoblasts.

    abstract::Inspired by the composition of the native extracellular matrix, biomimetic polyelectrolyte multilayers were assembled from polypeptides and the glycosaminoglycan chondroitin sulfate (CS). To investigate whether peptide conformation imposes an effect on the cell biological functions of osteoblasts, the secondary struct...


    pub_type: 杂志文章


    authors: Grohmann S,Rothe H,Liefeith K

    更新日期:2012-12-01 00:00:00

  • X-ray spectromicroscopy of nanoparticulate iron oxide phases.

    abstract::Soft x-ray spectromicroscopy techniques have seen great amount of development in the recent years, and with the development of new diffraction limited synchrotron source, many new nanoscale and mesoscale characterization opportunities of applied materials are foreseen. In this perspective, the authors present some exa...


    pub_type: 杂志文章


    authors: Dietrich PM,Unger WE,Swaraj S

    更新日期:2016-10-28 00:00:00

  • Neutron study of phospholipids 1-palmitoyl-2-oleoyl-sn-glycero-3-phospho-ethanolamine spray coating on titanium implants.

    abstract::Permanent implants made from titanium are widely used and successfully implemented in medicine to address problems related to orthopedic and oral disorders. However, implants that interact in all cases optimally and durably with bone tissue have yet to be developed. Here, the authors suggest a phospholipids 1-palmitoy...


    pub_type: 杂志文章


    authors: Golub M,Lott D,Garamus VM,Laipple D,Stoermer M,Watkins EB,Schreyer A,Willumeit-Römer R

    更新日期:2015-03-29 00:00:00

  • Self-patterning of adipose-derived mesenchymal stem cells and chondrocytes cocultured on hyaluronan-grafted chitosan surface.

    abstract::The articular cartilage, once injured, has a limited capacity for intrinsic repair. Preparation of functionally biocartilage substitutes in vitro for cartilage repair is an attractive concept with the recent advances in tissue engineering. In this study, adipose-derived adult stem cells (ADAS) and chondrocytes (Ch) we...


    pub_type: 杂志文章


    authors: Yeh HY,Hsieh FY,Hsu SH

    更新日期:2016-03-25 00:00:00

  • Enhanced osteoblast differentiation on scaffolds coated with TiO2 compared to SiO2 and CaP coatings.

    abstract::The aim was to compare the protein release from normal human osteoblasts (NHO) cultured on scaffolds with similar morphology but different coatings. Different ceramic coatings; TiO(2), SiO(2) and calcium phosphate (CaP); Ca(9)HPO(4)(PO(4))(5)OH, were applied to porous TiO(2) scaffolds prepared by polymer sponge replic...


    pub_type: 杂志文章


    authors: Verket A,Tiainen H,Haugen HJ,Lyngstadaas SP,Nilsen O,Reseland JE

    更新日期:2012-12-01 00:00:00

  • Lipid analysis of eight human breast cancer cell lines with ToF-SIMS.

    abstract::In this work, four triple negative (TN) cell lines, three ER+ and PR+ receptor positive (RP) cell lines, and one ER+, PR+, and HER2+ cell line were chemically distinguished from one another using time-of-flight secondary ion mass spectrometry (ToF-SIMS) and principal component analysis (PCA). PCA scores separation was...


    pub_type: 杂志文章


    authors: Robinson MA,Graham DJ,Morrish F,Hockenbery D,Gamble LJ

    更新日期:2015-06-28 00:00:00

  • Synthesis and characterization of tethered lipid assemblies for membrane protein reconstitution (Review).

    abstract::Biological membranes and their related molecular mechanisms are essential for all living organisms. Membranes host numerous proteins and are responsible for the exchange of molecules and ions, cell signaling, and cell compartmentation. Indeed, the plasma membrane delimits the intracellular compartment from the extrace...


    pub_type: 杂志文章,评审


    authors: Veneziano R,Rossi C,Chenal A,Brenner C,Ladant D,Chopineau J

    更新日期:2017-09-28 00:00:00

  • Effect of calcium on the microstructure and corrosion behavior of microarc oxidized Mg-xCa alloys.

    abstract::Magnesium alloys are potential biodegradable implants for biomedical applications, and calcium (Ca) is one kind of ideal element being examined for magnesium alloys and biodegradable ceramic coatings owing to its biocompatibility and mechanical suitability. In this study, microarc oxidation (MAO) coatings were prepare...


    pub_type: 杂志文章


    authors: Pan Y,Chen C,Feng R,Cui H,Gong B,Zheng T,Ji Y

    更新日期:2018-01-16 00:00:00

  • Membrane composition-mediated protein-protein interactions.

    abstract::The authors investigate membrane composition-mediated interactions between proteins adsorbed onto a two-component lipid bilayer close to critical demixing using coarse-grained molecular dynamics simulations and a phenomenological Ginzburg-Landau theory. The simulations consist of three-bead lipids and platelike protei...


    pub_type: 杂志文章


    authors: Reynwar BJ,Deserno M

    更新日期:2008-06-01 00:00:00

  • Carbon nanodots: Opportunities and limitations to study their biodistribution at the human lung epithelial tissue barrier.

    abstract::Inhalation of combustion-derived ultrafine particles (≤0.1 μm) has been found to be associated with pulmonary and cardiovascular diseases. However, correlation of the physicochemical properties of carbon-based particles such as surface charge and agglomeration state with adverse health effects has not yet been establi...


