Short-Term Assessment of Intravitreal Dexamethasone Implant Using Enhanced-Depth Image Optical Coherence Tomography and Optical Coherence Tomography Angiography in Patients with Retinal Vascular Diseases.

abstract：INTRODUCTION:Clinical guidelines recommend levothyroxine as the standard of care for hypothyroidism and that patients should be treated with a consistent preparation of synthetic levothyroxine without switching among formulations. This study examines the likelihoods of negative clinical outcomes between continuous user...

journal_title：Advances in therapy

authors： Hennessey JV,Espaillat R,Duan Y,Soni-Brahmbhatt S,Lage MJ,Singer P

更新日期：2020-10-28 00:00:00

abstract：INTRODUCTION:Endometriosis symptoms are nonspecific and overlap with other gynecologic and gastrointestinal diseases, leading to long diagnostic delays. The burden of endometriosis has been documented; however, little is known about the impact of diagnostic delays on healthcare costs leading up to diagnoses. The purpos...

journal_title：Advances in therapy

authors： Surrey E,Soliman AM,Trenz H,Blauer-Peterson C,Sluis A

更新日期：2020-03-01 00:00:00

abstract：INTRODUCTION:Wet age-related macular degeneration (AMD) is a chronic eye condition that causes severe deterioration of vision and even blindness. Current wet AMD treatment in the UK involves the vascular endothelial growth factor inhibitors ranibizumab and aflibercept. Patients with wet AMD require frequent and long-te...

journal_title：Advances in therapy

authors： Ghosh W,Wickstead R,Claxton L,Kusel J,Taylor M,Fleetwood K,Pulikottil-Jacob R

更新日期：2016-09-01 00:00:00

abstract：:This prospective study was performed to determine whether gentamicin can be prescribed routinely to patients with spinal cord injury undergoing urologic procedures, or whether antibiotic therapy must be selected on the basis of recent urine microbiologic test results. Between January 2004 and June 2005, procedures wer...

journal_title：Advances in therapy

authors： Vaidyanathan S,Soni BM

更新日期：2006-01-01 00:00:00

abstract：:In an open, uncontrolled study, 105 patients with locomotor system symptoms were treated twice daily with an ointment containing a Symphytum active substance complex. A clear therapeutic effect was noted on chronic and subacute symptoms that were accompanied mainly by functional disturbances and pain in the musculatur...

journal_title：Advances in therapy

authors： Kucera M,Kálal J,Polesná Z

更新日期：2000-07-01 00:00:00

abstract：INTRODUCTION:This clinical study aimed to investigate the effect of brinzolamide, a topical carbonic anhydrase inhibitor, on corneal endothelial cells (CECs) in patients with glaucoma using a follow-up clinical study design. METHODS:Patients with primary open-angle glaucoma or ocular hypertension were administrated an...

journal_title：Advances in therapy

authors： Nakano T,Inoue R,Kimura T,Suzumura H,Tanino T,Yamazaki Y,Yoshikawa K,Tatemichi M

更新日期：2016-08-01 00:00:00

abstract：INTRODUCTION:Ample evidence suggested a role of sigma-1 receptor in affective disorders since the interaction of numerous antidepressants with sigma receptors was discovered. A recent study on Japanese subjects found a genetic variant within the encoding gene SIGMAR1 (rs1800866A>C) associated with major depressive diso...

journal_title：Advances in therapy

authors： Mandelli L,Wang SM,Han C,Lee SJ,Patkar AA,Masand PS,Pae CU,Serretti A

更新日期：2017-03-01 00:00:00

abstract：:This interventional study was undertaken to assess the impact of physiotherapy education on the knowledge and attitudes of physiotherapists (PTs) and physiotherapy students (PSs) toward euthanasia. The study, which was conducted during the period between 2004 and 2005, included a total of 494 participants (311 PTs; 18...

journal_title：Advances in therapy

authors： Cavlak U,Aslan UB,Gurso S,Yagci N,Yeldan I

更新日期：2007-01-01 00:00:00

abstract：INTRODUCTION:This analysis of pooled data from four randomized, controlled-dose adjustment, phase 3 studies (three 15-week, double-blind, placebo- and active-controlled studies and a 1-year, open-label, active-controlled safety study) in patients with chronic osteoarthritis hip or knee pain or low back pain evaluated t...

journal_title：Advances in therapy

authors： Etropolski M,Kuperwasser B,Flügel M,Häufel T,Lange B,Rauschkolb C,Laschewski F

更新日期：2014-06-01 00:00:00

abstract：:Subretinal hemorrhage secondary to age-related macular degeneration (AMD) has a poor visual prognosis. Surgical drainage of the blood improves visual acuity only in selected patients. We report on two elderly patients with spontaneous subretinal hemorrhage from AMD. In one eye, recombinant tissue plasminogen activator...

