Hepatoprotective effects of phosphatidylserine liposomes on carbon tetrachloride-induced hepatotoxicity in rats.

abstract：:We studied how deficiency in lamins A/C and lamina-associated polypeptide 2α (Lap2α) affects DNA repair after irradiation. A-type lamins and Lap2α were not recruited to local DNA lesions and did not accumulate to γ-irradiation-induced foci (IRIF), as it is generally observed for well-known marker of DNA lesions, 53BP1...

journal_title：Journal of cellular biochemistry

authors： Bártová E,Legartová S,Krejčí J,Řezníčková P,Kovaříková AS,Suchánková J,Fedr R,Smirnov E,Hornáček M,Raška I

更新日期：2018-11-01 00:00:00

abstract：:Diclofenac is the most commonly used phenylacetic acid derivative non-steroidal anti-inflammatory drug (NSAID) that demonstrates significant analgesic, antipyretic, and anti-inflammatory effects. Several epidemiological studies have demonstrated anti-proliferative activity of NSAIDs and examined their apoptotic induct...

journal_title：Journal of cellular biochemistry

authors： Amanullah A,Upadhyay A,Chhangani D,Joshi V,Mishra R,Yamanaka K,Mishra A

更新日期：2017-05-01 00:00:00

abstract：:We have partially purified and characterized an 87 kDa gelatinase activity expressed in later stage sea urchin embryos. Cleavage activity was specific for gelatin and no cleavage of sea urchin peristome type I collagen, bovine serum albumin or casein was detected. Magnesium and Zn2+ inhibited the gelatinase and Ca2+ p...

journal_title：Journal of cellular biochemistry

authors： Robinson JJ

更新日期：1997-09-01 00:00:00

abstract：:There is a well-known relationship between the cholinergic system and learning, memory, and other common cognitive processes. The process for researching and developing new drugs has lead researchers to repurpose older ones. This study investigated the effects of ebselen on the activity of acethylcholinesterase (AChE)...

journal_title：Journal of cellular biochemistry

authors： Martini F,Pesarico AP,Brüning CA,Zeni G,Nogueira CW

更新日期：2018-07-01 00:00:00

abstract：:We previously suggested that keratinocyte releasable factors might modulate the wound healing process by regulating the expression of key extracellular matrix components such as collagenase (matrix metalloproteinase-1) and type I collagen in fibroblasts. The first one, we called it keratinocyte-derived anti-fibrogenic...

journal_title：Journal of cellular biochemistry

authors： Chavez-Muñoz C,Hartwell R,Jalili RB,Jafarnejad SM,Lai A,Nabai L,Ghaffari A,Hojabrpour P,Kanaan N,Duronio V,Guns E,Cherkasov A,Ghahary A

更新日期：2012-08-01 00:00:00

abstract：:Breast cancer, the most common cancer in women worldwide, is associated with high mortality. The long non-coding RNAs (lncRNAs) with a little capacity of coding proteins is playing an increasingly important role in the cancer paradigm. Accumulating evidences demonstrate that lncRNAs have crucial connections with breas...

journal_title：Journal of cellular biochemistry

authors： He Y,Li X,Meng Y,Fu S,Cui Y,Shi Y,Du H

更新日期：2019-10-01 00:00:00

abstract：:This study aimed to elucidate the precise mechanisms underlying the protective effects of phosphoseryl-tRNA kinase (PSTK) against cisplatin-induced podocyte injury. PSTK overexpression and knockdown vectors were generated and transfected into murine podocyte cells-5. PSTK levels were measured, and transcriptome sequen...

journal_title：Journal of cellular biochemistry

authors： Zheng D,Zhao Y,Liu L,Sun X,Xia Y,Sun L,Xie K

更新日期：2019-06-01 00:00:00

abstract：:Several gap junction connexins have been shown to be essential for appropriate placental development and function. It is known that the expression and distribution of connexins change in response to environmental oxygen levels. The placenta develops under various oxygen levels, beginning at a low oxygen tension of app...

journal_title：Journal of cellular biochemistry

authors： Otto T,Gellhaus A,Lüschen N,Scheidler J,Bendix I,Dunk C,Wolf N,Lennartz K,Köninger A,Schmidt M,Kimmig R,Fandrey J,Winterhager E

更新日期：2015-12-01 00:00:00

abstract：:Emerging evidence suggests that long noncoding RNAs (lncRNAs) are involved in many biological processes, such as cell growth, differentiation, apoptosis, and autophagy. Metastasis-associated lung adenocarcinoma transcript 1 (MALAT1), highly expressed in endothelial cells, is well conserved and implicated in endothelia...

journal_title：Journal of cellular biochemistry

authors： Li S,Pan X,Yang S,Ma A,Yin S,Dong Y,Pei H,Bi X,Li W

更新日期：2019-03-01 00:00:00

abstract：:Wnt/β-catenin signaling regulates various cellular events involved in the proliferation and differentiation and these events are affected sensitively by applying to mechanical stimuli. However, the mechanisms by which mechanical force stimulates cardiomyogenesis are not extensively explored. In this study we investiga...

