MANAGEMENT OF ENDOCRINE DISEASE: Predictive scores in autoimmune thyroid disease: are they useful?

abstract：OBJECTIVE:A sex difference in fetal and neonatal pituitary-gonadal function has been well documented. The aim of the following study was to determine sex differences and patterns of basal LH/FSH in the neonatal period. DESIGN:Peripheral venous blood was obtained from 164 healthy full term newborns (91 males, 73 female...

journal_title：European journal of endocrinology

authors： Schmidt H,Schwarz HP

更新日期：2000-08-01 00:00:00

abstract：OBJECTIVE:Limited data exist concerning the presence of polycystic ovary syndrome (PCOS) in premenopausal women with nonalcoholic fatty liver disease (NAFLD). We aimed to investigate the prevalence of PCOS in overweight and obese premenopausal women with NAFLD. DESIGN:Prospective, observational, and cross-sectional st...

journal_title：European journal of endocrinology

authors： Vassilatou E,Vassiliadi DA,Salambasis K,Lazaridou H,Koutsomitopoulos N,Kelekis N,Kassanos D,Hadjidakis D,Dimitriadis G

更新日期：2015-12-01 00:00:00

abstract：:Recombinant human GH has been licensed for use in adult patients with GH deficiency (GHD) for over 15 years. Early weight- and surface area-based dosing regimens were effective but resulted in supraphysiological levels of IGF1 and increased incidence of side effects. Current practice has moved towards individualised r...

journal_title：European journal of endocrinology

authors： Gasco V,Prodam F,Grottoli S,Marzullo P,Longobardi S,Ghigo E,Aimaretti G

更新日期：2013-02-20 00:00:00

abstract：OBJECTIVE:Vitamin D insufficiency is common in primary hyperparathyroidism (pHPT). Patients with pHPT frequently have a reduced health-related quality of life (HRQoL). Our objectives were to evaluate whether HRQoL in pHPT is associated with vitamin D insufficiency and whether vitamin D supplementation after parathyroid...

journal_title：European journal of endocrinology

authors： Åberg V,Norenstedt S,Zedenius J,Sääf M,Nordenström J,Pernow Y,Nilsson IL

更新日期：2015-02-01 00:00:00

abstract：Objective:Retrospective studies suggest that women have more active brown adipose tissue (BAT) than men, but little is known of the effect of fluctuating sex steroids across the menstrual cycle on thermogenesis in women. Design:To characterise the effects of sex and sex steroids on BAT activity we recruited healthy we...

journal_title：European journal of endocrinology

authors： Fuller-Jackson JP,Dordevic AL,Clarke IJ,Henry BA

更新日期：2020-09-01 00:00:00

abstract：:Several bone matrix protein constituents, including the major component collagen type I and the hydroxyapatite binding protein, osteocalcin, have been implicated in the regulation of bone turnover. Cortical bone osteocalcin, collagen and mineral content were studied in autosomal dominant osteopetrosis type I (ADO), a ...

journal_title：European journal of endocrinology

authors： Bollerslev J,Marks SC Jr,Mosekilde L,Lian JB,Stein GS,Mosekilde L

更新日期：1994-06-01 00:00:00

abstract：OBJECTIVE:Though transsphenoidal surgery remains the first-line treatment of Cushing's disease, recurrence occurs frequently. Conventional radiotherapy and anticortisolic drugs both have adverse effects. Stereotactic radiosurgery needs to be evaluated more precisely. The aim of this study was to determine long-term hor...

journal_title：European journal of endocrinology

authors： Castinetti F,Nagai M,Dufour H,Kuhn JM,Morange I,Jaquet P,Conte-Devolx B,Regis J,Brue T

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVE:In order to characterize urinary gonadotropin peptide (UGP) as an acute phase reactant, we focused on the UGP levels after surgical operation. DESIGN:Fifty cases of gastrointestinal cancer, 4 cases of cancers of other organs and 13 cases of benign digestive diseases were enrolled into this study. METHODS:UG...

