Genitourinary melioidosis: a descriptive study.

Abstract:

:Melioidosis is the disease caused by the soil and water bacterium, Burkholderia pseudomallei. Our study aimed to delineate its genitourinary manifestations. Over a 10-year period (2006-2016), 20 adults with culture-confirmed genitourinary melioidosis were identified. The patients were all men with a mean age of 45.3 ± 12.3 years. The common risk factors were diabetes mellitus (65%) and alcoholism (25%); a majority of patients (90%) had chronic melioidosis. Most had disseminated disease (n = 17) and 55% were bacteraemic. The prostate was the organ most frequently involved (60%, n = 12), followed by the kidney, bladder and seminal vesicles. Diagnosis was established by blood and urine cultures and imaging. Patients were successfully treated with ceftazidime intensive therapy followed by eradicative therapy, with surgical debridement and guided aspiration, when deemed necessary. There was one case fatality and no relapses. Melioidosis is an important differential to be considered in chronic genitourinary infections in the appropriate setting.

journal_name

Trop Doct

journal_title

Tropical doctor

authors

Koshy M,Sadanshiv P,Sathyendra S

doi

10.1177/0049475518817416

subject

Has Abstract

pub_date

2019-04-01 00:00:00

pages

104-107

issue

2

eissn

0049-4755

issn

1758-1133

journal_volume

49

pub_type

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