[Allergen-derived peptide: A promising approach in asthma].

Abstract:

:Severe asthma required high dose of corticosteroids combined with biotherapies to control more or less asthma symptoms and lead to the decrease of patients' quality of life on long term. Recent studies show that hypoallergenic peptides derived from allergen can prevent airway hyperresponsiveness, decrease Th2 response and also allergen-specific IgE in mouse models of allergic asthma. Even if some peptides mechanisms remain unknown, their fast efficacy with low doses of allergens make peptide immunotherapy a new promising approach in allergic asthma.

journal_name

Rev Mal Respir

authors

Klein M,Magnan A,Bouchaud G

doi

10.1016/j.rmr.2019.03.005

subject

Has Abstract

pub_date

2019-04-01 00:00:00

pages

442-446

issue

4

eissn

0761-8425

issn

1776-2588

pii

S0761-8425(19)30084-1

journal_volume

36

pub_type

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