Abstract:
:Severe stenosis of the left main coronary artery (LMCA) generally occurs as a result of atherosclerosis and compromises the blood supply to a wide area of myocardium, thereby increasing the risk of serious adverse cardiac events. Current revascularization strategies for patients with significant LMCA disease include coronary artery bypass grafting (CABG) and percutaneous coronary intervention (PCI), both of which have a range of advantages and disadvantages. In general, PCI is associated with a lower rate of periprocedural adverse events and provides more rapid recovery, while CABG provides more durable revascularization. Most clinical trials comparing PCI and CABG for the treatment of LMCA disease have shown PCI to be non-inferior to CABG with respect to mortality and the serious composite outcome of death, myocardial infarction, or stroke in patients with low-to-intermediate anatomical complexities. Remarkable advancements in PCI standards, including safer and more effective stents, adjunctive intravascular imaging or physiologic evaluation, and antithrombotic treatment, may have contributed to these favorable results. This review provides an update on the current management of LMCA disease with an emphasis on clinical data and academic and clinical knowledge that supports the use of PCI in an increasing proportion of patients with LMCA disease.
journal_name
Korean Circ Jjournal_title
Korean circulation journalauthors
Cho SC,Park DW,Park SJdoi
10.4070/kcj.2019.0112subject
Has Abstractpub_date
2019-05-01 00:00:00pages
369-383issue
5eissn
1738-5520issn
1738-5555pii
49.369journal_volume
49pub_type
杂志文章,评审abstract:BACKGROUND AND OBJECTIVES:Bicaval heart transplantation (HTx) may promote parasympathetic reinnervation. However, the prevalence and timing of reinnervation have not been fully investigated. Heart rate variability (HRV) and direct vagal stimulation were used to evaluate the presence of parasympathetic reinnervation aft...
journal_title:Korean circulation journal
pub_type: 杂志文章
doi:10.4070/kcj.2016.46.2.197
更新日期:2016-03-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Transcatheter device closure becomes the first option for treating secundum atrial septal defect (ASD), but the conventional method is sometimes unsuccessful even when the defect size indicates the closure to be feasible. To increase the success rate, modified methods have been introduced and ...
journal_title:Korean circulation journal
pub_type: 杂志文章
doi:10.4070/kcj.2015.45.3.216
更新日期:2015-05-01 00:00:00
abstract::Behçet's disease (BD) is a multisystem vascular inflammatory disease. BD can affect blood vessels of nearly all sizes and types. Arterial involvement is a rare but serious condition in the course of BD. Here, we report a case of stenosis at the iliac artery bifurcation which was treated with percutaneous balloon angio...
journal_title:Korean circulation journal
pub_type: 杂志文章
doi:10.4070/kcj.2014.44.5.351
更新日期:2014-09-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Intermediate coronary lesion that can be under- or over-estimated by visual estimation frequently results in stenting of functionally nonsignificant lesions or deferral of percutaneous coronary intervention (PCI) of significant lesions inappropriately. We evaluated current status of PCI for in...
journal_title:Korean circulation journal
pub_type: 杂志文章
doi:10.4070/kcj.2019.0074
更新日期:2019-11-01 00:00:00
abstract::Non-valvular atrial fibrillation (AF) is the most common cardiac arrhythmia in the clinical setting. AF increases both the risk and severity of strokes, and is associated with substantial morbidity and mortality. Despite the clear net clinical benefit of oral anticoagulants (OACs) in patients with AF at risk for strok...
journal_title:Korean circulation journal
pub_type: 杂志文章,评审
doi:10.4070/kcj.2014.44.5.281
更新日期:2014-09-01 00:00:00
abstract::For over 3 decades, it has been known that reentry circuits for ventricular tachycardia (VT) are not limited to the subendocardial myocardium. Rather, intramural or subepicardial substrates may also give rise to VT, particularly in those with non-ischemic cardiomyopathy. Percutaneous epicardial mapping and ablation ha...
journal_title:Korean circulation journal
pub_type: 杂志文章,评审
doi:10.4070/kcj.2018.0210
更新日期:2018-09-01 00:00:00
abstract::Echocardiographic diagnosis of atrial myxoma may not always be straightforward, and the distinction between myxoma and thrombi is not easy, especially when we observe a mass after successful surgery. Our report describes a 72-year-old woman who presented with right upper limb hemiparesis and was subsequently diagnosed...
journal_title:Korean circulation journal
pub_type: 杂志文章
doi:10.4070/kcj.2016.46.6.875
更新日期:2016-11-01 00:00:00
abstract::An effective anticoagulation is critical in pregnant patients with prosthetic heart valves. Inherited disorders may interfere with the coagulation cascade and may be associated with obstetrical complications as well as with prosthetic valve-derived complications. The patient in the present case had a history of recurr...
