Abstract:
:Sarcoidosis is a multisystem granulomatous disorder of unknown etiology. The annual incidence of systemic sarcoidosis is estimated at 10-20 per 100,000 individuals. Owing to the recent advances in imaging modalities, cardiac sarcoidosis (CS) is diagnosed more frequently. The triad of CS includes conduction abnormality, ventricular tachycardia, and heart failure. Atrial and ventricular arrhythmias are caused by either inflammation or scar formation. Inflammation should be treated with immunosuppression and antiarrhythmic agents and scar formation should be treated with antiarrhythmics and/or ablation, in addition to implantable cardioverter defibrillator (ICD) implantation, if necessary. Ablation can provide a good outcome, but it might require bipolar ablation if the critical portion is located mid-myocardium. Late recurrence might be caused by reactivation of sarcoidosis, which would need to be evaluated by positron emission tomography-computed tomography imaging. Risk of sudden cardiac death (SCD) in patients with advanced atrioventricular block is not low, and ICD implantation could be considered instead of a pacemaker. For risk stratification for SCD, late gadolinium enhancement by cardiac magnetic resonance imaging or program stimulation is often used.
journal_name
Korean Circ Jjournal_title
Korean circulation journalauthors
Yada H,Soejima Kdoi
10.4070/kcj.2018.0432subject
Has Abstractpub_date
2019-02-01 00:00:00pages
119-133issue
2eissn
1738-5520issn
1738-5555pii
49.119journal_volume
49pub_type
杂志文章,评审abstract:BACKGROUND AND OBJECTIVES:Since statins and angiotensin receptor blockers are a frequently prescribed combination in patients with atherosclerotic cardiovascular diseases, we tested the interactive effects of simvastatin and losartan on atherosclerosis in apolipoprotein E (apoE)(-/-) mice. MATERIALS AND METHODS:Apolip...
journal_title:Korean circulation journal
pub_type: 杂志文章
doi:10.4070/kcj.2012.42.8.543
更新日期:2012-08-01 00:00:00
abstract::There have been great advances in ventricular assist device (VAD) treatment for pediatric patients with advanced heart failure. VAD support provides more time for the patient in the heart transplant waiting list. Augmented cardiac output improves heart failure symptoms, end-organ function, and general condition, and c...
journal_title:Korean circulation journal
pub_type: 杂志文章,评审
doi:10.4070/kcj.2019.0163
更新日期:2019-08-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Coronary artery disease (CAD) is a major cause of heart failure associated with left ventricular systolic dysfunction (LVSD). The prognosis of LVSD is significantly influenced by the etiology of heart failure and therefore, differentiation of significant CAD from other etiologies is important....
journal_title:Korean circulation journal
pub_type: 杂志文章
doi:10.4070/kcj.2010.40.12.665
更新日期:2010-12-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Statin therapy after percutaneous coronary intervention (PCI) has been associated with reduced major adverse cardiovascular events (MACE). However, it has been less clear as to whether statin therapy before acute coronary syndrome (ACS) is beneficial. We studied the effect of previous statin t...
journal_title:Korean circulation journal
pub_type: 杂志文章
doi:10.4070/kcj.2011.41.8.458
更新日期:2011-08-01 00:00:00
abstract::Long QT syndrome (LQTS) is a rare cardiac channelopathy associated with syncope and sudden death due to torsades de pointes and ventricular fibrillation. Syncope and sudden death are frequently associated with physical and emotional stress. Management of patients with LQTS consists of life-style modification, β-blocke...
journal_title:Korean circulation journal
pub_type: 杂志文章,评审
doi:10.4070/kcj.2016.46.6.747
更新日期:2016-11-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The prevalence of arthritis, which is often treated with celecoxib, is high in patients with coronary artery disease. Furthermore, celecoxib has been reported to reduce restenosis after coronary stenting by inhibiting expression of the proto-oncogene Akt. A concern is that celecoxib increases ...
journal_title:Korean circulation journal
pub_type: 杂志文章
doi:10.4070/kcj.2010.40.7.321
更新日期:2010-07-01 00:00:00
abstract::For over 3 decades, it has been known that reentry circuits for ventricular tachycardia (VT) are not limited to the subendocardial myocardium. Rather, intramural or subepicardial substrates may also give rise to VT, particularly in those with non-ischemic cardiomyopathy. Percutaneous epicardial mapping and ablation ha...
journal_title:Korean circulation journal
pub_type: 杂志文章,评审
doi:10.4070/kcj.2018.0210
更新日期:2018-09-01 00:00:00
abstract::Left atrial intramural hematoma is a very rare complication of radiofrequency ablation procedures. A patient with tachyarrhythmia underwent radiofrequency catheter ablation. Echocardiography performed the following morning showed a large mass in the left atrium, suggestive of intramural hematoma formation. The patient...
