Impact of levamisole in co-administration with benznidazole on experimental Chagas disease.

abstract：:Oligosaccharides are broadly present on Leishmania cell surfaces. They can be useful for the leishmaniases diagnosis and also helpful in identifying new cell markers for the disease. The disaccharide Galα1-3Galβ is the immunodominant saccharide in Leishmania cell surface and is the unique non-reducing terminal glycosp...

journal_title：Parasitology

authors： de Souza LMB,Thomaz Soccol V,Petterle RR,Bates MD,Bates PA

更新日期：2018-12-01 00:00:00

abstract：:Vitellogenin synthesis by the fat body has been monitored using in vitro culture and immunoprecipitation. This system was found to be efficient for measuring vitellogenin production in both non-infected Tenebrio molitor and those infected with Hymenolepis diminuta. In fat bodies from infected beetles, vitellogenin pro...

journal_title：Parasitology

authors： Webb TJ,Hurd H

更新日期：1996-04-01 00:00:00

abstract：:We examine the evolution of microparasites in response to the immune system of vertebrate hosts. We first describe a simple model for an acute infection. This model suggests that the within-host dynamics of the microparasite will be a 'race' between parasite multiplication and a clonally expanding response by the host...

journal_title：Parasitology

authors： Antia R,Lipsitch M

更新日期：1997-01-01 00:00:00

abstract：:The effects of a parasitic infection with the nematode Nippostrongylus brasiliensis on the degradation rates of cytoplasmic tRNA, rRNA and mRNA in rats have been investigated by measuring the renal excretion rates of the modified RNA catabolites N6-threoninocarbonyladenosine, pseudouridine and 7-methylguanine. Between...

journal_title：Parasitology

authors： Topp H,Duden R,Stephan U,Schöch G

更新日期：1998-02-01 00:00:00

abstract：:Ornithodoros moubata ticks were fed on blood infected with Babesia equi. However, the parasites were quickly cleared as evidenced by the disappearance of B. equi-specific ribosomal RNA from the ticks. We hypothesized that if the Babesia parasite can escape midgut-associated barriers a non-vector tick can become infect...

journal_title：Parasitology

authors： Battsetseg B,Matsuo T,Xuan X,Boldbaatar D,Chee SH,Umemiya R,Sakaguchi T,Hatta T,Zhou J,Verdida AR,Taylor D,Fujisaki K

更新日期：2007-01-01 00:00:00

abstract：:Prevention of heartworm disease caused by Dirofilaria immitis in domestic dogs and cats relies on a single drug class, the macrocyclic lactones (MLs). Recently, it has been demonstrated that ML-resistant D. immitis are circulating in the Mississippi Delta region of the USA, but the prevalence and impact of these resis...

journal_title：Parasitology

authors： Wolstenholme AJ,Evans CC,Jimenez PD,Moorhead AR

更新日期：2015-09-01 00:00:00

abstract：:Blastocystis SSU-rDNA sequence data from 317 captive and free-living non-human primates (NHPs) representing 30 genera of apes, Old and New World (OW and NW) monkeys and prosimians were analysed to investigate subtype (ST) and allele distribution among hosts. Excluding 20 mixed ST infections, 27% of the sequences belon...

journal_title：Parasitology

authors： Alfellani MA,Jacob AS,Perea NO,Krecek RC,Taner-Mulla D,Verweij JJ,Levecke B,Tannich E,Clark CG,Stensvold CR

更新日期：2013-07-01 00:00:00

abstract：:This study was conducted to quantify the association between meteorological variables and incidence of Plasmodium falciparum in areas with unstable malaria transmission in Ethiopia. We used morbidity data pertaining to microscopically confirmed cases reported from 35 sites throughout Ethiopia over a period of approxim...

journal_title：Parasitology

authors： Abeku TA,De Vlas SJ,Borsboom GJ,Tadege A,Gebreyesus Y,Gebreyohannes H,Alamirew D,Seifu A,Nagelkerke NJ,Habbema JD

更新日期：2004-06-01 00:00:00

abstract：:Distribution of Leptorhynchoides thecatus (Acanthocephala: Rhadinorhynchidae) among the pyloric caeca and the relationship between site and rate of maturation were studied in laboratory infections of 10, 25 and 40 cystacanths fed to green sunfish, Lepomis cyanellus. After 1 week fish fed at each intensity had signific...

journal_title：Parasitology

authors： Ewald JA,Nickol BB

更新日期：1989-06-01 00:00:00

abstract：:Murine monoclonal antibodies (mAbs) against Neospora caninum tachyzoites were produced to identify the cross-reactive antigens between N. caninum and Toxoplasma gondii. Ten mAbs recognizing cross-reactive antigens of both parasites were obtained and tentatively classified into 6 different groups based on their reactiv...