journal_title：European journal of endocrinology

authors： Motoo Y,Watanabe H,Okai T,Sawabu N

更新日期：1999-06-01 00:00:00

abstract：:For many years, it has been well documented that combined hormonal contraceptives increase the risk of venous thromboembolism (VTE). The third-generation pill use (desogestrel or gestodene (GSD)) is associated with an increased VTE risk as compared with second-generation (levonorgestrel) pill use. Other progestins suc...

journal_title：European journal of endocrinology

authors： Hugon-Rodin J,Gompel A,Plu-Bureau G

更新日期：2014-12-01 00:00:00

abstract：OBJECTIVE:Anti-inflammatory glucocorticoid (GC) therapy often induces hyperglycemia due to insulin resistance and islet-cell dysfunction. Incretin-based therapies may preserve glucose tolerance and pancreatic islet-cell function. In this study, we hypothesized that concomitant administration of the dipeptidyl peptidase...

journal_title：European journal of endocrinology

authors： van Genugten RE,van Raalte DH,Muskiet MH,Heymans MW,Pouwels PJ,Ouwens DM,Mari A,Diamant M

更新日期：2014-02-04 00:00:00

abstract：OBJECTIVE:To determine if human growth hormone (hGH) replacement therapy alters pharmacokinetics of hydrocortisone (CS) substitution in hypopituitary adults. DESIGN:To this aim, we analysed serum and salivary CS profiles 270 min after oral CS administration at baseline and 6 and 12 months after initiation of hGH repla...

journal_title：European journal of endocrinology

authors： Tschöp M,Lahner H,Feldmeier H,Grasberger H,Morrison KM,Janssen OE,Attanasio AF,Strasburger CJ

更新日期：2000-12-01 00:00:00

abstract：AIM:To characterize the clinical phenotype of type 2 diabetes mellitus (T2DM) with respect to age, gender, and BMI. METHOD:Anonymized data of 120,183 people with T2DM from the German/Austrian multicenter Diabetes Patienten Verlaufsdokumentation database were analyzed based on chronological age or age at diagnosis (0-1...

journal_title：European journal of endocrinology

authors： Awa WL,Fach E,Krakow D,Welp R,Kunder J,Voll A,Zeyfang A,Wagner C,Schütt M,Boehm B,de Souza M,Holl RW,DPV Initiative.,German BMBF Competence Networks Diabetes mellitus and Obesity.

更新日期：2012-08-01 00:00:00

abstract：OBJECTIVE:To investigate the association between birth weight and risk of type 2 diabetes, abdominal obesity and hypertension among Chinese adults. RESEARCH METHODS AND PROCEDURES:Nine hundred and seventy-three individuals from a population-based cross-sectional survey for the prevalence of type 2 diabetes conducted i...

journal_title：European journal of endocrinology

authors： Tian JY,Cheng Q,Song XM,Li G,Jiang GX,Gu YY,Luo M

更新日期：2006-10-01 00:00:00

abstract：OBJECTIVES:Evidence of the association between vitamin D and cardiovascular risk factors in the young is limited. We therefore assessed the relationships between circulating 25-hydroxyvitamin D(3) (25(OH)D(3)) and metabolic syndrome (MetS), its components, and early atherosclerotic changes in 452 (304 overweight/obese ...

journal_title：European journal of endocrinology

authors： Pacifico L,Anania C,Osborn JF,Ferraro F,Bonci E,Olivero E,Chiesa C

更新日期：2011-10-01 00:00:00

abstract：OBJECTIVE:Prolactin is capable of both trophic and lytic actions in rat corpora lutea. In corpora lutea responding to a trophic prolactin signal, the long form of the prolactin receptor is the dominant form and is upregulated by prolactin. We investigated whether mRNA for the short form of the prolactin receptor was do...

