当前位置： SCI文献检索 > Ticks and Tick-Borne Diseases期刊下所有文献 > Diversity of two Theileria parva CD8+ antigens in cattle and buffalo-derived parasites in Tanzania.

Diversity of two Theileria parva CD8+ antigens in cattle and buffalo-derived parasites in Tanzania.

Abstract：

:Theileria parva is a tick-transmitted protozoan parasite that causes a disease called East Coast fever (ECF) in cattle. This important tick borne-disease (TBD) causes significant economic losses in cattle in many sub-Saharan countries, including Tanzania. Cattle immunization using Muguga cocktail has been recommended as an effective method for controlling ECF in pastoral farming systems in Tanzania. However, immunity provided through immunization is partially strain-specific. Therefore, the control of ECF in Tanzania is still a challenge due to inadequate epidemiological information. This study was conducted to assess genetic diversity of Tp1 and Tp2 genes from T. parva isolates that are recognized by CD8 + T-cells in cattle and buffalo. The Tp1 and Tp2 genes are currently under evaluation as candidates for inclusion in a subunit vaccine. A total of 130 blood samples collected from cattle which do not interact with buffalo (98), cattle co-grazing with buffalo (19) and buffalo (13) in Mara, Mbeya, Morogoro, Tanga, and Coast regions in Tanzania were used in this study. Genomic DNA was extracted from the blood samples, Tp1 and Tp2 genes were amplified using nested PCR and the PCR products were purified and sequenced. The partial sequencing of the Tp1 and Tp2 genes from T. parva isolates exhibited polymorphisms in both loci, including the epitope-containing regions. Results for sequence analysis showed that the overall nucleotide polymorphism (π) was 0.7% and 13.5% for Tp1 and Tp2, respectively. The Tajima's D and Fu's Fs test showed a negative value for both Tp1 and Tp2 genes, indicating deviations from neutrality due to a recent population expansion. The study further revealed a low to high level of genetic differentiations between populations and high genetic variability within populations. The study also revealed that most samples from the seven populations possessed several epitopes in antigens that were identical to those in the T. parva Muguga reference stock, which is the main component of the widely used live vaccine cocktail. Therefore, different strategic planning and cost-effective control measures should be implemented in order to reduce losses caused by ECF in the study areas.

journal_name

Ticks Tick Borne Dis

journal_title

Ticks and tick-borne diseases

authors

Kerario II,Chenyambuga SW,Mwega ED,Rukambile E,Simulundu E,Simuunza MC

doi

10.1016/j.ttbdis.2019.05.007

subject

Has Abstract

pub_date

2019-08-01 00:00:00

pages

1003-1017

issue

5

eissn

1877-959X

issn

1877-9603

pii

S1877-959X(18)30522-3

journal_volume

10

pub_type

杂志文章

相关文献

Ticks and Tick-Borne Diseases文献大全
  • Capybaras (Hydrochoerus hydrochaeris) as amplifying hosts of Rickettsia rickettsii to Amblyomma sculptum ticks: Evaluation during primary and subsequent exposures to R. rickettsii infection.

    abstract：:Rickettsia rickettsii is the agent of Brazilian spotted fever (BSF), the most lethal tick-borne disease in the western hemisphere. Amblyomma sculptum is the main vector of R. rickettsii in southeastern Brazil. Capybaras act as primary hosts for this tick species, and as amplifying hosts for R. rickettsii, creating new...

    journal_title：Ticks and tick-borne diseases

    pub_type： 杂志文章

    doi：10.1016/j.ttbdis.2020.101463

    authors： Ramírez-Hernández A,Uchoa F,Serpa MCA,Binder LC,Souza CE,Labruna MB

    更新日期：2020-09-01 00:00:00

  • Duration of Borrelia mayonii infectivity in an experimental mouse model for feeding Ixodes scapularis larvae.

    abstract：:A novel species within the Borrelia burgdorferi sensu lato complex, Borrelia mayonii, was recently described and found to be associated with Lyme borreliosis in the Upper Midwest of the United States. The blacklegged tick, Ixodes scapularis, is naturally infected with B. mayonii in the Upper Midwest and has been exper...

