Glycerolipid Composition of the Red Macroalga Agarophyton Chilensis and Comparison to the Closely Related Agarophyton Vermiculophyllum Producing Different Types of Eicosanoids.

abstract：:The present study investigated the effect of dietary astaxanthin (AX) on the growth performance, antioxidant parameters, and repair of hepatopancreas damage in Pacific white shrimp (Litopenaeus vannamei). To evaluate the hepatopancreas protective function of AX in shrimps, we compared the effect of five isonitrogenous...

journal_title：Marine drugs

authors： Yu Y,Liu Y,Yin P,Zhou W,Tian L,Liu Y,Xu D,Niu J

更新日期：2020-04-17 00:00:00

abstract：:The dinoflagellate Prorocentrum belizeanum is responsible for the production of several toxins involved in the red tide phenomenon known as Diarrhetic Shellfish Poisoning (DSP). In this paper we report on the biosynthetic origin of an okadaic acid water-soluble ester derivative, DTX5c, on the basis of the spectroscopi...

journal_title：Marine drugs

authors： Vilches TS,Norte M,Daranas AH,Fernández JJ

更新日期：2012-10-01 00:00:00

abstract：:Lipid A is a fundamental Gram-negative outer membrane component and the essential element of lipopolysaccharide (endotoxin), a potent immunostimulatory molecule. This work describes the metabolic adaptation of the lipid A acyl structure by Psychrobacter cryohalolentis at various temperatures in its facultative psychro...

journal_title：Marine drugs

authors： Sweet CR,Watson RE,Landis CA,Smith JP

更新日期：2015-07-30 00:00:00

abstract：:Seagrasses are high plants sharing adaptive metabolic features with both terrestrial plants and marine algae, resulting in a phytocomplex possibly endowed with interesting biological properties. The aim of this study is to evaluate the in vitro activities on skin cells of an ethanolic extract obtained from the leaves ...

journal_title：Marine drugs

authors： Cornara L,Pastorino G,Borghesi B,Salis A,Clericuzio M,Marchetti C,Damonte G,Burlando B

更新日期：2018-01-10 00:00:00

abstract：:Two new guaiazulene-based analogues, ochracenoids A (1) and B (2), along with four known analogues (3-6), were isolated from the gorgonian Anthogorgia ochracea collected from the South China Sea. The planar structures of the new compounds were elucidated by comprehensive spectroscopic data. The absolute configuration ...

journal_title：Marine drugs

authors： Zheng JJ,Shao CL,Chen M,Gan LS,Fang YC,Wang XH,Wang CY

更新日期：2014-03-14 00:00:00

abstract：:One new α-pyrone (nocapyrone R (1)), and three known γ-pyrones (nocapyrones B, H and L (2-4)) were isolated from the culture extract of a Nocardiopsis strain collected from marine sediment. Structures of these compounds were determined on the basis of spectroscopic data including NMR and MS. γ-Pyrones 2-4 were found t...

journal_title：Marine drugs

authors： Kim Y,Ogura H,Akasaka K,Oikawa T,Matsuura N,Imada C,Yasuda H,Igarashi Y

更新日期：2014-07-08 00:00:00

abstract：:The tropical marine cyanobacterium Moorena bouillonii occupies a large geographic range across the Indian and Western Tropical Pacific Oceans and is a prolific producer of structurally unique and biologically active natural products. An ensemble of computational approaches, including the creation of the ORCA (Objectiv...

journal_title：Marine drugs

authors： Leber CA,Naman CB,Keller L,Almaliti J,Caro-Diaz EJE,Glukhov E,Joseph V,Sajeevan TP,Reyes AJ,Biggs JS,Li T,Yuan Y,He S,Yan X,Gerwick WH

更新日期：2020-10-14 00:00:00

abstract：:Accurate characterization of biomass constituents is a crucial aspect of research in the biotechnological application of natural products. Here we report an efficient, fast and reproducible method for the identification and quantitation of fatty acids and complex lipids (triacylglycerols, glycolipids, phospholipids) i...

