Abstract:
BACKGROUND:Transcranial direct current stimulation (tDCS) has been used to improve exercise performance, though the protocols used, and results found are mixed. OBJECTIVE:We aimed to analyze the effect of tDCS on improving exercise performance. METHODS:A systematic search was performed on the following databases, until December 2017: PubMed/MEDLINE, Embase, Web of Science, SCOPUS, and SportDiscus. Full-text articles that used tDCS for exercise performance improvement in adults were included. We compared the effect of anodal (anode near nominal target) and cathodal (cathode near nominal target) tDCS to a sham/control condition on the outcome measure (performance in isometric, isokinetic or dynamic strength exercise and whole-body exercise). RESULTS:22 studies (393 participants) were included in the qualitative synthesis and 11 studies (236 participants) in the meta-analysis. The primary motor cortex (M1) was the main nominal tDCS target (n = 16; 72.5%). A significant effect favoring anodal tDCS (a-tDCS) applied before exercise over M1 was found on cycling time to exhaustion (mean difference = 93.41 s; 95%CI = 27.39 s-159.43 s) but this result was strongly influenced by one study (weight = 84%), no effect was found for cathodal tDCS (c-tDCS). No significant effect was found for a-tDCS applied on M1 before or during exercise on isometric muscle strength of the upper or lower limbs. Studies regarding a-tDCS over M1 on isokinetic muscle strength presented mixed results. Individual results of studies using a-tDCS applied over the prefrontal and motor cortices either before or during dynamic muscle strength testing showed positive results, but performing meta-analysis was not possible. CONCLUSION:For the protocols tested, a-tDCS but not c-tDCS vs. sham over M1 improved exercise performance in cycling only. However, this result was driven by a single study, which when removed was no longer significant. Further well-controlled studies with larger sample sizes and broader exploration of the tDCS montages and doses are warranted.
journal_name
Brain Stimuljournal_title
Brain stimulationauthors
Machado DGDS,Unal G,Andrade SM,Moreira A,Altimari LR,Brunoni AR,Perrey S,Mauger AR,Bikson M,Okano AHdoi
10.1016/j.brs.2018.12.227subject
Has Abstractpub_date
2019-01-01 00:00:00pages
593-605issue
3eissn
1935-861Xissn
1876-4754pii
S1935-861X(18)30646-6journal_volume
12pub_type
杂志文章,meta分析abstract:BACKGROUND:Transcranial direct current stimulation (tDCS) was recently shown to promote recovery of voluntary signs of consciousness in some patients in minimally conscious state (MCS). However, it remains unclear why clinical improvement is only observed in a subgroup of patients. OBJECTIVES:In this retrospective stu...
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abstract:BACKGROUND:Although cervical vagus nerve stimulation is effective for reducing infarct volume in rats, it is not feasible for acute human stroke as it requires surgical incision of the neck. We hypothesized that stimulation of the dermatome in the external ear innervated by the vagus nerve (auricular vagus nerve stimul...
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pub_type: 杂志文章
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更新日期:2010-10-01 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章,随机对照试验
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pub_type: 杂志文章
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pub_type: 杂志文章,随机对照试验
doi:10.1016/j.brs.2016.05.009
更新日期:2016-09-01 00:00:00
abstract:BACKGROUND:The use of repetitive transcranial magnetic stimulation (rTMS) as both therapeutic and experimental tools has grown enormously over the past decade. However, variability in response to rTMS is one challenge that remains to be solved. Estrogen can impact neural plasticity and may also affect plastic changes f...
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abstract:BACKGROUND:Previous studies have shown that primary motor cortex (M1) excitability is modulated by motor skill learning and that the M1 plays a crucial role in motor memory. However, the following questions remain: (1) At what stage do changes in M1 excitability occur? (2) Are learning-induced changes in leg M1 excitab...
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pub_type: 杂志文章
doi:10.1016/j.brs.2015.07.025
更新日期:2015-11-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.brs.2013.11.004
更新日期:2014-03-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.brs.2015.11.008
更新日期:2016-03-01 00:00:00
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pub_type: 杂志文章,随机对照试验
doi:10.1016/j.brs.2012.10.005
更新日期:2013-07-01 00:00:00
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doi:10.1016/j.brs.2015.08.003
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pub_type: 杂志文章
doi:10.1016/j.brs.2014.04.004
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更新日期:2009-01-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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更新日期:2016-03-01 00:00:00
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更新日期:2017-01-01 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章
doi:10.1016/j.brs.2020.04.011
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abstract:BACKGROUND:Repetitive transcranial magnetic stimulation (rTMS) has shown promise as a treatment for refractory auditory hallucinations (AH) in Schizophrenia. Most previous studies have examined the effect of low frequency, left-sided stimulation (LFL) (1 Hz) to the temporoparietal cortex (TPC). Priming stimulation (6 H...
journal_title:Brain stimulation
pub_type: 杂志文章,随机对照试验
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