journal_title：Parasitology

authors： Liao M,Xuan X,Huang X,Shirafuji H,Fukumoto S,Hirata H,Suzuki H,Fujisaki K

更新日期：2005-05-01 00:00:00

abstract：:Accurately identifying resistance to gastrointestinal nematode infections requires the ability to identify animals with low and high intensities of infection. The pathogenic effects of nematodes depend upon both the length and number of worms, neither of which can be measured in live animals. Indices that predict thes...

journal_title：Parasitology

authors： Mair C,Matthews L,De Cisneros JP,Stefan T,Stear MJ

更新日期：2015-05-01 00:00:00

abstract：:Small RNAs are important regulators of gene expression. They were first identified in Caenorhabditis elegans, but it is now apparent that the main small RNA silencing pathways are functionally conserved across diverse organisms. Availability of genome data for an increasing number of parasitic nematodes has enabled bi...

journal_title：Parasitology

authors： Britton C,Laing R,Devaney E

更新日期：2020-07-01 00:00:00

abstract：:Classical and reverse genetics remain invaluable tools for the scientific investigation of model organisms. Genetic analysis of endoparasites is generally difficult because the sexual adults required for crossing and other manipulations are usually hidden within their host. Strongyloides spp. and Parastrongyloides spp...

journal_title：Parasitology

authors： Streit A

更新日期：2017-03-01 00:00:00

abstract：:The dynamic interaction of cells of the immune system with other cells, antigens and secreted factors determines the nature of an immune response. The response of individual cells is governed by the sequence of intracellular signalling events triggered following the association of cell surface molecules during cell-ce...

journal_title：Parasitology

authors： Goodridge HS,Harnett MM

更新日期：2005-01-01 00:00:00

abstract：:Intraerythrocytic malaria parasites ingest the cytosol of their host cell and digest it inside their acid food vacuoles. Acidified (pH 4-5.5, 37 degrees C) human red blood cell lysates were used to simulate this process, measuring the denaturation of haemoglobin (Hb) and the release of iron, in the absence or presence...

journal_title：Parasitology

authors： Gabay T,Krugliak M,Shalmiev G,Ginsburg H

更新日期：1994-05-01 00:00:00

abstract：:Macrogametogony and the formation of the oocyst wall has been examined in Eimeria acervulina. Macrogametes develop within a parasitophorous vacuole. Within the cytoplasm can be observed wall-forming bodies of Type I (WFBI) and Type II (WFBII), a nucleus, mitochondria, canaliculi and polysaccharide granules. WFBII are ...

journal_title：Parasitology

authors： Pittilo RM,Ball SJ

更新日期：1984-08-01 00:00:00

abstract：:We describe a laboratory model using Eimeria falciformis and E. pragensis to investigate some of the interactions in double-species infections of Eimeria. Mice were given trickle infections by oral inoculation of 100 sporulated oocysts of one species at 3 or 4 day intervals throughout the experiments and, once immunit...

journal_title：Parasitology

authors： Shehu K,Nowell F

更新日期：1998-11-01 00:00:00

abstract：:The complete small subunit ribosomal RNA (srRNA) gene of Theileria parva was cloned and sequenced. Two primers were designed which permitted the specific amplification of part of the Theileria srRNA gene from Theileria-infected cell line samples which were predominantly (> 95%) bovine DNA. The sequence of the central ...

journal_title：Parasitology

authors： Allsopp BA,Baylis HA,Allsopp MT,Cavalier-Smith T,Bishop RP,Carrington DM,Sohanpal B,Spooner P

更新日期：1993-08-01 00:00:00

abstract：:The phylogenetic relationship of 5 genera, i.e. Diplozoon Nordmann, 1832, Paradiplozoon Achmerov, 1974, Inustiatus Khotenovsky, 1978, Sindiplozoon Khotenovsky, 1981, and Eudiplozoon Khotenovsky, 1985 in the subfamily Diplozoinae Palombi, 1949 (Monogenea, Polyopisthocotylea) was inferred from rDNA ITS-2 region using ne...

journal_title：Parasitology

authors： Gao Q,X Chen M,Yao WJ,Gao Y,Song Y,Wang GT,Wang MX,Nie P

更新日期：2007-05-01 00:00:00

abstract：:The period 1875-1925 was remarkable in the history of parasitology mainly for the elucidation of the life cycles of parasites causing important parasitic diseases and the incrimination of vectors in their transmission. These discoveries were made by a small number of scientists working in the tropics a number of whom ...