journal_title：Marine drugs

authors： Nuzzo G,Gallo C,d'Ippolito G,Cutignano A,Sardo A,Fontana A

更新日期：2013-09-30 00:00:00

abstract：:Biologically active compounds with different modes of action, such as, antiproliferative, antioxidant, antimicrotubule, have been isolated from marine sources, specifically algae and cyanobacteria. Recently research has been focused on peptides from marine animal sources, since they have been found as secondary metabo...

journal_title：Marine drugs

authors： Suarez-Jimenez GM,Burgos-Hernandez A,Ezquerra-Brauer JM

更新日期：2012-05-01 00:00:00

abstract：:Many marine bacteria produce exopolysaccharides (EPS) as a strategy for growth, adhering to solid surfaces, and to survive adverse conditions. There is growing interest in isolating new EPS producing bacteria from marine environments, particularly from extreme marine environments such as deep-sea hydrothermal vents ch...

journal_title：Marine drugs

authors： Poli A,Anzelmo G,Nicolaus B

更新日期：2010-06-03 00:00:00

abstract：:Mammalian target of rapamycin (mTOR) is a PI3K-related serine/threonine protein kinase that functions as a master regulator of cellular growth and metabolism, in response to nutrient and hormonal stimuli. mTOR functions in two distinct complexes-mTORC1 is sensitive to rapamycin, while, mTORC2 is insensitive to this dr...

journal_title：Marine drugs

authors： Ruiz-Torres V,Losada-Echeberría M,Herranz-López M,Barrajón-Catalán E,Galiano V,Micol V,Encinar JA

更新日期：2018-10-15 00:00:00

abstract：:A new compound containing a triene, a tetrahydropyran ring and glycine ester functionalities, restricticin B (1), together with four known compounds (2-5) were obtained from the EtOAc extract of the marine-derived fungus Penicillium janthinellum. The planar structure of 1 was determined by detailed analyses of MS, 1D ...

journal_title：Marine drugs

authors： Choi BK,Jo SH,Choi DK,Trinh PTH,Lee HS,Cao VA,Van TTT,Shin HJ

更新日期：2020-09-14 00:00:00

abstract：:Astaxanthin (ASX) is a carotenoid pigment with strong antioxidant properties. We have reported previously that ASX protects neurons from the noxious effects of amyloid-β peptide oligomers, which promote excessive mitochondrial reactive oxygen species (mROS) production and induce a sustained increase in cytoplasmic Ca2...

journal_title：Marine drugs

authors： García F,Lobos P,Ponce A,Cataldo K,Meza D,Farías P,Estay C,Oyarzun-Ampuero F,Herrera-Molina R,Paula-Lima A,Ardiles ÁO,Hidalgo C,Adasme T,Muñoz P

更新日期：2020-06-26 00:00:00

abstract：:Four new xanthene derivatives, penicixanthenes A-D (1-4), and one known compound 5 were isolated from a marine mangrove endophytic fungus Penicillium sp. JY246 that was obtained from the stem of Ceriops tagal. Their structures were determined by detailed NMR, MS spectroscopic data, modified Mosher's method, and calcul...

journal_title：Marine drugs

authors： Bai M,Zheng CJ,Nong XH,Zhou XM,Luo YP,Chen GY

更新日期：2019-11-20 00:00:00

abstract：:A bioassay guided fractionation of the ethyl acetate extract from culture broths of the strain Streptomyces zhaozhouensis CA-185989 led to the isolation of three new polycyclic tetramic acid macrolactams (1-3) and four known compounds. All the new compounds were structurally related to the known Streptomyces metabolit...

journal_title：Marine drugs

authors： Lacret R,Oves-Costales D,Gómez C,Díaz C,de la Cruz M,Pérez-Victoria I,Vicente F,Genilloud O,Reyes F

