Upregulated lncRNA Gm2044 inhibits male germ cell development by acting as miR-202 host gene.

abstract：:Generation of induced pluripotent stem cells (iPSCs) by defined factors (OCT4, SOX2, C-MYC, and KLF4) from various human primary cells has been reported. Human fibroblasts have been widely used as a cellular source in reprogramming studies over recent decades. The original method of iPSC generation uses retro- or lent...

journal_title：Animal cells and systems

authors： Bang JS,Choi NY,Lee M,Ko K,Lee HJ,Park YS,Jeong D,Chung HM,Ko K

更新日期：2018-03-15 00:00:00

abstract：:Niemann-Pick type C disease (NP-C) is a fatal neurodegenerative disorder caused by a deficiency in the function of the NPC1 gene. Malfunction of this gene/protein leads to progressive accumulation of unesterified cholesterol and sphingolipids in many organs, including the brain. To date, drugs that target pivotal stag...

journal_title：Animal cells and systems

authors： Jeong MS,Bae JS,Jin HK

更新日期：2019-08-25 00:00:00

abstract：:The amyloid-β (Aβ) hypothesis has been the leading explanation for the pathogenesis of Alzheimer's disease (AD). The most common traits of AD are cognitive impairments and memory loss, which are associated with the accumulation of Aβ. Aβ aggregates activate glial cells, which in turn remove Aβ. Because microglia act a...

journal_title：Animal cells and systems

authors： Kim YS,Jung HM,Yoon BE

更新日期：2018-08-12 00:00:00

abstract：:Current parallel sequencing technologies generate biological sequence data explosively and enable omics studies that analyze collective biological features. The more omics data that is accumulated, the more they show the regulatory complexity of biological phenotypes. This high order regulatory complexity needs system...

journal_title：Animal cells and systems

authors： Jung GT,Kim KP,Kim K

更新日期：2020-01-30 00:00:00

abstract：:The microstructure, composition and mechanical properties of the rostrum in Cyrtotrachelus longimanus (JHC Fabre) were studied utilizing light, fluorescent, scanning electron microscopy (SEM) and energy-dispersive spectroscopy. SEM images show the morphological characteristics of rostrum's cross section; it is a typic...

journal_title：Animal cells and systems

authors： Li L,Guo C,Li X,Xu S,Han C

更新日期：2017-05-31 00:00:00

abstract：:To investigate distribution, habitat characteristics, and current conservation status of the endangered endemic species, rapid small gudgeon Microphysogobio rapidus (Cyprinidae), we surveyed a total of 79 sites from the historic records (20 sites) plus additional sites (59 sites) with good habitat conditions, analyzed...

journal_title：Animal cells and systems

authors： Hong YK,Sung HC,Ko MH,Kim KS,Bang IC

更新日期：2017-07-10 00:00:00

abstract：:Previously, we reported that endometrial stromal (ES) and endometrial epithelial (EE) cells did not attach to tenascin C, indicating the absence of active integrin α9β1 on the surface of mouse ES and EE cells. However, that study used recombinant tenascin C without fibronectin (FN) type III repeats interacting with in...

journal_title：Animal cells and systems

authors： Park HJ,Yun JI,Lee ST

更新日期：2020-08-05 00:00:00

abstract：:Autophagy is a major intracellular degradation process that plays an important role in cell survival, stress responses, nutrient sensing and development. Our previous studies have shown that Rg2, a triterpenoid saponin contained in ginseng, protects cells against UVB-induced genotoxicity by increasing DNA repair, in p...

journal_title：Animal cells and systems

authors： Chung Y,Jeong S,Choi HS,Ro S,Lee JS,Park JK

更新日期：2018-11-19 00:00:00

abstract：:To evaluate the effects of LncRNAZFAS1 on cell proliferation and tumor metastasis in non-small cell lung cancer (NSCLC), we detected the expression level of LncRNAZFAS1 in NSCLC-related tissues and cells. qRT-PCR results revealed that LncRNAZFAS1 in tumor tissues was significantly higher than that in normal lung tissu...

