Quantification of Facial Traits.

Abstract:

:Measuring facial traits by quantitative means is a prerequisite to investigate epidemiological, clinical, and forensic questions. This measurement process has received intense attention in recent years. We divided this process into the registration of the face, landmarking, morphometric quantification, and dimension reduction. Face registration is the process of standardizing pose and landmarking annotates positions in the face with anatomic description or mathematically defined properties (pseudolandmarks). Morphometric quantification computes pre-specified transformations such as distances. Landmarking: We review face registration methods which are required by some landmarking methods. Although similar, face registration and landmarking are distinct problems. The registration phase can be seen as a pre-processing step and can be combined independently with a landmarking solution. Existing approaches for landmarking differ in their data requirements, modeling approach, and training complexity. In this review, we focus on 3D surface data as captured by commercial surface scanners but also cover methods for 2D facial pictures, when methodology overlaps. We discuss the broad categories of active shape models, template based approaches, recent deep-learning algorithms, and variations thereof such as hybrid algorithms. The type of algorithm chosen depends on the availability of pre-trained models for the data at hand, availability of an appropriate landmark set, accuracy characteristics, and training complexity. Quantification: Landmarking of anatomical landmarks is usually augmented by pseudo-landmarks, i.e., indirectly defined landmarks that densely cover the scan surface. Such a rich data set is not amenable to direct analysis but is reduced in dimensionality for downstream analysis. We review classic dimension reduction techniques used for facial data and face specific measures, such as geometric measurements and manifold learning. Finally, we review symmetry registration and discuss reliability.

journal_name

Front Genet

journal_title

Frontiers in genetics

authors

Böhringer S,de Jong MA

doi

10.3389/fgene.2019.00397

subject

Has Abstract

pub_date

2019-05-24 00:00:00

pages

397

issn

1664-8021

journal_volume

10

pub_type

杂志文章,评审
  • Genetic and Clinical Analyses of 13 Chinese Families With Cystine Urolithiasis and Identification of 15 Novel Pathogenic Variants in SLC3A1 and SLC7A9.

    abstract:Background:Cystinuria is a rare genetic disorder characterized by defective renal reabsorption of cystine, ornithine, arginine, and lysine. The increased urinary excretion of cystine results in the development of cystine urolithiasis (CU). The mutated SLC3A1 and SLC7A9 genes are the cause of CU, a global disorder. Its ...

    journal_title:Frontiers in genetics

    pub_type: 杂志文章

    doi:10.3389/fgene.2020.00074

    authors: Li C,Yang Y,Zheng Y,Shen F,Liu L,Li Y,Li L,Zhao Y

    更新日期:2020-02-18 00:00:00

  • Association of the Lactase Persistence Haplotype Block With Disease Risk in Populations of European Descent.

    abstract::Among people of European descent, the ability to digest lactose into adulthood arose via strong positive selection of a highly advantageous allele encompassing the lactase gene. Lactose-tolerant and intolerant individuals may have different disease risks due to the shared genetics of their haplotype block. Therefore, ...

    journal_title:Frontiers in genetics

    pub_type: 杂志文章

    doi:10.3389/fgene.2020.558762

    authors: Joslin SEK,Durbin-Johnson BP,Britton M,Settles ML,Korf I,Lemay DG

    更新日期:2020-10-29 00:00:00

  • Severe Phenotype in a Patient With Homozygous 15q21.2 Microdeletion Involving BCL2L10, GNB5, and MYO5C Genes, Resembling Infantile Developmental Disorder With Cardiac Arrhythmias (IDDCA).

    abstract::Homozygous and compound heterozygous mutations in GNB5 gene have been associated with a wide spectrum of clinical presentations, ranging from neurodevelopmental issues with or without cardiac arrhythmia (LADCI) to severe developmental delay with epileptic encephalopathy, retinal dystrophy, and heart rhythm abnormaliti...