journal_title：Journal of cellular biochemistry

authors： Heo JS,Lee JC

更新日期：2011-07-01 00:00:00

abstract：:Induction of definitive endoderm (DE) cells is a prerequisite for the whole process of embryonic stem (ES) cells differentiating into hepatic or pancreatic progenitor cells. We have established an efficient method to induce mouse ES cell-derived DE cells in suspension embryonic body (EB) culture. Similar to previous s...

journal_title：Journal of cellular biochemistry

authors： Li F,He Z,Li Y,Liu P,Chen F,Wang M,Zhu H,Ding X,Wangensteen KJ,Hu Y,Wang X

更新日期：2011-04-01 00:00:00

abstract：:Scaffolds porosity has an important role in in vitro and in vivo differentiation process of stem cells with given the amount of space available to the cells to proliferate and differentiate. In the present study, chitosan with three porosities including 10%, 15%, and 20% that created by gelatin were used for investiga...

journal_title：Journal of cellular biochemistry

authors： Ardeshirylajimi A,Delgoshaie M,Mirzaei S,Khojasteh A

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVE:Osteoarthritis (OA) is a progressive and disabling disorder, characterized by synovial inflammation and joint effusion. This study aimed to explore the role of stanniocalcin-1 (STC1) in the development of OA by regulating the survival and inflammation of fibroblast-like synovial (FLS) cells. METHODS:Microarr...

journal_title：Journal of cellular biochemistry

authors： Wu Y,Li Z,Jia W,Li M,Tang M

更新日期：2019-06-01 00:00:00

abstract：:The role of excision repair cross-complimentary group 1 (ERCC1) gene polymorphisms in breast and ovarian cancer development has long been controversial and existing data were inconsistent. Here, we conducted a comprehensive meta-analysis to better clarify the association. Case-control studies published from December 2...

journal_title：Journal of cellular biochemistry

authors： Yang F,Mu X,Bian C,Zhang H,Yi T,Zhao X,Lin X

更新日期：2019-09-01 00:00:00

abstract：:Extracellular matrix metalloproteinases (MMPs) are activated in dilated cardiomyopathic (DCM) hearts [Tyagi et al. (1996): Mol Cell Biochem 155:13-21]. To examine whether the MMP activation is occurring at the gene expression level, we performed differential display mRNA analysis on tissue from six dilated cardiomyopa...

journal_title：Journal of cellular biochemistry

authors： Tyagi SC,Kumar S,Voelker DJ,Reddy HK,Janicki JS,Curtis JJ

更新日期：1996-11-01 00:00:00

abstract：:Stroke is one of the most destructive complications of sickle cell disease (SCD), and SCD is also the most common cause of childhood stroke. Sickle cell stroke is complex and has a genetic endothelial basis. Here, we further investigated this genetic basis using weighted gene coexpression network analysis. This system...

journal_title：Journal of cellular biochemistry

authors： Liu FF,Wang J,Hu F,Wei Q,Li K

更新日期：2019-09-01 00:00:00

abstract：:Apoptosis has been described extensively in tooth development, which is under tight control of multiple apoptosis regulators, including anti-apoptotic protein Bcl-2. However, it is totally unclear how Bcl-2 is related to odontogenesis, especially dentinogenesis. Using a transgenic mouse Col2.3Bcl-2 in which human Bcl-...

journal_title：Journal of cellular biochemistry

authors： Zhang W,Ju J,Gronowicz G

更新日期：2010-10-01 00:00:00

abstract：:Nowadays, increased use of nanomaterials in industry and biomedicine poses potential risks to human health and the environment. Studying their possible toxicological effects is therefore of great significance. The present investigation was designed to examine the status of oxidative stress induced by nanoparticles (NP...

journal_title：Journal of cellular biochemistry

authors： Soltani A,Kahkhaie KR,Haftcheshmeh SM,Jalali Nezhad AA,Akbar Boojar MM

更新日期：2018-11-28 00:00:00

abstract：:Platelet-derived growth factor (PDGF) has been implicated in smooth muscle cell (SMC) proliferation, a key event in the development of myointimal hyperplasia in vascular grafts. Recent evidence suggests that the PDGF receptor (PDGFR) tyrosine kinase inhibitor, imatinib, can prevent arterial proliferative diseases. Bec...

journal_title：Journal of cellular biochemistry

authors： Li L,Blumenthal DK,Masaki T,Terry CM,Cheung AK

更新日期：2006-12-15 00:00:00

abstract：:Loss of mechanical stress causes bone loss. However, the mechanisms underlying the unloading-induced bone loss are largely unknown. Here, we examined the effects of gold-thioglucose (GTG) treatment, which destroys ventromedial hypothalamus (VMH), on unloading-induced bone loss. Unloading reduced bone volume in control...