journal_title:Korean circulation journal
pub_type: 杂志文章
doi:10.4070/kcj.2014.44.4.268
更新日期:2014-07-01 00:00:00
abstract::Congestive heart failure is a major cause of morbidity and mortality as well as a major health care cost in the developed world. Despite the introduction of highly effective heart failure medical therapies and simple devices such as cardiac resynchronization therapy that reduce mortality, improve cardiac function and ...
journal_title:Korean circulation journal
pub_type: 杂志文章,评审
doi:10.4070/kcj.2019.0161
更新日期:2019-07-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The objective was to compare the rate of onset of diabetes mellitus (DM) in patients with atrial fibrillation (AF) as compared with atrial flutter (AFL). METHODS:The incidence of DM through the national cohort registry in 14,014 newly diagnosed AF and 14,014 newly diagnosed AFL was investigat...
journal_title:Korean circulation journal
pub_type: 杂志文章
doi:10.4070/kcj.2019.0367
更新日期:2020-06-01 00:00:00
abstract::QT prolongation is a serious adverse drug effect, which is associated with an increased risk of Torsade de pointes and sudden death. Many drugs, including both cardiac and non-cardiac drugs, have been reported to cause prolongation of QT interval. Although meperidine has not been considered proarrhythmic, we present a...
journal_title:Korean circulation journal
pub_type: 杂志文章
doi:10.4070/kcj.2011.41.6.342
更新日期:2011-06-01 00:00:00
abstract::There have been great advances in ventricular assist device (VAD) treatment for pediatric patients with advanced heart failure. VAD support provides more time for the patient in the heart transplant waiting list. Augmented cardiac output improves heart failure symptoms, end-organ function, and general condition, and c...
journal_title:Korean circulation journal
pub_type: 杂志文章,评审
doi:10.4070/kcj.2019.0163
更新日期:2019-08-01 00:00:00
abstract::A 35-year-old Korean man with a 10-year history of ulcerative colitis (UC) presented with pain and swelling of the right neck. The patient was diagnosed with Takayasu's arteritis (TA) and had human leukocyte antigen (HLA) B-52, which is frequently found in patients having both UC and Takayasu's disease concurrently on...
journal_title:Korean circulation journal
pub_type: 杂志文章
doi:10.4070/kcj.2013.43.2.135
更新日期:2013-02-01 00:00:00
abstract::A 77-year-old female patient underwent aortic valve replacement (AVR) with concomitant septal myectomy and tricuspid annuloplasty. Her symptoms did not improve after a successful operation. Echocardiogram demonstrated the presence of an iatrogenic ventricular septal defect (VSD). It was muscular in location and not th...
journal_title:Korean circulation journal
pub_type: 杂志文章
doi:10.4070/kcj.2014.44.1.45
更新日期:2014-01-01 00:00:00
abstract::Without significant coronary artery stenosis, ischemic electrocardiographic change including ST segment elevation, segmental wall motion abnormality and elevated serum cardiac-specific markers (creatine kinase-MB, Troponin-T) may develop after central nervous system injuries such as subarachnoid, intracranial or subdu...
journal_title:Korean circulation journal
pub_type: 杂志文章
doi:10.4070/kcj.2012.42.3.216
更新日期:2012-03-01 00:00:00
abstract::Although its use in daily practice is not common, optical coherence tomography (OCT) is a powerful research tool in invasive cardiology. This report describes a hazy angiography image after percutaneous coronary intervention that has been assessed using OCT. Based on the results of the OCT, the patient underwent an el...
journal_title:Korean circulation journal
pub_type: 杂志文章
doi:10.4070/kcj.2013.43.1.44
更新日期:2013-01-01 00:00:00
abstract::A 34-year-old man, who had been treated with an endoscopic injection of a mixture of n-butyl-2-cyanoacrylate (Histoacryl) and Lipiodol for control of variceal bleeding 6 months previously, presented with an intracardiac mass in the right atrium (RA). Two-dimensional echocardiography revealed an intracardiac mass in th...
journal_title:Korean circulation journal
pub_type: 杂志文章
doi:10.4070/kcj.2010.40.9.468
更新日期:2010-09-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:There is a paucity of data regarding the benefit of clopidogrel monotherapy after dual antiplatelet therapy (DAPT) in patients treated with drug-eluting stents (DES). This study compared outcome between clopidogrel versus aspirin as monotherapy after DES for acute myocardial infarction (MI). ...
journal_title:Korean circulation journal
pub_type: 杂志文章
doi:10.4070/kcj.2019.0166
更新日期:2020-02-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Clinical data for Korean patients with bicuspid aortic valve (BAV) that underwent aortic valve (AV) surgery are currently limited. METHODS:Data for 1,160 consecutive adult BAV patients who underwent AV surgery from 2000 to 2014 in 4 tertiary referral centers were retrospectively analyzed. A s...