journal_title：Parasitology

authors： Cox FEG

更新日期：2017-10-01 00:00:00

abstract：:We examined the mechanism of action and compared the anthelmintic efficacy of cysteine proteinases from papaya, pineapple, fig, kiwi fruit and Egyptian milkweed in vitro using the rodent gastrointestinal nematode Heligmosomoides polygyrus. Within a 2 h incubation period, all the cysteine proteinases, with the exceptio...

journal_title：Parasitology

authors： Stepek G,Buttle DJ,Duce IR,Lowe A,Behnke JM

更新日期：2005-02-01 00:00:00

abstract：:Neurocysticercosis (NCC) is the most common parasitic disease of the central nervous system (CNS) caused by the larval form of the tapeworm Taenia solium. NCC has a long asymptomatic period with little or no inflammation, and the sequential progression to symptomatic NCC depends upon the intense inflammation associate...

journal_title：Parasitology

authors： Alvarez JI,Mishra BB,Gundra UM,Mishra PK,Teale JM

更新日期：2010-03-01 00:00:00

abstract：:The presence of introduced hosts can increase or decrease infections of co-introduced parasites in native species of conservation concern. In this study, we compared parasite abundance, intensity, and prevalence between native Awaous stamineus and introduced poeciliid fishes by a co-introduced nematode parasite (Camal...

journal_title：Parasitology

authors： Gagne RB,Heins DC,McIntyre PB,Gilliam JF,Blum MJ

更新日期：2016-10-01 00:00:00

abstract：:In this review, we envisage the host environment, not as a hostile one, since the schistosome thrives there, but as one in which the relationship between the two organisms consists of constant communication, through signalling mechanisms involving sense organs, surface glycocalyx, surface membrane and internal organs ...

journal_title：Parasitology

authors： Kusel JR,Al-Adhami BH,Doenhoff MJ

更新日期：2007-10-01 00:00:00

abstract：:Taenia cestodes were obtained from 5 different definitive host species in Kenya and 175 different samples were examined by classical morphological methods and by isoenzyme analysis using isoelectric focusing in agarose. Gels were stained for 17 different enzymes and 3 of these were used in the construction of isoenzym...

journal_title：Parasitology

authors： Allsopp BA,Jones A,Allsopp MT,Newton SD,Macpherson CN

更新日期：1987-12-01 00:00:00

abstract：:The Baltic Sea is characterized by organisms that can tolerate brackish water. Because of the Sea's history during glacial times, its flora and fauna (and also their parasites) can be traced to marine, freshwater and genuine brackish elements beside glacial relics. Snails, planktonic copepods, benthic amphipods and is...

journal_title：Parasitology

authors： Zander CD,Reimer LW

更新日期：2002-01-01 00:00:00

abstract：:Dr David Livingstone died on May 1st 1873. He was 60 years old and had spent much of the previous 30 years walking across large stretches of Southern Africa, exploring the terrain he hoped could provide new environments in which Europeans and Africans could cohabit on equal terms and bring prosperity to a part of the ...

journal_title：Parasitology

authors： Barrett MP,Giordani F

更新日期：2017-10-01 00:00:00

abstract：:Two natural human interferon alpha preparations, (nHuIFN-alpha [Cantell]) and (nHuIFN-alpha [ISI]), were used for the oral treatment of cattle experimentally infected with Theileria parva parva. In the first experiment, 8 Friesian bulls were inoculated with a 1 in 10 dilution of a sporozoite stabilate of T.p. parva (M...

journal_title：Parasitology

authors： Young AS,Maritim AC,Kariuki DP,Stagg DA,Wafula JM,Mutugi JJ,Cummins JM,Richards AB,Burns C

更新日期：1990-10-01 00:00:00

abstract：:High throughput technologies continue to develop in response to the challenges set by the genome projects. This article discusses how the techniques of both high throughput screening (HTS) and synthesis can influence research in parasitology. Examples of the use of targeted and phenotype-based HTS using unbiased compo...

journal_title：Parasitology

authors： Morgan RE,Westwood NJ

更新日期：2004-01-01 00:00:00

abstract：:This study quantifies the rate and intensity of re-infection with human hookworm and Schistosoma mansoni infection 12 months following successful treatment, and investigates the influence of socio-economic, geographical and environmental factors. A longitudinal study of 642 individuals aged over 5 years was conducted ...

journal_title：Parasitology

authors： Cundill B,Alexander N,Bethony JM,Diemert D,Pullan RL,Brooker S

更新日期：2011-09-01 00:00:00