更新日期：2014-12-29 00:00:00

abstract：:Preliminary biological investigation of a collection of Comorian soft corals resulted in the selection of two specimens, one of Sarcophyton and the other of Lobophytum, on the basis of their toxicity on larvae of the brine shrimp (Artemia salina) and inhibition of acetylcholinesterase, respectively. Bioassay-guided fr...

journal_title：Marine drugs

authors： Bonnard I,Jhaumeer-Laulloo SB,Bontemps N,Banaigs B,Aknin M

更新日期：2010-02-23 00:00:00

abstract：:Oxidative stress contributes to chronic inflammatory processes implicated in aging, referred to as "inflamm-aging." In this study, the potential anti-inflammatory and anti-aging effects of a pigment-protein complex (PPC) from Chlorella pyrenoidosa were investigated using lipopolysaccharide (LPS)-stimulated RAW 264.7 m...

journal_title：Marine drugs

authors： Zhang R,Chen J,Mao X,Qi P,Zhang X

更新日期：2019-10-16 00:00:00

abstract：:The development and use of topical microbicides potentially offers an additional strategy to reduce the spread of the Human Immunodeficiency Virus (HIV). Carbohydrate-binding agents (CBAs) that show specificity for high mannose carbohydrates on the surface of the heavily glycosylated envelope of HIV are endowed with p...

journal_title：Marine drugs

authors： Huskens D,Schols D

更新日期：2012-07-01 00:00:00

abstract：:Omega-3 long-chain polyunsaturated fatty acids (LC-PUFAs), such as eicosapentaenoic acid (EPA) (20:5n-3) and docosahexaenoic acid (DHA) (22:6n-3), are considered essential for human health. Microorganisms are the primary producers of omega-3 fatty acids in marine ecosystems, representing a sustainable source of these ...

journal_title：Marine drugs

authors： Estupiñán M,Hernández I,Saitua E,Bilbao ME,Mendibil I,Ferrer J,Alonso-Sáez L

更新日期：2020-02-01 00:00:00

abstract：:This study aimed to investigate the cardiovascular effects elicited by Dictyota pulchella, a brown alga, using in vivo and in vitro approaches. In normotensive conscious rats, CH(2)Cl(2)/MeOH Extract (CME, 5, 10, 20 and 40 mg/kg) from Dictyota pulchella produced dose-dependent hypotension (-4 ± 1; -8 ± 2; -53 ± 8 and ...

journal_title：Marine drugs

authors： Queiroz TM,Machado NT,Furtado FF,Oliveira-Filho AA,Alustau MC,Figueiredo CS,Miranda GE,Barbosa-Filho JM,Braga VA,Medeiros IA

更新日期：2011-01-01 00:00:00

abstract：:Eight new compounds, sinulolides A-H (1-8), along with two known compounds, α-methoxy-2,3-dimethyl-butenolide (9) and sinularone D (10), were isolated from the soft coral Sinularia sp. The structures of these compounds were elucidated on the basis of extensive spectroscopic analysis. The absolute configurations were d...

journal_title：Marine drugs

authors： Yang B,Wei X,Huang J,Lin X,Liu J,Liao S,Wang J,Zhou X,Wang L,Liu Y

更新日期：2014-10-23 00:00:00

abstract：:Crude extracts and column fractions from the red algae Asparagopsis taxiformis and A. armata from the Strait of Messina (Italy) were screened for the production of antimicrobial compounds. Extracts from both species revealed remarkable antiprotozoal activity against Leishmania, revealing such algae as a great source o...

journal_title：Marine drugs

authors： Genovese G,Tedone L,Hamann MT,Morabito M

更新日期：2009-08-11 00:00:00

abstract：:N,N-Didesmethylgrossularine-1 (DDMG-1), a compound with a rare alpha-carboline structure, was isolated from an Indonesian ascidian Polycarpa aurata as responsible for the observed inhibitory activity against TNF-alpha production in lipopolysaccharide-stimulated murine macrophage-like RAW264.7 cells. DDMG-1 inhibited t...

