A Brief Review on the Neuroprotective Mechanisms of Vitexin.

abstract：:We encapsulated tumor necrosis factor-α (TNF-α), a major proinflammatory cytokine, into cholesteryl pullulan (CHP) to prepare TNF/CHP nanoparticles. In this report, we describe the immune-enhancing capability of the nanoparticles to act as a vaccine adjuvant. TNF/CHP nanoparticles showed excellent storage stability an...

journal_title：BioMed research international

authors： Nagatomo D,Taniai M,Ariyasu H,Taniguchi M,Aga M,Ariyasu T,Ohta T,Fukuda S

更新日期：2015-01-01 00:00:00

abstract：:The aim of this study was to develop a vitrification procedure for human ovarian tissue cryopreservation in order to better preserve the ovarian tissue. Large size samples of ovarian tissue retrieved from 15 female-to-male transgender subjects (18-38 years) were vitrified using two solutions (containing propylene glyc...

journal_title：BioMed research international

authors： Fabbri R,Vicenti R,Macciocca M,Pasquinelli G,Paradisi R,Battaglia C,Martino NA,Venturoli S

更新日期：2014-01-01 00:00:00

abstract：:Uraemia and long-term peritoneal dialysis (PD) can lead to fibrotic thickening of the peritoneal membrane, which may limit its dialytic function. Peritoneal fibrosis is associated with the appearance of myofibroblasts and expansion of extracellular matrix. The extent of contribution of resident peritoneal fibroblasts ...

journal_title：BioMed research international

authors： Witowski J,Kawka E,Rudolf A,Jörres A

更新日期：2015-01-01 00:00:00

abstract：:Two fullerene derivatives (fullerenes 1 and 2), bearing a hydrophilic chain on the pyrrolidinic nitrogen, were developed with the aim to deliver anticancer agents to solid tumors. These two compounds showed a significantly different behaviour on human neoplastic cell lines in vitro in respect to healthy leukocytes. In...

journal_title：BioMed research international

authors： Pacor S,Grillo A,Đorđević L,Zorzet S,Lucafò M,Da Ros T,Prato M,Sava G

更新日期：2015-01-01 00:00:00

abstract：:Flash-lamp pulsed-dye laser (FPDL) is a nonablative technology, typically used in vascular malformation therapy due to its specificity for hemoglobin. FPDL treatments were performed in a large group of patients with persistent and/or recalcitrant different dermatological lesions with cutaneous microvessel involvement....

journal_title：BioMed research international

authors： Nisticò S,Campolmi P,Moretti S,Del Duca E,Bruscino N,Conti R,Bassi A,Cannarozzo G

更新日期：2016-01-01 00:00:00

abstract：:There is an emerging body of evidence that chemoresistance and minimal residual disease result from selective resistance of a cell subpopulation from the original tumor that is molecularly and phenotypically distinct. These cells are called "cancer stem cells" (CSCs). In this review, we analyze the potential targeting...

journal_title：BioMed research international

authors： Paldino E,Tesori V,Casalbore P,Gasbarrini A,Puglisi MA

更新日期：2014-01-01 00:00:00

abstract：:To establish a reliable isoproterenol induced heart dysfunction fetal rat model and understand the switches of contractile proteins, 45 pregnant rats were divided into 15 mg/kg-once, 15 mg/kg-twice, sham-operated once, sham-operated twice, and control groups. And 18 adult rats were divided into isoproterenol-treated a...

journal_title：BioMed research international

authors： Li Y,Fang J,Hua Y,Wang C,Mu D,Zhou K

更新日期：2014-01-01 00:00:00

abstract：:Tumourigenesis is a mutation accumulation process, which is likely to start with a mutated founder cell. The evolutionary nature of tumor development makes phylogenetic models suitable for inferring tumor evolution through genetic variation data. Copy number variation (CNV) is the major genetic marker of the genome wi...

journal_title：BioMed research international

authors： Liang Y,Liao B,Zhu W

更新日期：2017-01-01 00:00:00

abstract：Background:The aim of this study was to investigate the potential mechanisms by which chronic unpredictable mild stress (CMS) might induce cardiovascular disease. Methods:Twenty male Sprague-Dawley rats (weighing 180-250 g) were divided into the CMS group (CMS for 3 weeks) and control group (n = 10/group). Sucrose sol...

journal_title：BioMed research international

authors： Liu Z,Liu H,Zeng ZH

更新日期：2018-03-07 00:00:00

abstract：:Enzymes play important roles in most of the biological processes. Although only a small fraction of residues are directly involved in catalytic reactions, these catalytic residues are the most crucial parts in enzymes. The study of the fundamental and unique features of catalytic residues benefits the understanding of...