journal_title：European journal of endocrinology

authors： Bowen JM,Telleria CM,Towns R,Keyes PL

更新日期：2000-08-01 00:00:00

abstract：OBJECTIVE:The treatment of children with subclinical hypothyroidism (SH) is controversial for TSH values between 4.5 and 10 mU/l. The aim of this cross-sectional, controlled study was to evaluate growth and intellectual outcome in children with persistent SH who have never been treated with levothyroxine. DESIGN AND M...

journal_title：European journal of endocrinology

authors： Cerbone M,Bravaccio C,Capalbo D,Polizzi M,Wasniewska M,Cioffi D,Improda N,Valenzise M,Bruzzese D,De Luca F,Salerno M

更新日期：2011-04-01 00:00:00

abstract：:Deflazacort is an oxazoline derivative of cortisone with presumably less serious side effects, but its effects on growth factors are unknown. The present experiments in Long Evans rats were carried out to investigate how deflazacort administration affected the growing rat, especially in relation to hepatic insulin-lik...

journal_title：European journal of endocrinology

authors： Latta K,Krieg RJ Jr,Chan W,Hisano S,Chan JC

更新日期：1994-12-01 00:00:00

abstract：Objective:Fetal exposure to gestational diabetes mellitus (GDM) increases the risk of metabolic diseases in the offspring. Leptin, adiponectin, and fibroblast growth factor 21 (FGF21) may play potential roles in the underlying disease mechanisms. We investigated the impact of fetal exposure to GDM on leptin, adiponecti...

journal_title：European journal of endocrinology

authors： Kampmann FB,Thuesen ACB,Hjort L,Bjerregaard AA,Chavarro JE,Frystyk J,Bjerre M,Tetens I,Olsen SF,Vaag AA,Damm P,Grunnet LG

更新日期：2019-12-01 00:00:00

abstract：OBJECTIVE:Affective alterations and poorer quality of life often persist in patients with Cushing's syndrome (CS) in remission. Brain-derived neurotrophic factor (BDNF) regulates the hypothalamic-pituitary-adrenal axis (HPA) and is highly expressed in brain areas controlling mood and response to stress. Our aims were t...

journal_title：European journal of endocrinology

authors： Valassi E,Crespo I,Keevil BG,Aulinas A,Urgell E,Santos A,Trainer PJ,Webb SM

更新日期：2017-02-01 00:00:00

abstract：:Pyridostigmine (PST), a cholinesterase inhibitor, induces a clear growth hormone (GH) release in man by suppression of hypothalamic somatostatin (SRIH). Somatostatin suppresses thyrotrophin (TSH) release in rats and men. Earlier studies showed that the thryotrophin-releasing hormone (TRH)-induced TSH response was not ...

journal_title：European journal of endocrinology

authors： Yang I,Woo J,Kim S,Kim J,Kim Y,Choi Y

更新日期：1995-10-01 00:00:00

abstract：OBJECTIVE:Although the beneficial effects of estrogen on bone are well known, the roles of estrogen receptors (ERs) in mediating these effects are not fully understood. METHODS:To study the effects of long-term ER alpha deficiency, bone phenotype was studied in aged ER alpha knockout (ERKO) mice. In addition, ERKO ost...

journal_title：European journal of endocrinology

authors： Parikka V,Peng Z,Hentunen T,Risteli J,Elo T,Väänänen HK,Härkönen P

更新日期：2005-02-01 00:00:00

abstract：INTRODUCTION:Patients with craniopharyngioma (CP) have disturbances of the hypothalamic-pituitary axis and serious comorbidities such as obesity. We hypothesized that the secretion of hormones regulating the nutritional status is altered in adult patients with CP compared with patients with non-functioning pituitary ad...

journal_title：European journal of endocrinology

authors： Roemmler-Zehrer J,Geigenberger V,Störmann S,Losa M,Crippa V,Otto B,Bidlingmaier M,Dimopoulou C,Stalla GK,Schopohl J