journal_title:Korean circulation journal
pub_type: 杂志文章
doi:10.4070/kcj.2016.46.4.580
更新日期:2016-07-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The prognosis and natural history of bradycardia related to drugs such as beta-blockers and non-dihydropyridine calcium channel blockers are not well known. SUBJECTS AND METHODS:We retrospectively analyzed 38 consecutive patients (age 69+/-11, 21 women) with drug-related bradycardia (DRB) bet...
journal_title:Korean circulation journal
pub_type: 杂志文章
doi:10.4070/kcj.2009.39.9.367
更新日期:2009-09-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Atherosclerosis is characterized by a hypercoagulable state, during which coagulation and fibrinolytic factors are activated simultaneously. However, details regarding the thrombolytic pathway in this context remain unknown. Here we investigated how direct long-term inhibition of thrombin infl...
journal_title:Korean circulation journal
pub_type: 杂志文章
doi:10.4070/kcj.2020.0055
更新日期:2020-09-01 00:00:00
abstract::The Prospective comparison of Angiotensin Receptor-neprilysin inhibitor (ARNI) with Angiotensin converting enzyme inhibitor (ACEI) to Determine Impact on Global Mortality and morbidity in Heart Failure (HF) trial (PARADIGM-HF) showed that adding a neprilysin inhibitor (sacubitril) to a renin-angiotensin system blocker...
journal_title:Korean circulation journal
pub_type: 杂志文章,评审
doi:10.4070/kcj.2019.0136
更新日期:2019-06-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Clinical data for Korean patients with bicuspid aortic valve (BAV) that underwent aortic valve (AV) surgery are currently limited. METHODS:Data for 1,160 consecutive adult BAV patients who underwent AV surgery from 2000 to 2014 in 4 tertiary referral centers were retrospectively analyzed. A s...
journal_title:Korean circulation journal
pub_type: 杂志文章
doi:10.4070/kcj.2017.0124
更新日期:2018-01-01 00:00:00
abstract::Treatments of choice for cardiac implantable electronic device (CIED) infections are the removal of the entire CIED system, control of infection, and new device implantation. Occasionally, a complete CIED removal can not be performed for several reasons, such as very old age, severe comobidity, limited life expectancy...
journal_title:Korean circulation journal
pub_type: 杂志文章
doi:10.4070/kcj.2011.41.1.46
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Recently, Genoss drug-eluting stent (DES)™ stent comprising cobalt-chromium platform with an ultrathin strut thickness, sirolimus, and an abluminal biodegradable polymer was developed. Owing to the lack of substantial evidence for the safety and efficacy of this stent, we report 12-month resul...
journal_title:Korean circulation journal
pub_type: 杂志文章
doi:10.4070/kcj.2019.0258
更新日期:2020-04-01 00:00:00
abstract::A 35-year-old Korean man with a 10-year history of ulcerative colitis (UC) presented with pain and swelling of the right neck. The patient was diagnosed with Takayasu's arteritis (TA) and had human leukocyte antigen (HLA) B-52, which is frequently found in patients having both UC and Takayasu's disease concurrently on...
journal_title:Korean circulation journal
pub_type: 杂志文章
doi:10.4070/kcj.2013.43.2.135
更新日期:2013-02-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Angiotensin-II receptor blockers (ARBs) are known to reduce the development of atrial fibrillation (AF) through reverse-remodeling. However, the effect of ARBs on thrombogenicity in AF remains unknown. MATERIALS AND METHODS:Twelve dogs were assigned to control (n=4), ARB (candesartan cilexiti...
journal_title:Korean circulation journal
pub_type: 杂志文章
doi:10.4070/kcj.2016.46.3.335
更新日期:2016-05-01 00:00:00
abstract::Coronary artery anomalies are rare presentations in primary percutaneous coronary interventions of acute myocardial infarction. Herein, we report the case of a 59-year-old man with acute anterior myocardial infarction who had anomalous separate origin of left anterior descending artery (LAD) and left circumflex artery...
journal_title:Korean circulation journal
pub_type: 杂志文章
doi:10.4070/kcj.2013.43.6.408
更新日期:2013-06-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Hypercholesterolemia is a key factor in the development of atherosclerosis. We sought to evaluate the relation between hypercholesterolemia and plaque composition in patients with coronary artery disease. SUBJECTS AND METHODS:Study subjects consisted of 323 patients (mean 61.5 years, 226 male...
journal_title:Korean circulation journal
pub_type: 杂志文章
doi:10.4070/kcj.2013.43.1.23
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Pentraxin 3 (PTX3) was shown to be elevated in the acute phase of acute myocardial infarction (AMI) and to have prognostic significance in AMI patients. The aim of this study was to estimate whether the value of PTX3 could be used as a prognostic biomarker, with the global registry of acute co...
