Abstract：
Objectives:This study is aimed at gaining insights on the changing prevalence, economic burden, and catastrophic costs of diabetes in rural southwest China. Materials and Methods:Data were collected from two cross-sectional health interviews and examination surveys among individuals aged ≥ 35 years in rural Yunnan Province. A prevalence-based cost-of-illness method was used to estimate the cost of diabetes. Information about the participants' demographic characteristics and economic consequences of diabetes was obtained using a standard questionnaire. Fasting blood sugar levels were recorded for each study participant. Results:During the study period, the overall prevalence of diabetes increased from 7.7% to 9.5% (P < 0.01) and the economic cost of diabetes increased 1.52-fold. The largest increases were observed in hospital costs (1.77-fold increase), while unit medication costs fell by 18.6%. Both in 2009 and in 2016, males had higher overall direct and indirect costs of diabetes than females (P < 0.05). Direct costs represented the largest component of economic cost of diabetes while hospital costs were the main drivers of direct medical expenditures, accounting for 66.2% of the total direct costs in 2009 and 75.9% in 2016. The incidence of household catastrophic health payment and household impoverishment due to diabetes was 24.0% and 17.9% in 2009 and 23.6% and 17.6% in 2016, respectively. These rates did not differ between the two survey years (P > 0.05). Conclusions:The prevalence and economic burden of diabetes increased substantially from 2009 to 2016 in rural southwest China. The findings underscore an urgent need for the government to invest more financial resources in the prevention of diabetes and improvement of access to affordable medication in rural southwest China.
journal_name
J Diabetes Resjournal_title
Journal of diabetes researchauthors
Li HF,Cai L,Golden ARdoi
10.1155/2019/9626413subject
Has Abstractpub_date
2019-08-01 00:00:00pages
9626413eissn
2314-6745issn
2314-6753journal_volume
2019pub_type
杂志文章abstract：:The aim of this study was to investigate the relationship between serum 25-hydroxy vitamin D (25-OHD) and insulin sensitivity and β-cell function in newly diagnosed type 2 diabetes. 395 newly diagnosed type 2 diabetes patients were enrolled in this study. Venous blood samples were collected at 0 min, 30 min, and 120 m...
journal_title：Journal of diabetes research
pub_type： 杂志文章
doi：10.1155/2015/636891
更新日期：2015-01-01 00:00:00
abstract：:The proliferation of vascular smooth muscle cells (VSMCs) is one of the main features of atherosclerosis induced by high glucose. Mevalonate pathway is an important metabolic pathway that plays a key role in multiple cellular processes. The aim of this study was to define whether the enzyme expression in mevalonate pa...
journal_title：Journal of diabetes research
pub_type： 杂志文章
doi：10.1155/2015/379287
更新日期：2015-01-01 00:00:00
abstract：:The hypoalbuminuric effect of sulodexide (SDX) on diabetic kidney disease (DKD) was suggested by some clinical trials but was denied by the Collaborative Study Group. In this study, the diabetic rats were treated with SDX either from week 0 to 24 or from week 13 to 24. We found that 24-week treatment significantly dec...
journal_title：Journal of diabetes research
pub_type： 杂志文章
doi：10.1155/2017/4989847
更新日期：2017-01-01 00:00:00
abstract：:The quantitative trait locus (QTL) mapping in segregating crosses of NSY (Nagoya-Shibata-Yasuda) mice, an animal model of type 2 diabetes, with nondiabetic strain C3H/He mice has identified diabetogenic QTLs on multiple chromosomes. The QTL on chromosome 11 (Chr11) (Nidd1n) showing the largest effect on hyperglycemia ...
journal_title：Journal of diabetes research
pub_type： 杂志文章
doi：10.1155/2013/608923
更新日期：2013-01-01 00:00:00
abstract：:Objectives. To compare the prevalence of diabetic peripheral neuropathy (DPN) and that of cardiac autonomic neuropathy (CAN) between South Asians and White Caucasians with type 2 diabetes and to explore reasons for observed differences. Methods. A cross-sectional study of casually selected South Asian and White Caucas...
journal_title：Journal of diabetes research
pub_type： 杂志文章
doi：10.1155/2017/1273789
更新日期：2017-01-01 00:00:00
abstract：:Despite recent advances in the understanding and management of diabetes mellitus, the prevalence of the disease is increasing unabatedly with resulting disabling and life-reducing consequences to the global human population. The limitations and side effects associated with current antidiabetic therapies have necessita...
journal_title：Journal of diabetes research
pub_type： 杂志文章,评审
doi：10.1155/2016/9737483
更新日期：2016-01-01 00:00:00
abstract：:Glucokinase (GK) plays a critical role in the control of whole-body glucose homeostasis. We investigated the possible effects of a novel glucokinase activator (GKA), HMS5552, to the GK in rats with type 2 diabetes mellitus (T2DM). Male Sprague-Dawley (SD) rats were divided into four groups: control group, diabetic gro...