journal_title:Korean circulation journal
pub_type: 杂志文章
doi:10.4070/kcj.2017.0124
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Chronic impairment of β-adrenergic receptor signaling increases cardiac apoptosis, hypertrophy and fibrosis. The aim of this study was to investigate whether isoproterenol (ISO), an agonist of the adrenergic receptor, can enhance tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-...
journal_title:Korean circulation journal
pub_type: 杂志文章
doi:10.4070/kcj.2016.46.1.93
更新日期:2016-01-01 00:00:00
abstract::In the absence of hypertension, hypertrophic cardiomyopathy is the most common cause of left ventricular hypertrophy (LVH). However, it has been reported that up to 3% of males with unexplained LVH have Fabry disease, an X-linked disorder of glycophospholipid metabolism that is due to a deficiency in the lysosomal enz...
journal_title:Korean circulation journal
pub_type: 杂志文章
doi:10.4070/kcj.2009.39.8.335
更新日期:2009-08-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:High waist circumference (WC) is associated with increased cardiovascular risk (CVR) in adulthood. We investigated this association in adolescents. METHODS:We performed a cross-sectional analysis of data for 10-18-year-olds included in the Korea National Health and Nutrition Examination Surve...
journal_title:Korean circulation journal
pub_type: 杂志文章
doi:10.4070/kcj.2019.0329
更新日期:2020-08-01 00:00:00
abstract::Platelet aggregation is not only an essential part of hemostasis, but also initiates acute coronary syndrome or ischemic stroke. The precise understanding of the activation mechanism of platelet aggregation is fundamental for the development of more effective agents against platelet aggregation. Adenosine diphosphate,...
journal_title:Korean circulation journal
pub_type: 杂志文章
doi:10.4070/kcj.2012.42.5.295
更新日期:2012-05-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The drug-eluting balloon (DEB) catheter system was developed to treat restenosis. Furthermore, DEB angioplasty has been shown to reduce restenosis risk when compared to drug-eluting stents (DES) in patients with in-stent restenosis (ISR) or small vessel disease (SVD). In addition, DEB angiopla...
journal_title:Korean circulation journal
pub_type: 杂志文章
doi:10.4070/kcj.2011.41.12.705
更新日期:2011-12-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The prognosis and natural history of bradycardia related to drugs such as beta-blockers and non-dihydropyridine calcium channel blockers are not well known. SUBJECTS AND METHODS:We retrospectively analyzed 38 consecutive patients (age 69+/-11, 21 women) with drug-related bradycardia (DRB) bet...
journal_title:Korean circulation journal
pub_type: 杂志文章
doi:10.4070/kcj.2009.39.9.367
更新日期:2009-09-01 00:00:00
abstract::Coronary artery anomalies are rare presentations in primary percutaneous coronary interventions of acute myocardial infarction. Herein, we report the case of a 59-year-old man with acute anterior myocardial infarction who had anomalous separate origin of left anterior descending artery (LAD) and left circumflex artery...
journal_title:Korean circulation journal
pub_type: 杂志文章
doi:10.4070/kcj.2013.43.6.408
更新日期:2013-06-01 00:00:00
abstract::Atrial fibrillation (AF) is the most common arrhythmia and is associated with increased cardiovascular morbidity and mortality. The anti-arrhythmic effect of statins on AF prevention appears to be highly significant in most clinical studies. However, some discrepancies do exist among different clinical studies. Differ...
journal_title:Korean circulation journal
pub_type: 杂志文章,评审
doi:10.4070/kcj.2014.44.4.205
更新日期:2014-07-01 00:00:00
abstract::The incidence of peri-stent graft infection (PGI) following thoracic endovascular aortic repair (TEVAR) is low, but the associated mortality rates are extremely high. The diagnosis of this complication can be difficult due to nonspecific symptoms. Here, we report a case of PGI combined with an aorto-esophageal fistula...
journal_title:Korean circulation journal
pub_type: 杂志文章
doi:10.4070/kcj.2012.42.5.366
更新日期:2012-05-01 00:00:00
abstract::A 40-year-old male patient underwent radiofrequency catheter ablation for symptomatic paroxysmal atrial fibrillation (AF). Although pulmonary vein (PV) isolation was successfully completed without acute complications, the patient began complaining of sustained retrosternal pain. Seventeen days after ablation, the pati...
journal_title:Korean circulation journal
pub_type:
doi:10.4070/kcj.2016.0364
更新日期:2017-11-01 00:00:00
abstract::Herein, we present a case of a successful catheter ablation of ventricular tachycardia (VT) using a radial artery approach in a post-myocardial infarction patient, who had an implantable cardioverter-defibrillator and peripheral artery disease. Although the patient did not use antiarrhythmic drugs, the patient experie...
journal_title:Korean circulation journal
pub_type: 杂志文章
doi:10.4070/kcj.2012.42.9.632
更新日期:2012-09-01 00:00:00