Abstract：
BACKGROUND:To investigate the clinical values of serum melatonin and αII spectrin cleavage products (SBDPs) in assessing the severity of brain injury in preterm infants. METHODS:Sixty-four premature infants in total were selected and classified into the brain injury group (BI, n = 30) and the non-brain injury group (CON, n = 34) according to cranial imaging examination. The serum melatonin and SBDPs were detected by ELISA. All the preterm infants were received NBNA testing at 40 weeks of corrected gestational age. RESULTS:The levels of melatonin and SBDPs in the BI group were significantly higher than the CON group (p < 0.05) and the levels in the infants with severe brain injury were significantly higher than those with mild brain injury (p < 0.05), as well as exhibiting a negative correlation with the NBNA score at 40 weeks of corrected gestational age (p < 0.05). CONCLUSIONS:Detecting melatonin and SBDPs has clinical value in diagnosing and assessing the severity of brain injury in preterm infants.
journal_name
Pediatr Neonatoljournal_title
Pediatrics and neonatologyauthors
Yan C,Zhang Bdoi
10.1016/j.pedneo.2018.11.005subject
Has Abstractpub_date
2019-08-01 00:00:00pages
435-440issue
4eissn
1875-9572issn
2212-1692pii
S1875-9572(18)30387-5journal_volume
60pub_type
杂志文章abstract：:Respiratory distress syndrome (RDS) was recognized to be caused by primary surfactant deficiency almost 70 years ago and continuous positive airway pressure was introduced approximately 50 years ago. Since then, there have been many developments in neonatology; we know many things but others are still controversial. T...
journal_title：Pediatrics and neonatology
pub_type： 杂志文章
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journal_title：Pediatrics and neonatology
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journal_title：Pediatrics and neonatology
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journal_title：Pediatrics and neonatology
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journal_title：Pediatrics and neonatology
pub_type： 杂志文章
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journal_title：Pediatrics and neonatology
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journal_title：Pediatrics and neonatology
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journal_title：Pediatrics and neonatology
pub_type： 杂志文章,meta分析
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journal_title：Pediatrics and neonatology
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journal_title：Pediatrics and neonatology
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journal_title：Pediatrics and neonatology
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journal_title：Pediatrics and neonatology
pub_type： 杂志文章
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journal_title：Pediatrics and neonatology
pub_type： 杂志文章
doi：10.1016/j.pedneo.2020.02.005
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journal_title：Pediatrics and neonatology
pub_type： 杂志文章,评审
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journal_title：Pediatrics and neonatology
pub_type： 杂志文章
doi：10.1016/j.pedneo.2012.06.003
更新日期：2012-08-01 00:00:00
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journal_title：Pediatrics and neonatology
pub_type： 杂志文章
doi：10.1016/j.pedneo.2013.06.009
更新日期：2016-04-01 00:00:00
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journal_title：Pediatrics and neonatology
pub_type： 杂志文章
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journal_title：Pediatrics and neonatology
pub_type： 杂志文章,评审
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journal_title：Pediatrics and neonatology
pub_type： 杂志文章,评审
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journal_title：Pediatrics and neonatology
pub_type： 杂志文章
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journal_title：Pediatrics and neonatology
pub_type： 杂志文章
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journal_title：Pediatrics and neonatology
pub_type： 杂志文章
doi：10.1016/j.pedneo.2014.06.006
更新日期：2015-04-01 00:00:00
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journal_title：Pediatrics and neonatology
pub_type： 杂志文章,评审
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journal_title：Pediatrics and neonatology
pub_type： 杂志文章
doi：10.1016/j.pedneo.2013.10.009
更新日期：2014-08-01 00:00:00
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journal_title：Pediatrics and neonatology
pub_type： 杂志文章
doi：10.1016/j.pedneo.2016.08.010
更新日期：2017-10-01 00:00:00
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journal_title：Pediatrics and neonatology
pub_type： 杂志文章
doi：10.1016/j.pedneo.2014.01.004
更新日期：2014-12-01 00:00:00
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journal_title：Pediatrics and neonatology
pub_type： 杂志文章
doi：10.1016/j.pedneo.2010.12.004
更新日期：2011-02-01 00:00:00
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journal_title：Pediatrics and neonatology
pub_type： 杂志文章,评审
doi：10.1016/j.pedneo.2015.08.005
更新日期：2016-04-01 00:00:00
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journal_title：Pediatrics and neonatology
pub_type： 杂志文章
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更新日期：2012-02-01 00:00:00