journal_title：Animal cells and systems

authors： Zhou Y,Hu XW,Yang SJ,Yu Z

更新日期：2020-03-02 00:00:00

abstract：:Phenological shifts of plants and animals due to climate change can vary among regions and species, requiring study of local ecosystems to understand specific impacts. The reproductive timing of insectivorous songbirds in temperate forests is tightly synchronized with peak prey abundance, and thus they can be suscepti...

journal_title：Animal cells and systems

authors： Jeong MS,Choi CY,Kim H,Lee WS

更新日期：2019-10-10 00:00:00

abstract：:This study aimed to explore the potential genes and pathways associated with bupivacaine-induced apoptosis. Human neuroblastoma cell line SH-SY5Y was used in this study. The effect of bupivacaine on cell viability of SH-SY5Y was detected by Cell Counting Kit-8. Transcriptome sequencing was performed for SH-SY5Y cells ...

journal_title：Animal cells and systems

authors： Wei P,Wang T,Han S,Ma G,Gao S,Yang Z

更新日期：2017-02-22 00:00:00

abstract：:Sorex mirabilis, a small insectivorous mammal, is a very rare, poorly known species distributed at high latitudes and altitudes of northeastern Asia. The occurrence of this species in the Republic of Korea was known from late 1990s. We found a new specimen from a location of a 50' lower latitude and 400 m lower altitu...

journal_title：Animal cells and systems

authors： Park SJ,Lee WS

更新日期：2019-01-03 00:00:00

abstract：:Gastric cancer is a leading cause of cancer death worldwide. Endoplasmic reticulum (ER) stress-induced apoptosis has been confirmed to be important in the treatment of gastric cancer. MiR-637 has recently been found to exert inhibitory effects on gastric cancer, and this study aimed to investigate whether miR-637 coul...

journal_title：Animal cells and systems

authors： Kong Q,Zhang Z,Liang Z

更新日期：2020-09-10 00:00:00

abstract：:Metagenomic analysis was carried out for the first time on the marine coastal invertebrates of South Korea. Samples collected from coastal areas of Korea were filtered through a 63 µm mesh, then their 18S rDNA V4 regions were amplified. High-throughput sequencing of PCR amplicons using Illumina MiSeq and BLAST against...

journal_title：Animal cells and systems

authors： Kim H,Kim H,Hwang HS,Kim W

更新日期：2016-12-30 00:00:00

abstract：:Endothelin-1 (ET-1) induces contraction, proliferation, and collagen synthesis of activated hepatic stellate cells and is a potent mediator of portal hypertension. Endothelin-converting enzyme-1 (ECE-1) generates ET-1 from the inactive precursor big-endothelin-1. The cellular distribution and activity of ECE-1 in the ...

journal_title：Animal cells and systems

authors： Cho TJ,Kim HJ,Cho J

更新日期：2019-06-09 00:00:00

abstract：:Igf2, H19, and Nctc1 are linked co-regulated genes on distal mouse chromosome 7. This locus is an important model both for studying mechanisms of monoallelic expression and for elucidating the role of cis-regulatory elements - enhancers and insulators - in organizing chromatin and gene expression across a large domain...

journal_title：Animal cells and systems

authors： Kim JY,Youn HY,Pfeifer K,Eun B

更新日期：2019-05-16 00:00:00

abstract：:Activin, a member of the transforming growth factor (TGF-β) superfamily, induces mesoderm, endoderm and neuro-ectoderm formation in Xenopus embryos. Despite several previous studies, the complicated gene regulatory network and genes involved in this induction await more elaboration. We identified expression of various...

journal_title：Animal cells and systems

authors： Umair Z,Kumar S,Rafiq K,Kumar V,Reman ZU,Lee SH,Kim S,Lee JY,Lee U,Kim J

更新日期：2020-11-27 00:00:00

abstract：:Betaine is a key metabolite of the methionine cycle and known for attenuating alcoholic steatosis in the liver. Recent studies have focused on the protection effect of betaine in mitochondrial regulation through the enhanced oxidative phosphorylation system. However, the mechanisms of its beneficial effects have not b...

journal_title：Animal cells and systems

authors： Jung Kim M

更新日期：2018-08-30 00:00:00