    journal_title:Frontiers in genetics

    pub_type: 杂志文章

    doi:10.3389/fgene.2020.00399

    authors: Sciacca FL,Ciaccio C,Fontana F,Strano C,Gilardoni F,Pantaleoni C,D'Arrigo S

    更新日期:2020-05-13 00:00:00

  • PASE: a novel method for functional prediction of amino acid substitutions based on physicochemical properties.

    abstract:BACKGROUND:Non-synonymous single-nucleotide polymorphisms (nsSNPs) within the coding regions of genes causing amino acid substitutions (AASs) may have a large impact on protein function. The possibilities to identify nsSNPs across genomes have increased notably with the advent of next-generation sequencing technologies...

    journal_title:Frontiers in genetics

    pub_type: 杂志文章

    doi:10.3389/fgene.2013.00021

    authors: Li X,Kierczak M,Shen X,Ahsan M,Carlborg O,Marklund S

    更新日期:2013-03-06 00:00:00

  • DNA methylation changes in the postmortem dorsolateral prefrontal cortex of patients with schizophrenia.

    abstract:BACKGROUND:Schizophrenia is a complex psychiatric disorder with a lifetime morbidity rate of 0.5-1.0%. The pathophysiology of schizophrenia still remains obscure. Accumulating evidence indicates that DNA methylation, which is the addition of a methyl group to the cytosine in a CpG dinucleotide, might play an important ...

    journal_title:Frontiers in genetics

    pub_type: 杂志文章

    doi:10.3389/fgene.2014.00280

    authors: Numata S,Ye T,Herman M,Lipska BK

    更新日期:2014-08-26 00:00:00

  • Draft Genome and Complete Hox-Cluster Characterization of the Sterlet (Acipenser ruthenus).

    abstract::Background: Sturgeons (Chondrostei: Acipenseridae) are a group of "living fossil" fishes at a basal position among Actinopteri. They have raised great public interest due to their special evolutionary position, species conservation challenges, as well as their highly-prized eggs (caviar). The sterlet, Acipenser ruthen...

    journal_title:Frontiers in genetics

    pub_type: 杂志文章

    doi:10.3389/fgene.2019.00776

    authors: Cheng P,Huang Y,Du H,Li C,Lv Y,Ruan R,Ye H,Bian C,You X,Xu J,Liang X,Shi Q,Wei Q

    更新日期:2019-09-05 00:00:00

  • Novel Y-Chromosome Long Non-Coding RNAs Expressed in Human Male CNS During Early Development.

    abstract::Global microarray gene expression analyses previously demonstrated differences in female and male embryos during neurodevelopment. In particular, before sexual maturation of the gonads, the differences seem to concentrate on the expression of genes encoded on the X- and Y-chromosomes. To investigate genome-wide differ...

    journal_title:Frontiers in genetics

    pub_type: 杂志文章

    doi:10.3389/fgene.2019.00891

    authors: Johansson MM,Pottmeier P,Suciu P,Ahmad T,Zaghlool A,Halvardson J,Darj E,Feuk L,Peuckert C,Jazin E

    更新日期:2019-09-24 00:00:00

  • Prospects and challenges for the conservation of farm animal genomic resources, 2015-2025.

    abstract::Livestock conservation practice is changing rapidly in light of policy developments, climate change and diversifying market demands. The last decade has seen a step change in technology and analytical approaches available to define, manage and conserve Farm Animal Genomic Resources (FAnGR). However, these rapid change...

    journal_title:Frontiers in genetics

    pub_type: 杂志文章

    doi:10.3389/fgene.2015.00314

    authors: Bruford MW,Ginja C,Hoffmann I,Joost S,Orozco-terWengel P,Alberto FJ,Amaral AJ,Barbato M,Biscarini F,Colli L,Costa M,Curik I,Duruz S,Ferenčaković M,Fischer D,Fitak R,Groeneveld LF,Hall SJ,Hanotte O,Hassan FU,Helsen

