Bioinformatics Analysis of the Molecular Mechanism of Aging on Fracture Healing.

abstract：:Due to anthropogenic activities the relative concentrations of cadmium and manganese have increased in the marine environment. Cephalopods are able to accumulate such metals and, as inhabitant of coastal waters, Octopus vulgaris is continuously exposed to anthropogenic activities. Since no study is available on the ef...

journal_title：BioMed research international

authors： Nicosia A,Salamone M,Mazzola S,Cuttitta A

更新日期：2015-01-01 00:00:00

abstract：:Interactions between proteins and drugs, which can lead to formation of stable drug-protein complexes, have important implications on several processes related to human health. These interactions can affect, for instance, free concentration, biological activity, and metabolism of the drugs in the blood stream. Here, w...

journal_title：BioMed research international

authors： Gorza FD,Pedro GC,Trescher TF,da Silva RJ,Silva JR,de Souza NC

更新日期：2014-01-01 00:00:00

abstract：Background:Pakistan is a country with one of the highest burden of tuberculosis (TB) in the world, and therefore, it is imperative to revisit the design of behaviour change interventions in the program. This study was designed to understand and assess the knowledge, awareness, perceptions, and health-seeking behaviour ...

journal_title：BioMed research international

authors： Khan A,Shaikh BT,Baig MA

更新日期：2020-04-21 00:00:00

abstract：:Reactive oxygen species (ROS) damage macromolecules and cellular components in nearly all kinds of cells and often generate toxic intracellular byproducts. In this work, aldehyde generation derived from the Escherichia coli membrane oxidation as well as membrane fatty acid profiles, protein oxidation, and bacterial re...

journal_title：BioMed research international

authors： Pradenas GA,Díaz-Vásquez WA,Pérez-Donoso JM,Vásquez CC

更新日期：2013-01-01 00:00:00

abstract：:Progression of idiopathic dilated cardiomyopathy (IDCM) is marked with extensive left ventricular remodeling whose clinical manifestations and molecular basis are poorly understood. We aimed to evaluate the clinical potential of titin ligands in monitoring progression of cardiac remodeling associated with end-stage ID...

journal_title：BioMed research international

authors： Bogomolovas J,Brohm K,Čelutkienė J,Balčiūnaitė G,Bironaitė D,Bukelskienė V,Daunoravičus D,Witt CC,Fielitz J,Grabauskienė V,Labeit S

更新日期：2015-01-01 00:00:00

abstract：INTRODUCTION:Tuberculosis is still one of the most important health problems in developing countries and increasing drug resistance is the main concern for its treatment. This study was designed to characterize the drug resistant Mycobacterium tuberculosis isolated from patients suffering from pulmonary tuberculosis in...

journal_title：BioMed research international

authors： Tavanaee Sani A,Shakiba A,Salehi M,Bahrami Taghanaki HR,Ayati Fard SF,Ghazvini K

更新日期：2015-01-01 00:00:00

abstract：:Purpose. We examined the role of miR-20b in development of thymoma-associated myasthenia gravis, especially in T cell proliferation and activation. Materials and Methods. Using qRT-PCR, we assessed expression levels of miR-20b and its target genes in cultured cells and patient samples and examined the proliferation of...

journal_title：BioMed research international

authors： Xin Y,Cai H,Lu T,Zhang Y,Yang Y,Cui Y

更新日期：2016-01-01 00:00:00

abstract：Background:Osteoarthritis (OA) is a common disease characterized by articular cartilage degeneration and secondary hyperosteogenesis. Genetic factors are associated with the occurrence of OA. While several studies have shown that the matrix metalloproteinase-1- (MMP-1-) 1607 1G/2G (rs1799750) polymorphism may be relate...

journal_title：BioMed research international

authors： Liu J,Wang G,Peng Z

更新日期：2020-05-20 00:00:00

abstract：:The anaerobic skin commensal Propionibacterium acnes is an underestimated cause of human infections and clinical conditions. Previous studies have suggested a role for the bacterium in lumbar disc herniation and infection. To further investigate this, five biopsy samples were surgically excised from each of 64 patient...

journal_title：BioMed research international

authors： Rollason J,McDowell A,Albert HB,Barnard E,Worthington T,Hilton AC,Vernallis A,Patrick S,Elliott T,Lambert P

更新日期：2013-01-01 00:00:00

abstract：:The exosomes are derived from mesenchymal stem cells (MSCs) and may be potentially used as an alternative for cell therapy, for treating diabetic wounds, and aid in angiogenesis. This study, aimed to investigate whether exosomes originated from bone marrow-derived MSCs (BMSCs) preconditioned by deferoxamine (DFO-Exos)...

