Abstract：
:Lassa virus (LASV) is an emerging zoonotic virus endemic in West Africa that can cause severe haemorrhagic Lassa fever (LF) in humans. LF recently gained international attention as a prominent infectious disease, leading to increasingly severe outbreaks in Nigeria over the past three years. Morbidity and mortality associated with LF disease in Nigeria continue to rise with 106 deaths reported in 2016, 143 in 2017 and 562 in 2018. Despite the significant health impact LF imposes on West Africa there are currently no FDA-approved therapeutics or vaccines available for treatment and prevention. This review focuses on the assessment and current state of LF antiviral therapeutics in animal models and their potential role in reducing disease burden throughout West Africa.
journal_name
Curr Opin Viroljournal_title
Current opinion in virologyauthors
Warner BM,Siragam V,Stein DRdoi
10.1016/j.coviro.2019.06.010subject
Has Abstractpub_date
2019-08-01 00:00:00pages
84-90eissn
1879-6257issn
1879-6265pii
S1879-6257(19)30045-8journal_volume
37pub_type
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journal_title：Current opinion in virology
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journal_title：Current opinion in virology
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journal_title：Current opinion in virology
pub_type： 杂志文章,评审
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journal_title：Current opinion in virology
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journal_title：Current opinion in virology
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journal_title：Current opinion in virology
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journal_title：Current opinion in virology
pub_type： 杂志文章,评审
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journal_title：Current opinion in virology
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journal_title：Current opinion in virology
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journal_title：Current opinion in virology
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journal_title：Current opinion in virology
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