journal_title：Journal of cellular biochemistry

authors： Hino K,Nifuji A,Morinobu M,Tsuji K,Ezura Y,Nakashima K,Yamamoto H,Noda M

更新日期：2006-10-15 00:00:00

abstract：:3,6-Anhydro-l-galactose (l-AHG) is a bioactive sugar that is a major component of agarose. Recently, l-AHG was reported to have anti-melanogenic potential in human epidermal melanocytes (HEMs) and B16F10 melanoma cells; however, its underlying molecular mechanisms remain unknown. At noncytotoxic concentrations, l-AHG ...

journal_title：Journal of cellular biochemistry

authors： Kim JH,Kim DH,Cho KM,Kim KH,Kang NJ

更新日期：2018-09-01 00:00:00

abstract：:Members of the transforming growth factor-β (TGF-β) family function through Smad-dependent and Smad-independent pathways. The Smad-dependent pathway is stimulated through the phosphorylation of receptor-regulated Smad (R-Smad) and inhibited through the dephosphorylation of R-Smad or the gene induction of inhibitory Sm...

journal_title：Journal of cellular biochemistry

authors： Katakawa Y,Funaba M,Murakami M

更新日期：2016-08-01 00:00:00

abstract：:Resveratrol, a polyphenol found in fruits, has been demonstrated to activate Sir2. Though many studies have demonstrated that resveratrol can activate SIRT1, whether it has effect on other sirtuins (SIRT2-7) are unknown. The present study shows that exposure of H9c2 cells to 50 microM H(2)O(2) for 6 h caused a signifi...

journal_title：Journal of cellular biochemistry

authors： Yu W,Fu YC,Zhou XH,Chen CJ,Wang X,Lin RB,Wang W

更新日期：2009-07-01 00:00:00

abstract：:Fluorescent proteins have enabled the color-coding of cells growing in vivo. Noninvasive imaging of cells expressing fluorescent proteins has allowed the real-time determination of the behavior of cancer cells, the progression of infection, the differentiation of stem cells, and interaction of stromal and cancer cells...

journal_title：Journal of cellular biochemistry

authors： Hoffman RM

更新日期：2017-09-01 00:00:00

abstract：:Cells release exosomes to transfer various molecules to other cells. Exosomes are involved in a number of physiological and pathological processes. They are emerging great potential utility for diseases diagnosis and treatment recently. However, the internalization and intracellular trafficking of exosomes have not be...

journal_title：Journal of cellular biochemistry

authors： Tian T,Wang Y,Wang H,Zhu Z,Xiao Z

更新日期：2010-10-01 00:00:00

abstract：:Mouse embryonic fibroblast (MEF) cells prepared from transgenic mice overexpressing a cancer-specific and growth-related cell surface NADH oxidase with protein disulfide-thiol interchange activity grew at rates approximately twice those of wild-type embryonic fibroblast cells. Growth of transgenic MEF cells overexpres...

journal_title：Journal of cellular biochemistry

authors： Yagiz K,Wu LY,Kuntz CP,James Morré D,Morré DM

更新日期：2007-05-15 00:00:00

abstract：:Multifidus muscle dysfunction is associated with the multifidus muscle injury (MMI), which ultimately result in the low-back pain. Increasing evidence shows that microRNAs (miRs) may be involved in multifidus muscle dysfunction. In this study, we tested the hypothesis that downregulation of let-7b-5p may inhibit the m...

journal_title：Journal of cellular biochemistry

authors： Yu HM,Yao XD,Zhang RM,Zhuang HF,Wang PW,Li YZ

更新日期：2018-11-01 00:00:00

abstract：:Osteoclasts are macrophage-derived polykaryons that degrade bone in an acidic extracellular space. This differentiation includes expression of proteinases and acid transport proteins, cell fusion, and bone attachment, but the sequence of events is unclear. We studied two proteins expressed at high levels only in the o...

journal_title：Journal of cellular biochemistry

authors： Blair HC,Sidonio RF,Friedberg RC,Khan NN,Dong SS

更新日期：2000-06-12 00:00:00

abstract：:Thymosin β-4 (Tβ4) is a ubiquitous protein, which has been suggested to regulate multiple cell signal pathways and a variety of cellular functions. However, the role Tβ4 plays in the cardiac microvascular endothelial cells (CMECs) under myocardial ischemia/reperfusion injury is currently unknown. Here we investigated ...

journal_title：Journal of cellular biochemistry

authors： Li Y,Zhu X,Liu X,Du A,Yu B

更新日期：2019-11-01 00:00:00

abstract：:Previous work from this laboratory indicates a role for the complement component C5 in neuroprotection against excitotoxicity. In the present study, we tested the hypothesis that the C5-derived anaphylatoxin C5a protects against kainic acid (KA)-induced neurodegeneration and investigated the mechanism of C5a neuronal ...

journal_title：Journal of cellular biochemistry

authors： Osaka H,Mukherjee P,Aisen PS,Pasinetti GM

更新日期：1999-06-01 00:00:00