journal_title：BioMed research international

authors： Chien YT,Huang SW

更新日期：2013-01-01 00:00:00

abstract：:Background and Purposes. The 320-detector row CT scanner enables visualization of whole-brain hemodynamic information (dynamic CT angiography (CTA) derived from CT perfusion scans). However, arterial image quality in dynamic CTA (dCTA) is inferior to arterial image quality in standard CTA. This study evaluates whether...

journal_title：BioMed research international

authors： Ghariq E,Mendrik AM,Willems PW,Joemai RM,Ghariq E,Vonken EJ,van Osch MJ,van Walderveen MA

更新日期：2014-01-01 00:00:00

abstract：:Emergence and spread of pandemic strains of Vibrio parahaemolyticus have drawn attention to make detailed study on their genomes. The pathogenicity of V. parahaemolyticus has been associated with thermostable-direct hemolysin (TDH) and/or TDH-related hemolysin (TRH). The present study evaluated characteristics of tdh ...

journal_title：BioMed research international

authors： Bhowmik SK,Pazhani GP,Ramamurthy T

更新日期：2014-01-01 00:00:00

abstract：:Oral mucosa is an attractive region for the local and systemic application of many drugs. Oral mucoadhesive films are preferred for their prolonged time of residence, the improved bioavailability of the drug they contain, their painless application, their protection against lesions, and their nonirritating properties....

journal_title：BioMed research international

authors： Landová H,Vetchý D,Gajdziok J,Doležel P,Muselík J,Dvořáčková K,Jekl V,Hauptman K,Knotek Z

更新日期：2014-01-01 00:00:00

abstract：:This study evaluated the potential relationship between exosomal miRNAs and clinical symptoms in patients with multiple myeloma (MM). Forty-eight newly diagnosed myeloma patients and sixteen normal donors were enrolled in the study. The results showed that the relative expression levels of let-7c-5p, let-7d-5p, miR-14...

journal_title：BioMed research international

authors： Zhang ZY,Li YC,Geng CY,Wang HJ,Chen WM

更新日期：2019-12-14 00:00:00

abstract：:Alpha-linolenic acid (ALA) is plant-based essential omega-3 polyunsaturated fatty acids that must be obtained through the diet. This could explain in part why the severe deficiency in omega-3 intake pointed by numerous epidemiologic studies may increase the brain's vulnerability representing an important risk factor i...

journal_title：BioMed research international

authors： Blondeau N,Lipsky RH,Bourourou M,Duncan MW,Gorelick PB,Marini AM

更新日期：2015-01-01 00:00:00

abstract：:The aim of the present study was to evaluate the antitumor potential of iminoflavones in in vitro and in vivo anticancer models. Preliminary screening in various cancer cell lines revealed four potential iminoflavones out of which IMF-8 was taken based on its activity against colon cancer cells. This was further confi...

journal_title：BioMed research international

authors： Prasad VG,Kawade S,Jayashree BS,Reddy ND,Francis A,Nayak PG,Kishore A,Nandakumar K,Rao CM,Shenoy RR

更新日期：2014-01-01 00:00:00

abstract：:The incidence and rates of diagnosis of drug-induced liver injury (DILI) have been increasing in recent years as findings from basic research and the examination of clinical databases reveal information about the clinical course, etiology, and prognosis of this complex disease. The prevalence of metabolic comorbiditie...

journal_title：BioMed research international

authors： Li X,Gao P,Niu J

更新日期：2019-08-18 00:00:00

abstract：Introduction:To investigate the clinical results of arthroscopic management for the unstable inferior leaf of the lateral meniscus anterior horn and associated cysts through an inframeniscal portal. Methods:From March 2005 to October 2014, 64 patients with an unstable inferior leaf of the lateral meniscus anterior hor...

journal_title：BioMed research international

authors： Chen D,Li Q,Sun Y,Qin J,Yao Y,Jiang Q

更新日期：2017-01-01 00:00:00

abstract：Objective:To observe the effect of adenosine A1 receptor in the hippocampus of mice on GSK-3β phosphorylation level and elucidate the underlying mechanisms of electroacupuncture pretreatment by activating Α1 receptor mediating cerebral ischemia-reperfusion injury. Method:The model of middle cerebral artery occlusion (...

journal_title：BioMed research international

authors： Geng W,Cai L,Han K,Li D,Mo Y,Dai Q,Tang H,Zhang M,Akuetteh PDP,Balelang MF,Wang J

更新日期：2020-02-20 00:00:00

abstract：:[This retracts the article DOI: 10.1155/2019/5879089.]. ...

journal_title：BioMed research international

authors： BioMed Research International .