    更新日期:2015-10-21 00:00:00

  • The Impact of Pathway Database Choice on Statistical Enrichment Analysis and Predictive Modeling.

    abstract::Pathway-centric approaches are widely used to interpret and contextualize -omics data. However, databases contain different representations of the same biological pathway, which may lead to different results of statistical enrichment analysis and predictive models in the context of precision medicine. We have performe...

    journal_title:Frontiers in genetics

    pub_type: 杂志文章

    doi:10.3389/fgene.2019.01203

    authors: Mubeen S,Hoyt CT,Gemünd A,Hofmann-Apitius M,Fröhlich H,Domingo-Fernández D

    更新日期:2019-11-22 00:00:00

  • MTGO-SC, A Tool to Explore Gene Modules in Single-Cell RNA Sequencing Data.

    abstract::The identification of functional modules in gene interaction networks is a key step in understanding biological processes. Network interpretation is essential for unveiling biological mechanisms, candidate biomarkers, or potential targets for drug discovery/repositioning. Plenty of biological module identification alg...

    journal_title:Frontiers in genetics

    pub_type: 杂志文章

    doi:10.3389/fgene.2019.00953

    authors: Nazzicari N,Vella D,Coronnello C,Di Silvestre D,Bellazzi R,Marini S

    更新日期:2019-10-09 00:00:00

  • Using The Cancer Genome Atlas as an Inquiry Tool in the Undergraduate Classroom.

    abstract::Undergraduate students in the biomedical sciences are often interested in future health-focused careers. This presents opportunities for instructors in genetics, molecular biology, and cancer biology to capture their attention using lab experiences built around clinically relevant data. As biomedical science in genera...

    journal_title:Frontiers in genetics

    pub_type: 杂志文章

    doi:10.3389/fgene.2020.573992

    authors: Hankey W,Zanghi N,Crow MM,Dow WH,Kratz A,Robinson AM,Robinson MR,Segarra VA

    更新日期:2020-12-16 00:00:00

  • A Quasi-Domesticate Relic Hybrid Population of Saccharomyces cerevisiae × S. paradoxus Adapted to Olive Brine.

    abstract::The adaptation of the yeast Saccharomyces cerevisiae to man-made environments for the fermentation of foodstuffs and beverages illustrates the scientific, social, and economic relevance of microbe domestication. Here we address a yet unexplored aspect of S. cerevisiae domestication, that of the emergence of lineages h...

    journal_title:Frontiers in genetics

    pub_type: 杂志文章

    doi:10.3389/fgene.2019.00449

    authors: Pontes A,Čadež N,Gonçalves P,Sampaio JP

    更新日期:2019-05-29 00:00:00

  • Leveraging ethnic group incidence variation to investigate genetic susceptibility to glioma: a novel candidate SNP approach.

    abstract:OBJECTIVES:Using a novel candidate SNP approach, we aimed to identify a possible genetic basis for the higher glioma incidence in Whites relative to East Asians and African-Americans. METHODS:  We hypothesized that genetic regions containing SNPs with extreme differences in allele frequencies across ethnicities are mo...

    journal_title:Frontiers in genetics

    pub_type: 杂志文章

    doi:10.3389/fgene.2012.00203

    authors: Jacobs DI,Walsh KM,Wrensch M,Wiencke J,Jenkins R,Houlston RS,Bondy M,Simon M,Sanson M,Gousias K,Schramm J,Labussière M,Di Stefano AL,Wichmann HE,Müller-Nurasyid M,Schreiber S,Franke A,Moebus S,Eisele L,Dewan AT,Du

    更新日期:2012-10-12 00:00:00

  • Construction and Analysis of a ceRNA Network Reveals Potential Prognostic Markers in Colorectal Cancer.