journal_title:Korean circulation journal
pub_type: 杂志文章
doi:10.4070/kcj.2010.40.8.370
更新日期:2010-08-01 00:00:00
abstract::The incidence of peri-stent graft infection (PGI) following thoracic endovascular aortic repair (TEVAR) is low, but the associated mortality rates are extremely high. The diagnosis of this complication can be difficult due to nonspecific symptoms. Here, we report a case of PGI combined with an aorto-esophageal fistula...
journal_title:Korean circulation journal
pub_type: 杂志文章
doi:10.4070/kcj.2012.42.5.366
更新日期:2012-05-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Experimental protocols for remote ischemic conditioning (RIC) utilize models in which a tourniquet is placed around the hindlimb or effluent is collected from an isolated heart. In analyzing the humoral factors that act as signal transducers in these models, sampled blood can be influenced by ...
journal_title:Korean circulation journal
pub_type: 杂志文章
doi:10.4070/kcj.2017.0092
更新日期:2017-09-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Undiagnosed diabetes mellitus (DM) or impaired glucose tolerance (IGT) is not uncommon in patients with coronary atherosclerosis and is known to be associated with abnormal scores for atherosclerosis surrogates. We sought to determine the prevalence of undiagnosed DM or IGT, and the associatio...
journal_title:Korean circulation journal
pub_type: 杂志文章
doi:10.4070/kcj.2010.40.2.62
更新日期:2010-02-01 00:00:00
abstract::Swine-origin influenza A (H1N1) is caused by a new strain of the influenza virus. The disease has spread rapidly and was declared a pandemic in April, 2009. So far, however, there is a scarcity of information regarding the complications of swine influenza. A report of the disease in the winter of 2009 in the Southern ...
journal_title:Korean circulation journal
pub_type: 杂志文章
doi:10.4070/kcj.2010.40.10.539
更新日期:2010-10-01 00:00:00
abstract::Hepatocellular carcinoma (HCC) with metastasis to the heart is uncommon. We report a rare case of left atrial metastasis of HCC which was resected palliatively as a live-saving procedure with the use of cardiopulmonary bypass. Despite chemoembolization, which was undertaken 11 times, cardiac metastasis occurred. Moreo...
journal_title:Korean circulation journal
pub_type: 杂志文章
doi:10.4070/kcj.2011.41.9.542
更新日期:2011-09-01 00:00:00
abstract::Congestive heart failure (HF) is a morbidity that is increasing worldwide due to the aging population and improvement in (acute) care for patients with cardiovascular diseases. The prognosis for patients with HF is very poor without treatment. Furthermore, (repeated) hospitalizations for cardiac decompensation cause a...
journal_title:Korean circulation journal
pub_type: 杂志文章,评审
doi:10.4070/kcj.2017.0030
更新日期:2017-09-01 00:00:00
abstract::Unguarded tricuspid regurgitation (TR) due to a flail tricuspid leaflet is a rare condition of newborn cyanosis. A high perinatal mortality has been associated with this fatal condition. But, there are feasible surgical repairs to improve survival. We report the case of a male full-term neonate with intractable hypoxi...
journal_title:Korean circulation journal
pub_type: 杂志文章
doi:10.4070/kcj.2015.45.4.340
更新日期:2015-07-01 00:00:00
abstract::Acute pulmonary embolism (APE) is characterized by numerous clinical manifestations which are the result of a complex interplay between different organs; the symptoms are therefore various and part of a complex clinical picture. For this reason, it may not be easy to make an immediate diagnosis. This is a comprehensiv...
journal_title:Korean circulation journal
pub_type: 杂志文章,评审
doi:10.4070/kcj.2017.0314
更新日期:2018-05-01 00:00:00
abstract::Drug-eluting stents (DES) are considered the treatment of choice for most patients with obstructive coronary artery disease when percutaneous intervention (PCI) is feasible. However, stent thrombosis seems to occur more frequently with DES and occasionally is associated with resistance to anti-platelet drugs. We have ...
journal_title:Korean circulation journal
pub_type: 杂志文章
doi:10.4070/kcj.2009.39.10.434
更新日期:2009-10-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Increased vascular wall shear stress by elevated plasma viscosity significantly enhances the endothelial nitric oxide synthase (eNOS) activity during an acute isovolemic hemodilution. Also the modulation of plasma viscosity has effects on the cardiac function that were revealed if a left ventr...
journal_title:Korean circulation journal
pub_type: 杂志文章
doi:10.4070/kcj.2014.44.2.105
更新日期:2014-03-01 00:00:00
abstract::A 34-year-old man, who had been treated with an endoscopic injection of a mixture of n-butyl-2-cyanoacrylate (Histoacryl) and Lipiodol for control of variceal bleeding 6 months previously, presented with an intracardiac mass in the right atrium (RA). Two-dimensional echocardiography revealed an intracardiac mass in th...
journal_title:Korean circulation journal
pub_type: 杂志文章
doi:10.4070/kcj.2010.40.9.468
更新日期:2010-09-01 00:00:00