journal_title：Marine drugs

authors： Oda T,Lee JS,Sato Y,Kabe Y,Sakamoto S,Handa H,Mangindaan RE,Namikoshi M

更新日期：2009-11-17 00:00:00

abstract：:Cyanobacteria are photosynthetic microorganisms that colonize diverse environments worldwide, ranging from ocean to freshwaters, soils, and extreme environments. Their adaptation capacities and the diversity of natural products that they synthesize, support cyanobacterial success in colonization of their respective ec...

journal_title：Marine drugs

authors： Demay J,Bernard C,Reinhardt A,Marie B

更新日期：2019-05-30 00:00:00

abstract：:Global incidence of type 2 diabetes has escalated over the past few decades, necessitating a continued search for natural sources of enzyme inhibitors to offset postprandial hyperglycemia. The objective of this study was to evaluate coastal Alaskan seaweed inhibition of α-glucosidase and α-amylase, two carbolytic enzy...

journal_title：Marine drugs

authors： Kellogg J,Grace MH,Lila MA

更新日期：2014-10-22 00:00:00

abstract：:Sargassum horneri (S. horneri), an edible brown alga, has been proposed as a functional food with an improvement effect on abnormal skin immune responses. The present study investigates the anti-allergic effect of an ethanol extract from S. horneri (SHE) on immunoglobulin E (IgE)/bovine serum albumin (BSA)-mediated ac...

journal_title：Marine drugs

authors： Han EJ,Kim HS,Sanjeewa KKA,Jung K,Jee Y,Jeon YJ,Fernando IPS,Ahn G

更新日期：2020-11-26 00:00:00

abstract：:Antimicrobial peptides (AMPs) are not only cytotoxic towards host pathogens or cancer cells but also are able to act as immunomodulators. It was shown that some human and non-human AMPs can interact with complement proteins and thereby modulate complement activity. Thus, AMPs could be considered as the base for comple...

journal_title：Marine drugs

authors： Krenev IA,Umnyakova ES,Eliseev IE,Dubrovskii YA,Gorbunov NP,Pozolotin VA,Komlev AS,Panteleev PV,Balandin SV,Ovchinnikova TV,Shamova OV,Berlov MN

更新日期：2020-12-10 00:00:00

abstract：:The 7-Acetylsinumaximol B (7-AB), a bioactive cembranoid, was originally discovered from aquaculture soft coral Sinularia sandensis. The current study investigated the anti-proliferative property of 7-AB towards the NCI-N87 human gastric cancer cell line. An MTT cell proliferative assay was applied to evaluate cell su...

journal_title：Marine drugs

authors： Tsai TC,Lai KH,Su JH,Wu YJ,Sheu JH

更新日期：2018-03-26 00:00:00

abstract：:Water-soluble sulfated polysaccharides isolated from two red algae Sphaerococcus coronopifolius (Gigartinales, Sphaerococcaceae) and Boergeseniella thuyoides (Ceramiales, Rhodomelaceae) collected on the coast of Morocco inhibited in vitro replication of the Human Immunodeficiency Virus (HIV) at 12.5 μg/mL. In addition...

journal_title：Marine drugs

authors： Bouhlal R,Haslin C,Chermann JC,Colliec-Jouault S,Sinquin C,Simon G,Cerantola S,Riadi H,Bourgougnon N

更新日期：2011-01-01 00:00:00

abstract：:Death-associated protein kinase 1 (DAPK1) expression induced by diverse death stimuli mediates apoptotic activity in various cancers, including ovarian cancer. In addition, mutual interaction between the tumor suppressor p53 and DAPK1 influences survival and death in several cancer cell lines. However, the exact role ...

journal_title：Marine drugs

authors： Park GB,Jeong JY,Kim D

更新日期：2019-07-12 00:00:00