    abstract::Colorectal cancer (CRC) is one of the leading causes of cancer-related deaths worldwide and is derived from an accumulation of genetic and epigenetic changes. This study explored potential prognostic markers in CRC via the construction and in-depth analysis of a competing endogenous RNA (ceRNA) network, which was gene...

    journal_title:Frontiers in genetics

    pub_type: 杂志文章

    doi:10.3389/fgene.2020.00418

    authors: Guo L,Yang G,Kang Y,Li S,Duan R,Shen L,Jiang W,Qian B,Yin Z,Liang T

    更新日期:2020-05-08 00:00:00

  • The establishment of Central American migratory corridors and the biogeographic origins of seasonally dry tropical forests in Mexico.

    abstract::Biogeography and community ecology can mutually illuminate the formation of a regional species pool or biome. Here, we apply phylogenetic methods to a large and diverse plant clade, Malpighiaceae, to characterize the formation of its species pool in Mexico, and its occupancy of the seasonally dry tropical forest (SDTF...

    journal_title:Frontiers in genetics

    pub_type: 杂志文章

    doi:10.3389/fgene.2014.00433

    authors: Willis CG,Franzone BF,Xi Z,Davis CC

    更新日期:2014-12-19 00:00:00

  • Transcript Isoforms of SLC7A11-AS1 Are Associated With Varicocele-Related Male Infertility.

    abstract::Oxidative stress is one of the crucial mediators of varicocele-related male infertility. Recently, roles of long noncoding RNAs (lncRNAs) in oxidative stress have begun to emerge, however, little is known about their role in male infertility. The aim of this study was to determine the role of lncRNA SLC7A11-AS1 in var...

    journal_title:Frontiers in genetics

    pub_type: 杂志文章

    doi:10.3389/fgene.2020.01015

    authors: Sanei-Ataabadi N,Mowla SJ,Nasr-Esfahani MH

    更新日期:2020-09-11 00:00:00

  • High-Density Genetic Linkage Maps Provide Novel Insights Into ZW/ZZ Sex Determination System and Growth Performance in Mud Crab (Scylla paramamosain).

    abstract::Mud crab, Scylla paramamosain is one of the most important crustacean species in global aquaculture. To determine the genetic basis of sex and growth-related traits in S. paramamosain, a high-density genetic linkage map with 16,701 single nucleotide polymorphisms (SNPs) was constructed using SLAF-seq and a full-sib fa...

    journal_title:Frontiers in genetics

    pub_type: 杂志文章

    doi:10.3389/fgene.2019.00298

    authors: Waiho K,Shi X,Fazhan H,Li S,Zhang Y,Zheng H,Liu W,Fang S,Ikhwanuddin M,Ma H

    更新日期:2019-04-05 00:00:00

  • Redundancy of the genetic code enables translational pausing.

    abstract::The codon redundancy ("degeneracy") found in protein-coding regions of mRNA also prescribes Translational Pausing (TP). When coupled with the appropriate interpreters, multiple meanings and functions are programmed into the same sequence of configurable switch-settings. This additional layer of Ontological Prescriptiv...

    journal_title:Frontiers in genetics

    pub_type: 杂志文章,评审

    doi:10.3389/fgene.2014.00140

    authors: D'Onofrio DJ,Abel DL

    更新日期:2014-05-20 00:00:00

  • Analysis of Transcriptome and Epitranscriptome in Plants Using PacBio Iso-Seq and Nanopore-Based Direct RNA Sequencing.

    abstract::Nanopore sequencing from Oxford Nanopore Technologies (ONT) and Pacific BioSciences (PacBio) single-molecule real-time (SMRT) long-read isoform sequencing (Iso-Seq) are revolutionizing the way transcriptomes are analyzed. These methods offer many advantages over most widely used high-throughput short-read RNA sequenci...

