Temperate Prophages Increase Bacterial Adhesin Expression and Virulence in an Experimental Model of Endocarditis Due to Staphylococcus aureus From the CC398 Lineage.

abstract：:Due to the high incidence of nosocomial Candida albicans infection, the first-line drugs for C. albicans infection have been heavily used, and the emergence of drug-resistant strains has gradually increased. Thus, a new antifungal drug or therapeutic method is needed. Chitosan, a product of chitin deacetylation, is co...

journal_title：Frontiers in microbiology

authors： Shih PY,Liao YT,Tseng YK,Deng FS,Lin CH

更新日期：2019-03-26 00:00:00

abstract：:Clostridioides difficile is the leading cause of worldwide antibiotics-associated diarrhea. In this study, we report the construction and evaluation of a novel bacteriophage lysin-human defensin fusion protein targeting C. difficile. The fusion protein, designated LHD, is composed of two parts connected by a 3-repeati...

journal_title：Frontiers in microbiology

authors： Peng Z,Wang S,Gide M,Zhu D,Lamabadu Warnakulasuriya Patabendige HM,Li C,Cai J,Sun X

更新日期：2019-01-11 00:00:00

abstract：Background:Antimicrobial resistance (AMR) thwarts the curative power of drugs and is a present-time global problem. We present data on antimicrobial susceptibility and resistance determinants of bacteria the WHO has highlighted as being key antimicrobial resistance concerns in Africa, to strengthen knowledge of AMR pat...

journal_title：Frontiers in microbiology

authors： Moirongo RM,Lorenz E,Ntinginya NE,Dekker D,Fernandes J,Held J,Lamshöft M,Schaumburg F,Mangu C,Sudi L,Sie A,Souares A,Heinrich N,Wieser A,Mordmüller B,Owusu-Dabo E,Adegnika AA,Coulibaly B,May J,Eibach D

更新日期：2020-09-25 00:00:00

abstract：:Anaerobic dechlorination of chlorophenols often subjects to their toxicity and recalcitrance, presenting low loading rate and poor degradation efficiency. In this study, in order to accelerate p-chlorophenol (p-CP) reduction and extracellular electron transfer in an anaerobic system, three iron-oxide nanoparticles, na...

journal_title：Frontiers in microbiology

authors： Jiang X,Chen Y,Hou C,Liu X,Ou C,Han W,Sun X,Li J,Wang L,Shen J

更新日期：2018-08-30 00:00:00

abstract：:Increasing the final titer of a multi-gene metabolic pathway can be viewed as a multivariate optimization problem. While numerous multivariate optimization algorithms exist, few are specifically designed to accommodate the constraints posed by genetic engineering workflows. We present a strategy for optimizing express...

journal_title：Frontiers in microbiology

authors： Heinsch SC,Das SR,Smanski MJ

更新日期：2018-02-27 00:00:00

abstract：:In this study, compound microbial inoculants, including three Bacillus strains and one Yeast strain, were inoculated into swine manure composting to explore the effects on antibiotic resistance genes (ARGs) and mobile genetic elements (MGEs), microbial community structure, and pathogenic bacteria. The results indicate...

journal_title：Frontiers in microbiology

authors： Li K,Cao R,Mo S,Yao R,Ren Z,Wu J

更新日期：2020-11-03 00:00:00

abstract：:The pathogenicity of Stenotrophomonas maltophilia is regulated in part by its quorum sensing (QS) system. The main QS signaling molecule in S. maltophilia is known as diffusible signal factor (DSF), and the rpf gene cluster is responsible for its synthesis and perception. Two cluster variants have been previously desc...

journal_title：Frontiers in microbiology

authors： Yero D,Huedo P,Conchillo-Solé O,Martínez-Servat S,Mamat U,Coves X,Llanas F,Roca I,Vila J,Schaible UE,Daura X,Gibert I

更新日期：2020-06-03 00:00:00

abstract：:A growing body of clinical and experimental data supports the view that the efficacy of probiotics is strain-specific and restricted to particular pathological conditions, which means that newly isolated probiotic strains need to be targeted to a specific disease. Following national and international guidelines, we us...

journal_title：Frontiers in microbiology

authors： Sagheddu V,Uggeri F,Belogi L,Remollino L,Brun P,Bernabè G,Moretti G,Porzionato A,Morelli L,Castagliuolo I,Elli M

更新日期：2020-04-15 00:00:00

abstract：:Internal bacterial concentration of Mg2+, the most abundant divalent cation in living cells, is estimated to be in the single millimolar range. However, many bacteria will thrive in media with only micromolars of Mg2+, by using a range of intensely studied and highly efficient import mechanisms, as well as in media wi...

journal_title：Frontiers in microbiology

authors： Armitano J,Redder P,Guimarães VA,Linder P

更新日期：2016-11-25 00:00:00

abstract：:The extensive use of acids in a variety of manufacturing industries results in the increase of discharged acidic waste stream into the environment. Such co-pollution of acids and other organic pollutants limits the biodegradation capability of neutrophilic degraders. With high-throughput genetic techniques, we aim to ...

