Integrative/Hybrid Methods Structural Biology: Role of Macromolecular Crystallography.

Abstract:

:Macromolecular crystallography has been central to the emergence and development of structural biology as a scientific discipline. Approximately 90% of the more than 138,000 three-dimensional structures currently available in the Protein Data Bank (PDB) archive, the single, global open access data resource for macromolecular structure data, were determined using X-ray crystallography. MX, the enormous variety of PDB structures of proteins, DNA, and RNA, and computational models derived therefrom will be central to the growth of integrative or hybrid (I/H) methods structural studies of macromolecular assemblies and other complex biological systems.

journal_name

Adv Exp Med Biol

authors

Burley SK

doi

10.1007/978-981-13-2200-6_2

subject

Has Abstract

pub_date

2018-01-01 00:00:00

pages

11-18

eissn

0065-2598

issn

2214-8019

journal_volume

1105

pub_type

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