    journal_title:Frontiers in genetics

    pub_type: 杂志文章,评审

    doi:10.3389/fgene.2019.00253

    authors: Zhao L,Zhang H,Kohnen MV,Prasad KVSK,Gu L,Reddy ASN

    更新日期:2019-03-21 00:00:00

  • Identification and Validation of Key Genes Associated With Systemic Sclerosis-Related Pulmonary Hypertension.

    abstract::Systemic sclerosis-associated with pulmonary arterial hypertension (SSc-PAH) is still a major cause of SSc related deaths. Early diagnosis and prompt treatment are crucial to reduce the mortality of patients with SSc-PAH. To screen the candidate biomarkers and potential therapeutic targets for SSc-PAH, we analyzed the...

    journal_title:Frontiers in genetics

    pub_type: 杂志文章

    doi:10.3389/fgene.2020.00816

    authors: Zheng JN,Li Y,Yan YM,Shi H,Zou TT,Shao WQ,Wang Q

    更新日期:2020-07-24 00:00:00

  • Delayed development induced by toxicity to the host can be inherited by a bacterial-dependent, transgenerational effect.

    abstract::Commensal gut bacteria in many species including flies are integral part of their host, and are known to influence its development and homeostasis within generation. Here we report an unexpected impact of host-microbe interactions, which mediates multi-generational, non-Mendelian inheritance of a stress-induced phenot...

    journal_title:Frontiers in genetics

    pub_type: 杂志文章

    doi:10.3389/fgene.2014.00027

    authors: Fridmann-Sirkis Y,Stern S,Elgart M,Galili M,Zeisel A,Shental N,Soen Y

    更新日期:2014-02-25 00:00:00

  • Controlling variation in the comet assay.

    abstract::Variability of the comet assay is a serious issue, whether it occurs from experiment to experiment in the same laboratory, or between different laboratories analysing identical samples. Do we have to live with high variability, just because the comet assay is a biological assay rather than analytical chemistry? Numero...

    journal_title:Frontiers in genetics

    pub_type: 杂志文章

    doi:10.3389/fgene.2014.00359

    authors: Collins AR,El Yamani N,Lorenzo Y,Shaposhnikov S,Brunborg G,Azqueta A

    更新日期:2014-10-20 00:00:00

  • The Challenge of Stratifying Obesity: Attempts in the Quebec Family Study.

    abstract::Background and aims: Obesity is a major health problem worldwide. Given the heterogeneous obesity phenotype, an optimal obesity stratification would improve clinical management. Since obesity has a strong genetic component, we aimed to develop a polygenic risk score (PRS) to stratify obesity according to the genetic b...

    journal_title:Frontiers in genetics

    pub_type: 杂志文章

    doi:10.3389/fgene.2019.00994

    authors: de Toro-Martín J,Guénard F,Bouchard C,Tremblay A,Pérusse L,Vohl MC

    更新日期:2019-10-10 00:00:00

  • Detecting Diagnostic Biomarkers of Alzheimer's Disease by Integrating Gene Expression Data in Six Brain Regions.

    abstract::Alzheimer's disease (AD) is a neurodegenerative and progressive disease, which often causes irreversible damages to the cerebrum. The pathogenesis of AD is far from being fully understood, while there are some popular hypotheses. So far, the diagnosis of AD relies only on clinical screening in the form of imaging tech...

    journal_title:Frontiers in genetics

    pub_type: 杂志文章

    doi:10.3389/fgene.2019.00157

    authors: Wang L,Liu ZP

    更新日期:2019-03-12 00:00:00

  • PIANO: A Web Server for Pseudouridine-Site (Ψ) Identification and Functional Annotation.

    abstract::Known as the "fifth RNA nucleotide", pseudouridine (Ψ or psi) is the first-discovered and most abundant RNA modification occurring at the Uridine site, and it plays a prominent role in a number of biological processes. Thousands of Ψ sites have been identified within different biological contexts thanks to the advance...

