Abstract:
:Glucocorticoids are first-line therapy for children with idiopathic nephrotic syndrome (INS). These children are at risk of deranged bone metabolism and low bone mineral density (BMD). We studied 60 children with INS and divided them into two groups. Group 1 included 21 children (initial and infrequent relapsing) and group 2 included 39 children (frequent relapsing, steroid dependent and steroid resistant). Dual-energy X-ray absorptiometry of the lumbar spine was performed to assess BMD. Mean BMD Z-score was compared in both groups; this correlated significantly on univariate analysis with cumulative steroid dose, serum vitamin D levels and calcium supplementation. However, on multivariate analysis, serum vitamin D level was the only factor significantly predictive of low z-score.
journal_name
Trop Doctjournal_title
Tropical doctorauthors
Sharawat IK,Dawman L,Kumkhaniya MV,Devpura K,Mehta Adoi
10.1177/0049475519868055subject
Has Abstractpub_date
2019-10-01 00:00:00pages
292-298issue
4eissn
0049-4755issn
1758-1133journal_volume
49pub_type
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