Application of the avidin-biotin immunohistochemical method for the diagnosis of alveolar hydatid disease from tissue sections.

Abstract:

:The avidin-biotin immunohistochemical (ABC) method was applied to the diagnosis of alveolar hydatid disease in patients from the hyperendemic region of western Alaska. The test was specific for larval cestodes of the genus Echinococcus, and exhibited high sensitivity. A negative reaction was obtained in all cases in which spontaneous death of the larval cestode had occurred. Results were inconsistent in sections of lesions from patients who had received long-term therapy with mebendazole, because of the persistence of antigens for a considerable time following the death of the parasite.

authors

Condon J,Rausch RL,Wilson JF

doi

10.1016/0035-9203(88)90219-2

subject

Has Abstract

pub_date

1988-01-01 00:00:00

pages

731-5

issue

5

eissn

0035-9203

issn

1878-3503

journal_volume

82

pub_type

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