Abstract:
:Exercise improves both physical and mental health and increases neurogenesis in the dendate gyrus (DG) of the hippocampus. The aim of this study was to examine whether exercising, as compared to no change in regular physical activity, would impact on hippocampal volume, and in particular the core hippocampal structures, DG and cornu ammonis (CA) subfields, and whether any changes would be moderated by age. Thirty nine previously sedentary healthy participants were randomized to either a standardized progressive aerobic exercise program or to "no change" for 16 weeks. Mental health including profile of mood states (POMS), was assessed before and every 4 weeks during the program. Magnetic resonance imaging to examine hippocampal subfields was carried out before and after the program. Aerobic exercise resulted in a significant improvement of the POMS item 'vigour' compared to those in the control group. Overall left hippocampal and left CA4-DG volumes increased significantly in the exercise group while no significant changes were seen in the control group. Older adults in the control group demonstrated significant reductions in CA4-DG subfields over the study, whereas older adults in the exercise group did not show volume decline. These findings reinforce the literature that exercise has a beneficial effect on mental health and can prevent age-related volume decline. Exercise to Improve Resilience, https://register.clinicaltrials.gov/prs/app/action/LoginUser?ts=1&cx=-jg9qo4 , NCT02541136, Rec Ref 2011/45/13.
journal_name
Brain Imaging Behavjournal_title
Brain imaging and behaviorauthors
Frodl T,Strehl K,Carballedo A,Tozzi L,Doyle M,Amico F,Gormley J,Lavelle G,O'Keane Vdoi
10.1007/s11682-019-00088-6subject
Has Abstractpub_date
2020-10-01 00:00:00pages
1577-1587issue
5eissn
1931-7557issn
1931-7565pii
10.1007/s11682-019-00088-6journal_volume
14pub_type
杂志文章abstract::Neuroscientific and psychological research posits that there are two transdiagnostic facets of anxiety: anxious arousal and anxious apprehension. Though these two facets of anxiety are distinct, they are often subsumed into one domain (e.g., trait anxiety). The primary goal of the current study was to delineate the re...
journal_title:Brain imaging and behavior
pub_type: 杂志文章
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journal_title:Brain imaging and behavior
pub_type: 杂志文章,评审
doi:10.1007/s11682-020-00336-0
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journal_title:Brain imaging and behavior
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journal_title:Brain imaging and behavior
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journal_title:Brain imaging and behavior
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journal_title:Brain imaging and behavior
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journal_title:Brain imaging and behavior
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journal_title:Brain imaging and behavior
pub_type: 临床试验,杂志文章
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journal_title:Brain imaging and behavior
pub_type: 杂志文章
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更新日期:2015-06-01 00:00:00
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journal_title:Brain imaging and behavior
pub_type: 杂志文章
doi:10.1007/s11682-015-9498-x
更新日期:2016-12-01 00:00:00
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journal_title:Brain imaging and behavior
pub_type: 杂志文章
doi:10.1007/s11682-017-9729-4
更新日期:2018-06-01 00:00:00
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journal_title:Brain imaging and behavior
pub_type: 杂志文章
doi:10.1007/s11682-014-9350-8
更新日期:2015-12-01 00:00:00
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journal_title:Brain imaging and behavior
pub_type: 杂志文章
doi:10.1007/s11682-016-9531-8
更新日期:2017-04-01 00:00:00
abstract::This study examined the reliability of high angular resolution diffusion tensor imaging (HARDI) data collected on a single individual across several sessions using the same scanner. HARDI data was acquired for one healthy adult male at the same time of day on ten separate days across a one-month period. Environmental ...
journal_title:Brain imaging and behavior
pub_type: 杂志文章
doi:10.1007/s11682-015-9425-1
更新日期:2016-06-01 00:00:00
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journal_title:Brain imaging and behavior
pub_type: 杂志文章
doi:10.1007/s11682-019-00071-1
更新日期:2020-08-01 00:00:00
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journal_title:Brain imaging and behavior
pub_type: 杂志文章
doi:10.1007/s11682-014-9291-2
更新日期:2015-06-01 00:00:00
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journal_title:Brain imaging and behavior
pub_type: 杂志文章
doi:10.1007/s11682-015-9467-4
更新日期:2016-09-01 00:00:00
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journal_title:Brain imaging and behavior
pub_type: 杂志文章
doi:10.1007/s11682-017-9724-9
更新日期:2018-06-01 00:00:00
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journal_title:Brain imaging and behavior
pub_type: 杂志文章
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pub_type: 杂志文章
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journal_title:Brain imaging and behavior
pub_type: 杂志文章
doi:10.1007/s11682-018-0022-y
更新日期:2020-04-01 00:00:00
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journal_title:Brain imaging and behavior
pub_type: 杂志文章
doi:10.1007/s11682-020-00322-6
更新日期:2020-07-25 00:00:00
abstract::Diffusion MRI (dMRI) is commonly used to map large axonal pathways in the white matter. Recent technical advances have also enabled dMRI to resolve the small and complex axonal and dendritic projections in the gray matter. This study investigated whether high-resolution dMRI can resolve the hippocampal neuronal projec...
journal_title:Brain imaging and behavior
pub_type: 杂志文章
doi:10.1007/s11682-019-00246-w
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journal_title:Brain imaging and behavior
pub_type: 杂志文章
doi:10.1007/s11682-015-9415-3
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journal_title:Brain imaging and behavior
pub_type: 杂志文章
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journal_title:Brain imaging and behavior
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journal_title:Brain imaging and behavior
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