更新日期：2014-03-13 00:00:00

abstract：OBJECTIVE:Muscle mass plays an important role in determining cardiovascular and metabolic risks in polycystic ovary syndrome (PCOS). In addition, whether lean mass influences carotid intima-media thickness (IMT) in PCOS has not been assessed. DESIGN:Prospective investigation. METHODS:Ninety-five women with PCOS were ...

journal_title：European journal of endocrinology

authors： Carmina E,Guastella E,Longo RA,Rini GB,Lobo RA

更新日期：2009-10-01 00:00:00

abstract：OBJECTIVES:We aimed to investigate the relationship between nonalcoholic fatty liver disease (NAFLD), serum adiponectin concentration and brachial-ankle pulse wave velocity (baPWV) as a risk marker for atherosclerosis. METHODS:A total of 213 nonalcoholic subjects (67 males, 146 females) participated in this study. Div...

journal_title：European journal of endocrinology

authors： Kim SG,Kim HY,Seo JA,Lee KW,Oh JH,Kim NH,Choi KM,Baik SH,Choi DS

更新日期：2005-02-01 00:00:00

abstract：OBJECTIVE:Activin is a growth and differentiation factor of many cell types, and has recently been implicated in inflammatory processes. Clinical data linking activin and its binding protein, follistatin (FS), are lacking. We measured serum levels of activin and FS in patients diagnosed with septicemia. PATIENTS AND M...

journal_title：European journal of endocrinology

authors： Michel U,Ebert S,Phillips D,Nau R

更新日期：2003-05-01 00:00:00

abstract：OBJECTIVE:Circulating IGF1 declines with age while ill-health increases. Controversy remains whether differences in the levels of IGF1 and its binding proteins 1 and 3 (IGFBP1 and IGFBP3) determine health outcomes during ageing. We examined associations of IGF1, IGFBP1 and IGFBP3 with all-cause and cardiovascular morta...

journal_title：European journal of endocrinology

authors： Yeap BB,Chubb SA,McCaul KA,Ho KK,Hankey GJ,Norman PE,Flicker L

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:The aim was to evaluate changes of bone mineral density (BMD) and markers of bone turnover in healthy adolescents, and in adolescent users of combined oral contraceptives (COCs) with different ethinylestradiol (EE) contents. METHODS:In this prospective crossover study, 56 healthy females (15-19.5 years) wit...

journal_title：European journal of endocrinology

authors： Cibula D,Skrenkova J,Hill M,Stepan JJ

更新日期：2012-06-01 00:00:00

abstract：:Phaeochromocytoma is a rare, usually benign, tumour predominantly managed by endocrinologists. Over the last decade, major advances have been made in understanding the molecular genetic basis of adrenal and extra-adrenal phaeochromocytoma (also referred to as adrenal phaeochromocytoma (aPCA) and extra-adrenal function...

journal_title：European journal of endocrinology

authors： Jafri M,Maher ER

更新日期：2012-02-01 00:00:00

abstract：:Patients with adrenal insufficiency need lifelong glucocorticoid replacement, but many suffer from poor quality of life, and overall there is increased mortality. Moreover, it appears that use of glucocorticoids at the higher end of the replacement dose range is associated with increased risk for cardiovascular and me...

journal_title：European journal of endocrinology

authors： Debono M,Ross RJ,Newell-Price J

更新日期：2009-05-01 00:00:00

abstract：:Growth hormone (GH) is used by athletes like bodybuilders to increase muscle strength and weight gain. On the other hand, chronic hypersecretion of GH in active acromegaly may result in outwardly hypertrophied but functionally weaker muscles. As a model for studying long-term effects of GH on muscle strength, we analy...

journal_title：European journal of endocrinology

authors： Wolf E,Wanke R,Schenck E,Hermanns W,Brem G

更新日期：1995-12-01 00:00:00