Aging and Hematopoiesis.

Abstract:

:In hematopoiesis, mature blood cells, granulocytes, erythrocytes, and megakaryocytes originate from hematopoietic stem cells. With age, changes in hematopoiesis may have clinical consequences: defective immune responses, cytopenias (most commonly anemia and lymphopenia), hematological malignancy, and effects mediated by hematopoietic cells in other organs. Clonal hematopoiesis is commonly seen with aging and has been associated with both blood concerns and atherosclerosis, but further study is required to determine a causative link.

journal_name

Clin Geriatr Med

authors

Groarke EM,Young NS

doi

10.1016/j.cger.2019.03.001

subject

Has Abstract

pub_date

2019-08-01 00:00:00

pages

285-293

issue

3

eissn

0749-0690

issn

1879-8853

pii

S0749-0690(19)30024-2

journal_volume

35

pub_type

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