更新日期：2020-08-26 00:00:00

abstract：:Different batches of atorvastatin, represented by two immediate release formulation designs, were studied using a novel dynamic dissolution apparatus, simulating stomach and small intestine. A universal dissolution method was employed which simulated the physiology of human gastrointestinal tract, including the precis...

journal_title：BioMed research international

authors： Čulen M,Tuszyński PK,Polak S,Jachowicz R,Mendyk A,Dohnal J

更新日期：2015-01-01 00:00:00

abstract：:Lycium barbarum is a famous plant in the traditional Chinese medicine. The plant is known to have health-promoting bioactive components. The properties of Lycium barbarum berries cultivated in Umbria (Italy) and their effect on human hepatocellular carcinoma cells (HepG2) have been investigated in this work. The obtai...

journal_title：BioMed research international

authors： Ceccarini MR,Vannini S,Cataldi S,Moretti M,Villarini M,Fioretti B,Albi E,Beccari T,Codini M

更新日期：2016-01-01 00:00:00

abstract：PURPOSE:Electrical Bioimpedance Cerebral Monitoring is assessment in real time of health of brain tissue through study of passive dielectric properties of brain. During the last two decades theory and technology have been developed in parallel with animal experiments aiming to confirm feasibility of using bioimpedance-...

journal_title：BioMed research international

authors： Seoane F,Reza Atefi S,Tomner J,Kostulas K,Lindecrantz K

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:Fever in systemic lupus erythematosus (SLE) can be caused by infection or flare-up of the disease. This study aimed to determine whether the ratio of the level of erythrocyte-bound C4d to that of complement receptor 1 (C4d/CR1) can serve as a useful biomarker in the differentiation between infection and flare...

journal_title：BioMed research international

authors： Chen CH,Tai SB,Chen HC,Yang DH,Peng MY,Lin YF

更新日期：2015-01-01 00:00:00

abstract：:Epidemiological studies have proven an association between consumption of polyphenols and prevention of Alzheimer's disease, the most common form of dementia characterized by extracellular deposition of amyloid beta plaques. The aim of this study is pharmacological screening of the aqueous alcohol extract of Markhamia...

journal_title：BioMed research international

authors： Hassaan Y,Handoussa H,El-Khatib AH,Linscheid MW,El Sayed N,Ayoub N

更新日期：2014-01-01 00:00:00

abstract：:Background. Surgical treatment of proximal humeral fractures (PHF) in osteoporotic bone of elderly patients is challenging. The aim of this retrospective study was to evaluate the clinical and radiological outcome after percutaneous reduction and internal fixation of osteoporotic PHF in geriatric patients using the se...

journal_title：BioMed research international

authors： Bogner R,Ortmaier R,Moroder P,Karpik S,Wutte C,Lederer S,Auffarth A,Resch H

更新日期：2016-01-01 00:00:00

abstract：:Technological processes in the dairy industry and the further passage through the gastrointestinal tract could impair viability and functionality of probiotic bifidobacteria. In the present work, the growth in milk of nine bifidobacterial strains shared by mother and child, their survival to freeze-drying and cold sto...

journal_title：BioMed research international

authors： Peirotén A,Gaya P,Arqués JL,Medina M,Rodríguez E

更新日期：2019-01-17 00:00:00

abstract：:Cancer related fatigue (CRF) is a common and debilitating symptom that can influence quality of life (QoL) in cancer patients. The increase in survival times stresses for a better understanding of how CRF affects patients' QoL. This was a cross-sectional descriptive study with 148 randomly recruited prostate cancer pa...

journal_title：BioMed research international

authors： Charalambous A,Kouta C

更新日期：2016-01-01 00:00:00

abstract：:Nematodes infections are responsible for debilitating conditions and economic losses in domestic animals as well as livestock and are considered an important public health problem due to the high prevalence in humans. The nematode resistance for drugs has been reported for livestock, highlighting the importance for de...

journal_title：BioMed research international

authors： Ferreira SR,Mendes TA,Bueno LL,de Araújo JV,Bartholomeu DC,Fujiwara RT

更新日期：2015-01-01 00:00:00

abstract：:We identified a nitidine- (NTD-) accumulating organelle and evaluated the net cytotoxicity of accumulated NTD. To evaluate tumor cell selectivity of the drug, we evaluated its selective cytotoxicity against 39 human cancer cell lines (JFCR39 panel), and the profile was compared with those of known anticancer drugs. Or...

journal_title：BioMed research international

authors： Iwasaki H,Inafuku M,Taira N,Saito S,Oku H

更新日期：2017-01-01 00:00:00