journal_title：Frontiers in microbiology

authors： Zhou Z,Liu Y,Zanaroli G,Wang Z,Xu P,Tang H

更新日期：2019-09-04 00:00:00

abstract：:Clostridium difficile infection (CDI) is a major cause of infectious diarrhea among hospitalized patients. Probiotics could be instrumental in restoring the intestinal dysbiosis caused by CDI. Here, we examined the protective effect of Pediococcus pentosaceus LI05 in a mouse CDI model. C57BL/6 mice were administrated ...

journal_title：Frontiers in microbiology

authors： Xu Q,Gu S,Chen Y,Quan J,Lv L,Chen D,Zheng B,Xu L,Li L

更新日期：2018-10-09 00:00:00

abstract：:Candida albicans can form biofilms composed of yeast, hyphal, and pseudohyphal elements, and C. albicans cells in the hyphal stage could be a virulence factor. The present study describes the chemical composition, antibiofilm, and antihyphal activities of cedar leaf essential oil (CLEO), which was found to possess rem...

journal_title：Frontiers in microbiology

authors： Manoharan RK,Lee JH,Lee J

更新日期：2017-08-03 00:00:00

abstract：:Twenty-three Saccharomyces cerevisiae strains isolated from different fermented foods of Western Himalayas have been studied for strain level and functional diversity in our department. Among these 23 strains, 10 S. cerevisiae strains on the basis of variation in their brewing traits were selected to study their organ...

journal_title：Frontiers in microbiology

authors： Kanwar SS,Keshani

更新日期：2016-06-28 00:00:00

abstract：:Interactions with microbes affect many aspects of animal biology, including immune system development, nutrition and health. In vertebrates, the gut microbiota is dominated by a small subset of phyla, but the species composition within these phyla is typically not conserved. Moreover, several recent studies have shown...

journal_title：Frontiers in microbiology

authors： Ellegaard KM,Engel P

更新日期：2016-09-21 00:00:00

abstract：:Toxoplasma gondii is the causative agent for toxoplasmosis. The rhoptry protein 1 (ROP1) is secreted by rhoptry, an apical secretory organelle of the parasite. ROP1 plays an important role in host cell invasion. In this study, the efficacy of ROP1 as a vaccine candidate against toxoplasmosis was evaluated through intr...

journal_title：Frontiers in microbiology

authors： Sonaimuthu P,Ching XT,Fong MY,Kalyanasundaram R,Lau YL

更新日期：2016-05-27 00:00:00

abstract：:Whole genome sequencing (WGS) of Mycobacterium tuberculosis has been constructive in understanding its evolution, genetic diversity and the mechanisms involved in drug resistance. A large number of sequencing efforts from across the globe have revealed genetic diversity among clinical isolates and the genetic determin...

journal_title：Frontiers in microbiology

authors： Advani J,Verma R,Chatterjee O,Pachouri PK,Upadhyay P,Singh R,Yadav J,Naaz F,Ravikumar R,Buggi S,Suar M,Gupta UD,Pandey A,Chauhan DS,Tripathy SP,Gowda H,Prasad TSK

更新日期：2019-02-26 00:00:00

abstract：:Toxoplasma gondii rhoptry proteins (TgROPs) are the major targets as key molecules for immunodiagnosis as well as immunoprophylaxis because of their initial presentation to the host immune system. In this work, it was aimed at evaluating the protection effect of TgROP21 DNA vaccine on experimental mice subjected to T....

journal_title：Frontiers in microbiology

authors： Zhang Z,Li Y,Wang M,Xie Q,Li P,Zuo S,Kong L,Wang C,Wang S

更新日期：2018-05-08 00:00:00

abstract：:In the present study, long-term organic and conventional managements were compared at the experimental field of Monsampolo del Tronto (Marche region, Italy) with the aim of investigating soil chemical fertility and microbial community structure. A polyphasic approach, combining soil fertility indicators with microbiol...

journal_title：Frontiers in microbiology

authors： Stagnari F,Perpetuini G,Tofalo R,Campanelli G,Leteo F,Della Vella U,Schirone M,Suzzi G,Pisante M

更新日期：2014-12-10 00:00:00

abstract：:The amendment of crop residues produced under elevated CO2 (eCO2) may alter soil microbial community structure and their functions on residue decomposition and carbon (C) cycling in soil. The key to understanding this process is to elucidate the structure of prokaryotic communities that metabolize crop residues derive...

journal_title：Frontiers in microbiology

authors： Wang Y,Yu Z,Li Y,Wang G,Tang C,Liu X,Liu J,Xie Z,Jin J

更新日期：2019-09-24 00:00:00

abstract：:Phylogenetically deeply rooted methanogens belonging to the genus of Methanocaldococcus living in deep-sea hydrothermal vents derive energy exclusively from hydrogenotrophic methanogenesis, one of the oldest respiratory metabolisms on Earth. These hyperthermophilic, autotrophic archaea synthesize their biomolecules fr...