    journal_title：Ticks and tick-borne diseases

    pub_type： 杂志文章

    doi：10.1016/j.ttbdis.2016.11.002

    authors： Dolan MC,Breuner NE,Hojgaard A,Hoxmeier JC,Pilgard MA,Replogle AJ,Eisen L

    更新日期：2017-01-01 00:00:00

  • Rickettsia amblyommatis isolated from Amblyomma mixtum (Acari: Ixodida) from two sites in Panama.

    abstract：:Rickettsia amblyommatis is widely distributed in the Americas, and has been reported to infect different species of ticks within its distribution. In Panama, R. amblyommatis is the most common Rickettsia and its presence was molecularly detected in nine species of ticks and one flea species. This work described the is...

    journal_title：Ticks and tick-borne diseases

    pub_type： 杂志文章

    doi：10.1016/j.ttbdis.2020.101597

    authors： Bermúdez C S,Zaldívar Y,Domínguez A L,Hernández M,de Antinori MEB,Krawczak FS

    更新日期：2021-01-01 00:00:00

  • A five-year survey of tick species and identification of tick-borne bacteria in Sardinia, Italy.

    abstract：:Sardinia is a hotspot for studying tick-borne diseases in the Mediterranean region, where cases of notifiable tick-borne diseases are increasing. The aim of this study was to determine the presence of tick-borne bacteria of medical and veterinary importance in ixodid ticks collected from domestic and wild animals, hum...

    journal_title：Ticks and tick-borne diseases

    pub_type： 杂志文章

    doi：10.1016/j.ttbdis.2018.02.008

    authors： Chisu V,Foxi C,Mannu R,Satta G,Masala G

    更新日期：2018-03-01 00:00:00

  • First record of Babesia sp. in Antarctic penguins.

    abstract：:This is the first reported case of Babesia sp. in Antarctic penguins, specifically a population of Chinstrap penguins (Pygoscelis antarctica) in the Vapour Col penguin rookery in Deception Island, South Shetlands, Antarctica. We collected peripheral blood from 50 adult and 30 chick Chinstrap penguins. Examination of t...

    journal_title：Ticks and tick-borne diseases

    pub_type： 杂志文章

    doi：10.1016/j.ttbdis.2016.02.006

    authors： Montero E,González LM,Chaparro A,Benzal J,Bertellotti M,Masero JA,Colominas-Ciuró R,Vidal V,Barbosa A

    更新日期：2016-04-01 00:00:00

  • Babesia microti thioredoxin 3 is an effective antioxidant and involved in the response to antiprotozoal drugs.

    abstract：:The intra-erythrocytic apicomplexan Babesia microti is the predominant pathogen that causes human babesiosis, an infectious disease that occurs worldwide. B. microti relies on the antioxidant including thioredoxin system to maintain the redox balance during the erythrocytic stage. In the present study, the full-length...

    journal_title：Ticks and tick-borne diseases

    pub_type： 杂志文章

    doi：10.1016/j.ttbdis.2018.01.021

    authors： Huang J,Xiong K,Zhang H,Zhao Y,Cao J,Zhou Y,Gong H,Zhou J

    更新日期：2018-03-01 00:00:00

  • First molecular evidence of Coxiella burnetii infecting ticks in Cuba.

    abstract：:Coxiella burnetii is the causative agent of Q fever. In order to explore the occurrence of C. burnetii in ticks, samples were collected from horses, dogs and humans living in a Cuban occidental community. The species most commonly recovered were Amblyomma mixtum (67%), Rhipicephalus sanguineus s.l. (27%) and Dermacent...

    journal_title：Ticks and tick-borne diseases

    pub_type： 杂志文章

    doi：10.1016/j.ttbdis.2015.08.008

    authors： Noda AA,Rodríguez I,Miranda J,Contreras V,Mattar S

    更新日期：2016-02-01 00:00:00

  • The first clinical and laboratory evidence of co-infection by Anaplasma phagocytophilum and Ehrlichia canis in a Brazilian dog.

    abstract：:Information on Anaplasma phagocytophilum in Brazil is very restricted. The aim of this study was to report clinical, parasitological, hematological and molecular evidence of a natural A. phagocytophilum infection of an urban Brazilian dog. The dog was an eight-month-old male French bulldog. Veterinary clinical examina...

