Decreased uric acid levels in the acute phase of Plasmodium vivax malaria.

Abstract:

INTRODUCTION:Uric acid is one of the compounds associated with the inflammatory process in malaria. It acts as an indicator of cellular damage by activating the immune response and inflammatory process. METHODS:We measured serum concentrations of uric acid in 60 symptomatic patients before and after treatment for malarial infections caused by Plasmodium vivax. RESULTS:Lower serum concentrations of uric acid were found during the acute phase of P. vivax malaria compared to those in its convalescent phase (p < 0.0001). CONCLUSIONS:Patients in the acute phase of malaria had lower uric acid levels than those in its convalescent phase.

journal_name

Rev Soc Bras Med Trop

authors

Gomes LT,Bellei AK,Andrade DI,Gotardo PZ,Nery AF,Fontes CJF

doi

10.1590/0037-8682-0412-2017

subject

Has Abstract

pub_date

2019-05-16 00:00:00

pages

e20170412

eissn

0037-8682

issn

1678-9849

pii

S0037-86822019000100649

journal_volume

52

pub_type

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