Candida in the Respiratory Tract Potentially Triggers Galactomannan Positivity in Nonhematological Patients.

Abstract:

:BAL fluid samples from critically ill patients shared a rate of 29% false-positive galactomannan results. We aimed to determine whether Candida species abundance in BAL fluid causes galactomannan (GM) positivity. A total of 89 Candida culture-positive BAL fluid samples from patients without suspicion of invasive aspergillosis (IA) were analyzed. GM results were correlated with Candida species abundance, Candida species quantity, and patient data. Candida species quantities of ≥104/ml and Candida glabrata abundance were significantly associated with positive GM results. The added diagnostic value of GM in BAL fluid for diagnosing IA in critically ill patients is limited.

authors

Aigner M,Wanner M,Kreidl P,Lass-Flörl C,Lackner M

doi

10.1128/AAC.00138-19

subject

Has Abstract

pub_date

2019-05-24 00:00:00

issue

6

eissn

0066-4804

issn

1098-6596

pii

AAC.00138-19

journal_volume

63

pub_type

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