    pub_type: 杂志文章


    authors: Durantie E,Barosova H,Drasler B,Rodriguez-Lorenzo L,Urban DA,Vanhecke D,Septiadi D,Hirschi-Ackermann L,Petri-Fink A,Rothen-Rutishauser B

    更新日期:2018-09-11 00:00:00

  • Coated nanodiamonds interact with tubulin beta-III negative cells of adult brain tissue.

    abstract::Fluorescent nanodiamonds (NDs) coated with therapeutics and cell-targeting structures serve as effective tools for drug delivery. However, NDs circulating in blood can eventually interact with the blood-brain barrier, resulting in undesired pathology. Here, we aimed to detect interaction between NDs and adult brain ti...


    pub_type: 杂志文章


    authors: Šimková V,Freislebenová H,Neuhöferová E,Petráková V,Amini A,Benson V

    更新日期:2020-12-03 00:00:00

  • ToF-SIMS and laser-SNMS analysis of Madin-Darby canine kidney II cells with silver nanoparticles using an argon cluster ion beam.

    abstract::The use of nanoparticles is one of the fastest expanding fields in industrial as well as in medical applications, owing to their remarkable characteristics. Silver nanoparticles (AgNPs) are among the most-commercialized nanoparticles because of their antibacterial effects. Laser postionization secondary neutral mass s...


    pub_type: 杂志文章


    authors: Nees R,Pelster A,Körsgen M,Jungnickel H,Luch A,Galla HJ,Arlinghaus HF

    更新日期:2015-06-15 00:00:00

  • Science and engineering of nanodiamond particle surfaces for biological applications (Review).

    abstract::Diamond has outstanding bulk properties such as super hardness, chemical inertness, biocompatibility, luminescence, to name just a few. In the nanoworld, in order to exploit these outstanding bulk properties, the surfaces of nanodiamond (ND) particles must be accordingly engineered for specific applications. Modificat...


    pub_type: 杂志文章,评审


    authors: Shenderova OA,McGuire GE

    更新日期:2015-09-05 00:00:00

  • Photonic biosensor based on photocorrosion of GaAs/AlGaAs quantum heterostructures for detection of Legionella pneumophila.

    abstract::Photocorrosion of semiconductors is strongly sensitive to the presence of surface states, and it could be influenced by electrically charged molecules immobilized near the semiconductor/electrolyte interface. The underlying mechanism is related to band bending of the semiconductor structure near the surface and the as...


    pub_type: 杂志文章


    authors: Aziziyan MR,Hassen WM,Morris D,Frost EH,Dubowski JJ

    更新日期:2016-03-22 00:00:00

  • Selective immobilization of biomolecules onto an activated polymeric adlayer.

    abstract::The authors report a facile method for the selective immobilization of biomolecules onto a gold surface that was preactivated by a polymeric adlayer. The polymeric adlayer was designed to perform triple functions: high resistance to nonspecific protein adsorption, efficient surface anchoring, and subsequent covalent a...


    pub_type: 杂志文章


    authors: Lee BS,Park S,Lee KB,Jon S,Choi IS

    更新日期:2007-12-01 00:00:00

  • Astrocyte spreading and migration on aggrecan-laminin dot gradients.

    abstract::The surface concentration gradient of two extracellular matrix (ECM) macromolecules was developed to study the migratory and morphological responses of astrocytes to molecular cues typically found in the central nervous system injury environment. The gradient, prepared using microcontact printing, was composed of rand...


    pub_type: 杂志文章


    authors: Hsiao TW,Tresco PA,Hlady V

    更新日期:2017-09-11 00:00:00

  • Burr-like, laser-made 3D microscaffolds for tissue spheroid encagement.

    abstract::The modeling, fabrication, cell loading, and mechanical and in vitro biological testing of biomimetic, interlockable, laser-made, concentric 3D scaffolds are presented. The scaffolds are made by multiphoton polymerization of an organic-inorganic zirconium silicate. Their mechanical properties are theoretically modeled...


    pub_type: 杂志文章


    authors: Danilevicius P,Rezende RA,Pereira FD,Selimis A,Kasyanov V,Noritomi PY,da Silva JV,Chatzinikolaidou M,Farsari M,Mironov V

    更新日期:2015-06-23 00:00:00

  • Platelets and coronary artery disease: Interactions with the blood vessel wall and cardiovascular devices.

    abstract::In view of the rare presence of studies concerning platelet function as risk factor in atherosclerotic patients, processes underlying thromboembolic events are reviewed in this paper. The morphology and the structural organization-membrane receptors, the open canalicular and dense tubular systems, the cytoskeleton, mi...


    pub_type: 杂志文章,评审


    authors: Reinthaler M,Braune S,Lendlein A,Landmesser U,Jung F

    更新日期:2016-06-08 00:00:00

  • Immobilized laminin concentration gradients on electrospun fiber scaffolds for controlled neurite outgrowth.

    abstract::Neuronal process growth is guided by extrinsic environmental cues such as extracellular matrix (ECM) proteins. Recent reports have described that the growth cone extension is superior across gradients of the ECM protein laminin compared to growth across uniformly distributed laminin. In this work, the authors have pre...


    pub_type: 杂志文章


    authors: Zander NE,Beebe TP Jr

    更新日期:2014-03-01 00:00:00