Sacral Myeloradiculitis: An Uncommon Complication of Genital Herpes Infection.

Abstract:

:Herpes simplex virus 1 and 2 infections affect up to 50 million people in the United States, with a natural history of recurrent viral shedding with or without recurrence of symptoms. Although many patients remain asymptomatic or with mild symptoms, a spectrum of rare but significant nervous system complications have been reported. Although urinary retention and constipation associated with genital herpesvirus infections is often attributed to painful genital ulcerations, herpesvirus-associated lumbosacral myeloradiculitis has been reported in adults. Here, we report an 18-year-old man with constipation, urinary retention, perineal paresthesias, and erectile dysfunction in the setting of a genital herpes infection. His workup was notable for a cerebrospinal fluid pleocytosis and MRI with enhancement of the cauda equina and nerve roots, all of which are consistent with sacral myeloradiculitis. The patient was treated with a 3-week course of intravenous acyclovir with complete resolution of symptoms. Pediatric practitioners should be aware of this complication of anogenital herpes simplex virus infection because appropriate diagnosis has implications for treatment delivery and duration.

journal_name

Pediatrics

journal_title

Pediatrics

authors

Whalen AM,Mateo CM,Growdon AS,Miller AF

doi

10.1542/peds.2018-2631

subject

Has Abstract

pub_date

2019-07-01 00:00:00

issue

1

eissn

0031-4005

issn

1098-4275

pii

peds.2018-2631

journal_volume

144

pub_type

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