journal_title：Journal of diabetes research
pub_type： 杂志文章
doi：10.1155/2017/5812607
更新日期：2017-01-01 00:00:00
abstract：:Partial or complete remission from type 2 diabetes was recently observed after bariatric surgeries. Limited data is available about the possibility of inducing diabetes remission through intensive weight reduction. We retrospectively evaluated diabetes remissions after one year of the Weight Achievement and Intensive ...
journal_title：Journal of diabetes research
pub_type： 杂志文章,随机对照试验
doi：10.1155/2015/468704
更新日期：2015-01-01 00:00:00
abstract：:Knowing how to prevent and treat diabetes mellitus (DM) earlier is essential to improving outcomes. Through participating in synthesis and catabolism of glycogen, the liver helps to regulate glucose homeostasis. Viral related liver diseases are associated with glycometabolism disorders, which means effective managemen...
journal_title：Journal of diabetes research
pub_type： 杂志文章,评审
doi：10.1155/2017/5625371
更新日期：2017-01-01 00:00:00
abstract：:South Asians have high prevalence of diabetes, cardiovascular risk, and physical inactivity. Reasons for physical inactivity have not been explored among Asians living within their endogenous environments. During phase 1 of the study, we assessed the physical activity (PA) of the population using a quantitative, descr...
journal_title：Journal of diabetes research
pub_type： 杂志文章
doi：10.1155/2018/4319604
更新日期：2018-03-06 00:00:00
abstract：:Diabetes mellitus is a chronic disease prevalence of which is high and continually growing. Cardiovascular disease continues to be the leading cause of death in patients with T2DM. The prevention of cardiovascular complications and the cardiovascular safety of treatments should be a primary objective when selecting tr...
journal_title：Journal of diabetes research
pub_type： 杂志文章,评审
doi：10.1155/2018/4020492
更新日期：2018-04-02 00:00:00
abstract：Introduction:The aim of the present study was to examine placental levels of DUSP9 mRNA and protein and to investigate the potential role of DUSP9 in the development of gestational diabetes mellitus (GDM). Methods:Placental tissues from pregnant women with GDM (n = 17) and normal healthy pregnant women (n = 16) were c...
journal_title：Journal of diabetes research
pub_type： 杂志文章
doi：10.1155/2019/1963178
更新日期：2019-10-20 00:00:00
abstract：Aim:To evaluate the influence of metabolic parameters and the treatment method in children with type 1 diabetes (T1D) on the optical coherence tomography angiography (OCTA) results as early markers of diabetic retinopathy (DR). Material and Methods. This prospective study enrolled 175 consecutive children with T1D. OCT...
journal_title：Journal of diabetes research
pub_type： 杂志文章
doi：10.1155/2020/4742952
更新日期：2020-11-18 00:00:00
abstract：Purpose:Because thyroid hormones from the maternal thyroid glands are known to influence the growth, development, and metabolic functioning of offspring, we used a rat model to preliminarily investigate the effects of maternal hypothyroidism on glucose metabolism, pancreas cell proliferation, and insulin production in ...
journal_title：Journal of diabetes research
pub_type： 杂志文章
doi：10.1155/2019/4713906
更新日期：2019-02-21 00:00:00
abstract：:According to the American Diabetes Association (ADA), the side effects of diabetes mellitus have recently increased the global health expenditure each year. Of these, the early diagnostic can contribute to the decrease on renal, cardiovascular, and nervous systems complications. However, the diagnostic criteria, which...
journal_title：Journal of diabetes research
pub_type： 杂志文章
doi：10.1155/2016/8483537
更新日期：2016-01-01 00:00:00
abstract：:The retinal vascular system is the only part of the human body available for direct, in vivo inspection. Noninvasive retinal markers are important to identity patients in risk of sight-threatening diabetic retinopathy. Studies have correlated structural features like retinal vascular caliber and fractals with micro- a...
journal_title：Journal of diabetes research
pub_type： 杂志文章,评审
doi：10.1155/2017/2562759
更新日期：2017-01-01 00:00:00
abstract：Objective:The objective of this study is to investigate the relationship between time in range (TIR), a new metric of continuous glucose monitoring (CGM) and cardiovascular autonomic neuropathy (CAN) in individuals with type 2 diabetes mellitus (T2DM). Methods:A total of 349 individuals with T2DM were enrolled in this...
journal_title：Journal of diabetes research
pub_type： 杂志文章
doi：10.1155/2020/5817074
更新日期：2020-02-06 00:00:00
abstract：:Clopidogrel (INN), an oral antiplatelet drug, has been revealed to have a number of biological properties, for instance, anti-inflammation and antioxidation. Oxidative stress plays an imperative role in inflammation, diabetes mellitus, atherosclerosis, and cancer. In the present study, human aortic endothelial cells (...
journal_title：Journal of diabetes research
pub_type： 杂志文章
doi：10.1155/2016/9128050
更新日期：2016-01-01 00:00:00
abstract：:The aim of this study was to assess the association between OGTT glucose levels and requirement of pharmacotherapy in GDM patients classified by the IADPSG criteria. This study included 203 GDM patients (108 managed with lifestyle modification and 95 requiring pharmacotherapy). Clinical risk factors and OGTT glucose c...