journal_title：Advances in therapy

authors： Hesse L,Kroll P

更新日期：1997-09-01 00:00:00

abstract：:Cases are presented to illustrate pitfalls in radiologic and histopathologic diagnosis in urology. In a 73-year-old woman, ultrasound revealed calcification in an irregular mass arising from the left wall of the bladder. Bladder biopsy reported the mass as papillary transitional cell carcinoma. Histologically, the spe...

journal_title：Advances in therapy

authors： Vaidyanathan S,Soni BM,Hughes PL,Mansour P,Singh G

更新日期：2006-11-01 00:00:00

abstract：INTRODUCTION:This study aims to evaluate the early predictive value for postoperative sepsis and 30-day mortality in liver transplant patients using sequential organ failure assessment (SOFA). METHODS:A total of 96 liver transplant patients were enrolled into this study from February 2015 to June 2018. The general inf...

journal_title：Advances in therapy

authors： Wang XW,Niu XG,Li JX,Zhang SS,Jiao XF

更新日期：2019-03-01 00:00:00

abstract：:Alpha-mannosidosis is a rare lysosomal storage disorder that generally presents in early childhood. It is a progressive, highly heterogeneous disease that is difficult to recognize, and a diagnosis is usually reached after referrals to multiple specialists. It is important to understand the challenges faced by patient...

journal_title：Advances in therapy

authors： Verrecchia E,Sicignano LL,Massaro MG,Rocco R,Silvestri G,Rossi S,Manna R

更新日期：2020-11-24 00:00:00

abstract：:With the increasing availability of biosimilars, the practice of switching therapies for non-medical reasons between an originator biologic and an analogous biosimilar has become more common. The evidence to support this practice mostly comes from single-switch randomized controlled trials (RCTs) and real-world (RW) e...

journal_title：Advances in therapy

authors： Feagan BG,Marabani M,Wu JJ,Faccin F,Spronk C,Castañeda-Hernández G

更新日期：2020-11-01 00:00:00

abstract：:The prognosis for patients with rheumatoid arthritis or spondyloarthritides has improved dramatically due to earlier diagnosis, recognition of the need to treat early with conventional synthetic disease-modifying antirheumatic drugs (csDMARDs), alone or in combinations, the establishment of treatment targets, and the ...

journal_title：Advances in therapy

authors： Govoni M,Bortoluzzi A,Lo Monaco A,Adami S,Addimanda O,Caimmi C,De Vita S,Ferri C,Manfredi A,Orsolini G,Possemato N,Quartuccio L,Salvarani C,Zabotti A,Rossini M

更新日期：2014-08-01 00:00:00

abstract：:Endophthalmitis is an intraocular inflammatory condition which may or may not be caused by infective agents. Noninfectious (sterile) endophthalmitis may be attributable to various causes including postoperative retained soft lens matter or toxicity following introduction of other agents into the eye. Infectious endoph...

journal_title：Advances in therapy

authors： Tranos P,Dervenis N,Vakalis AN,Asteriadis S,Stavrakas P,Konstas AG

更新日期：2016-05-01 00:00:00

abstract：:Brucellosis remains an important public health problem in Turkey, just as it is in other regions of the world. This study was conducted to determine the types and rates of cutaneous lesions that occur in patients with brucellosis. Brucellosis was diagnosed by standard tube agglutination testing for Brucella antibodies...

journal_title：Advances in therapy

authors： Akcali C,Savas L,Baba M,Turunc T,Seckin D

更新日期：2007-07-01 00:00:00

abstract：:In the original article, under the "Access to treatment" heading. ...

journal_title：Advances in therapy

authors： Rezk MF,Pieper B

更新日期：2020-11-01 00:00:00

abstract：INTRODUCTION:The purpose of this study was to determine prescribing trends in a specialist glaucoma clinic in the UK. Specifically, the aims were to determine which drugs were prescribed as first-, second-, and third-line treatment, the persistence of first-, second-, and third-line treatment regimens, and the proporti...

journal_title：Advances in therapy

authors： Fajgenbaum M,Ansari E

更新日期：2017-08-01 00:00:00

abstract：:There has been increased interest in gout in both academic and clinical practice settings. Several reasons may explain this. The prevalence of both hyperuricemia and gout has risen in the last decades in developed countries and therefore the burden of gout has increased. The association of hyperuricemia and gout with ...

journal_title：Advances in therapy

authors： Perez-Ruiz F,Dalbeth N,Bardin T

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:The OPTIMA© (MSD, Courbevoie, France) questionnaire was developed to promote shared decisions and the set-up of specific micro-objectives in clinical practice by optimizing communication between type 2 diabetes (T2DM) patients and their physicians. The present study aimed to assess OPTIMA in clinical practic...

