Abstract:
:Esophageal squamous cell carcinoma (ESCC) is one of the most common types of cancer worldwide. However, operative diagnostic and prognostic systems for ESCC remain to be established. To improve assessment of the prognosis for patients with ESCC, the present study developed an online consensus survival tool for ESCC, termed OSescc. OSescc was built using 264 ESCC cases with gene expression data and relevant clinical information obtained from the Gene Expression Omnibus and The Cancer Genome Atlas databases. Kaplan-Meier survival plots with hazard ratios and P-values were generated by OSescc to predict the association between potential biomarkers and relapse free survival and overall survival. In addition, the current study integrated a function by which one could assess the prognosis based on an individual probe or the mean value of multiple probes for each gene, which helped improve the evaluation of the validity and reliability of the potential prognosis biomarkers. OSescc can be accessed at bioinfo.henu.edu.cn/DBList.jsp.
journal_name
Oncol Lettjournal_title
Oncology lettersauthors
Wang Q,Wang F,Lv J,Xin J,Xie L,Zhu W,Tang Y,Li Y,Zhao X,Wang Y,Li X,Guo Xdoi
10.3892/ol.2019.10440subject
Has Abstractpub_date
2019-08-01 00:00:00pages
1199-1206issue
2eissn
1792-1074issn
1792-1082pii
OL-0-0-10440journal_volume
18pub_type
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