journal_title：BioMed research international

authors： Ding J,Wang X,Chen B,Zhang J,Xu J

更新日期：2019-05-05 00:00:00

abstract：:To establish a reliable isoproterenol induced heart dysfunction fetal rat model and understand the switches of contractile proteins, 45 pregnant rats were divided into 15 mg/kg-once, 15 mg/kg-twice, sham-operated once, sham-operated twice, and control groups. And 18 adult rats were divided into isoproterenol-treated a...

journal_title：BioMed research international

authors： Li Y,Fang J,Hua Y,Wang C,Mu D,Zhou K

更新日期：2014-01-01 00:00:00

abstract：:Mexico has one of the highest incidences of childhood leukemia worldwide and significantly higher mortality rates for this disease compared with other countries. One possible cause is the high prevalence of gene rearrangements associated with the etiology or with a poor prognosis of childhood acute lymphoblastic leuke...

journal_title：BioMed research international

authors： Bekker-Méndez VC,Miranda-Peralta E,Núñez-Enríquez JC,Olarte-Carrillo I,Guerra-Castillo FX,Pompa-Mera EN,Ocaña-Mondragón A,Rangel-López A,Bernáldez-Ríos R,Medina-Sanson A,Jiménez-Hernández E,Amador-Sánchez R,Peñaloza-González JG,

更新日期：2014-01-01 00:00:00

abstract：Background:The aim of our study was to investigate the impact of abdominal wall reconstruction surgery on tissue anatomy and to explore how flap surgery influences the patient's immune status. Methods:Experimental abdominal wall defects were created in 8 Sus scrofa (swine) animal models. The animals were divided into ...

journal_title：BioMed research international

authors： Popa F,Georgescu AV

更新日期：2017-01-01 00:00:00

abstract：:Long-term chronic intermittent exposure to altitude hypoxia is a labor phenomenon requiring further research. Using a rat model, we examined whether this type of exposure differed from chronic exposure in terms of pulmonary artery remodeling and other features. Rats were subjected to chronic hypoxia (CH, n = 9) and lo...

journal_title：BioMed research international

authors： Brito J,Siques P,Arribas SM,López de Pablo AL,González MC,Naveas N,Arriaza K,Flores K,León-Velarde F,Pulido R,Ordenes S,López MR

更新日期：2015-01-01 00:00:00

abstract：:Gravity is crucial for spatial perception, postural equilibrium, and movement generation. The vestibular apparatus is the main sensory system involved in monitoring gravity. Hair cells in the vestibular maculae respond to gravitoinertial forces, but they cannot distinguish between linear accelerations and changes of h...

journal_title：BioMed research international

authors： Lacquaniti F,Bosco G,Gravano S,Indovina I,La Scaleia B,Maffei V,Zago M

更新日期：2014-01-01 00:00:00

abstract：:The spectrum of kidney disease-associated monoclonal immunoglobulin and plasma cell malignancies is remarkably broad and encompasses nearly all nephropathologic entities. Multiple myeloma with kidney impairment at presentation is a medical emergency since the recovery of kidney function is associated with survival ben...

journal_title：BioMed research international

authors： Mussap M,Merlini G

更新日期：2014-01-01 00:00:00

abstract：:Some degree of external root resorption is a frequent, unpredictable, and unavoidable consequence of orthodontic tooth movement mediated by odontoclasts/cementoclasts originating from circulating precursor cells in the periodontal ligament. Its pathogenesis involves mechanical forces initiating complex interactions be...

journal_title：BioMed research international

authors： Feller L,Khammissa RA,Thomadakis G,Fourie J,Lemmer J

更新日期：2016-01-01 00:00:00

abstract：:Pancreatic ductal adenocarcinoma (PDA) is the fourth most common cancer causing death in the United States. Early tumor recurrence is an important contributor to the dismal prognosis. The availability of an accurate prognostic biomarker for predicting disease recurrence following curative resection will be beneficial ...

journal_title：BioMed research international

authors： Osayi SN,Bloomston M,Schmidt CM,Ellison EC,Muscarella P

更新日期：2014-01-01 00:00:00

abstract：:Human mesenchymal stem cells (MSCs) have an intrinsic property for homing towards tumor sites and can be used as tumor-tropic vectors for tumor therapy. But very limited studies investigated the antitumor properties of MSCs themselves. In this study we investigated the antiglioma properties of two easily accessible MS...

journal_title：BioMed research international

authors： Yang C,Lei D,Ouyang W,Ren J,Li H,Hu J,Huang S

更新日期：2014-01-01 00:00:00

abstract：:The present study deals with the enzymatic synthesis of biodiesel by transesterification of Jatropha oil (Jatropha curcas L.) with ethanol in a solvent-free system. Seven commercial lipase preparations immobilized by covalent attachment on epoxy-polysiloxane-polyvinyl alcohol composite (epoxy-SiO2-PVA) were tested as ...