journal_title：Frontiers in microbiology

authors： Susanti D,Frazier MC,Mukhopadhyay B

更新日期：2019-07-03 00:00:00

abstract：:Two-component regulatory systems (TCSSs) are key regulatory elements responsible for the adaptation of bacteria to environmental stresses. A classical TCSS is typically comprised of a sensory histidine kinase and a corresponding response regulator. Here, we used homologous recombination to construct a Mycobacterium sm...

journal_title：Frontiers in microbiology

authors： Dadura K,Płocińska R,Rumijowska-Galewicz A,Płociński P,Żaczek A,Dziadek B,Zaborowski A,Dziadek J

更新日期：2017-11-03 00:00:00

abstract：:Enterohemorrhagic Escherichia coli O157:H7 (EHEC O157:H7) causes hemorrhagic colitis and the formation of characteristic attaching and effacing (A/E) lesions in humans. Given the severe sequelae of EHEC O157:H7 infection, it is critical to develop effective vaccines for human use. However, for achieving this goal many...

journal_title：Frontiers in microbiology

authors： Lin R,Zhang Y,Long B,Li Y,Wu Y,Duan S,Zhu B,Wu X,Fan H

更新日期：2017-03-15 00:00:00

abstract：:The process of transformation of table olives from tree to table is the result of complex biochemical reactions that are determined by the interactions between the indigenous microflora of the olives, together with a variety of contaminating microrganisms from different sources [fiber-glass fermenters, polyvinyl chlor...

journal_title：Frontiers in microbiology

authors： Lanza B

更新日期：2013-05-10 00:00:00

abstract：:The viruses play an important role in limiting bacterial abundance in oceans and, hence, in regulating bacterial biogeochemical functions. A cruise was conducted in September 2005 along a transect in the deep South China Sea (SCS). The results showed the double maxima in the ratio of viral to bacterial abundance (VBR)...

journal_title：Frontiers in microbiology

authors： He L,Yin K,Yuan X

更新日期：2019-07-16 00:00:00

abstract：:In this study we investigated how the source of organic carbon (Corg) and nitrogen (Norg) affects the interactions between fungi of the genus Morchella and bacteria dispersing along their hyphae (fungal highways; FH). We demonstrated that bacteria using FH increase the hydrolysis of an organic nitrogen source that onl...

journal_title：Frontiers in microbiology

authors： Lohberger A,Spangenberg JE,Ventura Y,Bindschedler S,Verrecchia EP,Bshary R,Junier P

更新日期：2019-03-01 00:00:00

abstract：:Controlling aflatoxigenic Aspergillus flavus and aflatoxins (AFs) in grains and food during storage is a great challenge to humans worldwide. Alcaligenes faecalis N1-4 isolated from tea rhizosphere soil can produce abundant antifungal volatiles, and greatly inhibited the growth of A. flavus in un-contacted face-to-fac...

journal_title：Frontiers in microbiology

authors： Gong AD,Wu NN,Kong XW,Zhang YM,Hu MJ,Gong SJ,Dong FY,Wang JH,Zhao ZY,Liao YC

更新日期：2019-06-25 00:00:00

abstract：:Bacteriocins are proteinaceous antibacterial compounds, produced by diverse bacteria, which have been successfully used as: (i) food biopreservative; (ii) anti-biofilm agents; and (iii) additives or alternatives to the currently existing antibiotics, to minimize the risk of emergence of resistant strains. However, the...

journal_title：Frontiers in microbiology

authors： Fahim HA,Khairalla AS,El-Gendy AO

更新日期：2016-09-16 00:00:00

abstract：:Storm events impact freshwater microbial communities by transporting terrestrial viruses and other microbes to freshwater systems, and by potentially resuspending microbes from bottom sediments. The magnitude of these impacts on freshwater ecosystems is unknown and largely unexplored. Field studies carried out at two ...

journal_title：Frontiers in microbiology

authors： Williamson KE,Harris JV,Green JC,Rahman F,Chambers RM

更新日期：2014-03-14 00:00:00

abstract：:Candida species can cause severe infections associated with high morbidity and mortality. Therefore, it is essential to gain more insight into the anti-fungal host defense response. The advent of omics technology and development of advanced systems biology tools has permitted to approach this in an unbiased and quanti...

journal_title：Frontiers in microbiology

authors： Smeekens SP,van de Veerdonk FL,Netea MG

更新日期：2016-02-16 00:00:00

abstract：:Pseudomonas syringae pv. tomato DC3000 carries the wssABCDEFGHI operon for the synthesis of acetylated cellulose, whose production is stimulated by increasing the intracellular levels of the second messenger c-di-GMP. This enhances air-liquid biofilm formation and generates a wrinkly colony morphotype in solid media. ...

journal_title：Frontiers in microbiology

authors： Pérez-Mendoza D,Felipe A,Ferreiro MD,Sanjuán J,Gallegos MT

更新日期：2019-04-17 00:00:00