    journal_title：Ticks and tick-borne diseases

    pub_type： 杂志文章

    doi：10.1016/j.ttbdis.2015.01.003

    authors： Silveira JA,Valente PC,Paes PR,Vasconcelos AV,Silvestre BT,Ribeiro MF

    更新日期：2015-04-01 00:00:00

  • Molecular detection and characterization of Hepatozoon spp. in dogs from the central part of Turkey.

    abstract：:Canine hepatozoonosis is a tick-borne protozoal disease caused by Hepatozoon spp. Two species of Hepatozoon are currently known to infect dogs as Hepatozoon canis and H. americanum. Although H. canis generally causes a chronic infection with relatively mild clinical alterations compared to H. americanum, infection by ...

    journal_title：Ticks and tick-borne diseases

    pub_type： 杂志文章

    doi：10.1016/j.ttbdis.2015.03.004

    authors： Aydin MF,Sevinc F,Sevinc M

    更新日期：2015-04-01 00:00:00

  • Distinct Anaplasma phagocytophilum genotypes associated with Ixodes trianguliceps ticks and rodents in Central Europe.

    abstract：:Rodents are important reservoir hosts of tick-borne pathogens. Anaplasma phagocytophilum is the causative agent of granulocytic anaplasmosis of both medical and veterinary importance. In Europe, this pathogen is primarily transmitted by the Ixodes ricinus tick among a wide range of vertebrate hosts. However, to what d...

    journal_title：Ticks and tick-borne diseases

    pub_type： 杂志文章

    doi：10.1016/j.ttbdis.2014.07.012

    authors： Blaňarová L,Stanko M,Carpi G,Miklisová D,Víchová B,Mošanský L,Bona M,Derdáková M

    更新日期：2014-10-01 00:00:00

  • Infection of Ixodes spp. tick cells with different Anaplasma phagocytophilum isolates induces the inhibition of apoptotic cell death.

    abstract：:Anaplasma phagocytophilum is an intracellular rickettsial pathogen transmitted by Ixodes spp. ticks, which causes granulocytic anaplasmosis in humans, horses and dogs and tick-borne fever (TBF) in ruminants. In the United States, human granulocytic anaplasmosis (HGA) is highly prevalent while TBF has not been reported...

    journal_title：Ticks and tick-borne diseases

    pub_type： 杂志文章

    doi：10.1016/j.ttbdis.2015.07.001

    authors： Alberdi P,Ayllón N,Cabezas-Cruz A,Bell-Sakyi L,Zweygarth E,Stuen S,de la Fuente J

    更新日期：2015-09-01 00:00:00

  • Occurrence of Ixodiphagus hookeri (Hymenoptera: Encyrtidae) in Ixodes ricinus (Acari: Ixodidae) in southern Italy.

    abstract：:Natural enemies of ticks include the parasitoid wasp Ixodiphagus hookeri (Hymenoptera: Encyrtidae). The aim of this preliminary study was to investigate the occurrence of I. hookeri DNA in a community of ticks (Ixodes ricinus, Dermacentor marginatus, Hyalomma marginatum, Haemaphysalis inermis and Rhipicephalus turanic...

    journal_title：Ticks and tick-borne diseases

    pub_type： 杂志文章

    doi：10.1016/j.ttbdis.2015.01.001

    authors： Ramos RA,Campbell BE,Whittle A,Lia RP,Montarsi F,Parisi A,Dantas-Torres F,Wall R,Otranto D

    更新日期：2015-04-01 00:00:00

  • Parasitism of mustelids by ixodid ticks (Acari: Ixodidae), Maine and New Hampshire, U.S.A.

    abstract：:Ticks collected from mustelids from four counties in Maine and one in New Hampshire were identified after harvest. Of the 18 fishers Martes pennanti Erxleben, two mink Neovison vison Schreber, and one long-tailed weasel Mustela frenata Lichtenstein, 589 ticks were collected and identified. They were identified as, in ...

