Abstract:
:Normal tension glaucoma is a variant of primary open angle glaucoma. It is characterized by normal intraocular pressure. Although there are several pathophysiological explanations (e. g. vascular dysregulation, the role of the lamina cribrosa), none of these explanations can fully explain its pathophysiology. The optic nerve is a white matter tract of the brain. It is surrounded by cerebrospinal fluid on its whole length. Neuroradiological examinations hint at a neurodegenerative origin of normal tension glaucoma. Impaired cerebrospinal fluid dynamics and reduced clearance of Aβ amyloid might play a role in this process. The lymphatic and the glymphatic system are thought to be essentially involved. :Das Normaldruckglaukom ist eine Variante des Offenwinkelglaukoms, das durch einen normalen Augendruck charakterisiert ist. Obwohl verschiedene pathophysiologische Erklärungen existieren (vaskuläre Dysregulation, Rolle der Lamina cribrosa) kann keine Theorie die Pathophysiologie schlüssig erklären. Der Sehnerv ist ein weißer Hirnfaszikel. Er ist auf seiner ganzen Länge von Liquor cerebrospinalis umspült. Auf der Basis von neuroradiologischen Untersuchungen vermutet man, dass ein Normaldruckglaukom aufgrund eines neurodegenerativen Prozesses entstehen kann. Eine ungenügende Liquordynamik kann dabei eine Rolle spielen, indem toxische Substanzen wie Aβ-Lipoprotein insuffizient aus dem Liquor entfernt werden. Dabei kommt dem lymphatischen und glymphatischen System eine wesentliche Rolle zu.
journal_name
Klin Monbl Augenheilkdjournal_title
Klinische Monatsblatter fur Augenheilkundeauthors
Killer HEdoi
10.1055/a-0809-5692subject
Has Abstractpub_date
2019-02-01 00:00:00pages
142-144issue
2eissn
0023-2165issn
1439-3999journal_volume
236pub_type
杂志文章abstract:BACKGROUND:About 3-10% of patients suffering from metastatic disease develop metastatic choroidal tumors. In this case report ocular symptoms were the first sign of a systemic malignancy. CASE REPORT:A 65-year old man complained of an increasing painful redness of his left eye. He showed a white mass with 10 mm in thi...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2000-10578
更新日期:2000-05-01 00:00:00
abstract::Several authors regard early vitrectomy as the best guarantee of success in cases of severe ocular injury. The present authors reviewed their own group of 27 patients, which included 13 cases with intraocular foreign bodies, 6 cases of blunt trauma and 8 with perforating injuries. Aside from cases which later develope...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1046190
更新日期:1990-05-01 00:00:00
abstract:BACKGROUND:Vitamin A, the fat soluble vitamin, must be supplied orally before resorption in the mucosa of the small intestine and storage in the liver. Vitamin A deficiency can cause alterations in the anterior segment of the eye, from Bitot spots, which are reversible, to irreversible keratomalacia. PATIENTS AND METH...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1045496
更新日期:1994-08-01 00:00:00
abstract:BACKGROUND:The evaluation of the anterior ocular chamber sections along the optical axis/axis of vision has been carried out using single-line partial coherence interferometry for many years. Now, new technologies such as the Scheimpflug-technique of the Pentacam (Oculus Optikgeräte GmbH, Wetzlar) and the optical coher...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-0028-1109367
更新日期:2009-06-01 00:00:00
abstract::Three hundred twenty-three eyes enucleated because of intraocular tumor were studied. The microscopic features were compared with survival data from 6 to 21 years after surgery, thus permitting the prognostic value of certain findings to be determined. Of the tumors, 299 were malignant melanomas of the choroid (262 ey...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1055271
更新日期:1982-12-01 00:00:00
abstract::Catalase may provide protection against photochemical action of superoxide radicals and hydrogen peroxide. The authors tried to measure its activity in freshly enucleated calf eyes before and after argon laser irradiation. It was established by iodometric titration that catalase activity was reduced after irradiation ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1050720
更新日期:1986-06-01 00:00:00
abstract::In the ERG the b-wave and the oscillatory potentials are reduced or nonrecordable in ischemic retinopathy. The photopic b-wave appeared to be more sensitive than the scotopic b-wave. In the EOG the slow oscillation is reduced. These clinical observations are in accordance with the results of experimental studies in rh...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1979-03-01 00:00:00