journal_title：BioMed research international

authors： Souza LT,Mendes AA,de Castro HF

更新日期：2016-01-01 00:00:00

abstract：Purpose:To analyze retrospectively the clinical efficacy and safety for patients treated with fractionated stereotactic radiation therapy (FSRT) using volumetric modulated arc therapy. Methods:Between 2016 and 2017, 46 patients with solitary brain metastasis who underwent FSRT consisting of 25-40 Gy/5 fractions were r...

journal_title：BioMed research international

authors： Zhou C,Xia Y,Huang P,Guan L,Shen X,Hao D,Chen M,Ren H,Lian L,Yin H

更新日期：2020-09-09 00:00:00

abstract：:The neural dysfunction is triggered by cellular and molecular events that provoke neurotoxicity and neural death. Currently, neurodegenerative diseases are increasingly common, and available treatments are focused on relieving symptoms. Based on the above, in this review we describe the participation of vitexin in the...

journal_title：BioMed research international

authors： Lima LKF,Pereira SKS,Junior RDSS,Santos FPDS,Nascimento AS,Feitosa CM,Figuerêdo JS,Cavalcante ADN,Araújo ECDC,Rai M

更新日期：2018-12-05 00:00:00

abstract：:Heart failure (HF) is associated with mitochondrial dysfunction and energy metabolism impairment. MicroRNAs are implicated in the development of heart failure. However, the mitochondria enriched microRNA during heart failure remains elusive. Here, we generated a pressure overload-induced early and late stage heart fai...

journal_title：BioMed research international

authors： Wang X,Song C,Zhou X,Han X,Li J,Wang Z,Shang H,Liu Y,Cao H

更新日期：2017-01-01 00:00:00

abstract：:The aim of this study was to evaluate whether blood transfusions affect overall survival (OS) and progression-free survival (PFS) in newly diagnosed multiple myeloma (MM) patients without hematopoietic stem cell transplantation. A total of 181 patients were enrolled and divided into two groups: 68 patients in the tran...

journal_title：BioMed research international

authors： Fan L,Fu D,Zhang J,Huang H,Wang Q,Ye Y,Xie Q

更新日期：2017-01-01 00:00:00

abstract：:IL-1 family includes IL-38 (IL-1F10) and the subfamily of IL-36 and is the central mediators of inflammatory diseases, including pustular psoriasis, atopic dermatitis, rheumatoid arthritis, and gut inflammation. The purpose of the study was to evaluate on tissue of the patients with inflammatory bowel disease (IBD), t...

journal_title：BioMed research international

authors： Fonseca-Camarillo G,Furuzawa-Carballeda J,Iturriaga-Goyon E,Yamamoto-Furusho JK

更新日期：2018-12-10 00:00:00

abstract：:The aim of the present study was to analyze the relationship between the sum of the four limbs' pulse pressure (Sum-PP) and brachial-ankle pulse wave velocity (baPWV) and atherosclerosis risk factors and evaluate the feasibility of Sum-PP in diagnosing atherosclerosis systemically. For the purpose, a cross-sectional s...

journal_title：BioMed research international

authors： Zheng Y,Li Z,Shu H,Liu M,Chen Z,Huang J

更新日期：2015-01-01 00:00:00

abstract：:The aim of this study was to examine whether dexmedetomidine improves acute liver injury in a rat model. Twenty-eight male Wistar albino rats weighing 300-350 g were allocated randomly to four groups. In group 1, normal saline (NS) was injected into the lungs and rats were allowed to breathe spontaneously. In group 2,...

journal_title：BioMed research international

authors： Sen V,Güzel A,Şen HS,Ece A,Uluca U,Söker S,Doğan E,Kaplan İ,Deveci E

更新日期：2014-01-01 00:00:00

abstract：:The role of non-steroidal anti-inflammatory drugs in inflammatory bowel disease is controversial, as they have been implicated in disease aggravation. Different from other cyclooxygenase inhibitors, acetylsalicylic acid (ASA) enhances the formation of anti-inflammatory and proresolution lipoxins derived from arachidon...

journal_title：BioMed research international

authors： Köhnke T,Gomolka B,Bilal S,Zhou X,Sun Y,Rothe M,Baumgart DC,Weylandt KH

更新日期：2013-01-01 00:00:00

abstract：:The Purkinje network is a specialized conduction system within the heart that ensures the proper activation of the ventricles to produce effective contraction. Its role during ventricular arrhythmias is less clear, but some experimental studies have suggested that the Purkinje network may significantly affect the gene...

journal_title：BioMed research international

authors： Liu BR,Cherry EM

更新日期：2015-01-01 00:00:00

abstract：Purpose:High tibial osteotomy (HTO) has been adopted as an effective surgery for medial degeneration of the osteoarthritis (OA) knee. However, satisfactory outcomes necessitate the precise creation and distraction of osteotomized wedges and the use of intraoperative X-ray images to continually monitor the wedge-related...

journal_title：BioMed research international

authors： Yang JC,Chen CF,Luo CA,Chang MC,Lee OK,Huang Y,Lin SC

更新日期：2018-05-08 00:00:00