    journal_title：Ticks and tick-borne diseases

    pub_type： 杂志文章

    doi：10.1016/j.ttbdis.2014.02.001

    authors： Lubelczyk C,Lacombe EH,Elias SP,Beati L,Rand PW,Smith RP Jr

    更新日期：2014-06-01 00:00:00

  • The role of Ixodes scapularis, Borrelia burgdorferi and wildlife hosts in Lyme disease prevalence: A quantitative review.

    abstract：:Due to the ongoing expansion of Ixodes scapularis (blacklegged tick) throughout the northeastern and midwestern United States, there is need to identify the role wildlife hosts play in the establishment and maintenance of tick populations. To quantify and synthesize the patterns of I. scapularis and Borrelia burgdorfe...

    journal_title：Ticks and tick-borne diseases

    pub_type： 杂志文章,meta分析,评审

    doi：10.1016/j.ttbdis.2018.04.006

    authors： Halsey SJ,Allan BF,Miller JR

    更新日期：2018-07-01 00:00:00

  • Dissociating effect of salivary gland extract from Ixodes ricinus on human fibroblasts: Potential impact on Borrelia transmission.

    abstract：:Understanding the mechanism of pathogen transmission is essential for the development of strategies to reduce arthropod-borne diseases. The pharmaco- and immunomodulatory properties of insect and acarine saliva play an essential role in the efficiency of pathogen transmission. The skin as the site where arthropod sali...

    journal_title：Ticks and tick-borne diseases

    pub_type： 杂志文章

    doi：10.1016/j.ttbdis.2018.12.005

    authors： Boeuf A,Schnell G,Bernard Q,Kern A,Westermann B,Ehret-Sabatier L,Grillon A,Schramm F,Jaulhac B,Boulanger N

    更新日期：2019-02-01 00:00:00

  • Non-surgical management of spontaneous splenic rupture due to Babesia microti infection.

    abstract：:Babesiosis is an emerging tick-borne infection. We describe 2 hospitalized patients from the United States with spontaneous splenic rupture attributable to Babesia microti infection. The first patient was a 36-year-old previously healthy man with a low-grade splenic rupture not requiring surgical intervention. The sec...

    journal_title：Ticks and tick-borne diseases

    pub_type： 杂志文章

    doi：10.1016/j.ttbdis.2011.08.001

    authors： El Khoury MY,Gandhi R,Dandache P,Lombardo G,Wormser GP

    更新日期：2011-12-01 00:00:00

  • Development of an efficient antitick natural formulation for the control of acaricide-resistant ticks on livestock.

    abstract：:Animal production has a key role in global economic development and food security. Ticks, specifically Rhipicephalus microplus cause substantial economic and health impacts on more than eighty percent of the world cattle population. Though synthetic acaricides play a major role in tick management, their injudicious us...

    journal_title：Ticks and tick-borne diseases

    pub_type： 杂志文章

    doi：10.1016/j.ttbdis.2021.101655

    authors： Shanmuganath C,Kumar S,Singh R,Sharma AK,Saminathan M,Saini M,Chigure G,Fular A,Kumar R,Juliet S,Upadhaya D,Kumar B,Srivastava S,Ghosh S

    更新日期：2021-01-19 00:00:00

  • Validation of a serological test for the diagnosis of canine rickettsial disease.

    abstract：:Canine vector borne diseases include a variety of illnesses affecting domestic dogs worldwide. Clinical abnormalities are often nonspecific during rickettsial infections, and coinfections caused by other tick-transmitted agents may be common. The aim of this study was to validate a differential serological assay for t...

    journal_title：Ticks and tick-borne diseases

    pub_type： 杂志文章

    doi：10.1016/j.ttbdis.2012.10.024

    authors： Masu G,Sechi S,Cocco R,Chisu V,Tanda A,Lollai S,Masala G

    更新日期：2012-12-01 00:00:00

  • Occupational risk for personnel working in veterinary clinics through exposure to vectors of rickettsial pathogens.

    abstract：:Workers at veterinary clinics are exposed to zoonotic pathogens, which, though infrequently, can lead to serious consequences. The aim of the present study was to estimate the seroprevalence for rickettsial pathogens in veterinary clinic personnel in Ciudad Juárez, Chihuahua, Mexico. Voluntary participants included 10...