abstract::Using the CANON CG 6 60 Z wide-angle fundus camera, fluorescein angiographic examinations of the fundus periphery were performed on 90 diabetic patients presenting with exudative diabetic maculopathy. The peripheral angiogram demonstrates that perimacular hyperpermeability - the main cause of diabetic maculopathy - is...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1050901
更新日期:1985-03-01 00:00:00
abstract::A 19-year-old woman presented in the latent phase of secondary syphilis with chronic bilateral anterior uveitis and a slightly elevated optic disk with indistinct margins in the left eye; this was interpreted as a meningitis of the optic nerve. Serologic examination revealed the syphilitic infection, which had not pre...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1050356
更新日期:1987-03-01 00:00:00
abstract:BACKGROUND:Subretinal hemorrhage in age related macular degeneration (AMD) usually causes acute visual loss and is associated with poor visual prognosis. In order to prevent retinal damage and to perform laser treatment of the underlying choroidal neovascularization (CNV) the subretinal hemorrhage has to be removed fro...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2000-10513
更新日期:2000-01-01 00:00:00
abstract::In this paper the author describes a modification of iridocyclectomy. Before opening the bulbus and removing the malignant melanoma, a lamellar scleral flap is formed with its base at the limbus. After extirpation of the tumor the area is "plastically" covered with this flap. This modification was used on 5 patients; ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1983-12-01 00:00:00
abstract::Background The aim of this retrospective study was to evaluate the rotational stability and the refractive outcome of two different toric IOLs. Methods This study included 41 eyes with corneal astigmatism greater than 1.5 diopters (D). All patients underwent surgery in the Department of Ophthalmology at Hietzing Hospi...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-0043-100656
更新日期:2017-06-01 00:00:00
abstract::Varying degrees of deficient color perception along the Deutan axis within one family have been studied and presented. All seven family members exhibit manifest color blindness. The question of the phenotype among heterozygotic females is discussed on the basis of the data found by anomaloscope testing and the hue tes...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1976-01-01 00:00:00
abstract:BACKGROUND:Laser therapy is an important treatment option in retinal diseases, especially in cases of vascular involvement. Most approaches are based on coagulation of retinal structures. As there is increasing use of agents targetting vascular endothelial growth factor in the treatment of macular diseases, indications...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章,评审
doi:10.1055/s-0042-123831
更新日期:2018-12-01 00:00:00
abstract::Iatrogenic damage to the orbital fascial system during strabismus surgery may lead to adherences with resulting problems of motility. To prevent new adherences in revisional surgery, several materials were tried, with varying degrees of success. The authors tested Polyglactin 910, popular as a suture material in strab...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1050257
更新日期:1988-09-01 00:00:00
abstract:BACKGROUND:The optic nerve sheath meningioma usually presents with a diffuse atrophy of the disc and a diffuse depression of the visual field. Applying this rule too rigidly can lead to a false diagnosis. PATIENT:A 45y-old-woman presented with atrophy of the upper disc and a corresponding altitudinal field defect in h...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1035368
更新日期:1995-09-01 00:00:00
abstract:PURPOSE:The aim of this study was to compare the different calculation methods in large patient collectives, including eyes with extreme axial lengths. METHOD AND MATERIAL:The prediction errors of the Haigis, SRK/T, Hoffer-Q and Holladay formulae and of the OKULIX ray-tracing are compared in 2888 normal eyes implanted...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1027966
更新日期:2009-02-01 00:00:00
abstract::The panel of therapeutic options available for the treatment of retroviral disorders has expanded explosively in recent years with the result that it has now become possible to reconstitute the immune function of individuals with advanced HIV-disease to a remarkable degree. The ophthalmologist is thus confronted with ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章,评审
doi:10.1055/s-2000-10520
更新日期:2000-02-01 00:00:00
abstract::After a discussion of the pathomechanism of skull trauma by a blow leading to chiasmal lesion, frontobasal injuries of the skull are considered; it is shown that typical defects of the visual field resulting from chiasmal damage can be revealed not only in cases of serious industrial or traffic accidents with brain co...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1976-11-01 00:00:00