    journal_title:Frontiers in genetics

    pub_type: 杂志文章

    doi:10.3389/fgene.2020.00088

    authors: Song B,Tang Y,Wei Z,Liu G,Su J,Meng J,Chen K

    更新日期:2020-03-12 00:00:00

  • Epigenetic Modifications in Acute Myeloid Leukemia: Prognosis, Treatment, and Heterogeneity.

    abstract::Leukemia, specifically acute myeloid leukemia (AML), is a common malignancy that can be differentiated into multiple subtypes based on leukemogenic history and etiology. Although genetic aberrations, particularly cytogenetic abnormalities and mutations in known oncogenes, play an integral role in AML development, epig...

    journal_title:Frontiers in genetics

    pub_type: 杂志文章,评审

    doi:10.3389/fgene.2019.00133

    authors: Goldman SL,Hassan C,Khunte M,Soldatenko A,Jong Y,Afshinnekoo E,Mason CE

    更新日期:2019-03-01 00:00:00

  • Genome-Wide Association Study Uncovers Novel Genomic Regions Associated With Coleoptile Length in Hard Winter Wheat.

    abstract::Successful seedling establishment depends on the optimum depth of seed placement especially in drought-prone conditions, providing an opportunity to exploit subsoil water and increase winter survival in winter wheat. Coleoptile length is a key determinant for the appropriate depth at which seed can be sown. Thus, unde...

    journal_title:Frontiers in genetics

    pub_type: 杂志文章

    doi:10.3389/fgene.2019.01345

    authors: Sidhu JS,Singh D,Gill HS,Brar NK,Qiu Y,Halder J,Al Tameemi R,Turnipseed B,Sehgal SK

    更新日期:2020-02-05 00:00:00

  • Functional Analyses of a Novel Splice Variant in the CHD7 Gene, Found by Next Generation Sequencing, Confirm Its Pathogenicity in a Spanish Patient and Diagnose Him with CHARGE Syndrome.

    abstract::Mutations in CHD7 have been shown to be a major cause of CHARGE syndrome, which presents many symptoms and features common to other syndromes making its diagnosis difficult. Next generation sequencing (NGS) of a panel of intellectual disability related genes was performed in an adult patient without molecular diagnosi...

    journal_title:Frontiers in genetics

    pub_type: 杂志文章

    doi:10.3389/fgene.2018.00007

    authors: Villate O,Ibarluzea N,Fraile-Bethencourt E,Valenzuela A,Velasco EA,Grozeva D,Raymond FL,Botella MP,Tejada MI

    更新日期:2018-01-26 00:00:00

  • A Novel Loss-of-Function Variant in Transmembrane Protein 263 (TMEM263) of Autosomal Dwarfism in Chicken.

    abstract::Autosomal dwarfism (adw) in chickens is a growth deficiency caused by a recessive mutation. Characteristic for adw is an approximately 30% growth reduction with short shank. The adw variant was first recognized in the Cornell K-strain of White Leghorns, but the genetic causal variant remained unknown. To identify the ...

    journal_title:Frontiers in genetics

    pub_type: 杂志文章

    doi:10.3389/fgene.2018.00193

    authors: Wu Z,Derks MFL,Dibbits B,Megens HJ,Groenen MAM,Crooijmans RPMA

    更新日期:2018-06-07 00:00:00

  • Predicting the Disease Genes of Multiple Sclerosis Based on Network Representation Learning.

    abstract::Multiple sclerosis (MS) is an autoimmune disease for which it is difficult to find exact disease-related genes. Effectively identifying disease-related genes would contribute to improving the treatment and diagnosis of multiple sclerosis. Current methods for identifying disease-related genes mainly focus on the hypoth...

    journal_title:Frontiers in genetics

    pub_type: 杂志文章

    doi:10.3389/fgene.2020.00328

    authors: Liu H,Guan J,Li H,Bao Z,Wang Q,Luo X,Xue H

    更新日期:2020-04-21 00:00:00