journal_title：Advances in therapy

authors： Grimaldi A,Penfornis A,Consoli S,Falissard B,Eymard E,Williams P,Dejager S

更新日期：2016-06-01 00:00:00

abstract：INTRODUCTION:This Phase 2 clinical trial assessed the efficacy and safety of the novel antioxidative, renewable compound SkQ1 for topical treatment of dry eye signs and symptoms. METHODS:In a single-center, randomized, double-masked, placebo-controlled, 29-day study, 91 subjects with mild to moderate dry eye instilled...

journal_title：Advances in therapy

authors： Petrov A,Perekhvatova N,Skulachev M,Stein L,Ousler G

更新日期：2016-01-01 00:00:00

abstract：:Multiple, potentially practice-changing cardiology trials have been presented or published over the past year. In this paper, we summarize and place in clinical context, new data regarding management of acute coronary syndrome and ST-elevation myocardial infarction (copeptin assessment, otamixaban, cangrelor, prasugre...

journal_title：Advances in therapy

authors： McNeice AH,McAleavey NM,Menown IB

更新日期：2014-08-01 00:00:00

abstract：OBJECTIVES:This study set out to examine the efficacy and tolerability of two innovative implant forms of leuprorelin acetate in men with advanced hormone-dependent prostate cancer in everyday clinical practice. METHODS:Data were collected from 818 patients (from 273 centers across Germany) who were pretreated with sl...

journal_title：Advances in therapy

authors： Gravel P,Samland D,Löffler M,Maier S,Panozzo M,Muenzberg M

更新日期：2013-03-01 00:00:00

abstract：:Blood pressure lowering by all classes of antihypertensive drugs is accompanied by significant reductions of stroke and major cardiovascular (CV) events. Drugs acting on the renin-angiotensin-aldosterone system, such as angiotensin converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs), showed s...

journal_title：Advances in therapy

authors： Omboni S,Volpe M

更新日期：2019-02-01 00:00:00

abstract：:Chronic constipation (CC) and irritable bowel syndrome with constipation (IBS-C) are common gastrointestinal (GI) disorders. Current treatment options, either prescription or nonprescription medications, have limited efficacy in a subset of patients. There is significant demand for more efficacious medications for the...

journal_title：Advances in therapy

authors： Vazquez-Roque MI,Bouras EP

更新日期：2013-03-01 00:00:00

abstract：INTRODUCTION:In FRESCO (Fruquintinib Efficacy and Safety in 3+ Line Colorectal Cancer Patients) trial, fruquintinib demonstrated a statistically significant and clinically meaningful overall survival benefit in Chinese patients with metastatic colorectal cancer (mCRC). However, its safety profile, including adverse eve...

journal_title：Advances in therapy

authors： Li J,Guo W,Bai Y,Deng Y,Yang L,Chen Z,Zhong H,Xu R,Pan H,Shu Y,Yuan Y,Zhou J,Xu N,Liu T,Ma D,Wu C,Cheng Y,Xu J,Chen D,Li W,Sun S,Yu Z,Cao P,Shen L,Chen H,Wang S,Wang H,Fan S,Guo X,Wang N,Han R

更新日期：2020-11-01 00:00:00

abstract：INTRODUCTION:nab-Paclitaxel plus gemcitabine (nab-P + G) and FOLFIRINOX (FFX) are among the most common first-line (1L) therapies for metastatic adenocarcinoma of the pancreas (MPAC), but real-world data on their comparative effectiveness are limited. METHODS:This retrospective cohort study compared the efficacy and s...

journal_title：Advances in therapy

authors： Kim S,Signorovitch JE,Yang H,Patterson-Lomba O,Xiang CQ,Ung B,Parisi M,Marshall JL

更新日期：2018-10-01 00:00:00

abstract：:In the past 15 years, improvements in the treatment of HIV infection have dramatically reduced morbidity and mortality. Nucleoside reverse transcriptase inhibitors are the backbone of combination antiretroviral therapy for the treatment of HIV. One of the recommended and commonly used therapies in this class is the on...

journal_title：Advances in therapy

authors： Achenbach CJ,Scarsi KK,Murphy RL

更新日期：2010-01-01 00:00:00

abstract：:Coronary heart disease is the major cause of morbidity and mortality in industrialized countries, and its prevalence is predicted to grow as the population ages. Current drugs for chronic stable angina (such as beta-blockers, calcium-channel blockers, long- and short-acting nitrates, and potassium-channel activators) ...

journal_title：Advances in therapy

authors： Prasad UK,Gray D,Purcell H

更新日期：2009-02-01 00:00:00