Abstract:
BACKGROUND:A remarkable relationship between upper airway conditions and lung diseases has been reported. At the same time, sinonasal findings in chronic cough patients have not been fully examined. OBJECTIVE:The purpose of this study is to show paranasal sinus findings and lung function in chronic cough patients without asthma and chest X-ray abnormalities. METHODS:A total of 1412 patients with persistent cough were enrolled in this study. Of these patients, 376 patients were evaluated for further examination, as the patients with asthma and/or chest X-ray abnormality were excluded from the study. Normal control subjects without any chronic respiratory symptoms were also recruited. Pulmonary function was examined by spirometry. A bronchial obstruction reversibility test was applied. The Lund-Mackay computed tomography (CT) score, peripheral blood eosinophil count, and immunoglobulin E concentration in serum samples were examined. The Sino-Nasal Outcome Test was used to determine the severity of clinical symptoms. RESULTS:The patients with an abnormal soft tissue shadow in the paranasal sinus had significant obstructive lung function. The percent predicted forced expiratory volume in 1 second (FEV1.0) and the FEV1.0/forced vital capacity ratio negatively correlated with Lund-Mackay CT scores both before and after bronchodilator inhalation. There was a statistically significant correlation between pulmonary function and eosinophil count. CONCLUSION:The patients with chronic cough frequently had paranasal sinus abnormalities. The Lund-Mackay CT score may be useful for assessing the condition of the lower airway in chronic cough patients. Upper airway examinations should play a part in the management of chronic cough.
journal_name
Am J Rhinol Allergyjournal_title
American journal of rhinology & allergyauthors
Kariya S,Okano M,Higaki T,Tachibana T,Rikimaru T,Nishizaki Kdoi
10.1177/1945892418825094subject
Has Abstractpub_date
2019-05-01 00:00:00pages
294-301issue
3eissn
1945-8924issn
1945-8932journal_volume
33pub_type
杂志文章abstract:BACKGROUND:Although nasal peak flow measurements have been proposed as a simple alternative method to assess nasal patency, which of nasal peak expiratory flow or nasal peak inspiratory flow (NPEF/NPIF) or the peak expiratory flow index or peak inspiratory flow index (PEFI/PIFI; the ratios between nasal and oral PEF or...
journal_title:American journal of rhinology & allergy
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abstract:BACKGROUND:This study reports the combined experience of the University of Miami and University of Pittsburgh with endoscopic endonasal resection of esthesioneuroblastoma (ENB). A retrospective case series review was performed in a tertiary care university hospital. METHODS:Twenty-three patients, 16 men and 7 women, w...
journal_title:American journal of rhinology & allergy
pub_type: 杂志文章,多中心研究
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journal_title:American journal of rhinology & allergy
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journal_title:American journal of rhinology & allergy
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journal_title:American journal of rhinology & allergy
pub_type: 临床试验,杂志文章
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journal_title:American journal of rhinology & allergy
pub_type: 杂志文章
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journal_title:American journal of rhinology & allergy
pub_type: 杂志文章
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journal_title:American journal of rhinology & allergy
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更新日期:2014-01-01 00:00:00
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journal_title:American journal of rhinology & allergy
pub_type: 杂志文章
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journal_title:American journal of rhinology & allergy
pub_type: 杂志文章
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更新日期:2009-07-01 00:00:00
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journal_title:American journal of rhinology & allergy
pub_type: 杂志文章,meta分析
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journal_title:American journal of rhinology & allergy
pub_type: 杂志文章
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更新日期:2010-09-01 00:00:00
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更新日期:2016-11-01 00:00:00
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journal_title:American journal of rhinology & allergy
pub_type: 杂志文章
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journal_title:American journal of rhinology & allergy
pub_type: 杂志文章
doi:10.1177/1945892418762845
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journal_title:American journal of rhinology & allergy
pub_type: 杂志文章
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journal_title:American journal of rhinology & allergy
pub_type: 杂志文章
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