    journal_title：Ticks and tick-borne diseases

    pub_type： 杂志文章

    doi：10.1016/j.ttbdis.2018.10.012

    authors： Escárcega-Ávila AM,de la Mora-Covarrubias A,Quezada-Casasola A,Jiménez-Vega F

    更新日期：2019-02-01 00:00:00

  • Presence of Borrelia in different populations of Ixodes pararicinus from northwestern Argentina.

    abstract：:This work was performed to evaluate the presence of Borrelia in different populations of Ixodes pararicinus from northwestern Argentina (Jujuy, Salta and Tucumán provinces). Questing adults and nymphs of I. pararicinus were collected from vegetation, and I. pararicinus nymphs were also collected on birds. Eighty-two t...

    journal_title：Ticks and tick-borne diseases

    pub_type： 杂志文章

    doi：10.1016/j.ttbdis.2017.02.008

    authors： Saracho Bottero MN,Sebastian PS,Carvalho LA,Claps LG,Mastropaolo M,Mangold AJ,Venzal JM,Nava S

    更新日期：2017-06-01 00:00:00

  • Demonstration of lumpy skin disease virus infection in Amblyomma hebraeum and Rhipicephalus appendiculatus ticks using immunohistochemistry.

    abstract：:Lumpy skin disease (LSD) is caused by lumpy skin disease virus (LSDV), a member of the genus Capripoxvirus. Transmission of the virus has been associated with haematophagous insects such as Stomoxys calcitrans as well as Aedes and Culex species of mosquitoes. Recent studies have reported the transmission of the virus ...

    journal_title：Ticks and tick-borne diseases

    pub_type： 杂志文章

    doi：10.1016/j.ttbdis.2013.09.010

    authors： Lubinga JC,Clift SJ,Tuppurainen ES,Stoltsz WH,Babiuk S,Coetzer JA,Venter EH

    更新日期：2014-03-01 00:00:00

  • Simultaneous detection of Theileria annulata and Theileria orientalis infections using recombinase polymerase amplification.

    abstract：:Theileriosis is a disease of domesticated animals in tropical and subtropical countries and causes significant reductions in livestock productivity. The arid region of Punjab in Pakistan is notorious for the presence of the vector tick (Acari: Ixodidae) and tick-borne diseases, such as theileriosis and babesiosis. The...

    journal_title：Ticks and tick-borne diseases

    pub_type： 杂志文章

    doi：10.1016/j.ttbdis.2018.03.028

    authors： Hassan MA,Liu J,Sajid MS,Rashid M,Mahmood A,Abbas Q,Guan G,Yin H,Luo J

    更新日期：2018-05-01 00:00:00

  • Detection and molecular characterization of tick-borne pathogens infecting sheep and goats in Blue Nile and West Kordofan states in Sudan.

    abstract：:Tick-borne pathogens (TBPs) are common in livestock of sub-Saharan Africa. However, information regarding TBPs in sheep and goats in Sudan is limited. In this study, 178 blood samples of sheep and goats in Blue Nile and West Kordofan states were investigated for TBPs using PCR. Overall, 110 (61.8%) samples were found ...

    journal_title：Ticks and tick-borne diseases

    pub_type： 杂志文章

    doi：10.1016/j.ttbdis.2018.01.014

    authors： Lee SH,Mossaad E,Ibrahim AM,Ismail AA,Adjou Moumouni PF,Liu M,Ringo AE,Gao Y,Guo H,Li J,Efstratiou A,Musinguzi P,Angara TEE,Suganuma K,Inoue N,Xuan X

    更新日期：2018-03-01 00:00:00

  • Preventing tick-bites among children in Indiana, USA: An analysis of factors associated with parental protective behaviors.

    abstract：:Despite evidence to the effect that there is low parental adoption of tick-bite personal protective behavior (PPB) for their children - a population at high risk for tick exposure, very limited information is available on factors associated with parental adoption of PPB. The objective of this study was to identify the...

    journal_title：Ticks and tick-borne diseases

    pub_type： 杂志文章

    doi：10.1016/j.ttbdis.2020.101647

    authors： Omodior O,Anderson KR,Clark W,Eze P,Donohoe H

    更新日期：2021-03-01 00:00:00

  • Toxic effects of various solvents against Rhipicephalus (Boophilus) annulatus.