journal_title：Journal of diabetes research
pub_type： 杂志文章
doi：10.1155/2018/3243754
更新日期：2018-05-08 00:00:00
abstract：:The complex diagnosis and treatment of diabetes highlight the need for markers to define how to monitor patients correctly during the course of their disease. Different studies demonstrate the existence of patients who cannot be clearly classified. We have previously shown that it is possible to differentiate "atypica...
journal_title：Journal of diabetes research
pub_type： 杂志文章
doi：10.1155/2015/485132
更新日期：2015-01-01 00:00:00
abstract：:Aims. To examine whether fibrinogen levels are a valuable biomarker for assessing disease severity and monitoring disease progression in patients with diabetic foot ulcer (DFU). Methods. A retrospective study was designed to examine the utility of fibrinogen in estimating disease severity in patients with DFU admitted...
journal_title：Journal of diabetes research
pub_type： 杂志文章
doi：10.1155/2016/2358321
更新日期：2016-01-01 00:00:00
abstract：:Persons with type 2 diabetes mellitus (T2DM) have an elevated risk of atherosclerosis. High-density lipoproteins (HDL) normally protect against cardiovascular disease (CVD), but this may be attenuated by serum amyloid A (SAA). In a case-control study of young females, blood samples were compared between subjects with ...
journal_title：Journal of diabetes research
pub_type： 杂志文章
doi：10.1155/2017/1314864
更新日期：2017-01-01 00:00:00
abstract：:A growing body of evidence suggests yogic practices may benefit adults with type 2 diabetes (DM2). In this systematic review, we evaluate available evidence from prospective controlled trials regarding the effects of yoga-based programs on specific health outcomes pertinent to DM2 management. To identify qualifying st...
journal_title：Journal of diabetes research
pub_type： 杂志文章,评审
doi：10.1155/2016/6979370
更新日期：2016-01-01 00:00:00
abstract：Background:Maternal dietary patterns play an important role in the progress of gestational diabetes mellitus (GDM). The aim of the present study was to explore this association. Method:A total of 388 pregnant women (122 case and 266 control) were included. Dietary intake were collected using a food frequency questionn...
journal_title：Journal of diabetes research
pub_type： 杂志文章
doi：10.1155/2017/5173926
更新日期：2017-01-01 00:00:00
abstract：:This study determined if blocking ligand occupancy of the αVβ3 integrin could inhibit the pathophysiologic changes that occur in the early stages of diabetic nephropathy (DN). Diabetic rats were treated with either vehicle or a monoclonal antibody that binds the β3 subunit of the αVβ3 integrin. After 4 weeks of diabet...
journal_title：Journal of diabetes research
pub_type： 杂志文章
doi：10.1155/2014/421827
更新日期：2014-01-01 00:00:00
abstract：:Immune and inflammatory pathways play a central role in the pathogenesis of diabetic liver injury. Celastrol is a potent immunosuppressive and anti-inflammatory agent. So far, there is no evidence regarding the mechanism of innate immune alterations of celastrol on diabetic liver injury in type 2 diabetic animal model...
journal_title：Journal of diabetes research
pub_type： 杂志文章
doi：10.1155/2016/2641248
更新日期：2016-01-01 00:00:00
abstract：:Most patients with type 2 diabetes (T2D) have suboptimal adherence to recommended diet, physical activity, and/or medication. Current approaches to improve health behaviors in T2D have been variably effective, and successful interventions are often complex and intensive. It is therefore vital to develop interventions ...
journal_title：Journal of diabetes research
pub_type： 杂志文章,评审
doi：10.1155/2015/428349
更新日期：2015-01-01 00:00:00
abstract：:The aim of this study is to evaluate the effects of regular moderate exercise training initiated previously or after induction of diabetes mellitus on renal oxidative stress and inflammation in STZ-induced diabetic female rats. For this purpose, Wistar rats were divided into five groups: sedentary control (SC), traine...
journal_title：Journal of diabetes research
pub_type： 杂志文章
doi：10.1155/2018/6170352
更新日期：2018-03-29 00:00:00
abstract：Purpose:Pancreatic stone protein/regenerating protein I (PSP/REG Iα) is a secretory protein mainly detected in the pancreas. Recent studies revealed increased serum PSP/REG Iα) is a secretory protein mainly detected in the pancreas. Recent studies revealed increased serum PSP/REG Iα) is a secretory protein mainly detec...
journal_title：Journal of diabetes research
pub_type： 杂志文章
doi：10.1155/2020/9787839
更新日期：2020-03-23 00:00:00
abstract：:Diabetic nephropathy (DN) is one of the most common causes of end-stage renal failure. This study was performed to determine the effect of Dantonic Pill (DP) treatment on β -catenin expression in a rat model of streptozotocin- (STZ-) induced early-stage DN, with irbesartan treatment as a positive control. Including an...
journal_title：Journal of diabetes research
pub_type： 杂志文章
doi：10.1155/2013/848679
更新日期：2013-01-01 00:00:00