abstract::The causes of hypo- and hyperchromic heterochromia were analysed in 94 patients. The hypochromic forms were the commonest, especially the Fuchs-Herrenschwandt heterochromia, and heterochromia simplex. Also after degenerative diseases and accidents appears almost exclusively hypochromic heterochromia. Causes of hyperch...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1975-04-01 00:00:00
abstract::Computerized threshold perimetry of the central 30 degrees was performed on 69 eyes of 36 patients (men and women of all age groups and with different types of diabetes) one day before and one month after panretinal photocoagulation by argon laser. An average of 900 spots were placed in a chessboard pattern in three s...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1050103
更新日期:1988-03-01 00:00:00
abstract::During his researches on colour-vision Goethe has examined two colour blind students. The reports and the colour tests made by Goethe himself are mostly preserved. Due to the colour confusions in the whole purple zone Goethe decided that the subjects were blue blind. During the 19th century-- however--the supposition ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 传,历史文章,杂志文章
doi:
更新日期:1989-12-01 00:00:00
abstract:UNLABELLED:A new low vision aid (LVA)-the Low Vision Enhancement System or LVES, which were as developed at the Johns Hopkins University in Baltimore, is now commercially available. This instrument allows a magnification up to 10 times with control of contrast and luminance while the field of view is very large: 60 x 4...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1035025
更新日期:1997-02-01 00:00:00
abstract:PURPOSE:To analyse the impact of cataract surgery after filtering operation on the intraocular pressure (IOP) due to primary open angle glaucoma (pOAG) versus secondary open angle glaucoma in pseudoexfoliation syndrome (PEX). The regulation of IOP was evaluated on the basis of criteria of advanced glaucoma intervention...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2002-26725
更新日期:2002-03-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to evaluate the functional outcome of Brilliant Blue G (BBG) and the staining properties in macular surgery. METHODS:BBG was applied during vitrectomy for macular holes (n = 21) or epiretinal membranes (n = 18) in a prospective, non-comparative consecutive series of patients (Brilli...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-0031-1273351
更新日期:2011-08-01 00:00:00
abstract:INTRODUCTION:Until now, venous pressure within the eye has widely been equated with intraocular pressure (IOP). Measurements with dynamometers calibrated in instrument units or in force showed that the retinal venous pressure (RVP) may be higher than the IOP in glaucoma patients. In this study, the RVP was measured wit...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/a-1318-9991
更新日期:2021-01-12 00:00:00
abstract::The examination of near heterophoria with a heterometer using a large series of test plates presented "free-sighted" (i.e., not hindered by optical or mechanical means) enables a more comprehensive analysis to be made than has so far been achieved with other instruments. The principal components of the instruments are...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1050156
更新日期:1988-05-01 00:00:00
abstract:BACKGROUND:Laser peripheral iridotomy is a useful method in primary angle-closure eyes to prevent angle-closure attack and development of glaucomatous optic nerve damage. The aim of this study was to quantify morphological changes after LPI and their impact on intraocular pressure, and to evaluate predictive parameters...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 临床试验,杂志文章
doi:10.1055/s-0035-1545793
更新日期:2015-04-01 00:00:00
abstract:BACKGROUND:The alternating prism and cover test is the conventional test for the measurement of the angle of strabismus. The error induced by the prismatic effect of glasses is typically about 27-30%/10 D. Alternatively, the angle of strabismus can be measured with methods based on Purkinje reflex positions. This study...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1034870
更新日期:1998-04-01 00:00:00
abstract::Gene therapy raised euphoric expectations in the past that have yet to be met and have even been lowered due to the absence of concrete clinical successes and the occurrence of some tragic incidents. In spite of the great future potential of gene therapy, numerous pilot studies in this field will probably be discontin...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章,评审
doi:10.1055/s-2003-44610
更新日期:2003-11-01 00:00:00