    abstract：:The current need of identification of a new acaricidal agent which is acceptable to public as environmentally safe is a daring task. Use of herbal acaricides is such an alternative. Most of the herbal extracts or fractions are dissolved in polar or non-polar solvents or detergents before tested for acaricidal activity...

    journal_title：Ticks and tick-borne diseases

    pub_type： 杂志文章

    doi：10.1016/j.ttbdis.2011.04.001

    authors： Ravindran R,Juliet S,Kumar KG,Sunil AR,Nair SN,Amithamol KK,Rawat AK,Ghosh S

    更新日期：2011-09-01 00:00:00

  • Survey of ticks in French Guiana.

    abstract：:In this study, we examine the current pattern of tick diversity and host use in French Guiana, South America, from 97 sampling localities encompassing peri-urban, rural and natural habitats. We collected 3395 ticks, including 1485 specimens from 45 vertebrate species (humans, domestic and wild animals) and 1910 questi...

    journal_title：Ticks and tick-borne diseases

    pub_type： 杂志文章

    doi：10.1016/j.ttbdis.2018.09.003

    authors： Binetruy F,Chevillon C,de Thoisy B,Garnier S,Duron O

    更新日期：2019-01-01 00:00:00

  • Epidemiology and cost of hospital care for Lyme borreliosis in Germany: lessons from a health care utilization database analysis.

    abstract：:To date, relatively little is known about the economic and medical impact of Lyme borreliosis (LB) on European health care systems, especially for the inpatient sector. This retrospective analysis is based on data provided for the years 2007-2011 by a German statutory health insurance company (DAK-Gesundheit) covering...

    journal_title：Ticks and tick-borne diseases

    pub_type： 杂志文章

    doi：10.1016/j.ttbdis.2014.09.004

    authors： Lohr B,Müller I,Mai M,Norris DE,Schöffski O,Hunfeld KP

    更新日期：2015-02-01 00:00:00

  • Single-tube real-time PCR assay for differentiation of Ixodes affinis and Ixodes scapularis.

    abstract：:Ixodes affinis Neumann (1899) and Ixodes scapularis Say (1821) are tick vectors of the etiologic agent of Lyme disease, Borrelia burgdorferi sensu stricto. Ixodes affinis and I. scapularis are morphologically very similar, and as they are sympatric in the mid- and south-Atlantic U.S. coastal states, their accurate ide...

    journal_title：Ticks and tick-borne diseases

    pub_type： 杂志文章

    doi：10.1016/j.ttbdis.2013.08.003

    authors： Wright CL,Hynes WL,White BT,Marshall MN,Gaff HD,Gauthier DT

    更新日期：2014-02-01 00:00:00

  • Verification of post-chemotherapeutic clearance of Theileria equi through concordance of nested PCR and immunoblot.

    abstract：:Certain countries including the United States remain non-endemic for particular infectious diseases such as equine piroplasmosis through import restrictions and surveillance. Endemic regions often employ premunition as the primary method to control disease, however in non-endemic countries, chemosterilization combined...

    journal_title：Ticks and tick-borne diseases

    pub_type： 杂志文章

    doi：10.1016/j.ttbdis.2017.08.007

    authors： Wise LN,Kappmeyer LS,Silva MG,White SN,Grause JF,Knowles DP

    更新日期：2018-02-01 00:00:00

  • Studies of Anaplasma phagocytophilum in sheep experimentally infected with the human NY-18 isolate: characterization of tick feeding sites.

    abstract：:Anaplasma phagocytophilum, transmitted by ticks of the genus Ixodes, was first described in Scotland as the agent of tick-borne fever in sheep and more recently as the cause of human granulocytic anaplasmosis in the U.S. and Europe. We previously reported sheep as an experimental host for the human NY-18 isolate of A....

    journal_title：Ticks and tick-borne diseases

    pub_type： 杂志文章

    doi：10.1016/j.ttbdis.2014.05.014

    authors： Reppert E,Galindo RC,Ayllón N,Breshears MA,Kocan KM,Blouin EF,de la Fuente J

    更新日期：2014-10-01 00:00:00